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Robert A. Harris
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Journal Articles

PDK4 Augments ER–Mitochondria Contact to Dampen Skeletal Muscle Insulin Signaling During Obesity

Themis Thoudam, Chae-Myeong Ha, Jaechan Leem, Dipanjan Chanda, Jong-Seok Park, Hyo-Jeong Kim, Jae-Han Jeon, Yeon-Kyung Choi, Suthat Liangpunsakul, Yang Hoon Huh, Tae-Hwan Kwon, Keun-Gyu Park, Robert A. Harris, Kyu-Sang Park, Hyun-Woo Rhee, In-Kyu Lee
Journal: Diabetes
Diabetes 2019;68(3):571–586
https://doi.org/10.2337/db18-0363
Published: 06 December 2018
View article titled, PDK4 Augments ER–Mitochondria Contact to Dampen Skeletal Muscle Insulin Signaling During Obesity
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Includes: Supplementary data
Journal Articles

PDK4 Deficiency Suppresses Hepatic Glucagon Signaling by Decreasing cAMP Levels

Bo-Yoon Park, Jae-Han Jeon, Younghoon Go, Hye Jin Ham, Jeong-Eun Kim, Eun Kyung Yoo, Woong Hee Kwon, Nam-Ho Jeoung, Yong Hyun Jeon, Seung-Hoi Koo, Byung-Gyu Kim, Ling He, Keun-Gyu Park, Robert A. Harris, In-Kyu Lee
Journal: Diabetes
Diabetes 2018;67(10):2054–2068
https://doi.org/10.2337/db17-1529
Published: 31 July 2018
View article titled, PDK4 Deficiency Suppresses Hepatic Glucagon Signaling by Decreasing cAMP Levels
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Includes: Supplementary data
Journal Articles

Inhibition of Pyruvate Dehydrogenase Kinase 2 Protects Against Hepatic Steatosis Through Modulation of Tricarboxylic Acid Cycle Anaplerosis and Ketogenesis

Younghoon Go, Ji Yun Jeong, Nam Ho Jeoung, Jae-Han Jeon, Bo-Yoon Park, Hyeon-Ji Kang, Chae-Myeong Ha, Young-Keun Choi, Sun Joo Lee, Hye Jin Ham, Byung-Gyu Kim, Keun-Gyu Park, So Young Park, Chul-Ho Lee, Cheol Soo Choi, Tae-Sik Park, W.N. Paul Lee, Robert A. Harris, In-Kyu Lee
Journal: Diabetes
Diabetes 2016;65(10):2876–2887
https://doi.org/10.2337/db16-0223
Published: 06 July 2016
View article titled, Inhibition of Pyruvate Dehydrogenase Kinase 2 Protects Against Hepatic Steatosis Through Modulation of Tricarboxylic Acid Cycle Anaplerosis and Ketogenesis
Open the PDF for Inhibition of Pyruvate Dehydrogenase Kinase 2 Protects Against Hepatic Steatosis Through Modulation of Tricarboxylic Acid Cycle Anaplerosis and Ketogenesis in another window
Includes: Supplementary data
Journal Articles

O-GlcNAcylation of Orphan Nuclear Receptor Estrogen-Related Receptor γ Promotes Hepatic Gluconeogenesis

Jagannath Misra, Don-Kyu Kim, Yoon Seok Jung, Han Byeol Kim, Yong-Hoon Kim, Eun-Kyung Yoo, Byung Gyu Kim, Sunghoon Kim, In-Kyu Lee, Robert A. Harris, Jeong-Sun Kim, Chul-Ho Lee, Jin Won Cho, Hueng-Sik Choi
Journal: Diabetes
Diabetes 2016;65(10):2835–2848
https://doi.org/10.2337/db15-1523
Published: 22 June 2016
View article titled, O-GlcNAcylation of Orphan Nuclear Receptor Estrogen-Related Receptor γ Promotes Hepatic Gluconeogenesis
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Includes: Supplementary data
Journal Articles

Nitric Oxide Produced by Macrophages Inhibits Adipocyte Differentiation and Promotes Profibrogenic Responses in Preadipocytes to Induce Adipose Tissue Fibrosis

Jung Eun Jang, Myoung Seok Ko, Ji-Young Yun, Mi-Ok Kim, Jin Hee Kim, Hye Sun Park, Ah-Ram Kim, Hyuk-Joong Kim, Bum Joong Kim, Young Eun Ahn, Jin Sun Oh, Woo Je Lee, Robert A. Harris, Eun Hee Koh, Ki-Up Lee
Journal: Diabetes
Diabetes 2016;65(9):2516–2528
https://doi.org/10.2337/db15-1624
Published: 31 May 2016
View article titled, Nitric Oxide Produced by Macrophages Inhibits Adipocyte Differentiation and Promotes Profibrogenic Responses in Preadipocytes to Induce Adipose Tissue Fibrosis
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Includes: Supplementary data
Journal Articles

Insulin-Inducible SMILE Inhibits Hepatic Gluconeogenesis

Ji-Min Lee, Woo-Young Seo, Hye-Sook Han, Kyoung-Jin Oh, Yong-Soo Lee, Don-Kyu Kim, Seri Choi, Byeong Hun Choi, Robert A. Harris, Chul-Ho Lee, Seung-Hoi Koo, Hueng-Sik Choi
Journal: Diabetes
Diabetes 2016;65(1):62–73
https://doi.org/10.2337/db15-0249
Published: 04 September 2015
View article titled, Insulin-Inducible SMILE Inhibits Hepatic Gluconeogenesis
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Includes: Supplementary data
Journal Articles

Adoptive Transfer of Immunomodulatory M2 Macrophages Prevents Type 1 Diabetes in NOD Mice

Roham Parsa, Pernilla Andresen, Alan Gillett, Sohel Mia, Xing-Mei Zhang, Sofia Mayans, Dan Holmberg, Robert A. Harris
Journal: Diabetes
Diabetes 2012;61(11):2881–2892
https://doi.org/10.2337/db11-1635
Published: 16 October 2012
View article titled, Adoptive Transfer of Immunomodulatory M2 Macrophages Prevents Type 1 Diabetes in NOD Mice
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Includes: Multimedia, Supplementary data
Journal Articles

Metformin Inhibits Growth Hormone–Mediated Hepatic PDK4 Gene Expression Through Induction of Orphan Nuclear Receptor Small Heterodimer Partner

Yong Deuk Kim, Yong-Hoon Kim, Surendar Tadi, Ji Hoon Yu, Yong-Hyeon Yim, Nam Ho Jeoung, Minho Shong, Lothar Hennighausen, Robert A. Harris, In-Kyu Lee, Chul-Ho Lee, Hueng-Sik Choi
Journal: Diabetes
Diabetes 2012;61(10):2484–2494
https://doi.org/10.2337/db11-1665
Published: 13 September 2012
View article titled, Metformin Inhibits Growth Hormone–Mediated Hepatic <em>PDK4</em> Gene Expression Through Induction of Orphan Nuclear Receptor Small Heterodimer Partner
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Includes: Supplementary data
Journal Articles

Effects of Insulin Replacements, Inhibitors of Angiotensin, and PKCβ's Actions to Normalize Cardiac Gene Expression and Fuel Metabolism in Diabetic Rats

Emi Arikawa, Ronald C.W. Ma, Keiji Isshiki, Ivan Luptak, Zhiheng He, Yutaka Yasuda, Yasuhiro Maeno, Mary Elizabeth Patti, Gordon C. Weir, Robert A. Harris, Victor A. Zammit, Rong Tian, George L. King
Journal: Diabetes
Diabetes 2007;56(5):1410–1420
https://doi.org/10.2337/db06-0655
Published: 01 May 2007
View article titled, Effects of Insulin Replacements, Inhibitors of Angiotensin, and PKCβ's Actions to Normalize Cardiac Gene Expression and Fuel Metabolism in Diabetic Rats
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Journal Articles

Protein Kinase B-α Inhibits Human Pyruvate Dehydrogenase Kinase-4 Gene Induction by Dexamethasone Through Inactivation of FOXO Transcription Factors

Hye-Sook Kwon, Boli Huang, Terry G. Unterman, Robert A. Harris
Journal: Diabetes
Diabetes 2004;53(4):899–910
https://doi.org/10.2337/diabetes.53.4.899
Published: 01 April 2004
View article titled, Protein Kinase B-α Inhibits Human Pyruvate Dehydrogenase Kinase-4 Gene Induction by Dexamethasone Through Inactivation of FOXO Transcription Factors
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Journal Articles

Starvation and Diabetes Reduce the Amount of Pyruvate Dehydrogenase Phosphatase in Rat Heart and Kidney

Boli Huang, Pengfei Wu, Kirill M. Popov, Robert A. Harris
Journal: Diabetes
Diabetes 2003;52(6):1371–1376
https://doi.org/10.2337/diabetes.52.6.1371
Published: 01 June 2003
View article titled, Starvation and Diabetes Reduce the Amount of Pyruvate Dehydrogenase Phosphatase in Rat Heart and Kidney
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Journal Articles

Regulation of Pyruvate Dehydrogenase Kinase Expression by Peroxisome Proliferator–Activated Receptor-α Ligands, Glucocorticoids, and Insulin

Boli Huang, Pengfei Wu, Melissa M. Bowker-Kinley, Robert A. Harris
Journal: Diabetes
Diabetes 2002;51(2):276–283
https://doi.org/10.2337/diabetes.51.2.276
Published: 01 February 2002
View article titled, Regulation of Pyruvate Dehydrogenase Kinase Expression by Peroxisome Proliferator–Activated Receptor-α Ligands, Glucocorticoids, and Insulin
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Journal Articles

Short-term Hormonal Control of Hepatic Lipogenesis

Math J H Geelen, Robert A Harris, Anton C Beynen, Sylvia A McCune
Journal: Diabetes
Diabetes 1980;29(12):1006–1022
https://doi.org/10.2337/diab.29.12.1006
Published: 01 December 1980
View article titled, Short-term Hormonal Control of Hepatic Lipogenesis
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