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Meeting Abstracts

735-P: Direct Anti-Inflammatory and Antifibrotic Effects of a Novel Long-Acting Glucagon/GIP/GLP-1 Triple Agonist, HM15211, in Thioacetamide-Induced Mouse Model of Liver Injury and Fibrosis

JUNG KUK KIM, JONG SUK LEE, YOHAN KIM, SEON MYEONG LEE, HYUNJOO KWON, EUNJIN PARK, JAEHYUK CHOI, SUNGMIN BAE, DAEJIN KIM, SANG HYUN LEE, IN YOUNG CHOI
Journal: Diabetes
Diabetes 2022;71(Supplement_1):735-P
DOI: https://doi.org/10.2337/db22-735-P
Published: 01 June 2022
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Meeting Abstracts

754-P: Antifibrotic Potential of a Novel Long-Acting Glucagon/GIP/GLP-1 Triple Agonist (HM15211) in Preclinical Models of IPF

SEON MYEONG LEE, JEONG A. KIM, JONG SUK LEE, JUNG KUK KIM, YOUNG-HWAN BAN, JONGSOO LEE, SUNGMIN BAE, DAEJIN KIM, SANG HYUN LEE, IN YOUNG CHOI
Journal: Diabetes
Diabetes 2022;71(Supplement_1):754-P
DOI: https://doi.org/10.2337/db22-754-P
Published: 01 June 2022
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Meeting Abstracts

655-P: Multitarget Engagement Effect of a Novel Long-Acting Glucagon/GIP/GLP-1 Triple Agonist (HM15211) in Animal Model of NASH

JUNG KUK KIM, JONG SUK LEE, HYUNJOO KWON, EUNJIN PARK, JONGSOO LEE, SUNGMIN BAE, SANG HYUN LEE, IN YOUNG CHOI
Journal: Diabetes
Diabetes 2021;70(Supplement_1):655-P
DOI: https://doi.org/10.2337/db21-655-P
Published: 01 June 2021
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Meeting Abstracts

656-P: Antifibrotic Potential of a Novel Long-Acting Glucagon/GIP/GLP-1 Triple Agonist (HM15211) in Preclinical Models of Fibrosis

JUNG KUK KIM, JONG SUK LEE, SEON MYEONG LEE, HYUNJOO KWON, JAEHYUK CHOI, EUNJIN PARK, SUNGMIN BAE, DAEJIN KIM, YOUNG HOON KIM, IN YOUNG CHOI
Journal: Diabetes
Diabetes 2021;70(Supplement_1):656-P
DOI: https://doi.org/10.2337/db21-656-P
Published: 01 June 2021
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Meeting Abstracts

657-P: Potential Effect of a Novel Combination of GLP-1RA (efpeglenatide) and Long-Acting Glucagon Analog (HM15136) in Animal Models of Metabolic Disorders

JONG SUK LEE, JUNG KUK KIM, SEON MYEONG LEE, JAEHYUK CHOI, EUNJIN PARK, DAEJIN KIM, SUNGMIN BAE, SANG HYUN LEE, IN YOUNG CHOI
Journal: Diabetes
Diabetes 2021;70(Supplement_1):657-P
DOI: https://doi.org/10.2337/db21-657-P
Published: 01 June 2021
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Meeting Abstracts

1830-P: Therapeutic Effect of a Novel Long-Acting GLP-1/GIP/Glucagon Triple Agonist (HM15211) in CDHFD-Induced NASH and Fibrosis Mice

JAEHYUK CHOI, JUNG KUK KIM, SEON MYEONG LEE, HYUNJOO KWON, JONGSOO LEE, SUNGMIN BAE, DAEJIN KIM, IN YOUNG CHOI
Journal: Diabetes
Diabetes 2020;69(Supplement_1):1830-P
DOI: https://doi.org/10.2337/db20-1830-P
Published: 01 June 2020
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Meeting Abstracts

1804-P: HM15211, a Novel Long-Acting GLP-1/GIP/Glucagon Triple Agonist, Exhibits Anti-inflammatory and Fibrotic Effects in AMLN/TAA–Induced Liver Inflammation and Fibrosis Mice

JUNG KUK KIM, JONG SUK LEE, EUNJIN PARK, JONGSOO LEE, SUNGMIN BAE, DAEJIN KIM, IN YOUNG CHOI
Journal: Diabetes
Diabetes 2020;69(Supplement_1):1804-P
DOI: https://doi.org/10.2337/db20-1804-P
Published: 01 June 2020
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Meeting Abstracts

1803-P: Antifibrotic Effect of a Novel Long-Acting GLP-1/GIP/Glucagon Triple Agonist (HM15211) in BDL-Induced Liver Fibrosis Mice

JUNG KUK KIM, JONG SUK LEE, HYUNJOO KWON, JONGSOO LEE, DAEJIN KIM, SUNGMIN BAE, SANG HYUN LEE, IN YOUNG CHOI
Journal: Diabetes
Diabetes 2020;69(Supplement_1):1803-P
DOI: https://doi.org/10.2337/db20-1803-P
Published: 01 June 2020
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Meeting Abstracts

1926-P: Potent Weight Loss Mechanism of a Novel Long-Acting Glucagon Analog, HM15136, in Animal Models of Obesity

JONG SUK LEE, SEON MYEONG LEE, JUNG KUK KIM, JONGSOO LEE, SANG DON LEE, SUNGMIN BAE, DAEJIN KIM, IN YOUNG CHOI
Journal: Diabetes
Diabetes 2020;69(Supplement_1):1926-P
DOI: https://doi.org/10.2337/db20-1926-P
Published: 01 June 2020
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Meeting Abstracts

1925-P: Beneficial Effects of a Novel Long-Acting Glucagon Analog, HM15136, on Obesity and Obesity-Related Metabolic Disorders in Animal Models

JONG SUK LEE, SEON MYEONG LEE, JAEHYUK CHOI, EUNJIN PARK, JONGSOO LEE, SANG DON LEE, SUNGMIN BAE, DAEJIN KIM, IN YOUNG CHOI
Journal: Diabetes
Diabetes 2020;69(Supplement_1):1925-P
DOI: https://doi.org/10.2337/db20-1925-P
Published: 01 June 2020
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Meeting Abstracts

1810-P: Effect of HM15211, a Novel Long-Acting GLP-1/GIP/Glucagon Triple Agonist in the Neurodegenerative Disease Models

KIM WONKI, JEONG A. KIM, SANG HYUN LEE, SUNGMIN BAE, IN YOUNG CHOI, YOUNG HOON KIM
Journal: Diabetes
Diabetes 2019;68(Supplement_1):1810-P
DOI: https://doi.org/10.2337/db19-1810-P
Published: 01 June 2019
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Meeting Abstracts

109-LB: Potent Weight Loss Mechanism by a Novel Long-Acting Glucagon Analog, HM15136, in Animal Models

JONG SUK LEE, JUNG KUK KIM, JINYOUNG KIM, EUNJIN PARK, SANG HYUN LEE, SUNGMIN BAE, IN YOUNG CHOI
Journal: Diabetes
Diabetes 2019;68(Supplement_1):109-LB
DOI: https://doi.org/10.2337/db19-109-LB
Published: 01 June 2019
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