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Toshimasa Yamauchi
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Meeting Abstracts

1016-P: Development of Highly Accurate Measurement Method of Salivary Glycated Albumin by HPLC

MASAKAZU AIHARA, NAOTO KUBOTA, TOSHIMASA YAMAUCHI
Journal: Diabetes
Diabetes 2024;73(Supplement_1):1016-P
https://doi.org/10.2337/db24-1016-P
Published: 14 June 2024
View articletitled, 1016-P: Development of Highly Accurate Measurement Method of Salivary Glycated Albumin by HPLC
Journal Articles

Overexpression of UBE2E2 in Mouse Pancreatic β-Cells Leads to Glucose Intolerance via Reduction of β-Cell Mass

Yoshitaka Sakurai, Naoto Kubota, Iseki Takamoto, Nobuhiro Wada, Masakazu Aihara, Takanori Hayashi, Tetsuya Kubota, Yuta Hiraike, Takayoshi Sasako, Harumi Nakao, Atsu Aiba, Yoko Chikaoka, Takeshi Kawamura, Takashi Kadowaki, Toshimasa Yamauchi
Journal: Diabetes
Diabetes 2024;73(3):474–489
https://doi.org/10.2337/db23-0150
Published: 08 December 2023
View articletitled, Overexpression of UBE2E2 in Mouse Pancreatic β-Cells Leads to Glucose Intolerance via Reduction of β-Cell Mass
Open the PDF for Overexpression of UBE2E2 in Mouse Pancreatic β-Cells Leads to Glucose Intolerance via Reduction of β-Cell Mass in another window
Meeting Abstracts

631-P: Development of Noninvasive Diabetes Management Method Using Glycated Albumin in Tears

MASAKAZU AIHARA, NAOTO KUBOTA, TOSHIMASA YAMAUCHI
Journal: Diabetes
Diabetes 2023;72(Supplement_1):631-P
https://doi.org/10.2337/db23-631-P
Published: 20 June 2023
View articletitled, 631-P: Development of Noninvasive Diabetes Management Method Using Glycated Albumin in Tears
Meeting Abstracts

1086-P: A Retrospective Nationwide Surveillance on the First-Line Antidiabetic Medication for the Patients with Type 2 Diabetes in Japan

RYOTARO BOUCHI, TAKEHIRO SUGIYAMA, ATSUSHI GOTO, KENJIRO IMAI, NORIKO IHANA-SUGIYAMA, MITSURU OHSUGI, TOSHIMASA YAMAUCHI, TAKASHI KADOWAKI, KOHJIRO UEKI
Journal: Diabetes
Diabetes 2021;70(Supplement_1):1086-P
https://doi.org/10.2337/db21-1086-P
Published: 01 June 2021
View articletitled, 1086-P: A Retrospective Nationwide Surveillance on the First-Line Antidiabetic Medication for the Patients with Type 2 Diabetes in Japan
Journal Articles

Genotype-Structure-Phenotype Correlations of Disease-Associated IGF1R Variants and Similarities to Those of INSR Variants

Jun Hosoe, Yuki Kawashima-Sonoyama, Fuyuki Miya, Hiroko Kadowaki, Ken Suzuki, Takashi Kato, Fumiko Matsuzawa, Sei-Ichi Aikawa, Yukinori Okada, Tatsuhiko Tsunoda, Keiichi Hanaki, Susumu Kanzaki, Nobuhiro Shojima, Toshimasa Yamauchi, Takashi Kadowaki
Journal: Diabetes
Diabetes 2021;70(8):1874–1884
https://doi.org/10.2337/db20-1145
Published: 01 June 2021
View articletitled, Genotype-Structure-Phenotype Correlations of Disease-Associated IGF1R Variants and Similarities to Those of INSR Variants
Open the PDF for Genotype-Structure-Phenotype Correlations of Disease-Associated IGF1R Variants and Similarities to Those of INSR Variants in another window
Journal Articles

Lack of Brain Insulin Receptor Substrate-1 Causes Growth Retardation, With Decreased Expression of Growth Hormone–Releasing Hormone in the Hypothalamus

Takanori Hayashi, Tetsuya Kubota, Inoue Mariko, Iseki Takamoto, Masakazu Aihara, Yoshitaka Sakurai, Nobuhiro Wada, Takashi Miki, Toshimasa Yamauchi, Naoto Kubota, Takashi Kadowaki
Journal: Diabetes
Diabetes 2021;70(8):1640–1653
https://doi.org/10.2337/db20-0482
Published: 12 May 2021
View articletitled, Lack of Brain Insulin Receptor Substrate-1 Causes Growth Retardation, With Decreased Expression of Growth Hormone–Releasing Hormone in the Hypothalamus
Open the PDF for Lack of Brain Insulin Receptor Substrate-1 Causes Growth Retardation, With Decreased Expression of Growth Hormone–Releasing Hormone in the Hypothalamus in another window
Meeting Abstracts

1697-P: NFIA Differentially Regulates Adipogenesis and Myogenesis through Distinct Molecular Pathways to Ensure Adipocyte Differentiation

YUTA HIRAIKE, HIRONORI WAKI, KANA MIYAKE, MISATO OGUCHI, TOSHIMASA YAMAUCHI, TAKASHI KADOWAKI
Journal: Diabetes
Diabetes 2020;69(Supplement_1):1697-P
https://doi.org/10.2337/db20-1697-P
Published: 01 June 2020
View articletitled, 1697-P: NFIA Differentially Regulates Adipogenesis and Myogenesis through Distinct Molecular Pathways to Ensure Adipocyte Differentiation
Meeting Abstracts

1741-P: Immune Regulation of Postprandial Glycemia and Whole-Body Insulin Sensitivity through Myeloid Production of IL-10

GOTARO TODA, KOTARO SOEDA, NAOKO ARAKAWA, YUKARI MASUDA, NAOKI KOBAYASHI, HIROTSUGU SUWANAI, YOSHIHIKO IZUMIDA, TOSHIMASA YAMAUCHI, TAKASHI KADOWAKI, KOHJIRO UEKI
Journal: Diabetes
Diabetes 2020;69(Supplement_1):1741-P
https://doi.org/10.2337/db20-1741-P
Published: 01 June 2020
View articletitled, 1741-P: Immune Regulation of Postprandial Glycemia and Whole-Body Insulin Sensitivity through Myeloid Production of IL-10
Meeting Abstracts

1325-P: Effectiveness of Comprehensive Gene Panel-Based Next-Generation Sequencing with Phenotype-Driven Bioinformatics Analysis for Diagnosis of Atypical Diabetes

JUN HOSOE, HIROKO KADOWAKI, FUYUKI MIYA, MINAKA TAKAKURA, HIRONORI WAKI, TAKAYOSHI SASAKO, TAKASHI KATO, TATSUHIKO TSUNODA, NOBUHIRO SHOJIMA, TOSHIMASA YAMAUCHI, TAKASHI KADOWAKI
Journal: Diabetes
Diabetes 2019;68(Supplement_1):1325-P
https://doi.org/10.2337/db19-1325-P
Published: 01 June 2019
View articletitled, 1325-P: Effectiveness of Comprehensive Gene Panel-Based Next-Generation Sequencing with Phenotype-Driven Bioinformatics Analysis for Diagnosis of Atypical Diabetes
Meeting Abstracts

Genotype–Phenotype Correlations and Structural Basis of INSR and IGF1R Mutations Causing Severe Insulin/IGF-1 Resistance

JUN HOSOE, HIROKO KADOWAKI, FUYUKI MIYA, MINAKA TAKAKURA, TATSUHIKO TSUNODA, NOBUHIRO SHOJIMA, TOSHIMASA YAMAUCHI, TAKASHI KADOWAKI
Journal: Diabetes
Diabetes 2018;67(Supplement_1):1349-P
https://doi.org/10.2337/db18-1349-P
Published: 01 July 2018
View articletitled, Genotype–Phenotype Correlations and Structural Basis of INSR and IGF1R Mutations Causing Severe Insulin/IGF-1 Resistance
Meeting Abstracts

Sodium-Glucose Cotransporter 2 Inhibitors for Type 1 Diabetes Mellitus—Systematic Review and Meta-analysis

TOMOHIDE YAMADA, JUN HOSOE, NOBUHIRO SHOJIMA, TOSHIMASA YAMAUCHI, TAKASHI KADOWAKI
Journal: Diabetes
Diabetes 2018;67(Supplement_1):1128-P
https://doi.org/10.2337/db18-1128-P
Published: 01 July 2018
View articletitled, Sodium-Glucose Cotransporter 2 Inhibitors for Type 1 Diabetes Mellitus—Systematic Review and Meta-analysis
Meeting Abstracts

Human Brown Adipose Tissue Density Assessed by Near-Infrared Time-Resolved Spectroscopy Inversely Correlates with the Body Mass Index in Patients with Type 2 Diabetes

HIRONORI WAKI, NAOKO WATANABE, SAYURI FUSE, YUKO KUROSAWA, TOSHIMASA YAMAUCHI, RYOTARO KIME, TAKAFUMI HAMAOKA, TAKASHI KADOWAKI
Journal: Diabetes
Diabetes 2018;67(Supplement_1):2080-P
https://doi.org/10.2337/db18-2080-P
Published: 01 July 2018
View articletitled, Human Brown Adipose Tissue Density Assessed by Near-Infrared Time-Resolved Spectroscopy Inversely Correlates with the Body Mass Index in Patients with Type 2 Diabetes
Meeting Abstracts

NFIA Colocalizes with PPARgamma and Activates the Cell-Type–Specific Enhancers to Control the Brown Fat Gene Program

YUTA HIRAIKE, HIRONORI WAKI, SHUICHI TSUTSUMI, HIROYUKI ABURATANI, TOSHIMASA YAMAUCHI, TAKASHI KADOWAKI
Journal: Diabetes
Diabetes 2018;67(Supplement_1):270-OR
https://doi.org/10.2337/db18-270-OR
Published: 01 July 2018
View articletitled, NFIA Colocalizes with PPARgamma and Activates the Cell-Type–Specific Enhancers to Control the Brown Fat Gene Program
Meeting Abstracts

Impairment of M2a-Subtype Macrophage Activation by Il-4-Irs2 Pathway in Obesity

TETSUYA KUBOTA, MARIKO INOUE, NAOTO KUBOTA, ISEKI TAKAMOTO, KOHJIRO UEKI, TOSHIMASA YAMAUCHI, TAKASHI KADOWAKI
Journal: Diabetes
Diabetes 2018;67(Supplement_1):2012-P
https://doi.org/10.2337/db18-2012-P
Published: 01 July 2018
View articletitled, Impairment of M2a-Subtype Macrophage Activation by Il-4-Irs2 Pathway in Obesity
Journal Articles

Structural Basis and Genotype–Phenotype Correlations of INSR Mutations Causing Severe Insulin Resistance

Jun Hosoe, Hiroko Kadowaki, Fuyuki Miya, Katsuya Aizu, Tomoyuki Kawamura, Ichiro Miyata, Kenichi Satomura, Takeru Ito, Kazuo Hara, Masaki Tanaka, Hiroyuki Ishiura, Shoji Tsuji, Ken Suzuki, Minaka Takakura, Keith A. Boroevich, Tatsuhiko Tsunoda, Toshimasa Yamauchi, Nobuhiro Shojima, Takashi Kadowaki
Journal: Diabetes
Diabetes 2017;66(10):2713–2723
https://doi.org/10.2337/db17-0301
Published: 01 August 2017
View articletitled, Structural Basis and Genotype–Phenotype Correlations of INSR Mutations Causing Severe Insulin Resistance
Open the PDF for Structural Basis and Genotype–Phenotype Correlations of INSR Mutations Causing Severe Insulin Resistance in another window
Includes: Supplementary data
Journal Articles

Genome-Wide Association Meta-analysis Identifies Novel Variants Associated With Fasting Plasma Glucose in East Asians

Joo-Yeon Hwang, Xueling Sim, Ying Wu, Jun Liang, Yasuharu Tabara, Cheng Hu, Kazuo Hara, Claudia H.T. Tam, Qiuyin Cai, Qi Zhao, Sunha Jee, Fumihiko Takeuchi, Min Jin Go, Rick Twee Hee Ong, Takayoshi Ohkubo, Young Jin Kim, Rong Zhang, Toshimasa Yamauchi, Wing Yee So, Jirong Long, Dongfeng Gu, Nanette R. Lee, Soriul Kim, Tomohiro Katsuya, Ji Hee Oh, Jianjun Liu, Satoshi Umemura, Yeon-Jung Kim, Feng Jiang, Shiro Maeda, Juliana C.N. Chan, Wei Lu, James E. Hixson, Linda S. Adair, Keum Ji Jung, Toru Nabika, Jae-Bum Bae, Mi Hee Lee, Mark Seielstad, Terri L. Young, Yik Ying Teo, Yoshikuni Kita, Naoyuki Takashima, Haruhiko Osawa, So-Hyun Lee, Min-Ho Shin, Dong Hoon Shin, Bo Youl Choi, Jiajun Shi, Yu-Tang Gao, Yong-Bing Xiang, Wei Zheng, Norihiro Kato, Miwuk Yoon, Jiang He, Xiao Ou Shu, Ronald C.W. Ma, Takashi Kadowaki, Weiping Jia, Tetsuro Miki, Lu Qi, E Shyong Tai, Karen L. Mohlke, Bok-Ghee Han, Yoon Shin Cho, Bong-Jo Kim
Journal: Diabetes
Diabetes 2015;64(1):291–298
https://doi.org/10.2337/db14-0563
Published: 03 September 2014
View articletitled, Genome-Wide Association Meta-analysis Identifies Novel Variants Associated With Fasting Plasma Glucose in East Asians
Open the PDF for Genome-Wide Association Meta-analysis Identifies Novel Variants Associated With Fasting Plasma Glucose in East Asians in another window
Includes: Supplementary data
Journal Articles

Genome-Wide Association Study Identifies a Novel Locus Contributing to Type 2 Diabetes Susceptibility in Sikhs of Punjabi Origin From India

Richa Saxena, Danish Saleheen, Latonya F. Been, Martha L. Garavito, Timothy Braun, Andrew Bjonnes, Robin Young, Weang Kee Ho, Asif Rasheed, Philippe Frossard, Xueling Sim, Neelam Hassanali, Venkatesan Radha, Manickam Chidambaram, Samuel Liju, Simon D. Rees, Daniel Peng-Keat Ng, Tien-Yin Wong, Toshimasa Yamauchi, Kazuo Hara, Yasushi Tanaka, Hiroshi Hirose, Mark I. McCarthy, Andrew P. Morris, DIAGRAM, MuTHER, AGEN, Abdul Basit, Anthony H. Barnett, Prasad Katulanda, David Matthews, Viswanathan Mohan, Gurpreet S. Wander, Jai Rup Singh, Narinder K. Mehra, Sarju Ralhan, M. Ilyas Kamboh, John J. Mulvihill, Hiroshi Maegawa, Kazuyuki Tobe, Shiro Maeda, Yoon S. Cho, E. Shyong Tai, M. Ann Kelly, John C. Chambers, Jaspal S. Kooner, Takashi Kadowaki, Panos Deloukas, Daniel J. Rader, John Danesh, Dharambir K. Sanghera
Journal: Diabetes
Diabetes 2013;62(5):1746–1755
https://doi.org/10.2337/db12-1077
Published: 16 April 2013
View articletitled, Genome-Wide Association Study Identifies a Novel Locus Contributing to Type 2 Diabetes Susceptibility in Sikhs of Punjabi Origin From India
Open the PDF for Genome-Wide Association Study Identifies a Novel Locus Contributing to Type 2 Diabetes Susceptibility in Sikhs of Punjabi Origin From India in another window
Includes: Supplementary data
Journal Articles

Adiponectin-Dependent and -Independent Pathways in Insulin-Sensitizing and Antidiabetic Actions of Thiazolidinediones

Naoto Kubota, Toshimasa Yamauchi, Kazuyuki Tobe, Takashi Kadowaki
Journal: Diabetes
Diabetes 2006;55(Supplement_2):S32–S38
https://doi.org/10.2337/db06-S005
Published: 01 December 2006
View articletitled, Adiponectin-Dependent and -Independent Pathways in Insulin-Sensitizing and Antidiabetic Actions of Thiazolidinediones
Open the PDF for Adiponectin-Dependent and -Independent Pathways in Insulin-Sensitizing and Antidiabetic Actions of Thiazolidinediones in another window
Journal Articles

Peroxisome Proliferator–Activated Receptor (PPAR)α Activation Increases Adiponectin Receptors and Reduces Obesity-Related Inflammation in Adipose Tissue: Comparison of Activation of PPARα, PPARγ, and Their Combination

Atsushi Tsuchida, Toshimasa Yamauchi, Sato Takekawa, Yusuke Hada, Yusuke Ito, Toshiyuki Maki, Takashi Kadowaki
Journal: Diabetes
Diabetes 2005;54(12):3358–3370
https://doi.org/10.2337/diabetes.54.12.3358
Published: 01 December 2005
View articletitled, Peroxisome Proliferator–Activated Receptor (PPAR)α Activation Increases Adiponectin Receptors and Reduces Obesity-Related Inflammation in Adipose Tissue: Comparison of Activation of PPARα, PPARγ, and Their Combination
Open the PDF for Peroxisome Proliferator–Activated Receptor (PPAR)α Activation Increases Adiponectin Receptors and Reduces Obesity-Related Inflammation in Adipose Tissue: Comparison of Activation of PPARα, PPARγ, and Their Combination in another window
Journal Articles

Pioglitazone Reduces Islet Triglyceride Content and Restores Impaired Glucose-Stimulated Insulin Secretion in Heterozygous Peroxisome Proliferator–Activated Receptor-γ–Deficient Mice on a High-Fat Diet

Junji Matsui, Yasuo Terauchi, Naoto Kubota, Iseki Takamoto, Kazuhiro Eto, Tokuyuki Yamashita, Kajuro Komeda, Toshimasa Yamauchi, Junji Kamon, Shunbun Kita, Mitsuhiko Noda, Takashi Kadowaki
Journal: Diabetes
Diabetes 2004;53(11):2844–2854
https://doi.org/10.2337/diabetes.53.11.2844
Published: 01 November 2004
View articletitled, Pioglitazone Reduces Islet Triglyceride Content and Restores Impaired Glucose-Stimulated Insulin Secretion in Heterozygous Peroxisome Proliferator–Activated Receptor-γ–Deficient Mice on a High-Fat Diet
Open the PDF for Pioglitazone Reduces Islet Triglyceride Content and Restores Impaired Glucose-Stimulated Insulin Secretion in Heterozygous Peroxisome Proliferator–Activated Receptor-γ–Deficient Mice on a High-Fat Diet in another window