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Meeting Abstracts

1666-P: Effect of Obesity in Family History (FH) on the Prevalence of Type 2 Diabetes Mellitus (T2DM), Hypertension (HT), and Dyslipidemia (DL)

IZUMI IKEDA, KAZUYA FUJIHARA, YASUNAGA TAKEDA, CHIKA HORIKAWA, SATORU KODAMA, EFREM D. FERREIRA, YASUMICHI MORI, TAKASHI KADOWAKI, RITSUKO YAMAMOTO-HONDA, YASUJI ARASE, HIROHITO SONE

Diabetes 2024;73(Supplement_1):1666-P

https://doi.org/10.2337/db24-1666-P

Published: 14 June 2024

View article titled, 1666-P: Effect of Obesity in Family History (FH) on the Prevalence of Type 2 Diabetes Mellitus (T2DM), Hypertension (HT), and Dyslipidemia (DL)

Meeting Abstracts

1474-P: Cross-Sectional and Longitudinal Relationships between Detailed Family History (FH) of Type 2 Diabetes Mellitus (T2DM), Hypertension (HT), and Dyslipidemia (DL) and Prevalence of Each Disorder

IZUMI IKEDA, KAZUYA FUJIHARA, YASUNAGA TAKEDA, MARIKO HATTA, SIJIA WU, SATORU KODAMA, YASUMICHI MORI, TAKASHI KADOWAKI, RITSUKO YAMAMOTO-HONDA, YASUJI ARASE, HIROHITO SONE

Diabetes 2024;73(Supplement_1):1474-P

https://doi.org/10.2337/db24-1474-P

Published: 14 June 2024

View article titled, 1474-P: Cross-Sectional and Longitudinal Relationships between Detailed Family History (FH) of Type 2 Diabetes Mellitus (T2DM), Hypertension (HT), and Dyslipidemia (DL) and Prevalence of Each Disorder

Journal Articles

Overexpression of UBE2E2 in Mouse Pancreatic β-Cells Leads to Glucose Intolerance via Reduction of β-Cell Mass

Yoshitaka Sakurai, Naoto Kubota, Iseki Takamoto, Nobuhiro Wada, Masakazu Aihara, Takanori Hayashi, Tetsuya Kubota, Yuta Hiraike, Takayoshi Sasako, Harumi Nakao, Atsu Aiba, Yoko Chikaoka, Takeshi Kawamura, Takashi Kadowaki, Toshimasa Yamauchi

Diabetes 2024;73(3):474–489

https://doi.org/10.2337/db23-0150

Published: 08 December 2023

View article titled, Overexpression of UBE2E2 in Mouse Pancreatic β-Cells Leads to Glucose Intolerance via Reduction of β-Cell Mass

Journal Articles

Genotype-Structure-Phenotype Correlations of Disease-Associated IGF1R Variants and Similarities to Those of INSR Variants

Jun Hosoe, Yuki Kawashima-Sonoyama, Fuyuki Miya, Hiroko Kadowaki, Ken Suzuki, Takashi Kato, Fumiko Matsuzawa, Sei-Ichi Aikawa, Yukinori Okada, Tatsuhiko Tsunoda, Keiichi Hanaki, Susumu Kanzaki, Nobuhiro Shojima, Toshimasa Yamauchi, Takashi Kadowaki

Diabetes 2021;70(8):1874–1884

https://doi.org/10.2337/db20-1145

Published: 01 June 2021

View article titled, Genotype-Structure-Phenotype Correlations of Disease-Associated IGF1R Variants and Similarities to Those of INSR Variants

Meeting Abstracts

607-P: Glycemic Metrics in Japanese Flash Glucose Monitoring Users by Diabetes Type and Therapy

WATARU OGAWA, TATSUHIKO URAKAMI, TAKASHI KADOWAKI, KALVIN KAO, LAURA BRANDNER, KENICHIRO SHIMIZU, TIMOTHY DUNN

Diabetes 2021;70(Supplement_1):607-P

https://doi.org/10.2337/db21-607-P

Published: 01 June 2021

View article titled, 607-P: Glycemic Metrics in Japanese Flash Glucose Monitoring Users by Diabetes Type and Therapy

Meeting Abstracts

1086-P: A Retrospective Nationwide Surveillance on the First-Line Antidiabetic Medication for the Patients with Type 2 Diabetes in Japan

RYOTARO BOUCHI, TAKEHIRO SUGIYAMA, ATSUSHI GOTO, KENJIRO IMAI, NORIKO IHANA-SUGIYAMA, MITSURU OHSUGI, TOSHIMASA YAMAUCHI, TAKASHI KADOWAKI, KOHJIRO UEKI

Diabetes 2021;70(Supplement_1):1086-P

https://doi.org/10.2337/db21-1086-P

Published: 01 June 2021

View article titled, 1086-P: A Retrospective Nationwide Surveillance on the First-Line Antidiabetic Medication for the Patients with Type 2 Diabetes in Japan

Journal Articles

Lack of Brain Insulin Receptor Substrate-1 Causes Growth Retardation, With Decreased Expression of Growth Hormone–Releasing Hormone in the Hypothalamus

Takanori Hayashi, Tetsuya Kubota, Inoue Mariko, Iseki Takamoto, Masakazu Aihara, Yoshitaka Sakurai, Nobuhiro Wada, Takashi Miki, Toshimasa Yamauchi, Naoto Kubota, Takashi Kadowaki

Diabetes 2021;70(8):1640–1653

https://doi.org/10.2337/db20-0482

Published: 12 May 2021

View article titled, Lack of Brain Insulin Receptor Substrate-1 Causes Growth Retardation, With Decreased Expression of Growth Hormone–Releasing Hormone in the Hypothalamus

Meeting Abstracts

926-P: Cardiovascular (CV) and Hypoglycemia Outcomes across Age Groups in People with Type 2 Diabetes (T2D) in the CAROLINA Trial

MARK ESPELAND, RICHARD E. PRATLEY, JULIO ROSENSTOCK, TAKASHI KADOWAKI, YUTAKA SEINO, BERNARD ZINMAN, NIKOLAUS MARX, DARREN K. MCGUIRE, KNUT R. ANDERSEN, MICHAELA MATTHEUS, ANNETT KELLER, ODD ERIK JOHANSEN

Diabetes 2020;69(Supplement_1):926-P

https://doi.org/10.2337/db20-926-P

Published: 01 June 2020

View article titled, 926-P: Cardiovascular (CV) and Hypoglycemia Outcomes across Age Groups in People with Type 2 Diabetes (T2D) in the CAROLINA Trial

Meeting Abstracts

887-P: Development of the Noninvasive Diabetes Monitoring Method

MASAKAZU AIHARA, NAOTO KUBOTA, TAKASHI KADOWAKI

Diabetes 2020;69(Supplement_1):887-P

https://doi.org/10.2337/db20-887-P

Published: 01 June 2020

View article titled, 887-P: Development of the Noninvasive Diabetes Monitoring Method

Meeting Abstracts

1876-P: Gut Microbial Fermentation of Polysaccharides Impacts Insulin Resistance in Humans

TADASHI TAKEUCHI, YUMIKO NAKANISHI, KAZUTAKA IKEDA, HIROSHI TSUGAWA, WATARU SUDA, YOSHIKO MIZUNO, NOBUTAKE YAMAMICHI, MAKOTO ARITA, MASAHIRA HATTORI, NAOTO KUBOTA, TETSUYA KUBOTA, TAKASHI KADOWAKI, SHIGEO KOYASU, HIROSHI OHNO

Diabetes 2020;69(Supplement_1):1876-P

https://doi.org/10.2337/db20-1876-P

Published: 01 June 2020

View article titled, 1876-P: Gut Microbial Fermentation of Polysaccharides Impacts Insulin Resistance in Humans

Meeting Abstracts

1697-P: NFIA Differentially Regulates Adipogenesis and Myogenesis through Distinct Molecular Pathways to Ensure Adipocyte Differentiation

YUTA HIRAIKE, HIRONORI WAKI, KANA MIYAKE, MISATO OGUCHI, TOSHIMASA YAMAUCHI, TAKASHI KADOWAKI

Diabetes 2020;69(Supplement_1):1697-P

https://doi.org/10.2337/db20-1697-P

Published: 01 June 2020

View article titled, 1697-P: NFIA Differentially Regulates Adipogenesis and Myogenesis through Distinct Molecular Pathways to Ensure Adipocyte Differentiation

Meeting Abstracts

1741-P: Immune Regulation of Postprandial Glycemia and Whole-Body Insulin Sensitivity through Myeloid Production of IL-10

GOTARO TODA, KOTARO SOEDA, NAOKO ARAKAWA, YUKARI MASUDA, NAOKI KOBAYASHI, HIROTSUGU SUWANAI, YOSHIHIKO IZUMIDA, TOSHIMASA YAMAUCHI, TAKASHI KADOWAKI, KOHJIRO UEKI

Diabetes 2020;69(Supplement_1):1741-P

https://doi.org/10.2337/db20-1741-P

Published: 01 June 2020

View article titled, 1741-P: Immune Regulation of Postprandial Glycemia and Whole-Body Insulin Sensitivity through Myeloid Production of IL-10

Meeting Abstracts

55-OR: Oral Semaglutide vs. Liraglutide and Placebo in T2D: PIONEER 4

RICHARD E. PRATLEY, ASLAM AMOD, SOREN T. HOFF, TAKASHI KADOWAKI, ILDIKO LINGVAY, MICHAEL A. NAUCK, KAREN BOJE PEDERSEN, TRINE SAUGSTRUP, JURIS J. MEIER, FOR THE PIONEER 4 INVESTIGATORS

Diabetes 2019;68(Supplement_1):55-OR

https://doi.org/10.2337/db19-55-OR

Published: 01 June 2019

View article titled, 55-OR: Oral Semaglutide vs. Liraglutide and Placebo in T2D: PIONEER 4

Meeting Abstracts

1325-P: Effectiveness of Comprehensive Gene Panel-Based Next-Generation Sequencing with Phenotype-Driven Bioinformatics Analysis for Diagnosis of Atypical Diabetes

JUN HOSOE, HIROKO KADOWAKI, FUYUKI MIYA, MINAKA TAKAKURA, HIRONORI WAKI, TAKAYOSHI SASAKO, TAKASHI KATO, TATSUHIKO TSUNODA, NOBUHIRO SHOJIMA, TOSHIMASA YAMAUCHI, TAKASHI KADOWAKI

Diabetes 2019;68(Supplement_1):1325-P

https://doi.org/10.2337/db19-1325-P

Published: 01 June 2019

View article titled, 1325-P: Effectiveness of Comprehensive Gene Panel-Based Next-Generation Sequencing with Phenotype-Driven Bioinformatics Analysis for Diagnosis of Atypical Diabetes

Meeting Abstracts

206-LB: Cardiorenal Disease Is the Most Common First CV Manifestation in Type 2 Diabetes and Associated with Increased Mortality: A Large Multinational Observational Study

KARE I. BIRKELAND, JOHAN BODEGARD, MARCUS THURESSON, JAN W. ERIKSSON, ANNA NORHAMMAR, TOSHITAKA YAJIMA, ISSEI KOMURO, TAKASHI KADOWAKI

Diabetes 2019;68(Supplement_1):206-LB

https://doi.org/10.2337/db19-206-LB

Published: 01 June 2019

View article titled, 206-LB: Cardiorenal Disease Is the Most Common First CV Manifestation in Type 2 Diabetes and Associated with Increased Mortality: A Large Multinational Observational Study

Meeting Abstracts

Efficacy and Safety of Faster Aspart Compared with Insulin Aspart Both with Insulin Degludec in Adults with T1D

JOHN B. BUSE, ANDERS CARLSON, MITSUHISA KOMATSU, OFRI MOSENZON, LUDGER ROSE, BO LIANG, HIROSHI HORIO, TAKASHI KADOWAKI

Diabetes 2018;67(Supplement_1):1000-P

https://doi.org/10.2337/db18-1000-P

Published: 01 July 2018

View article titled, Efficacy and Safety of Faster Aspart Compared with Insulin Aspart Both with Insulin Degludec in Adults with T1D

Meeting Abstracts

Study of the Correlation between Tear Glucose Concentrations and Blood Glucose Concentrations

MASAKAZU AIHARA, NAOTO KUBOTA, TAKASHI KADOWAKI

Diabetes 2018;67(Supplement_1):944-P

https://doi.org/10.2337/db18-944-P

Published: 01 July 2018

View article titled, Study of the Correlation between Tear Glucose Concentrations and Blood Glucose Concentrations

Meeting Abstracts

Impairment of M2a-Subtype Macrophage Activation by Il-4-Irs2 Pathway in Obesity

TETSUYA KUBOTA, MARIKO INOUE, NAOTO KUBOTA, ISEKI TAKAMOTO, KOHJIRO UEKI, TOSHIMASA YAMAUCHI, TAKASHI KADOWAKI

Diabetes 2018;67(Supplement_1):2012-P

https://doi.org/10.2337/db18-2012-P

Published: 01 July 2018

View article titled, Impairment of M2a-Subtype Macrophage Activation by Il-4-Irs2 Pathway in Obesity

Meeting Abstracts

Macrophages React to Postprandial Signals and Regulate the Response to Feeding through Akt-mTOR–Dependent Production of IL-10

GOTARO TODA, NOZOMU KAMEI, KOTARO SOEDA, YUKARI MASUDA, YOSHIHIKO IZUMIDA, NAOKI KOBAYASHI, TAKAYOSI SASAKO, KAZUYUKI TOBE, MORRIS J. BIRNBAUM, TAKASHI KADOWAKI, KOHJIRO UEKI

Diabetes 2018;67(Supplement_1):359-OR

https://doi.org/10.2337/db18-359-OR

Published: 01 July 2018

View article titled, Macrophages React to Postprandial Signals and Regulate the Response to Feeding through Akt-mTOR–Dependent Production of IL-10

Meeting Abstracts

Tofogliflozin Suppresses the Progression of Atherosclerosis and Reduces Inflammation in Macrophages of STZ-Diabetic ApoE KO Mice due to Improvement of Glucose Tolerance

MASAHIKO IWAMOTO, NAOTO KUBOTA, TETSUYA KUBOTA, YOSHITAKA SAKURAI, NOBUHIRO WADA, ISEKI TAKAMOTO, SEIJI SHIODA, TAKASHI KADOWAKI

Diabetes 2018;67(Supplement_1):486-P

https://doi.org/10.2337/db18-486-P

Published: 01 July 2018

View article titled, Tofogliflozin Suppresses the Progression of Atherosclerosis and Reduces Inflammation in Macrophages of STZ-Diabetic ApoE KO Mice due to Improvement of Glucose Tolerance

NARROW

1666-P: Effect of Obesity in Family History (FH) on the Prevalence of Type 2 Diabetes Mellitus (T2DM), Hypertension (HT), and Dyslipidemia (DL)

1474-P: Cross-Sectional and Longitudinal Relationships between Detailed Family History (FH) of Type 2 Diabetes Mellitus (T2DM), Hypertension (HT), and Dyslipidemia (DL) and Prevalence of Each Disorder

Overexpression of UBE2E2 in Mouse Pancreatic β-Cells Leads to Glucose Intolerance via Reduction of β-Cell Mass

Genotype-Structure-Phenotype Correlations of Disease-Associated IGF1R Variants and Similarities to Those of INSR Variants

607-P: Glycemic Metrics in Japanese Flash Glucose Monitoring Users by Diabetes Type and Therapy

1086-P: A Retrospective Nationwide Surveillance on the First-Line Antidiabetic Medication for the Patients with Type 2 Diabetes in Japan

Lack of Brain Insulin Receptor Substrate-1 Causes Growth Retardation, With Decreased Expression of Growth Hormone–Releasing Hormone in the Hypothalamus

926-P: Cardiovascular (CV) and Hypoglycemia Outcomes across Age Groups in People with Type 2 Diabetes (T2D) in the CAROLINA Trial

887-P: Development of the Noninvasive Diabetes Monitoring Method

1876-P: Gut Microbial Fermentation of Polysaccharides Impacts Insulin Resistance in Humans

1697-P: NFIA Differentially Regulates Adipogenesis and Myogenesis through Distinct Molecular Pathways to Ensure Adipocyte Differentiation

1741-P: Immune Regulation of Postprandial Glycemia and Whole-Body Insulin Sensitivity through Myeloid Production of IL-10

55-OR: Oral Semaglutide vs. Liraglutide and Placebo in T2D: PIONEER 4

1325-P: Effectiveness of Comprehensive Gene Panel-Based Next-Generation Sequencing with Phenotype-Driven Bioinformatics Analysis for Diagnosis of Atypical Diabetes

206-LB: Cardiorenal Disease Is the Most Common First CV Manifestation in Type 2 Diabetes and Associated with Increased Mortality: A Large Multinational Observational Study

Efficacy and Safety of Faster Aspart Compared with Insulin Aspart Both with Insulin Degludec in Adults with T1D

Study of the Correlation between Tear Glucose Concentrations and Blood Glucose Concentrations

Impairment of M2a-Subtype Macrophage Activation by Il-4-Irs2 Pathway in Obesity

Macrophages React to Postprandial Signals and Regulate the Response to Feeding through Akt-mTOR–Dependent Production of IL-10

Tofogliflozin Suppresses the Progression of Atherosclerosis and Reduces Inflammation in Macrophages of STZ-Diabetic ApoE KO Mice due to Improvement of Glucose Tolerance

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