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Meeting Abstracts

1693-P: Irisin Levels, Glycometabolic Characteristics, and Muscle Performance in Type 2 Diabetes Patients with Sarcopenic or Nonsarcopenic Obesity

ERICA ROSSI, LUDOVICO DI GIOIA, NICOLA MARRANO, SEBASTIO PERRINI, LUIGI LAVIOLA, ANNALISA NATALICCHIO, FRANCESCO GIORGINO
Journal: Diabetes
Diabetes 2024;73(Supplement_1):1693-P
https://doi.org/10.2337/db24-1693-P
Published: 14 June 2024
View article titled, 1693-P: Irisin Levels, Glycometabolic Characteristics, and Muscle Performance in Type 2 Diabetes Patients with Sarcopenic or Nonsarcopenic Obesity
Meeting Abstracts

783-P: Efficacy of GLP-1RA according to Type 2 Diabetes Phenotypes—A Monocentric Retrospective Study

IRENE CARUSO, FIORELLA GIORDANO, LUDOVICO DI GIOIA, IMMACOLATA I. MATICHECCHIA, ANGELO CIGNARELLI, GIAN PIO SORICE, SEBASTIO PERRINI, ANNALISA NATALICCHIO, LUIGI LAVIOLA, FRANCESCO GIORGINO
Journal: Diabetes
Diabetes 2024;73(Supplement_1):783-P
https://doi.org/10.2337/db24-783-P
Published: 14 June 2024
View article titled, 783-P: Efficacy of GLP-1RA according to Type 2 Diabetes Phenotypes—A Monocentric Retrospective Study
Meeting Abstracts

438-P: Glucose-Dependent Insulinotropic Polypeptide Prevents Palmitate-Induced Apoptosis, but Not Autophagy and Stress Kinase Activation in Human Cardiac Progenitor Cells

ISABELLA CALDERONI, ROSSELLA DORIA, CRISTINA CACCIOPPOLI, CARMELA COLABUFO, VALENTINA ANNAMARIA GENCHI, GIUSEPPE PALMA, GIUSEPPE SANTARPINO, ALDO D. MILANO, TOMASO BOTTIO, ANNA LEONARDINI, ANNALISA NATALICCHIO, SEBASTIO PERRINI, ANGELO CIGNARELLI, FRANCESCO GIORGINO, LUIGI LAVIOLA
Journal: Diabetes
Diabetes 2024;73(Supplement_1):438-P
https://doi.org/10.2337/db24-438-P
Published: 14 June 2024
View article titled, 438-P: Glucose-Dependent Insulinotropic Polypeptide Prevents Palmitate-Induced Apoptosis, but Not Autophagy and Stress Kinase Activation in Human Cardiac Progenitor Cells
Meeting Abstracts

307-OR: Defective G-CSF in the Secretome of Epicardial Adipose Cells Favors Apoptosis and Cellular Stress of Cardiac Progenitor Cells in Human Obesity

GIUSEPPE PALMA, CRISTINA CACCIOPPOLI, ROSSELLA DORIA, VALENTINA ANNAMARIA GENCHI, ISABELLA CALDERONI, TOMASO BOTTIO, GIUSEPPE SANTARPINO, ANGELO CIGNARELLI, ANNALISA NATALICCHIO, LUIGI LAVIOLA, ANGELA PEZZOLLA, ANGELA M. VALVERDE, ALDO D. MILANO, FRANCESCO GIORGINO, SEBASTIO PERRINI
Journal: Diabetes
Diabetes 2024;73(Supplement_1):307-OR
https://doi.org/10.2337/db24-307-OR
Published: 14 June 2024
View article titled, 307-OR: Defective G-CSF in the Secretome of Epicardial Adipose Cells Favors Apoptosis and Cellular Stress of Cardiac Progenitor Cells in Human Obesity
Meeting Abstracts

38-OR: Insulin Prevents Palmitate-Induced Stress Kinase Activation, Autophagy, and Apoptosis in Human Cardiac Progenitor Cells

ISABELLA CALDERONI, ROSSELLA DORIA, CRISTINA CACCIOPPOLI, VALENTINA ANNAMARIA GENCHI, GIUSEPPE PALMA, GIUSEPPE SANTARPINO, ALDO D. MILANO, ANNA LEONARDINI, ANNALISA NATALICCHIO, SEBASTIO PERRINI, ANGELO CIGNARELLI, FRANCESCO GIORGINO, LUIGI LAVIOLA
Journal: Diabetes
Diabetes 2023;72(Supplement_1):38-OR
https://doi.org/10.2337/db23-38-OR
Published: 20 June 2023
View article titled, 38-OR: Insulin Prevents Palmitate-Induced Stress Kinase Activation, Autophagy, and Apoptosis in Human Cardiac Progenitor Cells
Meeting Abstracts

246-OR: Dapagliflozin Counteracts the Proapoptotic Effects of the Secretome of Visceral Adipose Cells from Obese Subjects in Human Cardiac Progenitor Cells via the SGLT2 Cotransporter

GIUSEPPE PALMA, CRISTINA CACCIOPPOLI, ROSSELLA DORIA, VALENTINA ANNAMARIA GENCHI, ISABELLA CALDERONI, ANTONIO BRAUN, GIUSEPPE SANTARPINO, ALDO D. MILANO, ANGELO CIGNARELLI, ANNALISA NATALICCHIO, LUIGI LAVIOLA, ANGELA PEZZOLLA, FRANCESCO GIORGINO, SEBASTIO PERRINI
Journal: Diabetes
Diabetes 2023;72(Supplement_1):246-OR
https://doi.org/10.2337/db23-246-OR
Published: 20 June 2023
View article titled, 246-OR: Dapagliflozin Counteracts the Proapoptotic Effects of the Secretome of Visceral Adipose Cells from Obese Subjects in Human Cardiac Progenitor Cells via the SGLT2 Cotransporter
Meeting Abstracts

1661-P: The Myokine Irisin Is Endocytosed and Signals through an αV Integrin-Independent Mechanism in Pancreatic ß-Cells

NICOLA MARRANO, ANNA BORRELLI, GIUSEPPINA BIONDI, MARTINA RELLA, ANGELO CIGNARELLI, SEBASTIO PERRINI, LUIGI LAVIOLA, FRANCESCO GIORGINO, ANNALISA NATALICCHIO
Journal: Diabetes
Diabetes 2023;72(Supplement_1):1661-P
https://doi.org/10.2337/db23-1661-P
Published: 20 June 2023
View article titled, 1661-P: The Myokine Irisin Is Endocytosed and Signals through an αV Integrin-Independent Mechanism in Pancreatic ß-Cells
Journal Articles

The p66Shc Protein Mediates Insulin Resistance and Secretory Dysfunction in Pancreatic β-Cells Under Lipotoxic Conditions

Giuseppina Biondi, Nicola Marrano, Lucia Dipaola, Anna Borrelli, Martina Rella, Rossella D’Oria, Valentina A. Genchi, Cristina Caccioppoli, Immacolata Porreca, Angelo Cignarelli, Sebastio Perrini, Piero Marchetti, Leonardo Vincenti, Luigi Laviola, Francesco Giorgino, Annalisa Natalicchio
Journal: Diabetes
Diabetes 2022;71(8):1763–1771
https://doi.org/10.2337/db21-1066
Published: 21 August 2022
View article titled, The p66<sup>Shc</sup> Protein Mediates Insulin Resistance and Secretory Dysfunction in Pancreatic β-Cells Under Lipotoxic Conditions
Open the PDF for The p66<sup>Shc</sup> Protein Mediates Insulin Resistance and Secretory Dysfunction in Pancreatic β-Cells Under Lipotoxic Conditions in another window
Meeting Abstracts

441-P: Oleate Prevents Palmitate-Induced Abnormalities in Insulin Signaling in Human Cardiac Progenitor Cells by Inhibiting p38 MAPK and c-Jun Phosphorylation

ROSSELLA DORIA, ISABELLA CALDERONI, CRISTINA CACCIOPPOLI, VALENTINA ANNAMARIA GENCHI, GIUSEPPE SANTARPINO, ANNA LEONARDINI, ANNALISA NATALICCHIO, SEBASTIO PERRINI, ANGELO CIGNARELLI, FRANCESCO GIORGINO, LUIGI LAVIOLA
Journal: Diabetes
Diabetes 2022;71(Supplement_1):441-P
https://doi.org/10.2337/db22-441-P
Published: 01 June 2022
View article titled, 441-P: Oleate Prevents Palmitate-Induced Abnormalities in Insulin Signaling in Human Cardiac Progenitor Cells by Inhibiting p38 MAPK and c-Jun Phosphorylation
Meeting Abstracts

1375-P: Effects of Irisin Administration on Pancreatic Islets of Diabetic Mice

NICOLA MARRANO, GIUSEPPINA BIONDI, ANNA BORRELLI, LUCA ROBERTO, ANGELO CIGNARELLI, SEBASTIO PERRINI, LUIGI LAVIOLA, FRANCESCO GIORGINO, ANNALISA NATALICCHIO
Journal: Diabetes
Diabetes 2022;71(Supplement_1):1375-P
https://doi.org/10.2337/db22-1375-P
Published: 01 June 2022
View article titled, 1375-P: Effects of Irisin Administration on Pancreatic Islets of Diabetic Mice
Meeting Abstracts

1414-P: Dapagliflozin Protects Human Cardiac Progenitor Cells from Deleterious Effects of the Secretome from Visceral Adipose Cells of Obese Subjects

GIUSEPPE PALMA, CRISTINA CACCIOPPOLI, ROSSELLA DORIA, VALENTINA ANNAMARIA GENCHI, GIUSEPPE SANTARPINO, ANGELO CIGNARELLI, ANNALISA NATALICCHIO, LUIGI LAVIOLA, ANGELA PEZZOLLA, FRANCESCO GIORGINO, SEBASTIO PERRINI
Journal: Diabetes
Diabetes 2022;71(Supplement_1):1414-P
https://doi.org/10.2337/db22-1414-P
Published: 01 June 2022
View article titled, 1414-P: Dapagliflozin Protects Human Cardiac Progenitor Cells from Deleterious Effects of the Secretome from Visceral Adipose Cells of Obese Subjects
Meeting Abstracts

241-OR: Effects of Antidiabetes Therapies on Irisin Levels in Type 2 Diabetes Patients

ANNALISA NATALICCHIO, NICOLA MARRANO, GIUSEPPINA BIONDI, ANNA MONTEDORO, GIULIA LE GRAZIE, LUDOVICO DI GIOIA, FRANCESCA GUARINI, ANNA BORRELLI, ANGELO CIGNARELLI, SEBASTIO PERRINI, LUIGI LAVIOLA, FRANCESCO GIORGINO
Journal: Diabetes
Diabetes 2021;70(Supplement_1):241-OR
https://doi.org/10.2337/db21-241-OR
Published: 01 June 2021
View article titled, 241-OR: Effects of Antidiabetes Therapies on Irisin Levels in Type 2 Diabetes Patients
Meeting Abstracts

1223-P: Effects of Bariatric Surgery on Quality of Life, Body Image, and Sex Life in Obese Women

LUDOVICO DI GIOIA, SEBASTIO PERRINI, ANTONIO BRAUN, ERICA ROSSI, FIORELLA GIORDANO, FRANCESCA GUARINI, EDOARDO SICILIANO, ANGELO CIGNARELLI, ANNA LEONARDINI, ANNALISA NATALICCHIO, LUIGI LAVIOLA, ALESSANDRO BERTOLINO, FRANCESCO GIORGINO
Journal: Diabetes
Diabetes 2021;70(Supplement_1):1223-P
https://doi.org/10.2337/db21-1223-P
Published: 01 June 2021
View article titled, 1223-P: Effects of Bariatric Surgery on Quality of Life, Body Image, and Sex Life in Obese Women
Meeting Abstracts

1230-P: Isolation of Functional Endothelial Progenitor Cells from Human Adipose Tissue

CRISTINA CACCIOPPOLI, SEBASTIO PERRINI, VALENTINA ANNAMARIA GENCHI, ROSSELLA DORIA, GIUSEPPE PALMA, ANGELO CIGNARELLI, ANNALISA NATALICCHIO, LUIGI LAVIOLA, FRANCESCO GIORGINO
Journal: Diabetes
Diabetes 2021;70(Supplement_1):1230-P
https://doi.org/10.2337/db21-1230-P
Published: 01 June 2021
View article titled, 1230-P: Isolation of Functional Endothelial Progenitor Cells from Human Adipose Tissue
Meeting Abstracts

374-P: Oleate Prevents Palmitate-Induced Abnormalities in Insulin Signaling in Human Cardiac Progenitor Cells

ROSSELLA DORIA, CRISTINA CACCIOPPOLI, ROSSELLA SCHIPANI, VALENTINA ANNAMARIA GENCHI, ANNA LEONARDINI, ANNALISA NATALICCHIO, SEBASTIO PERRINI, ANGELO CIGNARELLI, LUIGI LAVIOLA, FRANCESCO GIORGINO
Journal: Diabetes
Diabetes 2021;70(Supplement_1):374-P
https://doi.org/10.2337/db21-374-P
Published: 01 June 2021
View article titled, 374-P: Oleate Prevents Palmitate-Induced Abnormalities in Insulin Signaling in Human Cardiac Progenitor Cells
Meeting Abstracts

2094-P: Effects of Irisin on Human Pancreatic Islets from Type 2 Diabetic Subjects

NICOLA MARRANO, ANNALISA NATALICCHIO, GIUSEPPINA BIONDI, ANGELO CIGNARELLI, LEONARDO VINCENTI, LUIGI G. LUPO, SEBASTIO PERRINI, LUIGI LAVIOLA, FRANCESCO GIORGINO
Journal: Diabetes
Diabetes 2020;69(Supplement_1):2094-P
https://doi.org/10.2337/db20-2094-P
Published: 01 June 2020
View article titled, 2094-P: Effects of Irisin on Human Pancreatic Islets from Type 2 Diabetic Subjects
Meeting Abstracts

2038-P: The Somatostatin Analog Pasireotide Reduces Pancreatic ß-Cell Function and Survival, and Both Incretin-Based Drugs and Irisin Revert These Effects

ANNALISA NATALICCHIO, GIUSEPPINA BIONDI, NICOLA MARRANO, LEONARDO VINCENTI, ANGELO CIGNARELLI, SEBASTIO PERRINI, LUIGI LAVIOLA, FRANCESCO GIORGINO
Journal: Diabetes
Diabetes 2020;69(Supplement_1):2038-P
https://doi.org/10.2337/db20-2038-P
Published: 01 June 2020
View article titled, 2038-P: The Somatostatin Analog Pasireotide Reduces Pancreatic ß-Cell Function and Survival, and Both Incretin-Based Drugs and Irisin Revert These Effects
Meeting Abstracts

410-P: Effects of Palmitate and Oleate on Apoptosis, Autophagy, Stress, Kinase Phosphorylation, and Enzymes of Fatty Acid Oxidation in Human Cardiac Progenitor Cells from Control and Diabetic Subjects

LUIGI LAVIOLA, ROSSELLA SCHIPANI, ROSSELLA DORIA, CRISTINA CACCIOPPOLI, ANNA LEONARDINI, ANNALISA NATALICCHIO, SEBASTIO PERRINI, ANGELO CIGNARELLI, FRANCESCO GIORGINO
Journal: Diabetes
Diabetes 2020;69(Supplement_1):410-P
https://doi.org/10.2337/db20-410-P
Published: 01 June 2020
View article titled, 410-P: Effects of Palmitate and Oleate on Apoptosis, Autophagy, Stress, Kinase Phosphorylation, and Enzymes of Fatty Acid Oxidation in Human Cardiac Progenitor Cells from Control and Diabetic Subjects
Meeting Abstracts

1134-P: The Secretome of Visceral Adipose Cells Induces Apoptosis of Cardiac Progenitor Cells in Human Obesity: Protective Effects of the SGLT2 Inhibitor Dapagliflozin

STEFANIA PORRO, SEBASTIO PERRINI, CRISTINA CACCIOPPOLI, ROSSELLA DORIA, VALENTINA ANNAMARIA GENCHI, ROSSELLA SCHIPANI, ANGELO CIGNARELLI, ANNALISA NATALICCHIO, LUIGI LAVIOLA, FRANCESCO GIORGINO
Journal: Diabetes
Diabetes 2020;69(Supplement_1):1134-P
https://doi.org/10.2337/db20-1134-P
Published: 01 June 2020
View article titled, 1134-P: The Secretome of Visceral Adipose Cells Induces Apoptosis of Cardiac Progenitor Cells in Human Obesity: Protective Effects of the SGLT2 Inhibitor Dapagliflozin
Meeting Abstracts

2266-PUB: Effects of Combined Exercise Protocols on Glucose Variability in Patients with Autoimmune Diabetes on CSII Therapy

ANGELO CIGNARELLI, GIUSEPPE LISCO, LUDOVICO DI GIOIA, ANNALISA NATALICCHIO, SEBASTIO PERRINI, LUIGI LAVIOLA, FRANCESCO GIORGINO
Journal: Diabetes
Diabetes 2019;68(Supplement_1):2266-PUB
https://doi.org/10.2337/db19-2266-PUB
Published: 01 June 2019
View article titled, 2266-PUB: Effects of Combined Exercise Protocols on Glucose Variability in Patients with Autoimmune Diabetes on CSII Therapy