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Journal Articles

Deletion of Protein Kinase C λ in POMC Neurons Predisposes to Diet-Induced Obesity

Mauricio D. Dorfman, Jordan E. Krull, Jarrad M. Scarlett, Stephan J. Guyenet, Mini P. Sajan, Vincent Damian, Hong T. Nguyen, Michael Leitges, Gregory J. Morton, Robert V. Farese, Michael W. Schwartz, Joshua P. Thaler

Diabetes 2017;66(4):920–934

https://doi.org/10.2337/db16-0482

Published: 10 January 2017

View article titled, Deletion of Protein Kinase C λ in POMC Neurons Predisposes to Diet-Induced Obesity

Includes: Supplementary data

Journal Articles

Brain Insulin Signaling Is Increased in Insulin-Resistant States and Decreases in FOXOs and PGC-1α and Increases in Aβ_1–40/42 and Phospho-Tau May Abet Alzheimer Development

Mini Sajan, Barbara Hansen, Robert Ivey, III, Joshua Sajan, Csilla Ari, Shijie Song, Ursula Braun, Michael Leitges, Margaret Farese-Higgs, Robert V. Farese

Diabetes 2016;65(7):1892–1903

https://doi.org/10.2337/db15-1428

Published: 19 February 2016

View article titled, Brain Insulin Signaling Is Increased in Insulin-Resistant States and Decreases in FOXOs and PGC-1α and Increases in Aβ1–40/42 and Phospho-Tau May Abet Alzheimer Development

Includes: Supplementary data

Journal Articles

Akt-Dependent Phosphorylation of Hepatic FoxO1 Is Compartmentalized on a WD40/ProF Scaffold and Is Selectively Inhibited by aPKC in Early Phases of Diet-Induced Obesity

Mini P. Sajan, Mildred E. Acevedo-Duncan, Mary L. Standaert, Robert A. Ivey, Mackenzie Lee, Robert V. Farese

Diabetes 2014;63(8):2690–2701

https://doi.org/10.2337/db13-1863

Published: 17 July 2014

View article titled, Akt-Dependent Phosphorylation of Hepatic FoxO1 Is Compartmentalized on a WD40/ProF Scaffold and Is Selectively Inhibited by aPKC in Early Phases of Diet-Induced Obesity

Includes: Supplementary data

Journal Articles

Role of Adipocyte-Derived Factors in Enhancing Insulin Signaling in Skeletal Muscle and White Adipose Tissue of Mice Lacking Acyl CoA:Diacylglycerol Acyltransferase 1

Hubert C. Chen, Meghana Rao, Mini P. Sajan, Mary Standaert, Yoshinori Kanoh, Atsushi Miura, Robert V. Farese, Jr., Robert V. Farese

Diabetes 2004;53(6):1445–1451

https://doi.org/10.2337/diabetes.53.6.1445

Published: 01 June 2004

View article titled, Role of Adipocyte-Derived Factors in Enhancing Insulin Signaling in Skeletal Muscle and White Adipose Tissue of Mice Lacking Acyl CoA:Diacylglycerol Acyltransferase 1

Journal Articles

Activation of Protein Kinase C-ζ by Insulin and Phosphatidylinositol-3,4,5-(PO₄)₃ Is Defective in Muscle in Type 2 Diabetes and Impaired Glucose Tolerance: Amelioration by Rosiglitazone and Exercise

Mary Beeson, Mini P. Sajan, Michelle Dizon, Dmitry Grebenev, Joaquin Gomez-Daspet, Atsushi Miura, Yoshinori Kanoh, Jennifer Powe, Gautam Bandyopadhyay, Mary L. Standaert, Robert V. Farese

Diabetes 2003;52(8):1926–1934

https://doi.org/10.2337/diabetes.52.8.1926

Published: 01 August 2003

View article titled, Activation of Protein Kinase C-ζ by Insulin and Phosphatidylinositol-3,4,5-(PO4)3 Is Defective in Muscle in Type 2 Diabetes and Impaired Glucose Tolerance: <subtitle>Amelioration by Rosiglitazone and Exercise</subtitle>

Journal Articles

Dissociation of Obesity and Impaired Glucose Disposal in Mice Overexpressing Acyl Coenzyme A:Diacylglycerol Acyltransferase 1 in White Adipose Tissue

Hubert C. Chen, Scot J. Stone, Ping Zhou, Kimberly K. Buhman, Robert V. Farese, Jr

Diabetes 2002;51(11):3189–3195

https://doi.org/10.2337/diabetes.51.11.3189

Published: 01 November 2002

View article titled, Dissociation of Obesity and Impaired Glucose Disposal in Mice Overexpressing Acyl Coenzyme A:Diacylglycerol Acyltransferase 1 in White Adipose Tissue

Journal Articles

Skeletal Muscle Insulin Resistance in Obesity-Associated Type 2 Diabetes in Monkeys Is Linked to a Defect in Insulin Activation of Protein Kinase C-ζ/λ/ι

Mary L. Standaert, Heidi K. Ortmeyer, Mini P. Sajan, Yoshinori Kanoh, Gautam Bandyopadhyay, Barbara C. Hansen, Robert V. Farese

Diabetes 2002;51(10):2936–2943

https://doi.org/10.2337/diabetes.51.10.2936

Published: 01 October 2002

View article titled, Skeletal Muscle Insulin Resistance in Obesity-Associated Type 2 Diabetes in Monkeys Is Linked to a Defect in Insulin Activation of Protein Kinase C-ζ/λ/ι

Journal Articles

Chronic Activation of Protein Kinase C in Soleus Muscles and Other Tissues of Insulin-Resistant Type II diabetic Goto-Kakizaki (GK), Obese/Aged, and Obese/Zucker Rats: A Mechanism For Inhibiting Glycogen Synthesis

Antoine Avignon, Kouji Yamada, Xiaoping Zhou, Barbara Spencer, Osvaldo Cardona, Shereen Saba-Siddique, Lamar Galloway, Mary L Standaert, Robert V Farese

Diabetes 1996;45(10):1396–1404

https://doi.org/10.2337/diab.45.10.1396

Published: 01 October 1996

View article titled, Chronic Activation of Protein Kinase C in Soleus Muscles and Other Tissues of Insulin-Resistant Type II diabetic Goto-Kakizaki (GK), Obese/Aged, and Obese/Zucker Rats: A Mechanism For Inhibiting Glycogen Synthesis

Journal Articles

Downregulation of Protein Kinase C and Insulin-Stimulated 2-Deoxyglucose Uptake in Rat Adipocytes by Phorbol Esters, Glucose, and Insulin

Tatsuo Ishizuka, Denise R Cooper, Thomas Arnold, Herman Hernandez, Robert V Farese

Diabetes 1991;40(10):1274–1281

https://doi.org/10.2337/diab.40.10.1274

Published: 01 October 1991

View article titled, Downregulation of Protein Kinase C and Insulin-Stimulated 2-Deoxyglucose Uptake in Rat Adipocytes by Phorbol Esters, Glucose, and Insulin

Journal Articles

Sulfonylurea-Stimulated Glucose Transport Association With Diacylglycerollike Activation of Protein Kinase C in BC³H1 Myocytes

Denise R Cooper, Maria C Vila, James E Watson, Govindan Nair, Robert J Pollet, Mary Standaert, Robert V Farese

Diabetes 1990;39(11):1399–1407

https://doi.org/10.2337/diab.39.11.1399

Published: 01 November 1990

View article titled, Sulfonylurea-Stimulated Glucose Transport Association With Diacylglycerollike Activation of Protein Kinase C in BC3H1 Myocytes

Journal Articles

Effects of Insulin on Diacylglycerol–Protein Kinase C Signaling in Rat Diaphragm and Soleus Muscles and Relationship to Glucose Transport

Tatsuo Ishizuka, Denise R Cooper, Herman Hernandez, Donna Buckley, Mary Standaert, Robert V Farese

Diabetes 1990;39(2):181–190

https://doi.org/10.2337/diab.39.2.181

Published: 01 February 1990

View article titled, Effects of Insulin on Diacylglycerol–Protein Kinase C Signaling in Rat Diaphragm and Soleus Muscles and Relationship to Glucose Transport

Journal Articles

The Mechanism of Action of Insulin on Phospholipid Metabolism in Rat Adipose Tissue: Requirement for Protein Synthesis and a Carbohydrate Source, and Relationship to Activation of Pyruvate Dehydrogenase

Robert V Farese, Robert V Farese, Jr, Mohammad Ayub Sabir, Ronald E Larson, Walter L Trudeau, III

Diabetes 1984;33(7):648–655

https://doi.org/10.2337/diab.33.7.648

Published: 01 July 1984

View article titled, The Mechanism of Action of Insulin on Phospholipid Metabolism in Rat Adipose Tissue: Requirement for Protein Synthesis and a Carbohydrate Source, and Relationship to Activation of Pyruvate Dehydrogenase

Journal Articles

Insulin and Its Secretagogues Activate Ca²⁺-dependent Phosphatidylinositol Breakdown and Amylase Secretion in Rat Pancreas In Vitro

Robert V Farese, Ronald E Larson, Mohammad A Sabir

Diabetes 1981;30(5):396–401

https://doi.org/10.2337/diab.30.5.396

Published: 01 May 1981

View article titled, Insulin and Its Secretagogues Activate Ca2+-dependent Phosphatidylinositol Breakdown and Amylase Secretion in Rat Pancreas In Vitro

NARROW

Deletion of Protein Kinase C λ in POMC Neurons Predisposes to Diet-Induced Obesity

Brain Insulin Signaling Is Increased in Insulin-Resistant States and Decreases in FOXOs and PGC-1α and Increases in Aβ_1–40/42 and Phospho-Tau May Abet Alzheimer Development

Akt-Dependent Phosphorylation of Hepatic FoxO1 Is Compartmentalized on a WD40/ProF Scaffold and Is Selectively Inhibited by aPKC in Early Phases of Diet-Induced Obesity

Role of Adipocyte-Derived Factors in Enhancing Insulin Signaling in Skeletal Muscle and White Adipose Tissue of Mice Lacking Acyl CoA:Diacylglycerol Acyltransferase 1

Activation of Protein Kinase C-ζ by Insulin and Phosphatidylinositol-3,4,5-(PO₄)₃ Is Defective in Muscle in Type 2 Diabetes and Impaired Glucose Tolerance: Amelioration by Rosiglitazone and Exercise

Dissociation of Obesity and Impaired Glucose Disposal in Mice Overexpressing Acyl Coenzyme A:Diacylglycerol Acyltransferase 1 in White Adipose Tissue

Skeletal Muscle Insulin Resistance in Obesity-Associated Type 2 Diabetes in Monkeys Is Linked to a Defect in Insulin Activation of Protein Kinase C-ζ/λ/ι

Chronic Activation of Protein Kinase C in Soleus Muscles and Other Tissues of Insulin-Resistant Type II diabetic Goto-Kakizaki (GK), Obese/Aged, and Obese/Zucker Rats: A Mechanism For Inhibiting Glycogen Synthesis

Downregulation of Protein Kinase C and Insulin-Stimulated 2-Deoxyglucose Uptake in Rat Adipocytes by Phorbol Esters, Glucose, and Insulin

Sulfonylurea-Stimulated Glucose Transport Association With Diacylglycerollike Activation of Protein Kinase C in BC³H1 Myocytes

Effects of Insulin on Diacylglycerol–Protein Kinase C Signaling in Rat Diaphragm and Soleus Muscles and Relationship to Glucose Transport

The Mechanism of Action of Insulin on Phospholipid Metabolism in Rat Adipose Tissue: Requirement for Protein Synthesis and a Carbohydrate Source, and Relationship to Activation of Pyruvate Dehydrogenase

Insulin and Its Secretagogues Activate Ca²⁺-dependent Phosphatidylinositol Breakdown and Amylase Secretion in Rat Pancreas In Vitro

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