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Journal Articles

An E115A Missense Variant in CERS2 Is Associated With Increased Sleeping Energy Expenditure and Hepatic Insulin Resistance in American Indians

Sascha Heinitz, Michael Traurig, Jonathan Krakoff, Philipp Rabe, Claudia Stäubert, Sayuko Kobes, Robert L. Hanson, Michael Stumvoll, Matthias Blüher, Clifton Bogardus, Leslie Baier, Paolo Piaggi
Journal: Diabetes
Diabetes 2024;73(8):1361–1371
https://doi.org/10.2337/db23-0690
Published: 22 May 2024
View articletitled, An E115A Missense Variant in CERS2 Is Associated With Increased Sleeping Energy Expenditure and Hepatic Insulin Resistance in American Indians
Open the PDF for An E115A Missense Variant in CERS2 Is Associated With Increased Sleeping Energy Expenditure and Hepatic Insulin Resistance in American Indians in another window
Meeting Abstracts

1476-P: Genetic Relationships between Puberty Onset and Type 2 Diabetes

MARIA J. RAMIREZ-LUZURIAGA, SAYUKO KOBES, LAUREN E. WEDEKIND, WEN-CHI HSUEH, LESLIE BAIER, ROBERT L. HANSON
Journal: Diabetes
Diabetes 2023;72(Supplement_1):1476-P
https://doi.org/10.2337/db23-1476-P
Published: 20 June 2023
View articletitled, 1476-P: Genetic Relationships between Puberty Onset and Type 2 Diabetes
Meeting Abstracts

141-OR: Associations between Type 2 Diabetes Partitioned/Process-Specific Polygenic Scores and Metabolic Traits

LAUREN E. WEDEKIND, WEN-CHI HSUEH, SAYUKO KOBES, LESLIE BAIER, CLIFTON BOGARDUS, III, WILLIAM C. KNOWLER, ANUBHA MAHAJAN, MARK MCCARTHY, ROBERT L. HANSON
Journal: Diabetes
Diabetes 2022;71(Supplement_1):141-OR
https://doi.org/10.2337/db22-141-OR
Published: 01 June 2022
View articletitled, 141-OR: Associations between Type 2 Diabetes Partitioned/Process-Specific Polygenic Scores and Metabolic Traits
Meeting Abstracts

1184-P: Adolescent Growth Spurt and Type 2 Diabetes Risk in an American Indian Population

MARIA J. RAMIREZ-LUZURIAGA, SAYUKO KOBES, MADHUMITA SINHA, WILLIAM C. KNOWLER, ROBERT L. HANSON
Journal: Diabetes
Diabetes 2022;71(Supplement_1):1184-P
https://doi.org/10.2337/db22-1184-P
Published: 01 June 2022
View articletitled, 1184-P: Adolescent Growth Spurt and Type 2 Diabetes Risk in an American Indian Population
Meeting Abstracts

160-OR: Increased Adiposity and Low Height-for-Age in Early Childhood Is Associated with Later Metabolic Risk in American Indian Children and Adolescents

MARIA J. RAMIREZ-LUZURIAGA, SAYUKO KOBES, MADHUMITA SINHA, WILLIAM C. KNOWLER, ROBERT L. HANSON
Journal: Diabetes
Diabetes 2021;70(Supplement_1):160-OR
https://doi.org/10.2337/db21-160-OR
Published: 01 June 2021
View articletitled, 160-OR: Increased Adiposity and Low Height-for-Age in Early Childhood Is Associated with Later Metabolic Risk in American Indian Children and Adolescents
Meeting Abstracts

1132-P: Genetic Relationships between Birth Weight and Type 2 Diabetes

LAUREN E. WEDEKIND, WEN-CHI HSUEH, MUIDEEN OLAIYA, SAYUKO KOBES, LESLIE BAIER, WILLIAM C. KNOWLER, ANUBHA MAHAJAN, MARK MCCARTHY, ROBERT L. HANSON
Journal: Diabetes
Diabetes 2021;70(Supplement_1):1132-P
https://doi.org/10.2337/db21-1132-P
Published: 01 June 2021
View articletitled, 1132-P: Genetic Relationships between Birth Weight and Type 2 Diabetes
Meeting Abstracts

1977-P: Whole-Exome Sequencing Followed by Functional Analysis to Identify Variants That May Influence Body Mass Index (BMI) via a Role in Adipogenesis

YUNHUA L. MULLER, SAMANTHA E. DAY, CIGDEM KOROGLU, SAYUKO KOBES, ROBERT L. HANSON, WILLIAM C. KNOWLER, HYE IN KIM, CRISTOPHER VAN HOUT, NEHAL GOSALIA, ALAN R. SHULDINER, CLIFTON BOGARDUS, III, LESLIE BAIER
Journal: Diabetes
Diabetes 2020;69(Supplement_1):1977-P
https://doi.org/10.2337/db20-1977-P
Published: 01 June 2020
View articletitled, 1977-P: Whole-Exome Sequencing Followed by Functional Analysis to Identify Variants That May Influence Body Mass Index (BMI) via a Role in Adipogenesis
Meeting Abstracts

2018-P: Whole-Genome Sequence Identifies Potentially Functional Variants in Cytochrome B5 Type A (CYB5A) that Associate with Obesity in Southwest American Indians

SAMANTHA E. DAY, MICHAEL TRAURIG, PAOLO PIAGGI, PANKAJ KUMAR, SAYUKO KOBES, ROBERT L. HANSON, CLIFTON BOGARDUS, III, LESLIE BAIER
Journal: Diabetes
Diabetes 2020;69(Supplement_1):2018-P
https://doi.org/10.2337/db20-2018-P
Published: 01 June 2020
View articletitled, 2018-P: Whole-Genome Sequence Identifies Potentially Functional Variants in Cytochrome B5 Type A (CYB5A) that Associate with Obesity in Southwest American Indians
Meeting Abstracts

1642-P: Colocalization Analyses of Genetic Associations of Type 2 Diabetes with DNA Methylation on Chromosome 11p in American Indians

ROBERT L. HANSON, SAYUKO KOBES, WEN-CHI HSUEH, YUNHUA L. MULLER, WILLIAM C. KNOWLER, LESLIE BAIER
Journal: Diabetes
Diabetes 2020;69(Supplement_1):1642-P
https://doi.org/10.2337/db20-1642-P
Published: 01 June 2020
View articletitled, 1642-P: Colocalization Analyses of Genetic Associations of Type 2 Diabetes with DNA Methylation on Chromosome 11p in American Indians
Meeting Abstracts

1460-P: Type 2 Diabetes Polygenic Score in Addition to Clinical Factors for Prediction of Diabetes Incidence in an Indigenous American Population

LAUREN E. WEDEKIND, SAYUKO KOBES, WEN-CHI HSUEH, LESLIE BAIER, WILLIAM C. KNOWLER, ANUBHA MAHAJAN, MARK I. MCCARTHY, ROBERT L. HANSON
Journal: Diabetes
Diabetes 2020;69(Supplement_1):1460-P
https://doi.org/10.2337/db20-1460-P
Published: 01 June 2020
View articletitled, 1460-P: Type 2 Diabetes Polygenic Score in Addition to Clinical Factors for Prediction of Diabetes Incidence in an Indigenous American Population
Meeting Abstracts

271-OR: Whole-Exome Sequence Identifies Potentially Functional Rare Variants in Bardet-Biedl Syndrome (BBS) Genes that Associate with Obesity in American Indians

SAMANTHA E. DAY, YUNHUA L. MULLER, SAYUKO KOBES, HYE IN KIM, CRISTOPHER V. VAN HOUT, NEHAL GOSALIA, BIN YE, ALAN R. SHULDINER, ROBERT L. HANSON, CIGDEM KOROGLU ALTOK, CLIFTON BOGARDUS, III, LESLIE J. BAIER
Journal: Diabetes
Diabetes 2019;68(Supplement_1):271-OR
https://doi.org/10.2337/db19-271-OR
Published: 01 June 2019
View articletitled, 271-OR: Whole-Exome Sequence Identifies Potentially Functional Rare Variants in Bardet-Biedl Syndrome (BBS) Genes that Associate with Obesity in American Indians
Meeting Abstracts

1715-P: Identifying Potentially Functional Variants in Regulatory Regions in KCNQ1 that Associate with Type 2 Diabetes in American Indians

YUNHUA L. MULLER, SAMANTHA E. DAY, SAYUKO KOBES, WILLIAM C. KNOWLER, ROBERT L. HANSON, CLIFTON BOGARDUS, III, LESLIE J. BAIER
Journal: Diabetes
Diabetes 2019;68(Supplement_1):1715-P
https://doi.org/10.2337/db19-1715-P
Published: 01 June 2019
View articletitled, 1715-P: Identifying Potentially Functional Variants in Regulatory Regions in KCNQ1 that Associate with Type 2 Diabetes in American Indians
Meeting Abstracts

1701-P: Genome-Wide Association Study Identifies Novel Potential Associations with Birth Weight in a Southwestern American Indian Population

LAUREN E. WEDEKIND, WEN-CHI HSUEH, SAYUKO KOBES, MUIDEEN T. OLAIYA, WILLIAM C. KNOWLER, LESLIE J. BAIER, ROBERT L. HANSON
Journal: Diabetes
Diabetes 2019;68(Supplement_1):1701-P
https://doi.org/10.2337/db19-1701-P
Published: 01 June 2019
View articletitled, 1701-P: Genome-Wide Association Study Identifies Novel Potential Associations with Birth Weight in a Southwestern American Indian Population
Meeting Abstracts

1709-P: Assessing the Role of 211 “Established” Type 2 Diabetes Variants in American Indians

ROBERT L. HANSON, LAUREN E. WEDEKIND, WEN-CHI HSUEH, SAYUKO KOBES, LESLIE J. BAIER, CLIFTON BOGARDUS, III, WILLIAM C. KNOWLER
Journal: Diabetes
Diabetes 2019;68(Supplement_1):1709-P
https://doi.org/10.2337/db19-1709-P
Published: 01 June 2019
View articletitled, 1709-P: Assessing the Role of 211 “Established” Type 2 Diabetes Variants in American Indians
Meeting Abstracts

1597-P: Incidence of Diabetes in Young Adult South Asians Compared with Pima Indians

K.M. VENKAT NARAYAN, DIMPLE KONDAL, SAYUKO KOBES, MOHAN DEEPA, NATALIE R. DAYA, SHIVANI A. PATEL, RANJIT MOHAN ANJANA, LISA R. STAIMEZ, MOHAMMED K. ALI, UNJALI GUJRAL, DORAIRAJ PRABHAKARAN, ROOPA SHIVASHANKAR, MASOOD KADIR, ELIZABETH SELVIN, VISWANATHAN MOHAN, ROBERT L. HANSON, NIKHIL TANDON
Journal: Diabetes
Diabetes 2019;68(Supplement_1):1597-P
https://doi.org/10.2337/db19-1597-P
Published: 01 June 2019
View articletitled, 1597-P: Incidence of Diabetes in Young Adult South Asians Compared with Pima Indians
Meeting Abstracts

1598-P: Incidence of Diabetes in South Asian Adults in Urban India/Pakistan Compared with Blacks and Whites in U.S.

K.M. VENKAT NARAYAN, DIMPLE KONDAL, NATALIE R. DAYA, SHIVANI A. PATEL, MOHAN DEEPA, RANJIT MOHAN ANJANA, LISA R. STAIMEZ, UNJALI GUJRAL, SAYUKO KOBES, ROOPA SHIVASHANKAR, MOHAMMED K. ALI, MASOOD KADIR, DORAIRAJ PRABHAKARAN, ROBERT L. HANSON, VISWANATHAN MOHAN, ELIZABETH SELVIN, NIKHIL TANDON
Journal: Diabetes
Diabetes 2019;68(Supplement_1):1598-P
https://doi.org/10.2337/db19-1598-P
Published: 01 June 2019
View articletitled, 1598-P: Incidence of Diabetes in South Asian Adults in Urban India/Pakistan Compared with Blacks and Whites in U.S.
Meeting Abstracts

125-OR: Child Growth Tracking and Type 2 Diabetes Risk: A Life Course Analysis

MUIDEEN T. OLAIYA, WILLIAM C. KNOWLER, ROBERT L. HANSON, SAYUKO KOBES, ROBERT NELSON, MADHUMITA SINHA
Journal: Diabetes
Diabetes 2019;68(Supplement_1):125-OR
https://doi.org/10.2337/db19-125-OR
Published: 01 June 2019
View articletitled, 125-OR: Child Growth Tracking and Type 2 Diabetes Risk: A Life Course Analysis
Meeting Abstracts

Differential Effects of Birth Weight on Early-Onset Type 2 Diabetes in Adolescents and Young Adults

MUIDEEN T. OLAIYA, MADHUMITA SINHA, ROBERT L. HANSON, SAYUKO KOBES, ROBERT NELSON, WILLIAM C. KNOWLER
Journal: Diabetes
Diabetes 2018;67(Supplement_1):153-LB
https://doi.org/10.2337/db18-153-LB
Published: 01 July 2018
View articletitled, Differential Effects of Birth Weight on Early-Onset Type 2 Diabetes in Adolescents and Young Adults
Meeting Abstracts

A Low-Frequency Amerindian Specific Variant in PALD1, a Negative Regulator of Insulin Signaling, Associates with Type 2 Diabetes

ANUP K. NAIR, JEFF R. SUTHERLAND, GREGORY R. ELSON, PAOLO PIAGGI, SAYUKO KOBES, ROBERT L. HANSON, CLIFTON BOGARDUS, III, LESLIE BAIER
Journal: Diabetes
Diabetes 2018;67(Supplement_1):213-LB
https://doi.org/10.2337/db18-213-LB
Published: 01 July 2018
View articletitled, A Low-Frequency Amerindian Specific Variant in PALD1, a Negative Regulator of Insulin Signaling, Associates with Type 2 Diabetes
Meeting Abstracts

Genome-Wide Association Study of Inflammatory Cytokines in Southwestern Native Americans Identifies Novel Association between WWOX and Serum TNF-? Levels

LAUREN E. WEDEKIND, MARY WALTER, SAYUKO KOBES, PENG CHEN, WEN-CHI HSUEH, ROBERT NELSON, LESLIE BAIER, WILLIAM C. KNOWLER, ROBERT L. HANSON
Journal: Diabetes
Diabetes 2018;67(Supplement_1):1713-P
https://doi.org/10.2337/db18-1713-P
Published: 01 July 2018
View articletitled, Genome-Wide Association Study of Inflammatory Cytokines in Southwestern Native Americans Identifies Novel Association between WWOX and Serum TNF-? Levels