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Meeting Abstracts

166-OR: The Alpha–Catenin–Cholesterol Biosynthesis Axis Regulates Tight Junction Formation in Pancreatic Islets

WILMA TIXI, WILSON YEUNG, AMY CHIU, SANGEETA DHAWAN, BEN SHIH
Journal: Diabetes
Diabetes 2024;73(Supplement_1):166-OR
https://doi.org/10.2337/db24-166-OR
Published: 14 June 2024
View articletitled, 166-OR: The Alpha–Catenin–Cholesterol Biosynthesis Axis Regulates Tight Junction Formation in Pancreatic Islets
Meeting Abstracts

1724-P: DNA Damage Vulnerability of Immature Beta Cells

SNEHA S. VARGHESE, ALESSANDRO G. HERNANDEZ-DE LA PENA, SUPRIYO BHATTACHARYA, SANGEETA DHAWAN
Journal: Diabetes
Diabetes 2024;73(Supplement_1):1724-P
https://doi.org/10.2337/db24-1724-P
Published: 14 June 2024
View articletitled, 1724-P: DNA Damage Vulnerability of Immature Beta Cells
Meeting Abstracts

869-P: Gastrin Reduces Incidence of Type 1 Diabetes through Reducing Inflammation and Preserving ß-Cell Mass in Animal Model

LYNN N. MIAO, ANGEL S. GU, MOHAMED I. HUSSEINY, JEFFREY RAWSON, JACOB MARES, CHRIS ORR, SANGEETA DHAWAN, BEN SHIH, HSUN T. KU, FOUAD R. KANDEEL
Journal: Diabetes
Diabetes 2024;73(Supplement_1):869-P
https://doi.org/10.2337/db24-869-P
Published: 14 June 2024
View articletitled, 869-P: Gastrin Reduces Incidence of Type 1 Diabetes through Reducing Inflammation and Preserving ß-Cell Mass in Animal Model
Journal Articles

Erratum. DNA Methylation–Dependent Restriction of Tyrosine Hydroxylase Contributes to Pancreatic β-Cell Heterogeneity. Diabetes 2023;72:575–589

Nazia Parveen, Jean Kimi Wang, Supriyo Bhattacharya, Janielle Cuala, Mohan Singh Rajkumar, Alexandra E. Butler, Xiwei Wu, Hung-Ping Shih, Senta K. Georgia, Sangeeta Dhawan
Journal: Diabetes
Diabetes 2023;72(12):1882
https://doi.org/10.2337/db23-er12a
Published: 08 September 2023
View articletitled, Erratum. DNA Methylation–Dependent Restriction of Tyrosine Hydroxylase Contributes to Pancreatic β-Cell Heterogeneity. Diabetes 2023;72:575–589
Open the PDF for Erratum. DNA Methylation–Dependent Restriction of Tyrosine Hydroxylase Contributes to Pancreatic β-Cell Heterogeneity. Diabetes 2023;72:575–589 in another window
Meeting Abstracts

375-OR: Epigenetic Control of Beta-Cell Stress Response and Senescence

SNEHA S. VARGHESE, NAZIA PARVEEN, JEAN K. WANG, ALESSANDRO G. HERNANDEZ-DE LA PENA, SANGEETA DHAWAN
Journal: Diabetes
Diabetes 2023;72(Supplement_1):375-OR
https://doi.org/10.2337/db23-375-OR
Published: 20 June 2023
View articletitled, 375-OR: Epigenetic Control of Beta-Cell Stress Response and Senescence
Journal Articles

DNA Methylation–Dependent Restriction of Tyrosine Hydroxylase Contributes to Pancreatic β-Cell Heterogeneity

Nazia Parveen, Jean Kimi Wang, Supriyo Bhattacharya, Janielle Cuala, Mohan Singh Rajkumar, Alexandra E. Butler, Xiwei Wu, Hung-Ping Shih, Senta K. Georgia, Sangeeta Dhawan
Journal: Diabetes
Diabetes 2023;72(5):575–589
https://doi.org/10.2337/db22-0506
Published: 06 January 2023
View articletitled, DNA Methylation–Dependent Restriction of Tyrosine Hydroxylase Contributes to Pancreatic β-Cell Heterogeneity
Open the PDF for DNA Methylation–Dependent Restriction of Tyrosine Hydroxylase Contributes to Pancreatic β-Cell Heterogeneity in another window
Journal Articles

Yo-Yo Dieting: Mixed Messages for β-Cell Plasticity

Ke Ma, Sangeeta Dhawan
Journal: Diabetes
Diabetes 2022;71(11):2253–2255
https://doi.org/10.2337/dbi22-0024
Published: 13 October 2022
View articletitled, Yo-Yo Dieting: Mixed Messages for β-Cell Plasticity
Open the PDF for Yo-Yo Dieting: Mixed Messages for β-Cell Plasticity in another window
Journal Articles

The Yin and Yang of Modulating β-Cell DNA Damage Response and Functional Mass

Jason M. Spaeth, Sangeeta Dhawan
Journal: Diabetes
Diabetes 2022;71(8):1614–1616
https://doi.org/10.2337/dbi22-0010
Published: 21 August 2022
View articletitled, The Yin and Yang of Modulating β-Cell DNA Damage Response and Functional Mass
Open the PDF for The Yin and Yang of Modulating β-Cell DNA Damage Response and Functional Mass in another window
Meeting Abstracts

202-OR: Early De Novo DNA Methylation Patterning Regulates Adult Beta-Cell Function and Survival Programs

NAZIA PARVEEN, JEAN K. WANG, ALEXANDER P. HAM, SANGEETA DHAWAN
Journal: Diabetes
Diabetes 2022;71(Supplement_1):202-OR
https://doi.org/10.2337/db22-202-OR
Published: 01 June 2022
View articletitled, 202-OR: Early De Novo DNA Methylation Patterning Regulates Adult Beta-Cell Function and Survival Programs
Meeting Abstracts

174-OR: ADA Presidents’ Select Abstract: Epigenetic Regulation of Functional Beta-Cell Mass by Cohesin Smc3

JEAN K. WANG, APARAMITA PANDEY, ALEXANDER P. HAM, NAZIA PARVEEN, SANGEETA DHAWAN
Journal: Diabetes
Diabetes 2021;70(Supplement_1):174-OR
https://doi.org/10.2337/db21-174-OR
Published: 01 June 2021
View articletitled, 174-OR: ADA Presidents’ Select Abstract: Epigenetic Regulation of Functional Beta-Cell Mass by Cohesin Smc3
Journal Articles

Integrative Omics Analyses Reveal Epigenetic Memory in Diabetic Renal Cells Regulating Genes Associated With Kidney Dysfunction

Anita Bansal, Sreeram Balasubramanian, Sangeeta Dhawan, Amy Leung, Zhen Chen, Rama Natarajan
Journal: Diabetes
Diabetes 2020;69(11):2490–2502
https://doi.org/10.2337/db20-0382
Published: 03 August 2020
View articletitled, Integrative Omics Analyses Reveal Epigenetic Memory in Diabetic Renal Cells Regulating Genes Associated With Kidney Dysfunction
Open the PDF for Integrative Omics Analyses Reveal Epigenetic Memory in Diabetic Renal Cells Regulating Genes Associated With Kidney Dysfunction in another window
Meeting Abstracts

259-OR: Epigenetic Coregulation of Beta-Cell Function and Survival in Postnatal Life

SANGEETA DHAWAN, TATYANA GURLO, JEAN K. WANG
Journal: Diabetes
Diabetes 2020;69(Supplement_1):259-OR
https://doi.org/10.2337/db20-259-OR
Published: 01 June 2020
View articletitled, 259-OR: Epigenetic Coregulation of Beta-Cell Function and Survival in Postnatal Life
Meeting Abstracts

258-OR: DNA Methylation Regulates the Identity of Pancreatic Beta Cells

NAZIA PARVEEN, JEAN K. WANG, SANGEETA DHAWAN
Journal: Diabetes
Diabetes 2020;69(Supplement_1):258-OR
https://doi.org/10.2337/db20-258-OR
Published: 01 June 2020
View articletitled, 258-OR: DNA Methylation Regulates the Identity of Pancreatic Beta Cells
Journal Articles

Examining How the MAFB Transcription Factor Affects Islet β-Cell Function Postnatally

Holly A. Cyphert, Emily M. Walker, Yan Hang, Sangeeta Dhawan, Rachana Haliyur, Lauren Bonatakis, Dana Avrahami, Marcela Brissova, Klaus H. Kaestner, Anil Bhushan, Alvin C. Powers, Roland Stein
Journal: Diabetes
Diabetes 2019;68(2):337–348
https://doi.org/10.2337/db18-0903
Published: 13 November 2018
View articletitled, Examining How the MAFB Transcription Factor Affects Islet β-Cell Function Postnatally
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Includes: Supplementary data
Meeting Abstracts

DNA Hydroxymethylation Regulates Beta-Cell Maturation and Expansion

TATYANA GURLO, SENTA GEORGIA, SANGEETA DHAWAN
Journal: Diabetes
Diabetes 2018;67(Supplement_1):50-OR
https://doi.org/10.2337/db18-50-OR
Published: 01 July 2018
View articletitled, DNA Hydroxymethylation Regulates Beta-Cell Maturation and Expansion
Journal Articles

Postnatal Ontogenesis of the Islet Circadian Clock Plays a Contributory Role in β-Cell Maturation Process

Kuntol Rakshit, Jingyi Qian, Krutika Satish Gaonkar, Sangeeta Dhawan, Christopher S. Colwell, Aleksey V. Matveyenko
Journal: Diabetes
Diabetes 2018;67(5):911–922
https://doi.org/10.2337/db17-0850
Published: 02 March 2018
View articletitled, Postnatal Ontogenesis of the Islet Circadian Clock Plays a Contributory Role in β-Cell Maturation Process
Open the PDF for Postnatal Ontogenesis of the Islet Circadian Clock Plays a Contributory Role in β-Cell Maturation Process in another window
Includes: Supplementary data
Journal Articles

Inhibition of TGF-β Signaling Promotes Human Pancreatic β-Cell Replication

Sangeeta Dhawan, Ercument Dirice, Rohit N. Kulkarni, Anil Bhushan
Journal: Diabetes
Diabetes 2016;65(5):1208–1218
https://doi.org/10.2337/db15-1331
Published: 02 March 2016
View articletitled, Inhibition of TGF-β Signaling Promotes Human Pancreatic β-Cell Replication
Open the PDF for Inhibition of TGF-β Signaling Promotes Human Pancreatic β-Cell Replication in another window
Includes: Supplementary data
Journal Articles

β-Cell Identity in Type 2 Diabetes: Lost or Found?

Alexandra E. Butler, Sangeeta Dhawan
Journal: Diabetes
Diabetes 2015;64(8):2698–2700
https://doi.org/10.2337/db15-0550
Published: 16 July 2015
View articletitled, β-Cell Identity in Type 2 Diabetes: Lost or Found?
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Journal Articles

Age-Dependent Decline in β-Cell Proliferation Restricts the Capacity of β-Cell Regeneration in Mice

Shuen-Ing Tschen, Sangeeta Dhawan, Tatyana Gurlo, Anil Bhushan
Journal: Diabetes
Diabetes 2009;58(6):1312–1320
https://doi.org/10.2337/db08-1651
Published: 19 February 2009
View articletitled, Age-Dependent Decline in β-Cell Proliferation Restricts the Capacity of β-Cell Regeneration in Mice
Open the PDF for Age-Dependent Decline in β-Cell Proliferation Restricts the Capacity of β-Cell Regeneration in Mice in another window