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Journal Articles

The Whole Human Pancreas: An Understudied Organ in Diabetes

Roy Taylor
Journal: Diabetes
Diabetes 2024;73(7):1043–1045
https://doi.org/10.2337/dbi23-0021
Published: 20 June 2024
View article titled, The Whole Human Pancreas: An Understudied Organ in Diabetes
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Meeting Abstracts

257-OR: ADA Presidents' Select Abstract: The Effect of a Reduced-Energy Diet upon Maternal Weight and Pregnancy Outcomes in Women with Gestational Diabetes—The DiGest Trial

LAURA C. KUSINSKI, DANIELLE JONES, NOORIA ATTA, ELIZABETH TURNER, LINDA M. OUDE GRIEP, KIRSTEN L. RENNIE, EMANUELLA DE LUCIA ROLFE, STEPHEN SHARP, HELEN R. MURPHY, ROY TAYLOR, CLAIRE L. MEEK
Journal: Diabetes
Diabetes 2024;73(Supplement_1):257-OR
https://doi.org/10.2337/db24-257-OR
Published: 14 June 2024
View article titled, 257-OR: ADA Presidents' Select Abstract: The Effect of a Reduced-Energy Diet upon Maternal Weight and Pregnancy Outcomes in Women with Gestational Diabetes—The DiGest Trial
Meeting Abstracts

65-OR: Continuous Glucose Monitoring Metrics and Suboptimal Pregnancy Outcomes in Women with Gestational Diabetes—Secondary Analysis of the DiGest Trial

LAURA C. KUSINSKI, DANIELLE JONES, NOORIA ATTA, ELIZABETH TURNER, LINDA M. OUDE GRIEP, KIRSTEN L. RENNIE, EMANUELLA DE LUCIA ROLFE, HELEN R. MURPHY, ROY TAYLOR, CLAIRE L. MEEK
Journal: Diabetes
Diabetes 2024;73(Supplement_1):65-OR
https://doi.org/10.2337/db24-65-OR
Published: 14 June 2024
View article titled, 65-OR: Continuous Glucose Monitoring Metrics and Suboptimal Pregnancy Outcomes in Women with Gestational Diabetes—Secondary Analysis of the DiGest Trial
Meeting Abstracts

218-LB: Remission of Type 2 Diabetes after Weight Loss in "Normal" Weight People—The ReTUNE Study

ROY TAYLOR, KEATON M. IRVINE, ALISON C. BARNES, TARA L. KELLY, LUCY G. CLARK, KIEREN G. HOLLINGSWORTH, AHMAD AL-MRABEH, RURY R. HOLMAN, DAVIDE ROMERES, CLAUDIO COBELLI
Journal: Diabetes
Diabetes 2022;71(Supplement_1):218-LB
https://doi.org/10.2337/db22-218-LB
Published: 01 June 2022
View article titled, 218-LB: Remission of Type 2 Diabetes after Weight Loss in "Normal" Weight People—The ReTUNE Study
Meeting Abstracts

1184-P: Return to Normal Glucose Control by Weight Loss in Nonobese People with Type 2 Diabetes: The ReTUNE Study

AHMAD AL-MRABEH, ALISON C. BARNES, KEATON M. IRVINE, TARA L. KELLY, KIEREN G. HOLLINGSWORTH, DAVIDE ROMERES, CLAUDIO COBELLI, ROY TAYLOR
Journal: Diabetes
Diabetes 2021;70(Supplement_1):1184-P
https://doi.org/10.2337/db21-1184-P
Published: 01 June 2021
View article titled, 1184-P: Return to Normal Glucose Control by Weight Loss in Nonobese People with Type 2 Diabetes: The ReTUNE Study
Meeting Abstracts

1781-P: Remission of Type 2 Diabetes over 2 Years Normalizes Morphology of the Whole Pancreas

ROY TAYLOR, SVIATLANA V. ZHYZHNEUSKAYA, CARL PETERS, ALISON C. BARNES, KIEREN G. HOLLINGSWORTH, NAVEED SATTAR, MICHAEL E. LEAN, AHMAD AL-MRABEH
Journal: Diabetes
Diabetes 2020;69(Supplement_1):1781-P
https://doi.org/10.2337/db20-1781-P
Published: 01 June 2020
View article titled, 1781-P: Remission of Type 2 Diabetes over 2 Years Normalizes Morphology of the Whole Pancreas
Meeting Abstracts

312-OR: Gender-Specific Effects on Hepatic Fat Metabolism in Type 2 Diabetes before and after Remission

AHMAD AL-MRABEH, SHADEN MELHEM, SVIATLANA V. ZHYZHNEUSKAYA, CARL PETERS, ALISON C. BARNES, KIEREN G. HOLLINGSWORTH, NAVEED SATTAR, MICHAEL E. LEAN, ROY TAYLOR
Journal: Diabetes
Diabetes 2020;69(Supplement_1):312-OR
https://doi.org/10.2337/db20-312-OR
Published: 01 June 2020
View article titled, 312-OR: Gender-Specific Effects on Hepatic Fat Metabolism in Type 2 Diabetes before and after Remission
Meeting Abstracts

1844-P: Long-Term Remission of Type 2 Diabetes after Weight Loss Requires Effective Clearance of Hepatic VLDL-TG and Maintenance of Low Intrapancreatic Fat

AHMAD AL-MRABEH, SVIATLANA V. ZHYZHNEUSKAYA, ALISON C. BARNES, KIEREN G. HOLLINGSWORTH, NAVEED SATTAR, MICHAEL E. LEAN, ROY TAYLOR
Journal: Diabetes
Diabetes 2019;68(Supplement_1):1844-P
https://doi.org/10.2337/db19-1844-P
Published: 01 June 2019
View article titled, 1844-P: Long-Term Remission of Type 2 Diabetes after Weight Loss Requires Effective Clearance of Hepatic VLDL-TG and Maintenance of Low Intrapancreatic Fat
Meeting Abstracts

66-OR: Remission of Type 2 Diabetes for Two Years Is Associated with Full Recovery of Beta-Cell Functional Mass in the Diabetes Remission Clinical Trial (DiRECT)

SVIATLANA V. ZHYZHNEUSKAYA, AHMAD AL-MRABEH, ALISON C. BARNES, BENJAMIN ARIBISALA, KIEREN G. HOLLINGSWORTH, HELEN PILKINGTON, NAVEED SATTAR, MICHAEL E. LEAN, ROY TAYLOR
Journal: Diabetes
Diabetes 2019;68(Supplement_1):66-OR
https://doi.org/10.2337/db19-66-OR
Published: 01 June 2019
View article titled, 66-OR: Remission of Type 2 Diabetes for Two Years Is Associated with Full Recovery of Beta-Cell Functional Mass in the Diabetes Remission Clinical Trial (DiRECT)
Meeting Abstracts

Pathophysiology of Remission in Type 2 Diabetes—The Diabetes Remission Clinical Trial (DiRECT)

ROY TAYLOR, AHMAD AL-MRABEH, SVIATLANA V. ZHYZHNEUSKAYA, CARL PETERS, ALISON C. BARNES, BENJAMIN ARIBISALA, KIEREN G. HOLLINGSWORTH, NAVEED SATTAR, MICHAEL E. LEAN
Journal: Diabetes
Diabetes 2018;67(Supplement_1):40-OR
https://doi.org/10.2337/db18-40-OR
Published: 01 July 2018
View article titled, Pathophysiology of Remission in Type 2 Diabetes—The Diabetes Remission Clinical Trial (DiRECT)
Meeting Abstracts

Diabetes Remission Clinical Trial (DiRECT)—Changes in Hepatic VLDL1-TG Production and Intrapancreatic Fat during Weight Maintenance Phase

AHMAD AL-MRABEH, SVIATLANA V. ZHYZHNEUSKAYA, CARL PETERS, ALISON C. BARNES, BENJAMIN ARIBISALA, KIEREN G. HOLLINGSWORTH, NAVEED SATTAR, MICHAEL E. LEAN, ROY TAYLOR
Journal: Diabetes
Diabetes 2018;67(Supplement_1):42-OR
https://doi.org/10.2337/db18-42-OR
Published: 01 July 2018
View article titled, Diabetes Remission Clinical Trial (DiRECT)—Changes in Hepatic VLDL1-TG Production and Intrapancreatic Fat during Weight Maintenance Phase
Meeting Abstracts

Diabetes Remission Clinical Trial (DiRECT)—Plasma Liver Function Tests Reflect Change in Liver Fat Content in Early Type 2 Diabetes

SVIATLANA V. ZHYZHNEUSKAYA, AHMAD AL-MRABEH, CARL PETERS, ALISON C. BARNES, KIEREN G. HOLLINGSWORTH, HELEN PILKINGTON, PAUL WELSH, NAVEED SATTAR, MICHAEL E. LEAN, ROY TAYLOR
Journal: Diabetes
Diabetes 2018;67(Supplement_1):1834-P
https://doi.org/10.2337/db18-1834-P
Published: 01 July 2018
View article titled, Diabetes Remission Clinical Trial (DiRECT)—Plasma Liver Function Tests Reflect Change in Liver Fat Content in Early Type 2 Diabetes
Meeting Abstracts

Baseline Predictors and Influence of Early Weight Loss during an Intensive Weight Management Programme on Remission of Type 2 Diabetes after 12 Months—Post-Hoc Analysis of the Diabetes Remission Clinical Trial (DiRECT)

MICHAEL E.J. LEAN, WILMA S. LESLIE, NAVEED SATTAR, GEORGE THOM, ELIZABETH L. MCCOMBIE, NAOMI T. BROSNAHAN, ALISON C. BARNES, ROY TAYLOR, ALEX MCCONNACHIE, FOR THE DIRECT STUDY TEAM
Journal: Diabetes
Diabetes 2018;67(Supplement_1):291-OR
https://doi.org/10.2337/db18-291-OR
Published: 01 July 2018
View article titled, Baseline Predictors and Influence of Early Weight Loss during an Intensive Weight Management Programme on Remission of Type 2 Diabetes after 12 Months—Post-Hoc Analysis of the Diabetes Remission Clinical Trial (DiRECT)
Journal Articles

Insulin Resistance and Type 2 Diabetes

Roy Taylor
Journal: Diabetes
Diabetes 2012;61(4):778–779
https://doi.org/10.2337/db12-0073
Published: 14 March 2012
View article titled, Insulin Resistance and Type 2 Diabetes
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Journal Articles

Pioglitazone Decreases Fasting and Postprandial Endogenous Glucose Production in Proportion to Decrease in Hepatic Triglyceride Content

Balasubramanian Ravikumar, Jean Gerrard, Chiara Dalla Man, Michael J. Firbank, Annette Lane, Philip T. English, Claudio Cobelli, Roy Taylor
Journal: Diabetes
Diabetes 2008;57(9):2288–2295
https://doi.org/10.2337/db07-1828
Published: 01 September 2008
View article titled, Pioglitazone Decreases Fasting and Postprandial Endogenous Glucose Production in Proportion to Decrease in Hepatic Triglyceride Content
Open the PDF for Pioglitazone Decreases Fasting and Postprandial Endogenous Glucose Production in Proportion to Decrease in Hepatic Triglyceride Content in another window
Journal Articles

Effects of Tumor Necrosis Factor-α on Insulin Action in Cultured Human Muscle Cells

Reza Halse, Samantha L. Pearson, James G. McCormack, Stephen J. Yeaman, Roy Taylor
Journal: Diabetes
Diabetes 2001;50(5):1102–1109
https://doi.org/10.2337/diabetes.50.5.1102
Published: 01 May 2001
View article titled, Effects of Tumor Necrosis Factor-α on Insulin Action in Cultured Human Muscle Cells
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Journal Articles

Effects of an Engineered Human Anti–TNF-α Antibody (CDP571) on Insulin Sensitivity and Glycemic Control in Patients With NIDDM

Francis Ofei, Steve Hurel, José Newkirk, Mark Sopwith, Roy Taylor
Journal: Diabetes
Diabetes 1996;45(7):881–885
https://doi.org/10.2337/diab.45.7.881
Published: 01 July 1996
View article titled, Effects of an Engineered Human Anti–TNF-α Antibody (CDP571) on Insulin Sensitivity and Glycemic Control in Patients With NIDDM
Open the PDF for Effects of an Engineered Human Anti–TNF-α Antibody (CDP571) on Insulin Sensitivity and Glycemic Control in Patients With NIDDM in another window
Journal Articles

Abnormal Activation of Glycogen Synthesis in Fibroblasts from NIDDM Subjects: Evidence for an Abnormality Specific to Glucose Metabolism

Ann M Wells, Iain C Sutcliffe, Andrew B Johnson, Roy Taylor
Journal: Diabetes
Diabetes 1993;42(4):583–589
https://doi.org/10.2337/diab.42.4.583
Published: 01 April 1993
View article titled, Abnormal Activation of Glycogen Synthesis in Fibroblasts from NIDDM Subjects: Evidence for an Abnormality Specific to Glucose Metabolism
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