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William L. Holland
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Journal Articles

Placing a Hex on Glucose Uptake

Faith M. Bowman, Scott A. Summers, William L. Holland
Journal: Diabetes
Diabetes 2023;72(6):690–692
DOI: https://doi.org/10.2337/dbi22-0040
Published: 19 May 2023
View article titled, Placing a Hex on Glucose Uptake
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Meeting Abstracts

252-LB: GRK2 Participates in Islet Function and Glucose-Stimulated Insulin Secretory Responses

JONATHAN W. SNYDER, SARAH K. MONTGOMERY, NICOLAI M. DOLIBA, JEFFREY ROMAN, YUZHEN TIAN, PRISCILA Y. SATO, WILLIAM L. HOLLAND, RAN HEE CHOI
Journal: Diabetes
Diabetes 2022;71(Supplement_1):252-LB
DOI: https://doi.org/10.2337/db22-252-LB
Published: 01 June 2022
View article titled, 252-LB: GRK2 Participates in Islet Function and Glucose-Stimulated Insulin Secretory Responses
Journal Articles

Very-Long-Chain Unsaturated Sphingolipids Mediate Oleate-Induced Rat β-Cell Proliferation

Anne-Laure Castell, Alexis Vivoli, Trevor S. Tippetts, Isabelle Robillard Frayne, Zuraya Elisa Angeles, Valentine S. Moullé, Scott A. Campbell, Matthieu Ruiz, Julien Ghislain, Christine Des Rosiers, William L. Holland, Scott A. Summers, Vincent Poitout
Journal: Diabetes
Diabetes 2022;71(6):1218–1232
DOI: https://doi.org/10.2337/db21-0640
Published: 14 March 2022
View article titled, Very-Long-Chain Unsaturated Sphingolipids Mediate Oleate-Induced Rat β-Cell Proliferation
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Journal Articles

A Novel Model of Diabetic Complications: Adipocyte Mitochondrial Dysfunction Triggers Massive β-Cell Hyperplasia

Christine M. Kusminski, Alexandra L. Ghaben, Thomas S. Morley, Ricardo J. Samms, Andrew C. Adams, Yu An, Joshua A. Johnson, Nolwenn Joffin, Toshiharu Onodera, Clair Crewe, William L. Holland, Ruth Gordillo, Philipp E. Scherer
Journal: Diabetes
Diabetes 2020;69(3):313–330
DOI: https://doi.org/10.2337/db19-0327
Published: 27 December 2020
View article titled, A Novel Model of Diabetic Complications: Adipocyte Mitochondrial Dysfunction Triggers Massive β-Cell Hyperplasia
Click here to open pdf in another window PDF for A Novel Model of Diabetic Complications: Adipocyte Mitochondrial Dysfunction Triggers Massive β-Cell Hyperplasia
Includes: Supplementary data
Journal Articles

Strong Heart, Low Ceramides

William L. Holland, Scott A. Summers
Journal: Diabetes
Diabetes 2018;67(8):1457–1460
DOI: https://doi.org/10.2337/dbi18-0018
Published: 13 July 2018
View article titled, Strong Heart, Low Ceramides
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Journal Articles

Ceramide-Initiated Protein Phosphatase 2A Activation Contributes to Arterial Dysfunction In Vivo

Leena P. Bharath, Ting Ruan, Youyou Li, Anindita Ravindran, Xin Wan, Jennifer Kim Nhan, Matthew Lewis Walker, Lance Deeter, Rebekah Goodrich, Elizabeth Johnson, Derek Munday, Robert Mueller, David Kunz, Deborah Jones, Van Reese, Scott A. Summers, Pon Velayutham Anandh Babu, William L. Holland, Quan-Jiang Zhang, E. Dale Abel, J. David Symons
Journal: Diabetes
Diabetes 2015;64(11):3914–3926
DOI: https://doi.org/10.2337/db15-0244
Published: 07 August 2015
View article titled, Ceramide-Initiated Protein Phosphatase 2A Activation Contributes to Arterial Dysfunction In Vivo
Click here to open pdf in another window PDF for Ceramide-Initiated Protein Phosphatase 2A Activation Contributes to Arterial Dysfunction In Vivo
Includes: Supplementary data
Journal Articles

Ceramide Mediates Vascular Dysfunction in Diet-Induced Obesity by PP2A-Mediated Dephosphorylation of the eNOS-Akt Complex

Quan-Jiang Zhang, William L. Holland, Lloyd Wilson, Jason M. Tanner, Devin Kearns, Judd M. Cahoon, Dix Pettey, Jason Losee, Bradlee Duncan, Derrick Gale, Christopher A. Kowalski, Nicholas Deeter, Alexandrea Nichols, Michole Deesing, Colton Arrant, Ting Ruan, Christoph Boehme, Dane R. McCamey, Janvida Rou, Kapil Ambal, Krishna K. Narra, Scott A. Summers, E. Dale Abel, J. David Symons
Journal: Diabetes
Diabetes 2012;61(7):1848–1859
DOI: https://doi.org/10.2337/db11-1399
Published: 15 June 2012
View article titled, Ceramide Mediates Vascular Dysfunction in Diet-Induced Obesity by PP2A-Mediated Dephosphorylation of the eNOS-Akt Complex
Click here to open pdf in another window PDF for Ceramide Mediates Vascular Dysfunction in Diet-Induced Obesity by PP2A-Mediated Dephosphorylation of the eNOS-Akt Complex
Includes: Supplementary data
Journal Articles

Ablation of AMP-Activated Protein Kinase α2 Activity Exacerbates Insulin Resistance Induced by High-Fat Feeding of Mice

Nobuharu Fujii, Richard C. Ho, Yasuko Manabe, Niels Jessen, Taro Toyoda, William L. Holland, Scott A. Summers, Michael F. Hirshman, Laurie J. Goodyear
Journal: Diabetes
Diabetes 2008;57(11):2958–2966
DOI: https://doi.org/10.2337/db07-1187
Published: 01 November 2008
View article titled, Ablation of AMP-Activated Protein Kinase α2 Activity Exacerbates Insulin Resistance Induced by High-Fat Feeding of Mice
Click here to open pdf in another window PDF for Ablation of AMP-Activated Protein Kinase α2 Activity Exacerbates Insulin Resistance Induced by High-Fat Feeding of Mice