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Journal Articles

Lrtm1 - A Novel Sensor of Insulin Signaling and Regulator of Metabolism and Activity

Yingying Yu, Guoxiao Wang, Wenqiang Chen, Xiangyu Liu, Vitor Rosetto Munoz, Weikang Cai, Antonio S. Gomes, C. Ronald Kahn

Diabetes db241031

https://doi.org/10.2337/db24-1031

Published: 07 February 2025

View articletitled, Lrtm1 - A Novel Sensor of Insulin Signaling and Regulator of Metabolism and Activity

Meeting Abstracts

190-OR: Lrtm1, a Novel Regulator of Insulin Signaling and Metabolism

GUOXIAO WANG, YINGYING YU, WENQIANG CHEN, WEIKANG CAI, XIANGYU LIU, C. RONALD KAHN

Diabetes 2023;72(Supplement_1):190-OR

https://doi.org/10.2337/db23-190-OR

Published: 20 June 2023

View articletitled, 190-OR: Lrtm1, a Novel Regulator of Insulin Signaling and Metabolism

Meeting Abstracts

229-OR: Role of Insulin Signaling in the Regulation of Proteostasis in Astrocytes

SHAWN GEFFKEN, CATHERINE SMITH, HIU HAM LEE, WEIKANG CAI

Diabetes 2022;71(Supplement_1):229-OR

https://doi.org/10.2337/db22-229-OR

Published: 01 June 2022

View articletitled, 229-OR: Role of Insulin Signaling in the Regulation of Proteostasis in Astrocytes

Meeting Abstracts

223-OR: ADA Presidents' Select Abstract: Novel Ligand and Kinase-Independent Signaling by the Insulin Receptor

HIROFUMI NAGAO, WEIKANG CAI, HUI PAN, THIAGO M. BATISTA, BRUNA BRANDAO, C. RONALD KAHN

Diabetes 2022;71(Supplement_1):223-OR

https://doi.org/10.2337/db22-223-OR

Published: 01 June 2022

View articletitled, 223-OR: ADA Presidents' Select Abstract: Novel Ligand and Kinase-Independent Signaling by the Insulin Receptor

Journal Articles

Peripheral Insulin Regulates a Broad Network of Gene Expression in Hypothalamus, Hippocampus, and Nucleus Accumbens

Weikang Cai, Xuemei Zhang, Thiago M. Batista, Rubén García-Martín, Samir Softic, Guoxiao Wang, Alfred K. Ramirez, Masahiro Konishi, Brian T. O’Neill, Jong Hun Kim, Jason K. Kim, C. Ronald Kahn

Diabetes 2021;70(8):1857–1873

https://doi.org/10.2337/db20-1119

Published: 24 May 2021

View articletitled, Peripheral Insulin Regulates a Broad Network of Gene Expression in Hypothalamus, Hippocampus, and Nucleus Accumbens

Journal Articles

Muscle-Specific Insulin Receptor Overexpression Protects Mice From Diet-Induced Glucose Intolerance but Leads to Postreceptor Insulin Resistance

Guoxiao Wang, Yingying Yu, Weikang Cai, Thiago M. Batista, Sujin Suk, Hye Lim Noh, Michael Hirshman, Pasquale Nigro, Mengyao Ella Li, Samir Softic, Laurie Goodyear, Jason K. Kim, C. Ronald Kahn

Diabetes 2020;69(11):2294–2309

https://doi.org/10.2337/db20-0439

Published: 31 August 2020

View articletitled, Muscle-Specific Insulin Receptor Overexpression Protects Mice From Diet-Induced Glucose Intolerance but Leads to Postreceptor Insulin Resistance

Meeting Abstracts

1737-P: Defining Distinct Actions of Insulin and IGF1 Receptors and Their Extra and Intracellular Domains at the Level of the Phosphoproteome

HIROFUMI NAGAO, WEIKANG CAI, THIAGO M. BATISTA, HUI PAN, JONATHAN DREYFUSS, C. RONALD KAHN

Diabetes 2020;69(Supplement_1):1737-P

https://doi.org/10.2337/db20-1737-P

Published: 01 June 2020

View articletitled, 1737-P: Defining Distinct Actions of Insulin and IGF1 Receptors and Their Extra and Intracellular Domains at the Level of the Phosphoproteome

Meeting Abstracts

291-OR: Exercise Modulates Glucose Metabolism in Part through Changes in the Gut Microbiome

BRUNA BRANDAO, MENGYAO E. LI, WEIKANG CAI, THIAGO M. BATISTA, MICHAEL F. HIRSHMAN, LAURIE J. GOODYEAR, C. RONALD KAHN

Diabetes 2019;68(Supplement_1):291-OR

https://doi.org/10.2337/db19-291-OR

Published: 01 June 2019

View articletitled, 291-OR: Exercise Modulates Glucose Metabolism in Part through Changes in the Gut Microbiome

Meeting Abstracts

1785-P: Mice with Muscle-Specific Insulin Receptor Overexpression Are Protected from Diet-Induced Obesity and Glucose Intolerance but Develop Post-Receptor Insulin Resistance

GUOXIAO WANG, WEIKANG CAI, THIAGO M. BATISTA, SAMIR SOFTIC, C. RONALD KAHN

Diabetes 2019;68(Supplement_1):1785-P

https://doi.org/10.2337/db19-1785-P

Published: 01 June 2019

View articletitled, 1785-P: Mice with Muscle-Specific Insulin Receptor Overexpression Are Protected from Diet-Induced Obesity and Glucose Intolerance but Develop Post-Receptor Insulin Resistance

Meeting Abstracts

1805-P: Insulin Regulates a Broad Network of Gene Expression in the Brain to Regulated Brain Metabolism and Neurotransmission

WEIKANG CAI, THIAGO M. BATISTA, RUBEN GARCIA MARTIN, ALFRED RAMIREZ, MASAHIRO KONISHI, O'NEILL BRIAN T., JASON K. KIM, C. RONALD KAHN

Diabetes 2019;68(Supplement_1):1805-P

https://doi.org/10.2337/db19-1805-P

Published: 01 June 2019

View articletitled, 1805-P: Insulin Regulates a Broad Network of Gene Expression in the Brain to Regulated Brain Metabolism and Neurotransmission

Meeting Abstracts

35-OR: Physiological Insulin Regulates Alternative mRNA Splicing in Liver and Muscle at Multiple Levels

THIAGO M. BATISTA, WEIKANG CAI, BRUNA BRANDAO, C. RONALD KAHN

Diabetes 2019;68(Supplement_1):35-OR

https://doi.org/10.2337/db19-35-OR

Published: 01 June 2019

View articletitled, 35-OR: Physiological Insulin Regulates Alternative mRNA Splicing in Liver and Muscle at Multiple Levels

Meeting Abstracts

Insulin Acutely Regulates Gene Expression in Brain–A New Potential Major Level of Control of Metabolism and Neurotransmission

WEIKANG CAI, ALFRED RAMIREZ, JONATHAN DREYFUSS, THIAGO M. BATISTA, RUBEN GARCIA MARTIN, HUI PAN, MENGYAO E. LI, BRIAN T. O'NEILL, JASON K. KIM, C. RONALD KAHN

Diabetes 2018;67(Supplement_1):1792-P

https://doi.org/10.2337/db18-1792-P

Published: 01 July 2018

View articletitled, Insulin Acutely Regulates Gene Expression in Brain–A New Potential Major Level of Control of Metabolism and Neurotransmission

Meeting Abstracts

IGFBP2 Is Increased after Gastric Bypass in Humans—Potential Impact on Hepatic Metabolism

YIXING YUCHI, WEIKANG CAI, TOKIYO TAKAGI, HUI PAN, JONATHAN DREYFUSS, KATHLEEN FOSTER, ASHLEY H. VERNON, DONALD C. SIMONSON, ALLISON GOLDFINE, ANDREAS HOEFLICH, MARY E. PATTI

Diabetes 2018;67(Supplement_1):1833-P

https://doi.org/10.2337/db18-1833-P

Published: 01 July 2018

View articletitled, IGFBP2 Is Increased after Gastric Bypass in Humans—Potential Impact on Hepatic Metabolism

Meeting Abstracts

Dissection of Insulin-Dependent Pathways in Skeletal Muscle under Physiological and Diabetic Conditions

THIAGO M. BATISTA, RUBEN GARCIA MARTIN, WEIKANG CAI, SUJIN SUK, HYE LIM NOH, JASON K. KIM, C. RONALD KAHN

Diabetes 2018;67(Supplement_1):1785-P

https://doi.org/10.2337/db18-1785-P

Published: 01 July 2018

View articletitled, Dissection of Insulin-Dependent Pathways in Skeletal Muscle under Physiological and Diabetic Conditions

Meeting Abstracts

Sirt5 Plays a Critical Role in Mitochondrial Protein Acylation and Mitochondrial Metabolic Homeostasis in Brown Fat

GUOXIAO WANG, JESSE G. MEYER, WEIKANG CAI, MENGYAO E. LI, SAMIR SOFTIC, C. RONALD KAHN

Diabetes 2018;67(Supplement_1):274-OR

https://doi.org/10.2337/db18-274-OR

Published: 01 July 2018

View articletitled, Sirt5 Plays a Critical Role in Mitochondrial Protein Acylation and Mitochondrial Metabolic Homeostasis in Brown Fat

Meeting Abstracts

FoxK1/K2 Are New, Important Components of IR and IGF1R Signaling and Control of Cell Proliferation and Metabolism

MASAJI SAKAGUCHI, WEIKANG CAI, CHIH-HAO WANG, THIAGO M. BATISTA, EIICHI ARAKI, C. RONALD KAHN

Diabetes 2018;67(Supplement_1):356-OR

https://doi.org/10.2337/db18-356-OR

Published: 01 July 2018

View articletitled, FoxK1/K2 Are New, Important Components of IR and IGF1R Signaling and Control of Cell Proliferation and Metabolism

Journal Articles

Insulin Action in Brain Regulates Systemic Metabolism and Brain Function

André Kleinridders, Heather A. Ferris, Weikang Cai, C. Ronald Kahn

Diabetes 2014;63(7):2232–2243

https://doi.org/10.2337/db14-0568

Published: 14 June 2014

View articletitled, Insulin Action in Brain Regulates Systemic Metabolism and Brain Function

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Lrtm1 - A Novel Sensor of Insulin Signaling and Regulator of Metabolism and Activity

190-OR: Lrtm1, a Novel Regulator of Insulin Signaling and Metabolism

229-OR: Role of Insulin Signaling in the Regulation of Proteostasis in Astrocytes

223-OR: ADA Presidents' Select Abstract: Novel Ligand and Kinase-Independent Signaling by the Insulin Receptor

Peripheral Insulin Regulates a Broad Network of Gene Expression in Hypothalamus, Hippocampus, and Nucleus Accumbens

Muscle-Specific Insulin Receptor Overexpression Protects Mice From Diet-Induced Glucose Intolerance but Leads to Postreceptor Insulin Resistance

1737-P: Defining Distinct Actions of Insulin and IGF1 Receptors and Their Extra and Intracellular Domains at the Level of the Phosphoproteome

291-OR: Exercise Modulates Glucose Metabolism in Part through Changes in the Gut Microbiome

1785-P: Mice with Muscle-Specific Insulin Receptor Overexpression Are Protected from Diet-Induced Obesity and Glucose Intolerance but Develop Post-Receptor Insulin Resistance

1805-P: Insulin Regulates a Broad Network of Gene Expression in the Brain to Regulated Brain Metabolism and Neurotransmission

35-OR: Physiological Insulin Regulates Alternative mRNA Splicing in Liver and Muscle at Multiple Levels

Insulin Acutely Regulates Gene Expression in Brain–A New Potential Major Level of Control of Metabolism and Neurotransmission

IGFBP2 Is Increased after Gastric Bypass in Humans—Potential Impact on Hepatic Metabolism

Dissection of Insulin-Dependent Pathways in Skeletal Muscle under Physiological and Diabetic Conditions

Sirt5 Plays a Critical Role in Mitochondrial Protein Acylation and Mitochondrial Metabolic Homeostasis in Brown Fat

FoxK1/K2 Are New, Important Components of IR and IGF1R Signaling and Control of Cell Proliferation and Metabolism

Insulin Action in Brain Regulates Systemic Metabolism and Brain Function

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