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Timothy I.M. Tree
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Journal Articles

Natural Variation in Interleukin-2 Sensitivity Influences Regulatory T-Cell Frequency and Function in Individuals With Long-standing Type 1 Diabetes

Free
Jennie H.M. Yang, Antony J. Cutler, Ricardo C. Ferreira, James L. Reading, Nicholas J. Cooper, Chris Wallace, Pamela Clarke, Deborah J. Smyth, Christopher S. Boyce, Guo-Jian Gao, John A. Todd, Linda S. Wicker, Timothy I.M. Tree
Journal: Diabetes
Diabetes 2015;64(11):3891–3902
https://doi.org/10.2337/db15-0516
Published: 29 July 2015
View articletitled, Natural Variation in Interleukin-2 Sensitivity Influences Regulatory T-Cell Frequency and Function in Individuals With Long-standing Type 1 Diabetes
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Includes: Supplementary data
Journal Articles

Naturally Arising Human CD4 T-Cells That Recognize Islet Autoantigens and Secrete Interleukin-10 Regulate Proinflammatory T-Cell Responses via Linked Suppression

Open Access
Timothy I.M. Tree, Jennifer Lawson, Hannah Edwards, Ania Skowera, Sefina Arif, Bart O. Roep, Mark Peakman
Journal: Diabetes
Diabetes 2010;59(6):1451–1460
https://doi.org/10.2337/db09-0503
Published: 18 March 2010
View articletitled, Naturally Arising Human CD4 T-Cells That Recognize Islet Autoantigens and Secrete Interleukin-10 Regulate Proinflammatory T-Cell Responses via Linked Suppression
Open the PDF for Naturally Arising Human CD4 T-Cells That Recognize Islet Autoantigens and Secrete Interleukin-10 Regulate Proinflammatory T-Cell Responses via Linked Suppression in another window
Includes: Supplementary data
Journal Articles

Defective Suppressor Function in CD4+CD25+ T-Cells From Patients With Type 1 Diabetes

Free
Shelley Lindley, Colin M. Dayan, Amanda Bishop, Bart O. Roep, Mark Peakman, Timothy I.M. Tree
Journal: Diabetes
Diabetes 2005;54(1):92–99
https://doi.org/10.2337/diabetes.54.1.92
Published: 01 January 2005
View articletitled, Defective Suppressor Function in CD4+CD25+ T-Cells From Patients With Type 1 Diabetes
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Journal Articles

HLA-DQ–Regulated T-Cell Responses to Islet Cell Autoantigens Insulin and GAD65

Free
Timothy I.M. Tree, Gaby Duinkerken, Sabine Willemen, René R.P. de Vries, Bart O. Roep
Journal: Diabetes
Diabetes 2004;53(7):1692–1699
https://doi.org/10.2337/diabetes.53.7.1692
Published: 01 July 2004
View articletitled, HLA-DQ–Regulated T-Cell Responses to Islet Cell Autoantigens Insulin and GAD65
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Journal Articles

Processing and Presentation of the Islet Autoantigen GAD by Vascular Endothelial Cells Promotes Transmigration of Autoreactive T-Cells

Free
James E. Greening, Timothy I.M. Tree, Karolena T. Kotowicz, Astrid G. van Halteren, Bart O. Roep, Nigel J. Klein, Mark Peakman
Journal: Diabetes
Diabetes 2003;52(3):717–725
https://doi.org/10.2337/diabetes.52.3.717
Published: 01 March 2003
View articletitled, Processing and Presentation of the Islet Autoantigen GAD by Vascular Endothelial Cells Promotes Transmigration of Autoreactive T-Cells
Open the PDF for Processing and Presentation of the Islet Autoantigen GAD by Vascular Endothelial Cells Promotes Transmigration of Autoreactive T-Cells in another window