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Robert S Sherwin
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Journal Articles

Glycemic Variability and Brain Glucose Levels in Type 1 Diabetes

Janice J. Hwang, Lihong Jiang, Elizabeth Sanchez Rangel, Xiaoning Fan, Yuyan Ding, Wai Lam, Jessica Leventhal, Feng Dai, Douglas L. Rothman, Graeme F. Mason, Robert S. Sherwin
Journal: Diabetes
Diabetes 2019;68(1):163–171
https://doi.org/10.2337/db18-0722
Published: 16 October 2018
View article titled, Glycemic Variability and Brain Glucose Levels in Type 1 Diabetes
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Includes: Supplementary data
Journal Articles

Altered Brain Response to Drinking Glucose and Fructose in Obese Adolescents

Ania M. Jastreboff, Rajita Sinha, Jagriti Arora, Cosimo Giannini, Jessica Kubat, Saima Malik, Michelle A. Van Name, Nicola Santoro, Mary Savoye, Elvira J. Duran, Bridget Pierpont, Gary Cline, R. Todd Constable, Robert S. Sherwin, Sonia Caprio
Journal: Diabetes
Diabetes 2016;65(7):1929–1939
https://doi.org/10.2337/db15-1216
Published: 05 April 2016
View article titled, Altered Brain Response to Drinking Glucose and Fructose in Obese Adolescents
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Includes: Supplementary data
Journal Articles

Is There Cross Talk Between Portal and Hypothalamic Glucose-Sensing Circuits?

Owen Chan, Robert S. Sherwin
Journal: Diabetes
Diabetes 2014;63(8):2617–2619
https://doi.org/10.2337/db14-0755
Published: 17 July 2014
View article titled, Is There Cross Talk Between Portal and Hypothalamic Glucose-Sensing Circuits?
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Journal Articles

Role of Synaptic Plasticity and EphA5-EphrinA5 Interaction Within the Ventromedial Hypothalamus in Response to Recurrent Hypoglycemia

Barbara Szepietowska, Tamas L. Horvath, Robert S. Sherwin
Journal: Diabetes
Diabetes 2014;63(3):1140–1147
https://doi.org/10.2337/db13-1259
Published: 13 February 2014
View article titled, Role of Synaptic Plasticity and EphA5-EphrinA5 Interaction Within the Ventromedial Hypothalamus in Response to Recurrent Hypoglycemia
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Journal Articles

Functional MRI Signal Fluctuations: A Preclinical Biomarker for Cognitive Impairment in Type 2 Diabetes?

Renata Belfort-DeAguiar, R. Todd Constable, Robert S. Sherwin
Journal: Diabetes
Diabetes 2014;63(2):396–398
https://doi.org/10.2337/db13-1685
Published: 16 January 2014
View article titled, Functional MRI Signal Fluctuations: A Preclinical Biomarker for Cognitive Impairment in Type 2 Diabetes?
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Journal Articles

Lactate-Induced Release of GABA in the Ventromedial Hypothalamus Contributes to Counterregulatory Failure in Recurrent Hypoglycemia and Diabetes

Owen Chan, Sachin A. Paranjape, Adam Horblitt, Wanling Zhu, Robert S. Sherwin
Journal: Diabetes
Diabetes 2013;62(12):4239–4246
https://doi.org/10.2337/db13-0770
Published: 16 November 2013
View article titled, Lactate-Induced Release of GABA in the Ventromedial Hypothalamus Contributes to Counterregulatory Failure in Recurrent Hypoglycemia and Diabetes
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Includes: Supplementary data
Journal Articles

EphA5-EphrinA5 Interactions Within the Ventromedial Hypothalamus Influence Counterregulatory Hormone Release and Local Glutamine/Glutamate Balance During Hypoglycemia

Barbara Szepietowska, Wanling Zhu, Jan Czyzyk, Tore Eid, Robert S. Sherwin
Journal: Diabetes
Diabetes 2013;62(4):1282–1288
https://doi.org/10.2337/db12-0982
Published: 14 March 2013
View article titled, EphA5-EphrinA5 Interactions Within the Ventromedial Hypothalamus Influence Counterregulatory Hormone Release and Local Glutamine/Glutamate Balance During Hypoglycemia
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Journal Articles

Hypothalamic Regulation of Glucose-Stimulated Insulin Secretion

Owen Chan, Robert S. Sherwin
Journal: Diabetes
Diabetes 2012;61(3):564–565
https://doi.org/10.2337/db11-1846
Published: 13 February 2012
View article titled, Hypothalamic Regulation of Glucose-Stimulated Insulin Secretion
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Journal Articles

Modulation of β-Adrenergic Receptors in the Ventromedial Hypothalamus Influences Counterregulatory Responses to Hypoglycemia

Barbara Szepietowska, Wanling Zhu, Owen Chan, Adam Horblitt, James Dziura, Robert S. Sherwin
Journal: Diabetes
Diabetes 2011;60(12):3154–3158
https://doi.org/10.2337/db11-0432
Published: 13 November 2011
View article titled, Modulation of β-Adrenergic Receptors in the Ventromedial Hypothalamus Influences Counterregulatory Responses to Hypoglycemia
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Journal Articles

Insulin-Induced Hypoglycemia and Its Effect on the Brain: Unraveling Metabolism by In Vivo Nuclear Magnetic Resonance

Raimund I. Herzog, Robert S. Sherwin, Douglas L. Rothman
Journal: Diabetes
Diabetes 2011;60(7):1856–1858
https://doi.org/10.2337/db11-0498
Published: 20 June 2011
View article titled, Insulin-Induced Hypoglycemia and Its Effect on the Brain: <subtitle>Unraveling Metabolism by In Vivo Nuclear Magnetic Resonance</subtitle>
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Journal Articles

Hypoglycemia in Type 1 Diabetes

Rory J. McCrimmon, Robert S. Sherwin
Journal: Diabetes
Diabetes 2010;59(10):2333–2339
https://doi.org/10.2337/db10-0103
Published: 01 October 2010
View article titled, Hypoglycemia in Type 1 Diabetes
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Journal Articles

Influence of Insulin in the Ventromedial Hypothalamus on Pancreatic Glucagon Secretion In Vivo

Sachin A. Paranjape, Owen Chan, Wanling Zhu, Adam M. Horblitt, Ewan C. McNay, James A. Cresswell, Jonathan S. Bogan, Rory J. McCrimmon, Robert S. Sherwin
Journal: Diabetes
Diabetes 2010;59(6):1521–1527
https://doi.org/10.2337/db10-0014
Published: 18 March 2010
View article titled, Influence of Insulin in the Ventromedial Hypothalamus on Pancreatic Glucagon Secretion In Vivo
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Journal Articles

Recurrent Antecedent Hypoglycemia Alters Neuronal Oxidative Metabolism In Vivo

Lihong Jiang, Raimund I. Herzog, Graeme F. Mason, Robin A. de Graaf, Douglas L. Rothman, Robert S. Sherwin, Kevin L. Behar
Journal: Diabetes
Diabetes 2009;58(6):1266–1274
https://doi.org/10.2337/db08-1664
Published: 10 March 2009
View article titled, Recurrent Antecedent Hypoglycemia Alters Neuronal Oxidative Metabolism In Vivo
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Includes: Supplementary data
Journal Articles

Medium-Chain Fatty Acids Improve Cognitive Function in Intensively Treated Type 1 Diabetic Patients and Support In Vitro Synaptic Transmission During Acute Hypoglycemia

Kathleen A. Page, Anne Williamson, Namyi Yu, Ewan C. McNay, James Dzuira, Rory J. McCrimmon, Robert S. Sherwin
Journal: Diabetes
Diabetes 2009;58(5):1237–1244
https://doi.org/10.2337/db08-1557
Published: 17 February 2009
View article titled, Medium-Chain Fatty Acids Improve Cognitive Function in Intensively Treated Type 1 Diabetic Patients and Support In Vitro Synaptic Transmission During Acute Hypoglycemia
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Journal Articles

Small Decrements in Systemic Glucose Provoke Increases in Hypothalamic Blood Flow Prior to the Release of Counterregulatory Hormones

Kathleen A. Page, Jagriti Arora, Maolin Qiu, Rachna Relwani, R. Todd Constable, Robert S. Sherwin
Journal: Diabetes
Diabetes 2009;58(2):448–452
https://doi.org/10.2337/db08-1224
Published: 01 February 2009
View article titled, Small Decrements in Systemic Glucose Provoke Increases in Hypothalamic Blood Flow Prior to the Release of Counterregulatory Hormones
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Journal Articles

Amplified Hormonal Counterregulatory Responses to Hypoglycemia in Rats After Systemic Delivery of a SUR-1–Selective K+ Channel Opener?

Xiaoning Fan, Yuyan Ding, Haiying Cheng, Dorte X. Gram, Robert S. Sherwin, Rory J. McCrimmon
Journal: Diabetes
Diabetes 2008;57(12):3327–3334
https://doi.org/10.2337/db08-0793
Published: 01 December 2008
View article titled, Amplified Hormonal Counterregulatory Responses to Hypoglycemia in Rats After Systemic Delivery of a SUR-1–Selective K<sup>+</sup> Channel Opener?
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Journal Articles

Bringing Light to the Dark Side of Insulin: A Journey Across the Blood-Brain Barrier

Robert S. Sherwin
Journal: Diabetes
Diabetes 2008;57(9):2259–2268
https://doi.org/10.2337/db08-9023
Published: 01 September 2008
View article titled, Bringing Light to the Dark Side of Insulin: <subtitle>A Journey Across the Blood-Brain Barrier</subtitle>
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Journal Articles

Increased GABAergic Tone in the Ventromedial Hypothalamus Contributes to Suppression of Counterregulatory Reponses After Antecedent Hypoglycemia

Owen Chan, Haiying Cheng, Raimund Herzog, Daniel Czyzyk, Wanling Zhu, Ajin Wang, Rory J. McCrimmon, Margretta R. Seashore, Robert S. Sherwin
Journal: Diabetes
Diabetes 2008;57(5):1363–1370
https://doi.org/10.2337/db07-1559
Published: 01 May 2008
View article titled, Increased GABAergic Tone in the Ventromedial Hypothalamus Contributes to Suppression of Counterregulatory Reponses After Antecedent Hypoglycemia
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Includes: Supplementary data
Journal Articles

Key Role for AMP-Activated Protein Kinase in the Ventromedial Hypothalamus in Regulating Counterregulatory Hormone Responses to Acute Hypoglycemia

Rory J. McCrimmon, Margaret Shaw, Xiaoning Fan, Haiying Cheng, Yuyan Ding, Monica C. Vella, Ligang Zhou, Ewan C. McNay, Robert S. Sherwin
Journal: Diabetes
Diabetes 2008;57(2):444–450
https://doi.org/10.2337/db07-0837
Published: 01 February 2008
View article titled, Key Role for AMP-Activated Protein Kinase in the Ventromedial Hypothalamus in Regulating Counterregulatory Hormone Responses to Acute Hypoglycemia
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Journal Articles

ATP-Sensitive K+ Channels Regulate the Release of GABA in the Ventromedial Hypothalamus During Hypoglycemia

Owen Chan, Marcus Lawson, Wanling Zhu, Joseph Lee Beverly, Robert S. Sherwin
Journal: Diabetes
Diabetes 2007;56(4):1120–1126
https://doi.org/10.2337/db06-1102
Published: 01 April 2007
View article titled, ATP-Sensitive K<sup>+</sup> Channels Regulate the Release of GABA in the Ventromedial Hypothalamus During Hypoglycemia
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