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Silva A. Arslanian
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Meeting Abstracts

133-OR: Insulin Dynamics across the Glucose Tolerance Spectrum in Youth with Obesity

WONHEE CHO, FIDA BACHA, HALA M. TFAYLI, SOJUNG LEE, SARA MICHALISZYN, JOON YOUNG KIM, SILVA A. ARSLANIAN
Journal: Diabetes
Diabetes 2023;72(Supplement_1):133-OR
https://doi.org/10.2337/db23-133-OR
Published: 20 June 2023
View article titled, 133-OR: Insulin Dynamics across the Glucose Tolerance Spectrum in Youth with Obesity
Meeting Abstracts

1091-P: Genetic Ancestry Influences Metformin Treatment Response in Youth with Type 2 Diabetes

SHYLAJA SRINIVASAN, LING CHEN, MEGAN M. KELSEY, JENNIFER TODD, SILVA A. ARSLANIAN, NANCY T. CHANG, LORI M. LAFFEL, LYNNE L. LEVITSKY, JENNIFER E. SPRAGUE, TONI I. POLLIN, ALISA MANNING, JOSE C. FLOREZ
Journal: Diabetes
Diabetes 2023;72(Supplement_1):1091-P
https://doi.org/10.2337/db23-1091-P
Published: 20 June 2023
View article titled, 1091-P: Genetic Ancestry Influences Metformin Treatment Response in Youth with Type 2 Diabetes
Meeting Abstracts

1108-P: Physical Activity in Adolescents and Young Adults (AYA) with Type 2 Diabetes (T2D) or Prediabetes—The Role of Motivation

MARY ELLEN VAJRAVELU, ADRIANA RODRIGUEZ GONZALEZ, BRIANNA HEWITT, ANDREA KRISKA, JONATHAN MITCHELL, VICKI HELGESON, SANDRA AMARAL, SILVA A. ARSLANIAN
Journal: Diabetes
Diabetes 2023;72(Supplement_1):1108-P
https://doi.org/10.2337/db23-1108-P
Published: 20 June 2023
View article titled, 1108-P: Physical Activity in Adolescents and Young Adults (AYA) with Type 2 Diabetes (T2D) or Prediabetes—The Role of Motivation
Meeting Abstracts

346-OR: Race/Ethnicity-Specific Relationships of Physical Markers of Adiposity to Clamp-Measured Insulin Sensitivity (IS) and ß-Cell Function (ßCF) in Obese Youth

JARED ROSENBERG, WONHEE CHO, SILVA A. ARSLANIAN, JOON YOUNG KIM
Journal: Diabetes
Diabetes 2022;71(Supplement_1):346-OR
https://doi.org/10.2337/db22-346-OR
Published: 01 June 2022
View article titled, 346-OR: Race/Ethnicity-Specific Relationships of Physical Markers of Adiposity to Clamp-Measured Insulin Sensitivity (IS) and ß-Cell Function (ßCF) in Obese Youth
Meeting Abstracts

1044-P: Impact of Pregnancy on Microvascular and Cardiac Outcomes in Youth-Onset Type 2 Diabetes

JEANIE B. TRYGGESTAD, MEGAN M. KELSEY, SILVA A. ARSLANIAN, STEVEN CHERNAUSEK, KIMBERLY DREWS, ELIA N. ESCANAME, MITCHELL GEFFNER, ELVIRA M. ISGANAITIS
Journal: Diabetes
Diabetes 2022;71(Supplement_1):1044-P
https://doi.org/10.2337/db22-1044-P
Published: 01 June 2022
View article titled, 1044-P: Impact of Pregnancy on Microvascular and Cardiac Outcomes in Youth-Onset Type 2 Diabetes
Meeting Abstracts

143-LB: Hepatic Insulin Resistance Index (HIR-I) in Youth—Does Race/Ethnicity Matter?

WONHEE CHO, FIDA BACHA, HALA M. TFAYLI, SOJUNG LEE, SARA MICHALISZYN, JOON YOUNG KIM, SILVA A. ARSLANIAN
Journal: Diabetes
Diabetes 2022;71(Supplement_1):143-LB
https://doi.org/10.2337/db22-143-LB
Published: 01 June 2022
View article titled, 143-LB: Hepatic Insulin Resistance Index (HIR-I) in Youth—Does Race/Ethnicity Matter?
Meeting Abstracts

341-OR: Enhanced Responsiveness of ß- and α-Cells to Glucagon-Like Peptide-1 (GLP-1) in Youth vs. Adults with Impaired Glucose Tolerance (IGT) or Drug-Naïve Type 2 Diabetes (T2D)

KRISTEN J. NADEAU, ASHLEY H. TJADEN, DAVID A. EHRMANN, SILVA A. ARSLANIAN, SONIA CAPRIO, SHARON EDELSTEIN, TAMARA S. HANNON, KARLA A. TEMPLE, ANNY XIANG, STEVEN E. KAHN, THE RISE CONSORTIUM
Journal: Diabetes
Diabetes 2022;71(Supplement_1):341-OR
https://doi.org/10.2337/db22-341-OR
Published: 01 June 2022
View article titled, 341-OR: Enhanced Responsiveness of ß- and α-Cells to Glucagon-Like Peptide-1 (GLP-1) in Youth vs. Adults with Impaired Glucose Tolerance (IGT) or Drug-Naïve Type 2 Diabetes (T2D)
Meeting Abstracts

5-LB: Dulaglutide in Youth with Type 2 Diabetes (T2D) —Results of the AWARD-PEDS Randomized, Placebo-Controlled Trial

SILVA A. ARSLANIAN, JANG IK CHO, TAMARA S. HANNON, PHILIP ZEITLER, LILY CHAO, MARGARITA BARRIENTOS, CLAUDIA C. BOUCHER-BERRY, ELISE BISMUTH, SERGIO A. DIB, DAVID COX
Journal: Diabetes
Diabetes 2022;71(Supplement_1):5-LB
https://doi.org/10.2337/db22-5-LB
Published: 01 June 2022
View article titled, 5-LB: Dulaglutide in Youth with Type 2 Diabetes (T2D) —Results of the AWARD-PEDS Randomized, Placebo-Controlled Trial
Meeting Abstracts

361-OR: Proinsulin Processing Efficiency Differs in Youth and Adults with IGT or Untreated T2D

TAMARA S. HANNON, SUSAN SAM, ASHLEY H. TJADEN, SHARON EDELSTEIN, KRISTEN J. NADEAU, SILVA A. ARSLANIAN, MELANIE CREE-GREEN, DAVID A. EHRMANN, KIEREN J. MATHER, STEVEN E. KAHN, THE RISE CONSORTIUM
Journal: Diabetes
Diabetes 2022;71(Supplement_1):361-OR
https://doi.org/10.2337/db22-361-OR
Published: 01 June 2022
View article titled, 361-OR: Proinsulin Processing Efficiency Differs in Youth and Adults with IGT or Untreated T2D
Meeting Abstracts

1296-P: Adipose Tissue Insulin Resistance in RISE: Divergence between Youth and Adults, and Females and Males

SILVA A. ARSLANIAN, SONIA CAPRIO, KRISTEN J. NADEAU, KARLA A. TEMPLE, PANDORA WANDER, MELANIE CREE-GREEN, TAMARA S. HANNON, STEVEN E. KAHN, LAURE EL GHORMLI, THE RISE CONSORTIUM
Journal: Diabetes
Diabetes 2022;71(Supplement_1):1296-P
https://doi.org/10.2337/db22-1296-P
Published: 01 June 2022
View article titled, 1296-P: Adipose Tissue Insulin Resistance in RISE: Divergence between Youth and Adults, and Females and Males
Meeting Abstracts

17-OR: Mathematical Model Disposition Index (mDI) Predicts Dysglycemia in Obese Youth

JOON HA, JOON YOUNG KIM, ARTHUR SHERMAN, SILVA A. ARSLANIAN
Journal: Diabetes
Diabetes 2021;70(Supplement_1):17-OR
https://doi.org/10.2337/db21-17-OR
Published: 01 June 2021
View article titled, 17-OR: Mathematical Model Disposition Index (mDI) Predicts Dysglycemia in Obese Youth
Meeting Abstracts

18-OR: Longitudinal Changes in Vascular Stiffness and Heart Rate Variability (HRV) in Young Adults with Type 2 Diabetes (T2D): The TODAY Study

AMY S. SHAH, LAURE EL GHORMLI, SAMUEL GIDDING, KARA S. HUGHAN, LORRAINE E. KATZ, DORIT KOREN, JEANIE B. TRYGGESTAD, FIDA BACHA, BARBARA H. BRAFFETT, SILVA A. ARSLANIAN, ELAINE M. URBINA
Journal: Diabetes
Diabetes 2021;70(Supplement_1):18-OR
https://doi.org/10.2337/db21-18-OR
Published: 01 June 2021
View article titled, 18-OR: Longitudinal Changes in Vascular Stiffness and Heart Rate Variability (HRV) in Young Adults with Type 2 Diabetes (T2D): The TODAY Study
Meeting Abstracts

152-LB: Homeostatic Model Assessment of Adiponectin (HOMA-AD) in Youth across the Spectrum of Adiposity and along the Span of Glycemia

JORDAN JACOB, JOON YOUNG KIM, SILVA A. ARSLANIAN
Journal: Diabetes
Diabetes 2021;70(Supplement_1):152-LB
https://doi.org/10.2337/db21-152-LB
Published: 01 June 2021
View article titled, 152-LB: Homeostatic Model Assessment of Adiponectin (HOMA-AD) in Youth across the Spectrum of Adiposity and along the Span of Glycemia
Meeting Abstracts

1794-P: Successful Standardization of a Hyperglycemic Clamp Method across Multiple Clinical Centers in the Restoring Insulin Secretion (RISE) Study

KIEREN J. MATHER, ASHLEY H. TJADEN, SILVA A. ARSLANIAN, KRISTINA UTZSCHNEIDER, SONIA CAPRIO, KRISTINA UTZSCHNEIDER, KAREN M. ATKINSON, MELANIE CREE-GREEN, KRISTEN J. NADEAU, THOMAS A. BUCHANAN, STEVEN E. KAHN, THE RISE CONSORTIUM
Journal: Diabetes
Diabetes 2020;69(Supplement_1):1794-P
https://doi.org/10.2337/db20-1794-P
Published: 01 June 2020
View article titled, 1794-P: Successful Standardization of a Hyperglycemic Clamp Method across Multiple Clinical Centers in the Restoring Insulin Secretion (RISE) Study
Meeting Abstracts

1782-P: Impact of Treatment with Medication vs. Laparoscopic Gastric Banding (GB) on ß-Cell Function in Adults with Impaired Glucose Tolerance (IGT) or Type 2 Diabetes (T2D) in the Restoring Insulin Secretion (RISE) Study

DAVID A. EHRMANN, SHARON EDELSTEIN, ANNY XIANG, THOMAS A. BUCHANAN, SILVA A. ARSLANIAN, SONIA CAPRIO, KIEREN J. MATHER, KRISTEN J. NADEAU, STEVEN E. KAHN, THE RISE CONSORTIUM
Journal: Diabetes
Diabetes 2020;69(Supplement_1):1782-P
https://doi.org/10.2337/db20-1782-P
Published: 01 June 2020
View article titled, 1782-P: Impact of Treatment with Medication vs. Laparoscopic Gastric Banding (GB) on ß-Cell Function in Adults with Impaired Glucose Tolerance (IGT) or Type 2 Diabetes (T2D) in the Restoring Insulin Secretion (RISE) Study
Meeting Abstracts

60-OR: OGTT Glucose Response Curves (GRC), Insulin Sensitivity (IS), and ß-Cell Function (ßCF) in RISE: Youth–Adult Contrast at Randomization and in Response to Interventions to Preserve ßCF

SILVA A. ARSLANIAN, LAURE EL GHORMLI, JOON YOUNG KIM, TAMARA S. HANNON, KIEREN J. MATHER, SONIA CAPRIO, ELENA BARENGOLTS, KRISTEN J. NADEAU, KRISTINA UTZSCHNEIDER, STEVEN E. KAHN, THE RISE CONSORTIUM
Journal: Diabetes
Diabetes 2020;69(Supplement_1):60-OR
https://doi.org/10.2337/db20-60-OR
Published: 01 June 2020
View article titled, 60-OR: OGTT Glucose Response Curves (GRC), Insulin Sensitivity (IS), and ß-Cell Function (ßCF) in RISE: Youth–Adult Contrast at Randomization and in Response to Interventions to Preserve ßCF
Meeting Abstracts

56-OR: Degree of ß-Cell Function (ßCF) Impairment and Glycemic Alterations in Obese Youth (OY) Spanning from Normal Glucose Tolerance (NGT) to Impaired Glucose Tolerance (IGT) to Type 2 Diabetes (T2D): Does Race Matter?

JOON YOUNG KIM, HALA M. TFAYLI, FIDA BACHA, NOUR GEBARA, SILVA A. ARSLANIAN
Journal: Diabetes
Diabetes 2020;69(Supplement_1):56-OR
https://doi.org/10.2337/db20-56-OR
Published: 01 June 2020
View article titled, 56-OR: Degree of ß-Cell Function (ßCF) Impairment and Glycemic Alterations in Obese Youth (OY) Spanning from Normal Glucose Tolerance (NGT) to Impaired Glucose Tolerance (IGT) to Type 2 Diabetes (T2D): Does Race Matter?
Meeting Abstracts

1679-P: Islet Autoimmunity in Adults with Impaired Glucose Tolerance (IGT) and Newly Diagnosed, Treatment-Naïve Type 2 Diabetes (NDX T2D) in the Restoring Insulin Secretion (RISE) Study

BARBARA BROOKS-WORRELL, ASHLEY H. TJADEN, SHARON EDELSTEIN, BRENDA M. PALOMINO, KRISTINA UTZSCHNEIDER, SILVA A. ARSLANIAN, KIEREN J. MATHER, THOMAS A. BUCHANAN, KRISTEN J. NADEAU, KAREN M. ATKINSON, ELENA BARENGOLTS, STEVEN E. KAHN, JERRY P. PALMER, RISE CONSORTIUM
Journal: Diabetes
Diabetes 2020;69(Supplement_1):1679-P
https://doi.org/10.2337/db20-1679-P
Published: 01 June 2020
View article titled, 1679-P: Islet Autoimmunity in Adults with Impaired Glucose Tolerance (IGT) and Newly Diagnosed, Treatment-Naïve Type 2 Diabetes (NDX T2D) in the Restoring Insulin Secretion (RISE) Study
Meeting Abstracts

1268-P: Associations between ß-Cell Function and Cognitive Measures following Treatment in Youth with Impaired Glucose Tolerance (IGT) or Recently Diagnosed Type 2 Diabetes (T2D)

SUZANNE CRAFT, MARK TRIPPUTI, SHARON EDELSTEIN, MARK ESPELAND, AMY CLAXTON, SILVA A. ARSLANIAN, ELENA BARENGOLTS, TAMARA S. HANNON, STEVEN E. KAHN, KIEREN J. MATHER, BABAK MOKHLESI, KRISTEN J. NADEAU, ASHLEY SANDERLIN, KARLA A. TEMPLE, PHILIP ZEITLER, THE RISE CONSORTIUM
Journal: Diabetes
Diabetes 2020;69(Supplement_1):1268-P
https://doi.org/10.2337/db20-1268-P
Published: 01 June 2020
View article titled, 1268-P: Associations between ß-Cell Function and Cognitive Measures following Treatment in Youth with Impaired Glucose Tolerance (IGT) or Recently Diagnosed Type 2 Diabetes (T2D)
Journal Articles

Effects of Treatment of Impaired Glucose Tolerance or Recently Diagnosed Type 2 Diabetes With Metformin Alone or in Combination With Insulin Glargine on β-Cell Function: Comparison of Responses In Youth And Adults

RISE Consortium Investigators, David A. Ehrmann, Karla A. Temple, Abby Rue, Elena Barengolts, Babak Mokhlesi, Eve Van Cauter, Susan Sam, M. Annette Miller, Steven E. Kahn, Karen M. Atkinson, Jerry P. Palmer, Kristina M. Utzschneider, Tsige Gebremedhin, Abigail Kernan-Schloss, Alexandra Kozedub, Brenda K. Montgomery, Emily J. Morse, Kieren J. Mather, Tammy Garrett, Tamara S. Hannon, Amale Lteif, Aniket Patel, Robin Chisholm, Karen Moore, Vivian Pirics, Linda Pratt, Kristen J. Nadeau, Susan Gross, Philip S. Zeitler, Jayne Williams, Melanie Cree-Green, Yesenia Garcia Reyes, Krista Vissat, Silva A. Arslanian, Kathleen Brown, Nancy Guerra, Kristin Porter, Sonia Caprio, Mary Savoye, Bridget Pierpont, Thomas A. Buchanan, Anny H. Xiang, Enrique Trigo, Elizabeth Beale, Ting Chow, Fadi N. Hendee, Namir Katkhouda, Krishan Nayak, Mayra Martinez, Cortney Montgomery, Xinhui Wang, Jun Wu, Sharon L. Edelstein, John M. Lachin, Ashley Hogan Tjaden, Mark T. Tripputi, Santica Marcovina, Jessica Harting, John Albers, Dave Hill, Peter J. Savage, Ellen W. Leschek
Journal: Diabetes
Diabetes 2019;68(8):1670–1680
https://doi.org/10.2337/db19-0299
Published: 09 June 2019
View article titled, Effects of Treatment of Impaired Glucose Tolerance or Recently Diagnosed Type 2 Diabetes With Metformin Alone or in Combination With Insulin Glargine on β-Cell Function: Comparison of Responses In Youth And Adults
Open the PDF for Effects of Treatment of Impaired Glucose Tolerance or Recently Diagnosed Type 2 Diabetes With Metformin Alone or in Combination With Insulin Glargine on β-Cell Function: Comparison of Responses In Youth And Adults in another window
Includes: Supplementary data