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Robert V. Farese
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Journal Articles

Deletion of Protein Kinase C λ in POMC Neurons Predisposes to Diet-Induced Obesity

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Mauricio D. Dorfman, Jordan E. Krull, Jarrad M. Scarlett, Stephan J. Guyenet, Mini P. Sajan, Vincent Damian, Hong T. Nguyen, Michael Leitges, Gregory J. Morton, Robert V. Farese, Michael W. Schwartz, Joshua P. Thaler
Journal: Diabetes
Diabetes 2017;66(4):920–934
https://doi.org/10.2337/db16-0482
Published: 10 January 2017
View articletitled, Deletion of Protein Kinase C λ in POMC Neurons Predisposes to Diet-Induced Obesity
Open the PDF for Deletion of Protein Kinase C λ in POMC Neurons Predisposes to Diet-Induced Obesity in another window
Includes: Supplementary data
Journal Articles

Brain Insulin Signaling Is Increased in Insulin-Resistant States and Decreases in FOXOs and PGC-1α and Increases in Aβ1–40/42 and Phospho-Tau May Abet Alzheimer Development

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Mini Sajan, Barbara Hansen, Robert Ivey, III, Joshua Sajan, Csilla Ari, Shijie Song, Ursula Braun, Michael Leitges, Margaret Farese-Higgs, Robert V. Farese
Journal: Diabetes
Diabetes 2016;65(7):1892–1903
https://doi.org/10.2337/db15-1428
Published: 19 February 2016
View articletitled, Brain Insulin Signaling Is Increased in Insulin-Resistant States and Decreases in FOXOs and PGC-1α and Increases in Aβ1–40/42 and Phospho-Tau May Abet Alzheimer Development
Open the PDF for Brain Insulin Signaling Is Increased in Insulin-Resistant States and Decreases in FOXOs and PGC-1α and Increases in Aβ1–40/42 and Phospho-Tau May Abet Alzheimer Development in another window
Includes: Supplementary data
Journal Articles

Akt-Dependent Phosphorylation of Hepatic FoxO1 Is Compartmentalized on a WD40/ProF Scaffold and Is Selectively Inhibited by aPKC in Early Phases of Diet-Induced Obesity

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Mini P. Sajan, Mildred E. Acevedo-Duncan, Mary L. Standaert, Robert A. Ivey, Mackenzie Lee, Robert V. Farese
Journal: Diabetes
Diabetes 2014;63(8):2690–2701
https://doi.org/10.2337/db13-1863
Published: 17 July 2014
View articletitled, Akt-Dependent Phosphorylation of Hepatic FoxO1 Is Compartmentalized on a WD40/ProF Scaffold and Is Selectively Inhibited by aPKC in Early Phases of Diet-Induced Obesity
Open the PDF for Akt-Dependent Phosphorylation of Hepatic FoxO1 Is Compartmentalized on a WD40/ProF Scaffold and Is Selectively Inhibited by aPKC in Early Phases of Diet-Induced Obesity in another window
Includes: Supplementary data
Journal Articles

Role of Adipocyte-Derived Factors in Enhancing Insulin Signaling in Skeletal Muscle and White Adipose Tissue of Mice Lacking Acyl CoA:Diacylglycerol Acyltransferase 1

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Hubert C. Chen, Meghana Rao, Mini P. Sajan, Mary Standaert, Yoshinori Kanoh, Atsushi Miura, Robert V. Farese, Jr., Robert V. Farese
Journal: Diabetes
Diabetes 2004;53(6):1445–1451
https://doi.org/10.2337/diabetes.53.6.1445
Published: 01 June 2004
View articletitled, Role of Adipocyte-Derived Factors in Enhancing Insulin Signaling in Skeletal Muscle and White Adipose Tissue of Mice Lacking Acyl CoA:Diacylglycerol Acyltransferase 1
Open the PDF for Role of Adipocyte-Derived Factors in Enhancing Insulin Signaling in Skeletal Muscle and White Adipose Tissue of Mice Lacking Acyl CoA:Diacylglycerol Acyltransferase 1 in another window
Journal Articles

Activation of Protein Kinase C-ζ by Insulin and Phosphatidylinositol-3,4,5-(PO4)3 Is Defective in Muscle in Type 2 Diabetes and Impaired Glucose Tolerance: Amelioration by Rosiglitazone and Exercise

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Mary Beeson, Mini P. Sajan, Michelle Dizon, Dmitry Grebenev, Joaquin Gomez-Daspet, Atsushi Miura, Yoshinori Kanoh, Jennifer Powe, Gautam Bandyopadhyay, Mary L. Standaert, Robert V. Farese
Journal: Diabetes
Diabetes 2003;52(8):1926–1934
https://doi.org/10.2337/diabetes.52.8.1926
Published: 01 August 2003
View articletitled, Activation of Protein Kinase C-ζ by Insulin and Phosphatidylinositol-3,4,5-(PO4)3 Is Defective in Muscle in Type 2 Diabetes and Impaired Glucose Tolerance: Amelioration by Rosiglitazone and Exercise
Open the PDF for Activation of Protein Kinase C-ζ by Insulin and Phosphatidylinositol-3,4,5-(PO4)3 Is Defective in Muscle in Type 2 Diabetes and Impaired Glucose Tolerance: Amelioration by Rosiglitazone and Exercise in another window
Journal Articles

Dissociation of Obesity and Impaired Glucose Disposal in Mice Overexpressing Acyl Coenzyme A:Diacylglycerol Acyltransferase 1 in White Adipose Tissue

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Hubert C. Chen, Scot J. Stone, Ping Zhou, Kimberly K. Buhman, Robert V. Farese, Jr
Journal: Diabetes
Diabetes 2002;51(11):3189–3195
https://doi.org/10.2337/diabetes.51.11.3189
Published: 01 November 2002
View articletitled, Dissociation of Obesity and Impaired Glucose Disposal in Mice Overexpressing Acyl Coenzyme A:Diacylglycerol Acyltransferase 1 in White Adipose Tissue
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Journal Articles

Skeletal Muscle Insulin Resistance in Obesity-Associated Type 2 Diabetes in Monkeys Is Linked to a Defect in Insulin Activation of Protein Kinase C-ζ/λ/ι

Free
Mary L. Standaert, Heidi K. Ortmeyer, Mini P. Sajan, Yoshinori Kanoh, Gautam Bandyopadhyay, Barbara C. Hansen, Robert V. Farese
Journal: Diabetes
Diabetes 2002;51(10):2936–2943
https://doi.org/10.2337/diabetes.51.10.2936
Published: 01 October 2002
View articletitled, Skeletal Muscle Insulin Resistance in Obesity-Associated Type 2 Diabetes in Monkeys Is Linked to a Defect in Insulin Activation of Protein Kinase C-ζ/λ/ι
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Journal Articles

Chronic Activation of Protein Kinase C in Soleus Muscles and Other Tissues of Insulin-Resistant Type II diabetic Goto-Kakizaki (GK), Obese/Aged, and Obese/Zucker Rats: A Mechanism For Inhibiting Glycogen Synthesis

Free
Antoine Avignon, Kouji Yamada, Xiaoping Zhou, Barbara Spencer, Osvaldo Cardona, Shereen Saba-Siddique, Lamar Galloway, Mary L Standaert, Robert V Farese
Journal: Diabetes
Diabetes 1996;45(10):1396–1404
https://doi.org/10.2337/diab.45.10.1396
Published: 01 October 1996
View articletitled, Chronic Activation of Protein Kinase C in Soleus Muscles and Other Tissues of Insulin-Resistant Type II diabetic Goto-Kakizaki (GK), Obese/Aged, and Obese/Zucker Rats: A Mechanism For Inhibiting Glycogen Synthesis
Open the PDF for Chronic Activation of Protein Kinase C in Soleus Muscles and Other Tissues of Insulin-Resistant Type II diabetic Goto-Kakizaki (GK), Obese/Aged, and Obese/Zucker Rats: A Mechanism For Inhibiting Glycogen Synthesis in another window
Journal Articles

Downregulation of Protein Kinase C and Insulin-Stimulated 2-Deoxyglucose Uptake in Rat Adipocytes by Phorbol Esters, Glucose, and Insulin

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Tatsuo Ishizuka, Denise R Cooper, Thomas Arnold, Herman Hernandez, Robert V Farese
Journal: Diabetes
Diabetes 1991;40(10):1274–1281
https://doi.org/10.2337/diab.40.10.1274
Published: 01 October 1991
View articletitled, Downregulation of Protein Kinase C and Insulin-Stimulated 2-Deoxyglucose Uptake in Rat Adipocytes by Phorbol Esters, Glucose, and Insulin
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Journal Articles

Sulfonylurea-Stimulated Glucose Transport Association With Diacylglycerollike Activation of Protein Kinase C in BC3H1 Myocytes

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Denise R Cooper, Maria C Vila, James E Watson, Govindan Nair, Robert J Pollet, Mary Standaert, Robert V Farese
Journal: Diabetes
Diabetes 1990;39(11):1399–1407
https://doi.org/10.2337/diab.39.11.1399
Published: 01 November 1990
View articletitled, Sulfonylurea-Stimulated Glucose Transport Association With Diacylglycerollike Activation of Protein Kinase C in BC3H1 Myocytes
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Journal Articles

Effects of Insulin on Diacylglycerol–Protein Kinase C Signaling in Rat Diaphragm and Soleus Muscles and Relationship to Glucose Transport

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Tatsuo Ishizuka, Denise R Cooper, Herman Hernandez, Donna Buckley, Mary Standaert, Robert V Farese
Journal: Diabetes
Diabetes 1990;39(2):181–190
https://doi.org/10.2337/diab.39.2.181
Published: 01 February 1990
View articletitled, Effects of Insulin on Diacylglycerol–Protein Kinase C Signaling in Rat Diaphragm and Soleus Muscles and Relationship to Glucose Transport
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Journal Articles

The Mechanism of Action of Insulin on Phospholipid Metabolism in Rat Adipose Tissue: Requirement for Protein Synthesis and a Carbohydrate Source, and Relationship to Activation of Pyruvate Dehydrogenase

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Robert V Farese, Robert V Farese, Jr, Mohammad Ayub Sabir, Ronald E Larson, Walter L Trudeau, III
Journal: Diabetes
Diabetes 1984;33(7):648–655
https://doi.org/10.2337/diab.33.7.648
Published: 01 July 1984
View articletitled, The Mechanism of Action of Insulin on Phospholipid Metabolism in Rat Adipose Tissue: Requirement for Protein Synthesis and a Carbohydrate Source, and Relationship to Activation of Pyruvate Dehydrogenase
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Journal Articles

Insulin and Its Secretagogues Activate Ca2+-dependent Phosphatidylinositol Breakdown and Amylase Secretion in Rat Pancreas In Vitro

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Robert V Farese, Ronald E Larson, Mohammad A Sabir
Journal: Diabetes
Diabetes 1981;30(5):396–401
https://doi.org/10.2337/diab.30.5.396
Published: 01 May 1981
View articletitled, Insulin and Its Secretagogues Activate Ca2+-dependent Phosphatidylinositol Breakdown and Amylase Secretion in Rat Pancreas In Vitro
Open the PDF for Insulin and Its Secretagogues Activate Ca2+-dependent Phosphatidylinositol Breakdown and Amylase Secretion in Rat Pancreas In Vitro in another window