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Sefina Arif
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Journal Articles

Immune and Metabolic Effects of Antigen-Specific Immunotherapy Using Multiple β-Cell Peptides in Type 1 Diabetes

Yuk-Fun Liu, Jake Powrie, Sefina Arif, Jennie H.M. Yang, Evangelia Williams, Leena Khatri, Mamta Joshi, Loic Lhuillier, Nikolaos Fountoulakis, Emma Smith, Craig Beam, Anna Lorenc, Mark Peakman, Timothy Tree
Journal: Diabetes
Diabetes 2022;71(4):722–732
https://doi.org/10.2337/db21-0728
Published: 24 January 2022
View article titled, Immune and Metabolic Effects of Antigen-Specific Immunotherapy Using Multiple β-Cell Peptides in Type 1 Diabetes
Open the PDF for Immune and Metabolic Effects of Antigen-Specific Immunotherapy Using Multiple β-Cell Peptides in Type 1 Diabetes in another window
Meeting Abstracts

The MultiPepT1De Study—Examining the Safety of Peptide Immunotherapy Using Multiple Islet Antigens in Recent-Onset Type 1 Diabetes

YUK-FUN LIU, JAKE K. POWRIE, SEFINA ARIF, NIKOLAOS FOUNTOULAKIS, MAMTA JOSHI, EMMA L. SMITH, FOTEINI STRIMENOPOULOU, MOIRA THOMSON, MARK PEAKMAN
Journal: Diabetes
Diabetes 2018;67(Supplement_1):1733-P
https://doi.org/10.2337/db18-1733-P
Published: 01 July 2018
View article titled, The MultiPepT1De Study—Examining the Safety of Peptide Immunotherapy Using Multiple Islet Antigens in Recent-Onset Type 1 Diabetes
Journal Articles

Discovery of a Selective Islet Peptidome Presented by the Highest-Risk HLA-DQ8trans Molecule

Menno van Lummel, Peter A. van Veelen, Arnoud H. de Ru, Jos Pool, Tatjana Nikolic, Sandra Laban, Antoinette Joosten, Jan W. Drijfhout, Iria Gómez-Touriño, Sefina Arif, Henk J. Aanstoot, Mark Peakman, Bart O. Roep
Journal: Diabetes
Diabetes 2016;65(3):732–741
https://doi.org/10.2337/db15-1031
Published: 30 December 2015
View article titled, Discovery of a Selective Islet Peptidome Presented by the Highest-Risk HLA-DQ8<em>trans</em> Molecule
Open the PDF for Discovery of a Selective Islet Peptidome Presented by the Highest-Risk HLA-DQ8<em>trans</em> Molecule in another window
Includes: Supplementary data
Journal Articles

Erratum. Blood and Islet Phenotypes Indicate Immunological Heterogeneity in Type 1 Diabetes. Diabetes 2014;63: 3835–3845

Sefina Arif, Pia Leete, Vy Nguyen, Katherine Marks, Nurhanani Mohamed Nor, Megan Estorninho, Deborah Kronenberg-Versteeg, Polly J. Bingley, John A. Todd, Catherine Guy, David B. Dunger, Jake Powrie, Abby Willcox, Alan K. Foulis, Sarah J. Richardson, Emanuele de Rinaldis, Noel G. Morgan, Anna Lorenc, Mark Peakman
Journal: Diabetes
Diabetes 2015;64(9):3334
https://doi.org/10.2337/db15-er09a
Published: 13 August 2015
View article titled, Erratum. Blood and Islet Phenotypes Indicate Immunological Heterogeneity in Type 1 Diabetes. Diabetes 2014;63: 3835–3845
Open the PDF for Erratum. Blood and Islet Phenotypes Indicate Immunological Heterogeneity in Type 1 Diabetes. Diabetes 2014;63: 3835–3845 in another window
Journal Articles

Blood and Islet Phenotypes Indicate Immunological Heterogeneity in Type 1 Diabetes

Sefina Arif, Pia Leete, Vy Nguyen, Katherine Marks, Nurhanani Mohamed Nor, Megan Estorninho, Deborah Kronenberg-Versteeg, Polly J. Bingley, John A. Todd, Catherine Guy, David B. Dunger, Jake Powrie, Abby Willcox, Alan K. Foulis, Sarah J. Richardson, Emanuele de Rinaldis, Noel G. Morgan, Anna Lorenc, Mark Peakman
Journal: Diabetes
Diabetes 2014;63(11):3835–3845
https://doi.org/10.2337/db14-0365
Published: 13 October 2014
View article titled, Blood and Islet Phenotypes Indicate Immunological Heterogeneity in Type 1 Diabetes
Open the PDF for Blood and Islet Phenotypes Indicate Immunological Heterogeneity in Type 1 Diabetes in another window
Includes: Supplementary data
Journal Articles

Posttranslational Modification of HLA-DQ Binding Islet Autoantigens in Type 1 Diabetes

Menno van Lummel, Gaby Duinkerken, Peter A. van Veelen, Arnoud de Ru, Robert Cordfunke, Arnaud Zaldumbide, Iria Gomez-Touriño, Sefina Arif, Mark Peakman, Jan W. Drijfhout, Bart O. Roep
Journal: Diabetes
Diabetes 2014;63(1):237–247
https://doi.org/10.2337/db12-1214
Published: 13 December 2013
View article titled, Posttranslational Modification of HLA-DQ Binding Islet Autoantigens in Type 1 Diabetes
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Includes: Supplementary data
Journal Articles

Peripheral and Islet Interleukin-17 Pathway Activation Characterizes Human Autoimmune Diabetes and Promotes Cytokine-Mediated β-Cell Death

Sefina Arif, Fabrice Moore, Katherine Marks, Thomas Bouckenooghe, Colin M. Dayan, Raquel Planas, Marta Vives-Pi, Jake Powrie, Timothy Tree, Piero Marchetti, Guo Cai Huang, Esteban N. Gurzov, Ricardo Pujol-Borrell, Decio L. Eizirik, Mark Peakman
Journal: Diabetes
Diabetes 2011;60(8):2112–2119
https://doi.org/10.2337/db10-1643
Published: 18 July 2011
View article titled, Peripheral and Islet Interleukin-17 Pathway Activation Characterizes Human Autoimmune Diabetes and Promotes Cytokine-Mediated β-Cell Death
Open the PDF for Peripheral and Islet Interleukin-17 Pathway Activation Characterizes Human Autoimmune Diabetes and Promotes Cytokine-Mediated β-Cell Death in another window
Includes: Supplementary data
Journal Articles

Naturally Arising Human CD4 T-Cells That Recognize Islet Autoantigens and Secrete Interleukin-10 Regulate Proinflammatory T-Cell Responses via Linked Suppression

Timothy I.M. Tree, Jennifer Lawson, Hannah Edwards, Ania Skowera, Sefina Arif, Bart O. Roep, Mark Peakman
Journal: Diabetes
Diabetes 2010;59(6):1451–1460
https://doi.org/10.2337/db09-0503
Published: 18 March 2010
View article titled, Naturally Arising Human CD4 T-Cells That Recognize Islet Autoantigens and Secrete Interleukin-10 Regulate Proinflammatory T-Cell Responses via Linked Suppression
Open the PDF for Naturally Arising Human CD4 T-Cells That Recognize Islet Autoantigens and Secrete Interleukin-10 Regulate Proinflammatory T-Cell Responses via Linked Suppression in another window
Includes: Supplementary data
Journal Articles

Validity and Reproducibility of Measurement of Islet Autoreactivity by T-Cell Assays in Subjects With Early Type 1 Diabetes

Kevan C. Herold, Barbara Brooks-Worrell, Jerry Palmer, H. Michael Dosch, Mark Peakman, Peter Gottlieb, Helena Reijonen, Sefina Arif, Lisa M. Spain, Clinton Thompson, John M. Lachin, the Type 1 Diabetes TrialNet Research Group
Journal: Diabetes
Diabetes 2009;58(11):2588–2595
https://doi.org/10.2337/db09-0249
Published: 12 August 2009
View article titled, Validity and Reproducibility of Measurement of Islet Autoreactivity by T-Cell Assays in Subjects With Early Type 1 Diabetes
Open the PDF for Validity and Reproducibility of Measurement of Islet Autoreactivity by T-Cell Assays in Subjects With Early Type 1 Diabetes in another window
Includes: Supplementary data