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Journal Articles

Immune and Metabolic Effects of Antigen-Specific Immunotherapy Using Multiple β-Cell Peptides in Type 1 Diabetes

Free
Yuk-Fun Liu, Jake Powrie, Sefina Arif, Jennie H.M. Yang, Evangelia Williams, Leena Khatri, Mamta Joshi, Loic Lhuillier, Nikolaos Fountoulakis, Emma Smith, Craig Beam, Anna Lorenc, Mark Peakman, Timothy Tree
Journal: Diabetes
Diabetes 2022;71(4):722–732
https://doi.org/10.2337/db21-0728
Published: 24 January 2022
View articletitled, Immune and Metabolic Effects of Antigen-Specific Immunotherapy Using Multiple β-Cell Peptides in Type 1 Diabetes
Open the PDF for Immune and Metabolic Effects of Antigen-Specific Immunotherapy Using Multiple β-Cell Peptides in Type 1 Diabetes in another window
Journal Articles

Standardizing T-Cell Biomarkers in Type 1 Diabetes: Challenges and Recent Advances

Free
Simi Ahmed, Karen Cerosaletti, Eddie James, S. Alice Long, Stuart Mannering, Cate Speake, Maki Nakayama, Timothy Tree, Bart O. Roep, Kevan C. Herold, Todd M. Brusko
Journal: Diabetes
Diabetes 2019;68(7):1366–1379
https://doi.org/10.2337/db19-0119
Published: 13 June 2019
View articletitled, Standardizing T-Cell Biomarkers in Type 1 Diabetes: Challenges and Recent Advances
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Includes: Supplementary data
Journal Articles

Peripheral and Islet Interleukin-17 Pathway Activation Characterizes Human Autoimmune Diabetes and Promotes Cytokine-Mediated β-Cell Death

Open Access
Sefina Arif, Fabrice Moore, Katherine Marks, Thomas Bouckenooghe, Colin M. Dayan, Raquel Planas, Marta Vives-Pi, Jake Powrie, Timothy Tree, Piero Marchetti, Guo Cai Huang, Esteban N. Gurzov, Ricardo Pujol-Borrell, Decio L. Eizirik, Mark Peakman
Journal: Diabetes
Diabetes 2011;60(8):2112–2119
https://doi.org/10.2337/db10-1643
Published: 18 July 2011
View articletitled, Peripheral and Islet Interleukin-17 Pathway Activation Characterizes Human Autoimmune Diabetes and Promotes Cytokine-Mediated β-Cell Death
Open the PDF for Peripheral and Islet Interleukin-17 Pathway Activation Characterizes Human Autoimmune Diabetes and Promotes Cytokine-Mediated β-Cell Death in another window
Includes: Supplementary data
Journal Articles

Plasmacytoid Dendritic Cells Are Proportionally Expanded at Diagnosis of Type 1 Diabetes and Enhance Islet Autoantigen Presentation to T-Cells Through Immune Complex Capture

Free
Jennifer S. Allen, Karl Pang, Ania Skowera, Richard Ellis, Chloe Rackham, Biliana Lozanoska-Ochser, Timothy Tree, R. David G. Leslie, Jennifer M. Tremble, Colin M. Dayan, Mark Peakman
Journal: Diabetes
Diabetes 2009;58(1):138–145
https://doi.org/10.2337/db08-0964
Published: 01 January 2009
View articletitled, Plasmacytoid Dendritic Cells Are Proportionally Expanded at Diagnosis of Type 1 Diabetes and Enhance Islet Autoantigen Presentation to T-Cells Through Immune Complex Capture
Open the PDF for Plasmacytoid Dendritic Cells Are Proportionally Expanded at Diagnosis of Type 1 Diabetes and Enhance Islet Autoantigen Presentation to T-Cells Through Immune Complex Capture in another window
Includes: Supplementary data