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Meeting Abstracts

1665-P: Novel Spatiotemporal Analysis for Exploring Intestinal L-Cell Genesis and Differentiation

REI FUJISHIMA, TOMOMI TAGUCHI, AGENA SUZUKI, NAOYA SHIMIZU, KAORI KIMURA, SHIORI ITO, TSUGUTO MASAKI, TAKESHI MIYATSUKA

Diabetes 2025;74(Supplement_1):1665-P

https://doi.org/10.2337/db25-1665-P

Published: 20 June 2025

View articletitled, 1665-P: Novel Spatiotemporal Analysis for Exploring Intestinal L-Cell Genesis and Differentiation

Meeting Abstracts

412-P: Nutritional Risk as a Predictor of Hypoglycemia in People with Type 2 Diabetes Undergoing Hemodialysis

AKINORI HAYASHI, HARUNA SOGABE, RIHITO TAKAESU, SATOSHI TSUJI, TATSUMI MORIYA, TAKESHI MIYATSUKA

Diabetes 2025;74(Supplement_1):412-P

https://doi.org/10.2337/db25-412-P

Published: 20 June 2025

View articletitled, 412-P: Nutritional Risk as a Predictor of Hypoglycemia in People with Type 2 Diabetes Undergoing Hemodialysis

Meeting Abstracts

411-P: Renal Arteriolar Hyalinosis Predicts Progressive Renal Functional Decline in Persons with Type 2 Diabetes Showing Macroalbuminuria prior to Impaired Glomerular Filtration

TATSUMI MORIYA, AKIHIKO SUZUKI, AKINORI HAYASHI, TAKESHI MIYATSUKA

Diabetes 2025;74(Supplement_1):411-P

https://doi.org/10.2337/db25-411-P

Published: 20 June 2025

View articletitled, 411-P: Renal Arteriolar Hyalinosis Predicts Progressive Renal Functional Decline in Persons with Type 2 Diabetes Showing Macroalbuminuria prior to Impaired Glomerular Filtration

Meeting Abstracts

1800-P: Distinct Transcriptomic Dynamics between α-Cell and β-Cell Differentiation Revealed by Single-Cell RNA Sequencing

NAOYA SHIMIZU, TOMOMI TAGUCHI, MIWA HIMURO, AGENA SUZUKI, REI FUJISHIMA, IICHIRO SHIMOMURA, HIROTAKA WATADA, FRANCIS C. LYNN, SHUGO SASAKI, TAKESHI MIYATSUKA

Diabetes 2025;74(Supplement_1):1800-P

https://doi.org/10.2337/db25-1800-P

Published: 20 June 2025

View articletitled, 1800-P: Distinct Transcriptomic Dynamics between α-Cell and β-Cell Differentiation Revealed by Single-Cell RNA Sequencing

Meeting Abstracts

629-P: Serum Creatinine–to–Cystatin C Ratio Is Related to Handgrip Strength as Well as Muscle and Fat Mass in People with Type 2 Diabetes Independently of Glycemic Control and Daily Protein Intake

TATSUMI MORIYA, AKIHIKO SUZUKI, MAMIKO HITOMI, MADOKA MATSUBARA, TAKESHI MIYATSUKA

Diabetes 2024;73(Supplement_1):629-P

https://doi.org/10.2337/db24-629-P

Published: 14 June 2024

View articletitled, 629-P: Serum Creatinine–to–Cystatin C Ratio Is Related to Handgrip Strength as Well as Muscle and Fat Mass in People with Type 2 Diabetes Independently of Glycemic Control and Daily Protein Intake

Meeting Abstracts

424-P: Persons with Type 2 Diabetes Who Had Macroalbuminuria Prior to Impaired Glomerular Filtration Exhibited Increased Arteriolar Hyalinosis

AKIHIKO SUZUKI, TATSUMI MORIYA, MADOKA MATSUBARA, AKINORI HAYASHI, TAKESHI MIYATSUKA

Diabetes 2024;73(Supplement_1):424-P

https://doi.org/10.2337/db24-424-P

Published: 14 June 2024

View articletitled, 424-P: Persons with Type 2 Diabetes Who Had Macroalbuminuria Prior to Impaired Glomerular Filtration Exhibited Increased Arteriolar Hyalinosis

Meeting Abstracts

425-P: Retrospective Analysis of Glycemic Profiles and Variabilities Using Continuous Glucose Monitoring in Elderly People with Type 2 Diabetes Undergoing Hemodialysis

AKINORI HAYASHI, KENTA MATOBA, AKIHIKO SUZUKI, TAKESHI MIYATSUKA

Diabetes 2024;73(Supplement_1):425-P

https://doi.org/10.2337/db24-425-P

Published: 14 June 2024

View articletitled, 425-P: Retrospective Analysis of Glycemic Profiles and Variabilities Using Continuous Glucose Monitoring in Elderly People with Type 2 Diabetes Undergoing Hemodialysis

Meeting Abstracts

1722-P: Suppression of Glucagon Signaling Promotes α-to-ß Reprogramming

TOMOMI TAGUCHI, AGENA SUZUKI, NAOYA SHIMIZU, REI FUJISHIMA, KAORI KIMURA, SHIORI ITO, HIDEAKI SHIMOTATARA, MITSUKO INOUE, TAKESHI MIYATSUKA

Diabetes 2024;73(Supplement_1):1722-P

https://doi.org/10.2337/db24-1722-P

Published: 14 June 2024

View articletitled, 1722-P: Suppression of Glucagon Signaling Promotes α-to-ß Reprogramming

Meeting Abstracts

350-OR: Parturition Event Regulates Endocrine Genesis during Pancreas Differentiation

AGENA SUZUKI, TOMOMI TAGUCHI, SHIORI ITO, HIDEAKI SHIMOTATARA, KAORI KIMURA, NAOYA SHIMIZU, REI FUJISHIMA, MIWA HIMURO, TAKESHI MIYATSUKA

Diabetes 2024;73(Supplement_1):350-OR

https://doi.org/10.2337/db24-350-OR

Published: 14 June 2024

View articletitled, 350-OR: Parturition Event Regulates Endocrine Genesis during Pancreas Differentiation

Meeting Abstracts

548-P: Multidisciplinary Team Education Has an Effect on Prevention of Renal Function Decline in Subjects with Diabetes and Macroalbuminuria

MAMIKO HITOMI, TATSUMI MORIYA, TAKESHI MIYATSUKA, NAOKI HIKI

Diabetes 2024;73(Supplement_1):548-P

https://doi.org/10.2337/db24-548-P

Published: 14 June 2024

View articletitled, 548-P: Multidisciplinary Team Education Has an Effect on Prevention of Renal Function Decline in Subjects with Diabetes and Macroalbuminuria

Journal Articles

Establishment of Pancreatic β-Cell–Specific Gene Knockout System Based on CRISPR-Cas9 Technology With AAV8-Mediated gRNA Delivery

Kyosei Ueki, Yuya Nishida, Shuhei Aoyama, Hirotsugu Uzawa, Akiko Kanai, Minami Ito, Koki Ikeda, Hitoshi Iida, Takeshi Miyatsuka, Hirotaka Watada

Diabetes 2023;72(11):1609–1620

https://doi.org/10.2337/db23-0445

Published: 25 August 2023

View articletitled, Establishment of Pancreatic β-Cell–Specific Gene Knockout System Based on CRISPR-Cas9 Technology With AAV8-Mediated gRNA Delivery

Meeting Abstracts

1730-P: Stochastic Differentiation of α-Cell Lineage Revealed by Single-Cell RNA Sequencing in Time-Resolved Reporter System

NAOYA SHIMIZU, SHUGO SASAKI, TOMOMI TAGUCHI, MIWA HIMURO, HIROTAKA WATADA, FRANCIS C. LYNN, TAKESHI MIYATSUKA

Diabetes 2023;72(Supplement_1):1730-P

https://doi.org/10.2337/db23-1730-P

Published: 20 June 2023

View articletitled, 1730-P: Stochastic Differentiation of α-Cell Lineage Revealed by Single-Cell RNA Sequencing in Time-Resolved Reporter System

Meeting Abstracts

429-P: Evaluation of Hypoglycemic Risk in Patients with Type 2 Diabetes on Hemodialysis under Tight Glycemic Control

AKINORI HAYASHI, NAOYA SHIMIZU, AGENA SUZUKI, REI FUJISHIMA, KENTA MATOBA, TSUGUTO MASAKI, TAKESHI MIYATSUKA

Diabetes 2023;72(Supplement_1):429-P

https://doi.org/10.2337/db23-429-P

Published: 20 June 2023

View articletitled, 429-P: Evaluation of Hypoglycemic Risk in Patients with Type 2 Diabetes on Hemodialysis under Tight Glycemic Control

Meeting Abstracts

428-P: Diabetic Retinopathy Predicts Hemodialysis Induction in Subjects with Type 2 Diabetes with Normo- and Microalbuminuria and Normal Renal Function

TATSUMI MORIYA, AKIHIKO SUZUKI, AKINORI HAYASHI, MADOKA MATSUBARA, TAKESHI MIYATSUKA

Diabetes 2023;72(Supplement_1):428-P

https://doi.org/10.2337/db23-428-P

Published: 20 June 2023

View articletitled, 428-P: Diabetic Retinopathy Predicts Hemodialysis Induction in Subjects with Type 2 Diabetes with Normo- and Microalbuminuria and Normal Renal Function

Meeting Abstracts

531-P: The Multidisciplinary Team Education for Subjects with DKD Could Affect the Prevention of eGFR Decline

MAMIKO HITOMI, NAOKI HIKI, UMEKO SAKAMOTO, YUURI USUI, TAKESHI MIYATSUKA, TATSUMI MORIYA

Diabetes 2023;72(Supplement_1):531-P

https://doi.org/10.2337/db23-531-P

Published: 20 June 2023

View articletitled, 531-P: The Multidisciplinary Team Education for Subjects with DKD Could Affect the Prevention of eGFR Decline

Meeting Abstracts

225-OR: The Impact of Visualizing Macronutrient Content via Food-Log App "Calomeal" on Glycemic Control and QoL in People with Type 2 Diabetes

ASAKO TSUNEMI, JUNKO SATO, MARI ENOMOTO, YUKO IWAGAKI, SAKAE SUGIMOTO, YUKI SOMEYA, MAI KIYA, EIKO MATSUHASHI, YUKA WAKABAYASHI, TAKASHI FUNAYAMA, TOYOYOSHI UCHIDA, TAKESHI MIYATSUKA, KOSUKE AZUMA, TOMOAKI SHIMIZU, HIROAKI SATOH, AKIO KANAZAWA, HIROTAKA WATADA

Diabetes 2020;69(Supplement_1):225-OR

https://doi.org/10.2337/db20-225-OR

Published: 01 June 2020

View articletitled, 225-OR: The Impact of Visualizing Macronutrient Content via Food-Log App "Calomeal" on Glycemic Control and QoL in People with Type 2 Diabetes

Meeting Abstracts

2128-P: Exploring the Role of Autophagy in Pancreatic Alpha Cells

MIWA HIMURO, TAKESHI MIYATSUKA, LUKA SUZUKI, MASAKI MIURA, TAKEHIRO KATAHIRA, HIROMASA GOTO, YUYA NISHIDA, SHUGO SASAKI, YOSHIO FUJITANI, HIROTAKA WATADA

Diabetes 2019;68(Supplement_1):2128-P

https://doi.org/10.2337/db19-2128-P

Published: 01 June 2019

View articletitled, 2128-P: Exploring the Role of Autophagy in Pancreatic Alpha Cells

Meeting Abstracts

2162-P: Autophagy Deficiency Cumulatively Causes ß-Cell Failure in Mice

LUKA SUZUKI, TAKESHI MIYATSUKA, MIWA HIMURO, MASAKI MIURA, TAKEHIRO KATAHIRA, KOJI KOMIYA, YOSHIO FUJITANI, YUYA NISHIDA, HIROTAKA WATADA

Diabetes 2019;68(Supplement_1):2162-P

https://doi.org/10.2337/db19-2162-P

Published: 01 June 2019

View articletitled, 2162-P: Autophagy Deficiency Cumulatively Causes ß-Cell Failure in Mice

Meeting Abstracts

2185-P: Estimation of Autophagy Flux by a Novel Fluorescent Reporter in Organs Involved in Glucose Metabolism Including Pancreatic ß Cells

SHUHEI AOYAMA, YUYA NISHIDA, RIEKO YAZAWA, ISEI TANIDA, TAKESHI MIYATSUKA, HIROTAKA WATADA

Diabetes 2019;68(Supplement_1):2185-P

https://doi.org/10.2337/db19-2185-P

Published: 01 June 2019

View articletitled, 2185-P: Estimation of Autophagy Flux by a Novel Fluorescent Reporter in Organs Involved in Glucose Metabolism Including Pancreatic ß Cells

Meeting Abstracts

346-LB: The Role of STAT3 Signaling toward a-to-ß Reprogramming within the Adult Pancreas

YUKA WAKABAYASHI, TAKESHI MIYATSUKA, LUKA SUZUKI, MIWA HIMURO, TAKEHIRO KATAHIRA, MASAKI MIURA, HIROTAKA WATADA

Diabetes 2019;68(Supplement_1):346-LB

https://doi.org/10.2337/db19-346-LB

Published: 01 June 2019

View articletitled, 346-LB: The Role of STAT3 Signaling toward a-to-ß Reprogramming within the Adult Pancreas

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1665-P: Novel Spatiotemporal Analysis for Exploring Intestinal L-Cell Genesis and Differentiation

412-P: Nutritional Risk as a Predictor of Hypoglycemia in People with Type 2 Diabetes Undergoing Hemodialysis

411-P: Renal Arteriolar Hyalinosis Predicts Progressive Renal Functional Decline in Persons with Type 2 Diabetes Showing Macroalbuminuria prior to Impaired Glomerular Filtration

1800-P: Distinct Transcriptomic Dynamics between α-Cell and β-Cell Differentiation Revealed by Single-Cell RNA Sequencing

629-P: Serum Creatinine–to–Cystatin C Ratio Is Related to Handgrip Strength as Well as Muscle and Fat Mass in People with Type 2 Diabetes Independently of Glycemic Control and Daily Protein Intake

424-P: Persons with Type 2 Diabetes Who Had Macroalbuminuria Prior to Impaired Glomerular Filtration Exhibited Increased Arteriolar Hyalinosis

425-P: Retrospective Analysis of Glycemic Profiles and Variabilities Using Continuous Glucose Monitoring in Elderly People with Type 2 Diabetes Undergoing Hemodialysis

1722-P: Suppression of Glucagon Signaling Promotes α-to-ß Reprogramming

350-OR: Parturition Event Regulates Endocrine Genesis during Pancreas Differentiation

548-P: Multidisciplinary Team Education Has an Effect on Prevention of Renal Function Decline in Subjects with Diabetes and Macroalbuminuria

Establishment of Pancreatic β-Cell–Specific Gene Knockout System Based on CRISPR-Cas9 Technology With AAV8-Mediated gRNA Delivery

1730-P: Stochastic Differentiation of α-Cell Lineage Revealed by Single-Cell RNA Sequencing in Time-Resolved Reporter System

429-P: Evaluation of Hypoglycemic Risk in Patients with Type 2 Diabetes on Hemodialysis under Tight Glycemic Control

428-P: Diabetic Retinopathy Predicts Hemodialysis Induction in Subjects with Type 2 Diabetes with Normo- and Microalbuminuria and Normal Renal Function

531-P: The Multidisciplinary Team Education for Subjects with DKD Could Affect the Prevention of eGFR Decline

225-OR: The Impact of Visualizing Macronutrient Content via Food-Log App "Calomeal" on Glycemic Control and QoL in People with Type 2 Diabetes

2128-P: Exploring the Role of Autophagy in Pancreatic Alpha Cells

2162-P: Autophagy Deficiency Cumulatively Causes ß-Cell Failure in Mice

2185-P: Estimation of Autophagy Flux by a Novel Fluorescent Reporter in Organs Involved in Glucose Metabolism Including Pancreatic ß Cells

346-LB: The Role of STAT3 Signaling toward a-to-ß Reprogramming within the Adult Pancreas

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