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Roelof A.J. Smit
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Journal Articles

The association between low sex hormone binding globulin and increased risk of type 2 diabetes is mediated by increased visceral and liver fat: results from observational and Mendelian randomization analyses

Theresa A. Stangl, MD, Chantal M. Wiepjes, MD, PhD, Roelof A.J. Smit, MD, PhD, Astrid van Hylckama Vlieg, PhD, Hildo. J. Lamb, MD, PhD, Jeroen H.P.M. van der Velde, PhD, Esther Winters van Eekelen, PhD, Sebastiaan C. Boone, MD, Martijn C.G.J. Brouwers, MD, PhD, Frits R. Rosendaal, MD, PhD, Martin den Heijer, MD, PhD, Annemieke C. Heijboer, MD, PhD, Renée de Mutsert, PhD
Journal: Diabetes
Diabetes db230982
https://doi.org/10.2337/db23-0982
Published: 06 August 2024
View article titled, The association between low sex hormone binding globulin and increased risk of type 2 diabetes is mediated by increased visceral and liver fat: results from observational and Mendelian randomization analyses
Open the PDF for The association between low sex hormone binding globulin and increased risk of type 2 diabetes is mediated by increased visceral and liver fat: results from observational and Mendelian randomization analyses in another window
Meeting Abstracts

1273-P: The Interplay between Polygenic and Rare HNF1A Variant Risk in Type 2 Diabetes

LAUREN STALBOW, MICHAEL H. PREUSS, NATHALIE CHAMI, ROELOF A.J. SMIT, RUTH J. LOOS
Journal: Diabetes
Diabetes 2022;71(Supplement_1):1273-P
https://doi.org/10.2337/db22-1273-P
Published: 01 June 2022
View article titled, 1273-P: The Interplay between Polygenic and Rare HNF1A Variant Risk in Type 2 Diabetes
Journal Articles

Stratification of Type 2 Diabetes by Age of Diagnosis in the UK Biobank Reveals Subgroup-Specific Genetic Associations and Causal Risk Profiles

Raymond Noordam, Kristi Läll, Roelof A.J. Smit, Triin Laisk, Andres Metspalu, Tõnu Esko, Lili Milani, Ruth J.F. Loos, Reedik Mägi, Ko Willems van Dijk, Diana van Heemst, Estonian Biobank Research Team, Andres Metspalu, Tõnu Esko, Lili Milani
Journal: Diabetes
Diabetes 2021;70(8):1816–1825
https://doi.org/10.2337/db20-0602
Published: 10 May 2021
View article titled, Stratification of Type 2 Diabetes by Age of Diagnosis in the UK Biobank Reveals Subgroup-Specific Genetic Associations and Causal Risk Profiles
Open the PDF for Stratification of Type 2 Diabetes by Age of Diagnosis in the UK Biobank Reveals Subgroup-Specific Genetic Associations and Causal Risk Profiles in another window
Journal Articles

Genetic Evidence for a Link Between Favorable Adiposity and Lower Risk of Type 2 Diabetes, Hypertension, and Heart Disease

Hanieh Yaghootkar, Luca A. Lotta, Jessica Tyrrell, Roelof A.J. Smit, Sam E. Jones, Louise Donnelly, Robin Beaumont, Archie Campbell, Marcus A. Tuke, Caroline Hayward, Katherine S. Ruth, Sandosh Padmanabhan, J. Wouter Jukema, Colin C. Palmer, Andrew Hattersley, Rachel M. Freathy, Claudia Langenberg, Nicholas J. Wareham, Andrew R. Wood, Anna Murray, Michael N. Weedon, Naveed Sattar, Ewan Pearson, Robert A. Scott, Timothy M. Frayling
Journal: Diabetes
Diabetes 2016;65(8):2448–2460
https://doi.org/10.2337/db15-1671
Published: 26 April 2016
View article titled, Genetic Evidence for a Link Between Favorable Adiposity and Lower Risk of Type 2 Diabetes, Hypertension, and Heart Disease
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Includes: Supplementary data