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Journal Articles

PNLIPRP1 hypermethylation in exocrine pancreas links type 2 diabetes and cholesterol metabolism

Diabetes db240215

Published: 13 August 2024

View article titled, PNLIPRP1 hypermethylation in exocrine pancreas links type 2 diabetes and cholesterol metabolism

Journal Articles

Pancreas Pathology of Latent Autoimmune Diabetes in Adults (LADA) in Patients and in a LADA Rat Model Compared With Type 1 Diabetes

Anne Jörns, Dirk Wedekind, Joachim Jähne, Sigurd Lenzen

Diabetes 2020;69(4):624–633

https://doi.org/10.2337/db19-0865

Published: 23 January 2020

View article titled, Pancreas Pathology of Latent Autoimmune Diabetes in Adults (LADA) in Patients and in a LADA Rat Model Compared With Type 1 Diabetes

Includes: Supplementary data

Journal Articles

β-Cell DNA Damage Response Promotes Islet Inflammation in Type 1 Diabetes

Elad Horwitz, Lars Krogvold, Sophia Zhitomirsky, Avital Swisa, Maya Fischman, Tsuria Lax, Tehila Dahan, Noa Hurvitz, Noa Weinberg-Corem, Agnes Klochendler, Alvin C. Powers, Marcela Brissova, Anne Jörns, Sigurd Lenzen, Benjamin Glaser, Knut Dahl-Jørgensen, Yuval Dor

Diabetes 2018;67(11):2305–2318

https://doi.org/10.2337/db17-1006

Published: 27 August 2018

View article titled, β-Cell DNA Damage Response Promotes Islet Inflammation in Type 1 Diabetes

Includes: Supplementary data

Journal Articles

TNF-α Antibody Therapy in Combination With the T-Cell–Specific Antibody Anti-TCR Reverses the Diabetic Metabolic State in the LEW.1AR1-iddm Rat

Anne Jörns, Ümüs Gül Ertekin, Tanja Arndt, Taivankhuu Terbish, Dirk Wedekind, Sigurd Lenzen

Diabetes 2015;64(8):2880–2891

https://doi.org/10.2337/db14-1866

Published: 17 March 2015

View article titled, TNF-α Antibody Therapy in Combination With the T-Cell–Specific Antibody Anti-TCR Reverses the Diabetic Metabolic State in the LEW.1AR1-iddm Rat

Includes: Supplementary data

Journal Articles

Antidiabetic Effect of Interleukin-1β Antibody Therapy Through β-Cell Protection in the Cohen Diabetes-Sensitive Rat

Genya Aharon-Hananel, Anne Jörns, Sigurd Lenzen, Itamar Raz, Sarah Weksler-Zangen

Diabetes 2015;64(5):1780–1785

https://doi.org/10.2337/db14-1018

Published: 08 December 2014

View article titled, Antidiabetic Effect of Interleukin-1β Antibody Therapy Through β-Cell Protection in the Cohen Diabetes-Sensitive Rat

Journal Articles

Peroxisome-Generated Hydrogen Peroxide as Important Mediator of Lipotoxicity in Insulin-Producing Cells

Matthias Elsner, Wiebke Gehrmann, Sigurd Lenzen

Diabetes 2011;60(1):200–208

https://doi.org/10.2337/db09-1401

Published: 22 October 2010

View article titled, Peroxisome-Generated Hydrogen Peroxide as Important Mediator of Lipotoxicity in Insulin-Producing Cells

Includes: Supplementary data

Journal Articles

Impaired Glucose-Stimulated Insulin Secretion Is Coupled With Exocrine Pancreatic Lesions in the Cohen Diabetic Rat

Sarah Weksler-Zangen, Itamar Raz, Sigurd Lenzen, Anne Jörns, Shira Ehrenfeld, Gail Amir, Andrei Oprescu, Yoram Yagil, Chana Yagil, David H. Zangen, Nurit Kaiser

Diabetes 2008;57(2):279–287

https://doi.org/10.2337/db07-0520

Published: 01 February 2008

View article titled, Impaired Glucose-Stimulated Insulin Secretion Is Coupled With Exocrine Pancreatic Lesions in the Cohen Diabetic Rat

Includes: Supplementary data

Journal Articles

Novel Insights Into the Regulation of the Bound and Diffusible Glucokinase in MIN6 β-Cells

Simone Baltrusch, Sigurd Lenzen

Diabetes 2007;56(5):1305–1315

https://doi.org/10.2337/db06-0894

Published: 01 May 2007

View article titled, Novel Insights Into the Regulation of the Bound and Diffusible Glucokinase in MIN6 β-Cells

Journal Articles

Mechanisms of Pancreatic β-Cell Death in Type 1 and Type 2 Diabetes: Many Differences, Few Similarities

Miriam Cnop, Nils Welsh, Jean-Christophe Jonas, Anne Jörns, Sigurd Lenzen, Decio L. Eizirik

Diabetes 2005;54(suppl_2):S97–S107

https://doi.org/10.2337/diabetes.54.suppl_2.S97

Published: 01 December 2005

View article titled, Mechanisms of Pancreatic β-Cell Death in Type 1 and Type 2 Diabetes: <subtitle>Many Differences, Few Similarities</subtitle>

Journal Articles

Interaction of Glucokinase With the Liver Regulatory Protein Is Conferred by Leucine-Asparagine Motifs of the Enzyme

Simone Baltrusch, Flavio Francini, Sigurd Lenzen, Markus Tiedge

Diabetes 2005;54(10):2829–2837

https://doi.org/10.2337/diabetes.54.10.2829

Published: 01 October 2005

View article titled, Interaction of Glucokinase With the Liver Regulatory Protein Is Conferred by Leucine-Asparagine Motifs of the Enzyme

Journal Articles

Immune Cell Infiltration, Cytokine Expression, and β-Cell Apoptosis During the Development of Type 1 Diabetes in the Spontaneously Diabetic LEW.1AR1/Ztm-iddm Rat

Anne Jörns, Armin Günther, Hans-Jürgen Hedrich, Dirk Wedekind, Markus Tiedge, Sigurd Lenzen

Diabetes 2005;54(7):2041–2052

https://doi.org/10.2337/diabetes.54.7.2041

Published: 01 July 2005

View article titled, Immune Cell Infiltration, Cytokine Expression, and β-Cell Apoptosis During the Development of Type 1 Diabetes in the Spontaneously Diabetic LEW.1AR1/Ztm-iddm Rat

Journal Articles

Mitochondrial Catalase Overexpression Protects Insulin-Producing Cells Against Toxicity of Reactive Oxygen Species and Proinflammatory Cytokines

Ewa Gurgul, Stephan Lortz, Markus Tiedge, Anne Jörns, Sigurd Lenzen

Diabetes 2004;53(9):2271–2280

https://doi.org/10.2337/diabetes.53.9.2271

Published: 01 September 2004

View article titled, Mitochondrial Catalase Overexpression Protects Insulin-Producing Cells Against Toxicity of Reactive Oxygen Species and Proinflammatory Cytokines

Journal Articles

Interaction of 6-Phosphofructo-2-Kinase/Fructose-2,6-Bisphosphatase (PFK-2/FBPase-2) With Glucokinase Activates Glucose Phosphorylation and Glucose Metabolism in Insulin-Producing Cells

Laura Massa, Simone Baltrusch, David A. Okar, Alex J. Lange, Sigurd Lenzen, Markus Tiedge

Diabetes 2004;53(4):1020–1029

https://doi.org/10.2337/diabetes.53.4.1020

Published: 01 April 2004

View article titled, Interaction of 6-Phosphofructo-2-Kinase/Fructose-2,6-Bisphosphatase (PFK-2/FBPase-2) With Glucokinase Activates Glucose Phosphorylation and Glucose Metabolism in Insulin-Producing Cells

Journal Articles

Improvement of the Mitochondrial Antioxidant Defense Status Prevents Cytokine-Induced Nuclear Factor-κB Activation in Insulin-Producing Cells

Anna Karenina Azevedo-Martins, Stephan Lortz, Sigurd Lenzen, Rui Curi, Decio L. Eizirik, Markus Tiedge

Diabetes 2003;52(1):93–101

https://doi.org/10.2337/diabetes.52.1.93

Published: 01 January 2003

View article titled, Improvement of the Mitochondrial Antioxidant Defense Status Prevents Cytokine-Induced Nuclear Factor-κB Activation in Insulin-Producing Cells

Journal Articles

Relation Between Antioxidant Enzyme Gene Expression and Antioxidative Defense Status of Insulin-Producing Cells

Markus Tiedge, Stephan Lortz, Jens Drinkgern, Sigurd Lenzen

Diabetes 1997;46(11):1733–1742

https://doi.org/10.2337/diab.46.11.1733

Published: 01 November 1997

View article titled, Relation Between Antioxidant Enzyme Gene Expression and Antioxidative Defense Status of Insulin-Producing Cells

Journal Articles

Effects of IP₃, Spermine, and Mg²⁺ on Regulation of Ca²⁺ Transport by Endoplasmic Reticulum and Mitochondria in Permeabilized Pancreatic Islets

Sigurd Lenzen, Ingo Rustenbeck

Diabetes 1991;40(3):323–326

https://doi.org/10.2337/diab.40.3.323

Published: 01 March 1991

View article titled, Effects of IP3, Spermine, and Mg2+ on Regulation of Ca2+ Transport by Endoplasmic Reticulum and Mitochondria in Permeabilized Pancreatic Islets

Journal Articles

The Immediate Insulin-secretory Response of the Rat Pancreas to Glucose Compared with Tolbutamide and Other Secretagogues

Sigurd Lenzen, MD

Diabetes 1978;27(1):27–34

https://doi.org/10.2337/diab.27.1.27

Published: 01 January 1978

View article titled, The Immediate Insulin-secretory Response of the Rat Pancreas to Glucose Compared with Tolbutamide and Other Secretagogues

NARROW

PNLIPRP1 hypermethylation in exocrine pancreas links type 2 diabetes and cholesterol metabolism

Pancreas Pathology of Latent Autoimmune Diabetes in Adults (LADA) in Patients and in a LADA Rat Model Compared With Type 1 Diabetes

β-Cell DNA Damage Response Promotes Islet Inflammation in Type 1 Diabetes

TNF-α Antibody Therapy in Combination With the T-Cell–Specific Antibody Anti-TCR Reverses the Diabetic Metabolic State in the LEW.1AR1-iddm Rat

Antidiabetic Effect of Interleukin-1β Antibody Therapy Through β-Cell Protection in the Cohen Diabetes-Sensitive Rat

Peroxisome-Generated Hydrogen Peroxide as Important Mediator of Lipotoxicity in Insulin-Producing Cells

Impaired Glucose-Stimulated Insulin Secretion Is Coupled With Exocrine Pancreatic Lesions in the Cohen Diabetic Rat

Novel Insights Into the Regulation of the Bound and Diffusible Glucokinase in MIN6 β-Cells

Mechanisms of Pancreatic β-Cell Death in Type 1 and Type 2 Diabetes: Many Differences, Few Similarities

Interaction of Glucokinase With the Liver Regulatory Protein Is Conferred by Leucine-Asparagine Motifs of the Enzyme

Immune Cell Infiltration, Cytokine Expression, and β-Cell Apoptosis During the Development of Type 1 Diabetes in the Spontaneously Diabetic LEW.1AR1/Ztm-iddm Rat

Mitochondrial Catalase Overexpression Protects Insulin-Producing Cells Against Toxicity of Reactive Oxygen Species and Proinflammatory Cytokines

Interaction of 6-Phosphofructo-2-Kinase/Fructose-2,6-Bisphosphatase (PFK-2/FBPase-2) With Glucokinase Activates Glucose Phosphorylation and Glucose Metabolism in Insulin-Producing Cells

Improvement of the Mitochondrial Antioxidant Defense Status Prevents Cytokine-Induced Nuclear Factor-κB Activation in Insulin-Producing Cells

Relation Between Antioxidant Enzyme Gene Expression and Antioxidative Defense Status of Insulin-Producing Cells

Effects of IP₃, Spermine, and Mg²⁺ on Regulation of Ca²⁺ Transport by Endoplasmic Reticulum and Mitochondria in Permeabilized Pancreatic Islets

The Immediate Insulin-secretory Response of the Rat Pancreas to Glucose Compared with Tolbutamide and Other Secretagogues

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