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Timothy J. Pullen
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Journal Articles

Distinct Molecular Signatures of Clinical Clusters in People With Type 2 Diabetes: An IMI-RHAPSODY Study

Free
Roderick C. Slieker, Louise A. Donnelly, Hugo Fitipaldi, Gerard A. Bouland, Giuseppe N. Giordano, Mikael Åkerlund, Mathias J. Gerl, Emma Ahlqvist, Ashfaq Ali, Iulian Dragan, Petra Elders, Andreas Festa, Michael K. Hansen, Amber A. van der Heijden, Dina Mansour Aly, Min Kim, Dmitry Kuznetsov, Florence Mehl, Christian Klose, Kai Simons, Imre Pavo, Timothy J. Pullen, Tommi Suvitaival, Asger Wretlind, Peter Rossing, Valeriya Lyssenko, Cristina Legido Quigley, Leif Groop, Bernard Thorens, Paul W. Franks, Mark Ibberson, Guy A. Rutter, Joline W.J. Beulens, Leen M. ’t Hart, Ewan R. Pearson
Journal: Diabetes
Diabetes 2021;70(11):2683–2693
https://doi.org/10.2337/db20-1281
Published: 10 August 2021
View article titled, Distinct Molecular Signatures of Clinical Clusters in People With Type 2 Diabetes: An IMI-RHAPSODY Study
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Meeting Abstracts

343-LB: The Type 2 Diabetes-Associated Lipid Binding Protein STARD10 Controls Insulin Secretory Granule Biogenesis

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GAELLE CARRAT, ELIZABETH HAYTHORNE, LEENA HAATAJA, PETER ARVAN, ALEJANDRA TOMAS, ALEXANDRA PIUNTI, TIMOTHY J. PULLEN, ELENI GEORGIADOU, THEODOROS STYLIANIDES, VICTORIA SALEM, WALTER DISTASO, ANDREW CAKEBREAD, DAVID HODSON, ANNIE C. FUNG, RICHARD B. SESSIONS, FABIEN ALPY, ALICE P. KONG, ISABELLE LECLERC, GUY A. RUTTER
Journal: Diabetes
Diabetes 2019;68(Supplement_1):343-LB
https://doi.org/10.2337/db19-343-LB
Published: 01 June 2019
View article titled, 343-LB: The Type 2 Diabetes-Associated Lipid Binding Protein STARD10 Controls Insulin Secretory Granule Biogenesis
Journal Articles

Disallowance of Acot7 in β-Cells Is Required for Normal Glucose Tolerance and Insulin Secretion

Free
Aida Martinez-Sanchez, Timothy J. Pullen, Pauline Chabosseau, Qifeng Zhang, Elizabeth Haythorne, Matthew C. Cane, Marie-Sophie Nguyen-Tu, Sophie R. Sayers, Guy A. Rutter
Journal: Diabetes
Diabetes 2016;65(5):1268–1282
https://doi.org/10.2337/db15-1240
Published: 09 February 2016
View article titled, Disallowance of Acot7 in β-Cells Is Required for Normal Glucose Tolerance and Insulin Secretion
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Includes: Supplementary data
Journal Articles

ADCY5 Couples Glucose to Insulin Secretion in Human Islets

Free
David J. Hodson, Ryan K. Mitchell, Lorella Marselli, Timothy J. Pullen, Silvia Gimeno Brias, Francesca Semplici, Katy L. Everett, Dermot M.F. Cooper, Marco Bugliani, Piero Marchetti, Vanessa Lavallard, Domenico Bosco, Lorenzo Piemonti, Paul R. Johnson, Stephen J. Hughes, Daliang Li, Wen-Hong Li, A.M. James Shapiro, Guy A. Rutter
Journal: Diabetes
Diabetes 2014;63(9):3009–3021
https://doi.org/10.2337/db13-1607
Published: 16 August 2014
View article titled, ADCY5 Couples Glucose to Insulin Secretion in Human Islets
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Includes: Supplementary data
Journal Articles

Comment on: Schuit et al. β-Cell–Specific Gene Repression: A Mechanism to Protect Against Inappropriate or Maladjusted Insulin Secretion? Diabetes 2012;61:969–975

Open Access
Guy A. Rutter, Timothy J. Pullen
Journal: Diabetes
Diabetes 2012;61(10):e16
https://doi.org/10.2337/db12-0775
Published: 13 September 2012
View article titled, Comment on: Schuit et al. β-Cell–Specific Gene Repression: A Mechanism to Protect Against Inappropriate or Maladjusted Insulin Secretion? Diabetes 2012;61:969–975
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Journal Articles

Overexpression of Monocarboxylate Transporter-1 (Slc16a1) in Mouse Pancreatic β-Cells Leads to Relative Hyperinsulinism During Exercise

Open Access
Timothy J. Pullen, Lykke Sylow, Gao Sun, Andrew P. Halestrap, Erik A. Richter, Guy A. Rutter
Journal: Diabetes
Diabetes 2012;61(7):1719–1725
https://doi.org/10.2337/db11-1531
Published: 15 June 2012
View article titled, Overexpression of Monocarboxylate Transporter-1 (Slc16a1) in Mouse Pancreatic β-Cells Leads to Relative Hyperinsulinism During Exercise
Open the PDF for Overexpression of Monocarboxylate Transporter-1 (Slc16a1) in Mouse Pancreatic β-Cells Leads to Relative Hyperinsulinism During Exercise in another window
Includes: Supplementary data
Journal Articles

Carbohydrate-Responsive Element-Binding Protein (ChREBP) Is a Negative Regulator of ARNT/HIF-1β Gene Expression in Pancreatic Islet β-Cells

Open Access
Nafeesa A. Noordeen, Tarnjit K. Khera, Gao Sun, E. Rebecca Longbottom, Timothy J. Pullen, Gabriela da Silva Xavier, Guy A. Rutter, Isabelle Leclerc
Journal: Diabetes
Diabetes 2010;59(1):153–160
https://doi.org/10.2337/db08-0868
Published: 15 October 2009
View article titled, Carbohydrate-Responsive Element-Binding Protein (ChREBP) Is a Negative Regulator of ARNT/HIF-1β Gene Expression in Pancreatic Islet β-Cells
Open the PDF for Carbohydrate-Responsive Element-Binding Protein (ChREBP) Is a Negative Regulator of ARNT/HIF-1β Gene Expression in Pancreatic Islet β-Cells in another window
Includes: Supplementary data