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Roger H. Unger
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Meeting Abstracts

Fasting-Induced Changes in Glucagon Secretion Are Dysregulated in Obesity

JENNIFER H. STERN, GORDON I. SMITH, ROGER H. UNGER, SAMUEL KLEIN, PHILIPP E. SCHERER
Journal: Diabetes
Diabetes 2018;67(Supplement_1):271-LB
https://doi.org/10.2337/db18-271-LB
Published: 01 July 2018
View article titled, Fasting-Induced Changes in Glucagon Secretion Are Dysregulated in Obesity
Journal Articles

Hypoglycemic Effect of Combined Ghrelin and Glucagon Receptor Blockade

Bharath K. Mani, Aki Uchida, Young Lee, Sherri Osborne-Lawrence, Maureen J. Charron, Roger H. Unger, Eric D. Berglund, Jeffrey M. Zigman
Journal: Diabetes
Diabetes 2017;66(7):1847–1857
https://doi.org/10.2337/db16-1303
Published: 09 May 2017
View article titled, Hypoglycemic Effect of Combined Ghrelin and Glucagon Receptor Blockade
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Includes: Supplementary data
Journal Articles

MitoNEET-Parkin Effects in Pancreatic α- and β-Cells, Cellular Survival, and Intrainsular Cross Talk

Christine M. Kusminski, Shiuhwei Chen, Risheng Ye, Kai Sun, Qiong A. Wang, Stephen B. Spurgin, Phillip E. Sanders, Joseph T. Brozinick, Werner J. Geldenhuys, Wen-hong Li, Roger H. Unger, Philipp E. Scherer
Journal: Diabetes
Diabetes 2016;65(6):1534–1555
https://doi.org/10.2337/db15-1323
Published: 08 March 2016
View article titled, MitoNEET-Parkin Effects in Pancreatic α- and β-Cells, Cellular Survival, and Intrainsular Cross Talk
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Includes: Supplementary data
Journal Articles

Role of Fibroblast Growth Factor 21 in Biology of Glucagon

Eric D. Berglund, Roger H. Unger
Journal: Diabetes
Diabetes 2013;62(5):1376
https://doi.org/10.2337/db12-1840
Published: 16 April 2013
View article titled, Role of Fibroblast Growth Factor 21 in Biology of Glucagon
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Journal Articles

Glucagon Receptor Knockout Prevents Insulin-Deficient Type 1 Diabetes in Mice

Young Lee, May-Yun Wang, Xiu Quan Du, Maureen J. Charron, Roger H. Unger
Journal: Diabetes
Diabetes 2011;60(2):391–397
https://doi.org/10.2337/db10-0426
Published: 21 January 2011
View article titled, Glucagon Receptor Knockout Prevents Insulin-Deficient Type 1 Diabetes in Mice
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Includes: Supplementary data
Journal Articles

Metabolic Mechanisms of Failure of Intraportally Transplanted Pancreatic β-Cells in Rats: Role of Lipotoxicity and Prevention by Leptin

Young Lee, Mariella Ravazzola, Byung-Hyun Park, Yuriy K. Bashmakov, Lelio Orci, Roger H. Unger
Journal: Diabetes
Diabetes 2007;56(9):2295–2301
https://doi.org/10.2337/db07-0460
Published: 01 September 2007
View article titled, Metabolic Mechanisms of Failure of Intraportally Transplanted Pancreatic β-Cells in Rats: <subtitle>Role of Lipotoxicity and Prevention by Leptin</subtitle>
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Journal Articles

β-Cell Function in Normal Rats Made Chronically Hyperleptinemic by Adenovirus-Leptin Gene Therapy

Kazunori Koyama, Guoxun Chen, May-Yun Wang, Young Lee, Michio Shimabukuro, Christopher B Newgard, Roger H Unger
Journal: Diabetes
Diabetes 1997;46(8):1276–1280
https://doi.org/10.2337/diab.46.8.1276
Published: 01 August 1997
View article titled, β-Cell Function in Normal Rats Made Chronically Hyperleptinemic by Adenovirus-Leptin Gene Therapy
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Journal Articles

Increased Lipogenic Capacity of the Islets of Obese Rats: A Role in the Pathogenesis of NIDDM

Young Lee, Hiroshi Hiros, Yan-Ting Zhou, Victoria Esser, J Denis McGarry, Roger H Unger
Journal: Diabetes
Diabetes 1997;46(3):408–413
https://doi.org/10.2337/diab.46.3.408
Published: 01 March 1997
View article titled, Increased Lipogenic Capacity of the Islets of Obese Rats: A Role in the Pathogenesis of NIDDM
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Journal Articles

Lipotoxicity in the Pathogenesis of Obesity-Dependent NIDDM: Genetic and Clinical Implications

Roger H Unger
Journal: Diabetes
Diabetes 1995;44(8):863–870
https://doi.org/10.2337/diab.44.8.863
Published: 01 August 1995
View article titled, Lipotoxicity in the Pathogenesis of Obesity-Dependent NIDDM: Genetic and Clinical Implications
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Journal Articles

More Direct Evidence for a Malonyl-CoA–Carnitine Palmitoyltransferase I Interaction as a Key Event in Pancreatic β-Cell Signaling

Songyvan Chen, Atsushi Ogawa, Makoto Ohneda, Roger H Unger, Daniel W Foster, J Denis McGarry
Journal: Diabetes
Diabetes 1994;43(7):878–883
https://doi.org/10.2337/diab.43.7.878
Published: 01 July 1994
View article titled, More Direct Evidence for a Malonyl-CoA–Carnitine Palmitoyltransferase I Interaction as a Key Event in Pancreatic β-Cell Signaling
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Journal Articles

GLUT2 Expression and Function in β-cells of GK rats with NIDDM: Dissociation Between Reductions in Glucose Transport and Glucose-Stimulated Insulin Secretion

Makoto Ohneda, John H Johnson, Lindsey R Inman, Ling Chen, Ken-Ichi Suzuki, Yoshio Goto, Tausif Alam, Mariella Ravazzola, Lelio Orci, Roger H Unger
Journal: Diabetes
Diabetes 1993;42(7):1065–1072
https://doi.org/10.2337/diab.42.7.1065
Published: 01 July 1993
View article titled, GLUT2 Expression and Function in β-cells of GK rats with NIDDM: Dissociation Between Reductions in Glucose Transport and Glucose-Stimulated Insulin Secretion
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Journal Articles

Comparison of Effects of High and Low Carbohydrate Diets on Plasma Lipoproteins and Insulin Sensitivity in Patients With Mild NIDDM

Abhimanyu Garg, Scott M Grundy, Roger H Unger
Journal: Diabetes
Diabetes 1992;41(10):1278–1285
https://doi.org/10.2337/diab.41.10.1278
Published: 01 October 1992
View article titled, Comparison of Effects of High and Low Carbohydrate Diets on Plasma Lipoproteins and Insulin Sensitivity in Patients With Mild NIDDM
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Journal Articles

Coordinate Regulation of Amylin and Insulin Expression in Response to Hypoglycemia and Fasting

Tausif Alam, Ling Chen, Atsushi Ogawa, Jonathan D Leffert, Roger H Unger, Kenneth L Luskey
Journal: Diabetes
Diabetes 1992;41(4):508–514
https://doi.org/10.2337/diab.41.4.508
Published: 01 April 1992
View article titled, Coordinate Regulation of Amylin and Insulin Expression in Response to Hypoglycemia and Fasting
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Journal Articles

Severe Diabetes Induced in Subtotally Depancreatized Dogs by Sustained Hyperglycemia

Toshinori Imamura, Michael Koffler, J Harold Helderman, Dale Prince, Richard Thirlby, Lindsey Inman, Roger H Unger
Journal: Diabetes
Diabetes 1988;37(5):600–609
https://doi.org/10.2337/diab.37.5.600
Published: 01 May 1988
View article titled, Severe Diabetes Induced in Subtotally Depancreatized Dogs by Sustained Hyperglycemia
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Journal Articles

Morphologic and Functional Changes in Sympathetic Nerve Relationships With Pancreatic α-Cells After Destruction of β-Cells in Rats

Makato Tominaga, Hiroshi Maruyama, M R Vasko, Dany Baetens, Lelio Orci, Roger H Unger
Journal: Diabetes
Diabetes 1987;36(3):365–373
https://doi.org/10.2337/diab.36.3.365
Published: 01 March 1987
View article titled, Morphologic and Functional Changes in Sympathetic Nerve Relationships With Pancreatic α-Cells After Destruction of β-Cells in Rats
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Journal Articles

Pancreatic Alpha Cell Autoantibodies and Glucagon Response to Arginine

William E Winter, Noel K Maclaren, William J Riley, Roger H Unger, Michel Neufeld, Pinar T Ozand
Journal: Diabetes
Diabetes 1984;33(5):435–437
https://doi.org/10.2337/diab.33.5.435
Published: 01 May 1984
View article titled, Pancreatic Alpha Cell Autoantibodies and Glucagon Response to Arginine
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Journal Articles

Normal Insulin Sensitivity of the Islets of Langerhans in Obese Subjects with Resistance to Its Glucoregulatory Actions

Iwar Klimes, Murugasu Nagulesparan, Barbara Vasquez, Hideki Hidaka, Roger H Unger
Journal: Diabetes
Diabetes 1984;33(4):305–310
https://doi.org/10.2337/diab.33.4.305
Published: 01 April 1984
View article titled, Normal Insulin Sensitivity of the Islets of Langerhans in Obese Subjects with Resistance to Its Glucoregulatory Actions
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Journal Articles

Secretin Inhibits Glucagon in the Isolated Perfused Dog Pancreas

Akitaka Hisatomi, Roger H Unger
Journal: Diabetes
Diabetes 1983;32(10):970–973
https://doi.org/10.2337/diab.32.10.970
Published: 01 October 1983
View article titled, Secretin Inhibits Glucagon in the Isolated Perfused Dog Pancreas
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Journal Articles

Insulin-Glucagon Relationships in the Defense Against Hypoglycemia

Roger H Unger
Journal: Diabetes
Diabetes 1983;32(6):575–583
https://doi.org/10.2337/diab.32.6.575
Published: 01 June 1983
View article titled, Insulin-Glucagon Relationships in the Defense Against Hypoglycemia
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Journal Articles

Quantitation of Endocrine Cell Content in the Pancreas of Nondiabetic and Diabetic Humans

Yolande Stefan, Lelio Orci, Francine Malaisse-Lagae, Alain Perrelet, Yogesh Patel, Roger H Unger
Journal: Diabetes
Diabetes 1982;31(8):694–700
https://doi.org/10.2337/diab.31.8.694
Published: 01 August 1982
View article titled, Quantitation of Endocrine Cell Content in the Pancreas of Nondiabetic and Diabetic Humans
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