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Journal Articles

Mutations of NRG4 Contribute to the Pathogenesis of Nonalcoholic Fatty Liver Disease and Related Metabolic Disorders

Yangyang Li, Li Jin, Feng Jiang, Jing Yan, Yan Lu, Qing Yang, Yi Zhang, Hong Zhang, Hairong Yu, Yuemei Zhang, Zhen He, Rong Zhang, Jianjun Yang, Cheng Hu
Journal: Diabetes
Diabetes 2021;70(10):2213–2224
DOI: https://doi.org/10.2337/db21-0064
Published: 14 July 2021
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Meeting Abstracts

235-OR: Dorzagliatin as a Glucose Sensitizer Achieved Sustained Glycemic Control with Good Safety Profiles in Drug-Naïve T2D Patients in a 52-Week Phase 3 Monotherapy Trial (SEED)

LI CHEN, YI ZHANG, DALONG ZHU
Journal: Diabetes
Diabetes 2021;70(Supplement_1):235-OR
DOI: https://doi.org/10.2337/db21-235-OR
Published: 01 June 2021
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Meeting Abstracts

763-P: Dorzagliatin Add-On to Metformin Achieved Sustained Efficacy and Good Safety Profiles in T2D Patients in a 52-Week Phase 3 Trial (DAWN)

LI CHEN, YI ZHANG, WENYING YANG
Journal: Diabetes
Diabetes 2021;70(Supplement_1):763-P
DOI: https://doi.org/10.2337/db21-763-P
Published: 01 June 2021
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Meeting Abstracts

182-OR: A Novel Dual-Acting Glucokinase Activator (GKA) Dorzagliatin (HMS5552) Achieved Primary Efficacy Endpoint with Good Safety Profiles in T2DM Patients after 24 Weeks of Treatment in a Phase III Monotherapy Trial

DALONG ZHU, YI ZHANG, LI CHEN
Journal: Diabetes
Diabetes 2020;69(Supplement_1):182-OR
DOI: https://doi.org/10.2337/db20-182-OR
Published: 01 June 2020
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Journal Articles

Exosomes Derived From Schwann Cells Ameliorate Peripheral Neuropathy in Type 2 Diabetic Mice

Lei Wang, Michael Chopp, Alexandra Szalad, XueRong Lu, Yi Zhang, Xinli Wang, Pasquale Cepparulo, Mei Lu, Chao Li, Zheng Gang Zhang
Journal: Diabetes
Diabetes 2020;69(4):749–759
DOI: https://doi.org/10.2337/db19-0432
Published: 08 January 2020
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Includes: Supplementary data
Meeting Abstracts

1158-P: Type 2 Diabetes Patients Subtype Analysis: Unbiased Machine Learning for Future Personalized T2D Care

LI CHEN, LINGGE FENG, CUI TANG, YI ZHANG
Journal: Diabetes
Diabetes 2019;68(Supplement_1):1158-P
DOI: https://doi.org/10.2337/db19-1158-P
Published: 01 June 2019
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Meeting Abstracts

Identification of Gastric Mucosa Key Pathways and Genes in Obesity and Obesity-Related Diabetes via Gene Microarray Analysis

XIN WEN, YI ZHANG, RUI J. WU, CUILING ZHU, RAN CUI, YOU HUI, FANG Y. MEI, JINGYANG GAO, SHEN QU, LE BU
Journal: Diabetes
Diabetes 2018;67(Supplement_1):1351-P
DOI: https://doi.org/10.2337/db18-1351-P
Published: 01 July 2018
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Meeting Abstracts

Pharmacodynamics Post-Hoc Analysis of Glucose Kinase Activator Dorzagliatin (HMS5552)—Twelve Weeks Treatment in T2D Patients in China

DALONG ZHU, YU ZHAO, CUI TANG, SR., HU TIANXIN, YONG-GUO LI, GUIYU ZHAO, XINGHUA HOU, SR., YI ZHANG, LI CHEN, HMM0201 STUDY GROUP
Journal: Diabetes
Diabetes 2018;67(Supplement_1):1201-P
DOI: https://doi.org/10.2337/db18-1201-P
Published: 01 July 2018
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Meeting Abstracts

No Drug–Drug Interaction between Dorzagliatin and Metformin in Type 2 Diabetes Patients

LI CHEN, GUIYU ZHAO, SHUANG REN, YI ZHANG, DANIEL DU
Journal: Diabetes
Diabetes 2018;67(Supplement_1):2310-PUB
DOI: https://doi.org/10.2337/db18-2310-PUB
Published: 01 July 2018
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Journal Articles

Amyloid-β Induces Hepatic Insulin Resistance In Vivo via JAK2

Yi Zhang, Ben Zhou, Bo Deng, Fang Zhang, Jingxia Wu, Yuangao Wang, Yingying Le, Qiwei Zhai
Journal: Diabetes
Diabetes 2013;62(4):1159–1166
DOI: https://doi.org/10.2337/db12-0670
Published: 14 March 2013
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Includes: Supplementary data
Journal Articles

Amyloid-β Induces Hepatic Insulin Resistance by Activating JAK2/STAT3/SOCS-1 Signaling Pathway

Yi Zhang, Ben Zhou, Fang Zhang, Jingxia Wu, Yanan Hu, Yang Liu, Qiwei Zhai
Journal: Diabetes
Diabetes 2012;61(6):1434–1443
DOI: https://doi.org/10.2337/db11-0499
Published: 14 May 2012
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Includes: Supplementary data
Journal Articles

WldS Enhances Insulin Transcription and Secretion via a SIRT1-Dependent Pathway and Improves Glucose Homeostasis

Jingxia Wu, Fang Zhang, Menghong Yan, Dongmei Wu, Qiujing Yu, Yi Zhang, Ben Zhou, Michael W. McBurney, Qiwei Zhai
Journal: Diabetes
Diabetes 2011;60(12):3197–3207
DOI: https://doi.org/10.2337/db11-0232
Published: 13 November 2011
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Includes: Supplementary data
Journal Articles

Synergy Between Leptin Therapy and a Seemingly Negligible Amount of Voluntary Wheel Running Prevents Progression of Dietary Obesity in Leptin-Resistant Rats

Alexandra Shapiro, Michael Matheny, Yi Zhang, Nihal Tümer, Kit-Yan Cheng, Enda Rogrigues, Sergei Zolotukhin, Philip J. Scarpace
Journal: Diabetes
Diabetes 2008;57(3):614–622
DOI: https://doi.org/10.2337/db07-0863
Published: 01 March 2008
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