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Meeting Abstracts

1736-P: Effect of Glucokinase Haploinsufficiency on Pancreatic Beta-Cell Function and Mass in High-Fat, High-Sucrose Diet-Fed Mice

IKUMI SHIGESAWA, AKINOBU NAKAMURA, YUKI YAMAUCHI, SHINICHIRO KAWATA, ASUKA MIYAZAKI, HIROSHI NOMOTO, HIRAKU KAMEDA, HIDEAKI MIYOSHI, YASUO TERAUCHI, TATSUYA ATSUMI

Diabetes 2023;72(Supplement_1):1736-P

https://doi.org/10.2337/db23-1736-P

Published: 20 June 2023

View articletitled, 1736-P: Effect of Glucokinase Haploinsufficiency on Pancreatic Beta-Cell Function and Mass in High-Fat, High-Sucrose Diet-Fed Mice

Journal Articles

Imeglimin Ameliorates β-Cell Apoptosis by Modulating the Endoplasmic Reticulum Homeostasis Pathway

Jinghe Li, Ryota Inoue, Yu Togashi, Tomoko Okuyama, Aoi Satoh, Mayu Kyohara, Kuniyuki Nishiyama, Takahiro Tsuno, Daisuke Miyashita, Tatsuya Kin, A.M. James Shapiro, Resilind Su Ern Chew, Adrian Kee Keong Teo, Seiichi Oyadomari, Yasuo Terauchi, Jun Shirakawa

Diabetes 2022;71(3):424–439

https://doi.org/10.2337/db21-0123

Published: 29 September 2021

View articletitled, Imeglimin Ameliorates β-Cell Apoptosis by Modulating the Endoplasmic Reticulum Homeostasis Pathway

Meeting Abstracts

780-P: Improved Mitochondrial Function by Luseogliflozin Prevents Pancreatic Beta-Cell Damage

YUKI YAMAUCHI, AKINOBU NAKAMURA, TAKASHI YOKOTA, KIYOHIKO TAKAHASHI, SHINICHIRO KAWATA, KAZUHISA TSUCHIDA, KAZUNO OMORI, HIROSHI NOMOTO, HIRAKU KAMEDA, KYUYONG CHO, TOSHIHISA ANZAI, SHINYA TANAKA, YASUO TERAUCHI, HIDEAKI MIYOSHI, TATSUYA ATSUMI

Diabetes 2021;70(Supplement_1):780-P

https://doi.org/10.2337/db21-780-P

Published: 01 June 2021

View articletitled, 780-P: Improved Mitochondrial Function by Luseogliflozin Prevents Pancreatic Beta-Cell Damage

Meeting Abstracts

453-P: Diabetes Knowledge Test Score Predicts HbA1c Levels after Discharge in Inpatients with Type 2 Diabetes

KAZUYA OKUBO, TAICHI MINAMI, AKIKO KAMEDA, TAKU YAMADA, HIROKO HIIRAGI, FUMINA YOSHIDA, MAYUKO TAKAHASHI, YOICHI SUZUKI, YASUO TERAUCHI

Diabetes 2021;70(Supplement_1):453-P

https://doi.org/10.2337/db21-453-P

Published: 01 June 2021

View articletitled, 453-P: Diabetes Knowledge Test Score Predicts HbA1c Levels after Discharge in Inpatients with Type 2 Diabetes

Meeting Abstracts

460-P: Eating Behavior among Inpatients with Type 2 Diabetes (T2D) Is Affected by Childhood Food Education

MAYUKO TAKAHASHI, TAICHI MINAMI, AKIKO KAMEDA, TAKU YAMADA, HIROKO HIIRAGI, FUMINA YOSHIDA, KAZUYA OKUBO, YASUO TERAUCHI

Diabetes 2021;70(Supplement_1):460-P

https://doi.org/10.2337/db21-460-P

Published: 01 June 2021

View articletitled, 460-P: Eating Behavior among Inpatients with Type 2 Diabetes (T2D) Is Affected by Childhood Food Education

Journal Articles

Glucokinase Inactivation Paradoxically Ameliorates Glucose Intolerance by Increasing β-Cell Mass in db/db Mice

Kazuno Omori, Akinobu Nakamura, Hideaki Miyoshi, Yuki Yamauchi, Shinichiro Kawata, Kiyohiko Takahashi, Naoyuki Kitao, Hiroshi Nomoto, Hiraku Kameda, Kyu Yong Cho, Yasuo Terauchi, Tatsuya Atsumi

Diabetes 2021;70(4):917–931

https://doi.org/10.2337/db20-0881

Published: 18 February 2021

View articletitled, Glucokinase Inactivation Paradoxically Ameliorates Glucose Intolerance by Increasing β-Cell Mass in db/db Mice

Journal Articles

Melanophilin Accelerates Insulin Granule Fusion without Predocking to the Plasma Membrane

Hao Wang, Kouichi Mizuno, Noriko Takahashi, Eri Kobayashi, Jun Shirakawa, Yasuo Terauchi, Haruo Kasai, Katsuhide Okunishi, Tetsuro Izumi

Diabetes 2020;69(12):2655–2666

https://doi.org/10.2337/db20-0069

Published: 29 November 2020

View articletitled, Melanophilin Accelerates Insulin Granule Fusion without Predocking to the Plasma Membrane

Meeting Abstracts

2084-P: Hepatic Fat Accumulation Underlies the Inability of Glucokinase Activator to Achieve a Sustained Hypoglycemic Effect in db/db Mice

SHINICHIRO KAWATA, AKINOBU NAKAMURA, HIDEAKI MIYOSHI, KAZUHISA TSUCHIDA, KAZUNO OMORI, KIYOHIKO TAKAHASHI, HIROSHI NOMOTO, HIRAKU KAMEDA, KYUYONG CHO, YASUO TERAUCHI, TATSUYA ATSUMI

Diabetes 2020;69(Supplement_1):2084-P

https://doi.org/10.2337/db20-2084-P

Published: 01 June 2020

View articletitled, 2084-P: Hepatic Fat Accumulation Underlies the Inability of Glucokinase Activator to Achieve a Sustained Hypoglycemic Effect in db/db Mice

Meeting Abstracts

2055-P: S100A8 Suppresses ß-Cell Proliferation in Diet-Induced Obese Mice

DAISUKE MIYASHITA, JUN SHIRAKAWA, YU TOGASHI, TOMOKO OKUYAMA, MAYU KYOHARA, YASUO TERAUCHI

Diabetes 2020;69(Supplement_1):2055-P

https://doi.org/10.2337/db20-2055-P

Published: 01 June 2020

View articletitled, 2055-P: S100A8 Suppresses ß-Cell Proliferation in Diet-Induced Obese Mice

Meeting Abstracts

2281-PUB: Quality of Life in Japanese Patients with Type 2 Diabetes Mellitus

KENICHIRO TAKAHASHI, YASUO TERAUCHI, TADASHI YAMAKAWA

Diabetes 2020;69(Supplement_1):2281-PUB

https://doi.org/10.2337/db20-2281-PUB

Published: 01 June 2020

View articletitled, 2281-PUB: Quality of Life in Japanese Patients with Type 2 Diabetes Mellitus

Meeting Abstracts

2268-PUB: Relationship between Serum Free Fatty Acid and Proinsulin Concentrations

KOKI CHIBA, AKINOBU NAKAMURA, HIDEAKI MIYOSHI, SHIGEKAZU UKAWA, KOSHI NAKAMURA, TAKAFUMI NAKAGAWA, YASUO TERAUCHI, AKIKO TAMAKOSHI, TATSUYA ATSUMI

Diabetes 2020;69(Supplement_1):2268-PUB

https://doi.org/10.2337/db20-2268-PUB

Published: 01 June 2020

View articletitled, 2268-PUB: Relationship between Serum Free Fatty Acid and Proinsulin Concentrations

Meeting Abstracts

1573-P: Inverse Association between Serum High-Molecular-Weight Adiponectin Level and Proinsulin Level in a General Japanese Population: DOSANCO Health Study

AKINOBU NAKAMURA, HIDEAKI MIYOSHI, SHIGEKAZU UKAWA, KOSHI NAKAMURA, TAKAFUMI NAKAGAWA, YASUO TERAUCHI, AKIKO TAMAKOSHI, TATSUYA ATSUMI

Diabetes 2020;69(Supplement_1):1573-P

https://doi.org/10.2337/db20-1573-P

Published: 01 June 2020

View articletitled, 1573-P: Inverse Association between Serum High-Molecular-Weight Adiponectin Level and Proinsulin Level in a General Japanese Population: DOSANCO Health Study

Meeting Abstracts

1497-P: Proinsulin as a Potential Marker of Early Pancreatic Beta-Cell Dysfunction

AKINOBU NAKAMURA, HIDEAKI MIYOSHI, SHIGEKAZU UKAWA, KOSHI NAKAMURA, TAKAFUMI NAKAGAWA, YASUO TERAUCHI, AKIKO TAMAKOSHI, TATSUYA ATSUMI

Diabetes 2019;68(Supplement_1):1497-P

https://doi.org/10.2337/db19-1497-P

Published: 01 June 2019

View articletitled, 1497-P: Proinsulin as a Potential Marker of Early Pancreatic Beta-Cell Dysfunction

Meeting Abstracts

113-LB: Effects of Liraglutide and Empagliflozin Add-On to Insulin Therapy in Patients with Type 2 Diabetes: ELLENA-IT, a Randomized Controlled Study

HIROTATSU NAKAGUCHI, YOSHINOBU KONDO, YASUO TERAUCHI

Diabetes 2019;68(Supplement_1):113-LB

https://doi.org/10.2337/db19-113-LB

Published: 01 June 2019

View articletitled, 113-LB: Effects of Liraglutide and Empagliflozin Add-On to Insulin Therapy in Patients with Type 2 Diabetes: ELLENA-IT, a Randomized Controlled Study

Meeting Abstracts

1060-P: Effect of Dulaglutide and Long-Acting Insulin Combination Therapy in Patients with Type 2 Diabetes

KOHEI ITO, SHINOBU SATOH, YOSHINOBU KONDO, YASUO TERAUCHI

Diabetes 2019;68(Supplement_1):1060-P

https://doi.org/10.2337/db19-1060-P

Published: 01 June 2019

View articletitled, 1060-P: Effect of Dulaglutide and Long-Acting Insulin Combination Therapy in Patients with Type 2 Diabetes

Meeting Abstracts

994-P: Effects of Dulaglutide and Trelagliptin on ß-Cell Function after One Year in Patients with Type 2 Diabetes: DUET-Beta Extension Study

YOSHINOBU KONDO, SHINOBU SATOH, YASUO TERAUCHI

Diabetes 2019;68(Supplement_1):994-P

https://doi.org/10.2337/db19-994-P

Published: 01 June 2019

View articletitled, 994-P: Effects of Dulaglutide and Trelagliptin on ß-Cell Function after One Year in Patients with Type 2 Diabetes: DUET-Beta Extension Study

Meeting Abstracts

1619-P: Risk Factors for Sleep Apnea Syndrome in Nonobese Type 2 Diabetics

SATSUKI KAWASAKI, HARUO MISAWA, TETSURI KONDO, YOSHINOBU KONDO, YASUO TERAUCHI

Diabetes 2019;68(Supplement_1):1619-P

https://doi.org/10.2337/db19-1619-P

Published: 01 June 2019

View articletitled, 1619-P: Risk Factors for Sleep Apnea Syndrome in Nonobese Type 2 Diabetics

Meeting Abstracts

1903-P: Protective Effects of Linagliptin on Hepatic Steatosis in Mice Treated with Dual Inhibitor for Insulin Receptor and IGF-1 Receptor

TOMOKO OKUYAMA, JUN SHIRAKAWA, YASUO TERAUCHI

Diabetes 2019;68(Supplement_1):1903-P

https://doi.org/10.2337/db19-1903-P

Published: 01 June 2019

View articletitled, 1903-P: Protective Effects of Linagliptin on Hepatic Steatosis in Mice Treated with Dual Inhibitor for Insulin Receptor and IGF-1 Receptor

Meeting Abstracts

1855-P: Effects of Dapagliflozin and/or Insulin Glargine on Hepatic Steatosis in db/db Mice

KAZUNO OMORI, AKINOBU NAKAMURA, HIDEAKI MIYOSHI, HIROSHI NOMOTO, HIRAKU KAMEDA, KYUYONG CHO, YASUO TERAUCHI, TATSUYA ATSUMI

Diabetes 2019;68(Supplement_1):1855-P

https://doi.org/10.2337/db19-1855-P

Published: 01 June 2019

View articletitled, 1855-P: Effects of Dapagliflozin and/or Insulin Glargine on Hepatic Steatosis in db/db Mice

Meeting Abstracts

2088-P: Soluble EGFR and Adipsin Are Independent Serum Biomarkers for Insulin Resistance in Mouse and Human

MAYU KYOHARA, JUN SHIRAKAWA, YASUO TERAUCHI

Diabetes 2019;68(Supplement_1):2088-P

https://doi.org/10.2337/db19-2088-P

Published: 01 June 2019

View articletitled, 2088-P: Soluble EGFR and Adipsin Are Independent Serum Biomarkers for Insulin Resistance in Mouse and Human

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1736-P: Effect of Glucokinase Haploinsufficiency on Pancreatic Beta-Cell Function and Mass in High-Fat, High-Sucrose Diet-Fed Mice

Imeglimin Ameliorates β-Cell Apoptosis by Modulating the Endoplasmic Reticulum Homeostasis Pathway

780-P: Improved Mitochondrial Function by Luseogliflozin Prevents Pancreatic Beta-Cell Damage

453-P: Diabetes Knowledge Test Score Predicts HbA1c Levels after Discharge in Inpatients with Type 2 Diabetes

460-P: Eating Behavior among Inpatients with Type 2 Diabetes (T2D) Is Affected by Childhood Food Education

Glucokinase Inactivation Paradoxically Ameliorates Glucose Intolerance by Increasing β-Cell Mass in db/db Mice

Melanophilin Accelerates Insulin Granule Fusion without Predocking to the Plasma Membrane

2084-P: Hepatic Fat Accumulation Underlies the Inability of Glucokinase Activator to Achieve a Sustained Hypoglycemic Effect in db/db Mice

2055-P: S100A8 Suppresses ß-Cell Proliferation in Diet-Induced Obese Mice

2281-PUB: Quality of Life in Japanese Patients with Type 2 Diabetes Mellitus

2268-PUB: Relationship between Serum Free Fatty Acid and Proinsulin Concentrations

1573-P: Inverse Association between Serum High-Molecular-Weight Adiponectin Level and Proinsulin Level in a General Japanese Population: DOSANCO Health Study

1497-P: Proinsulin as a Potential Marker of Early Pancreatic Beta-Cell Dysfunction

113-LB: Effects of Liraglutide and Empagliflozin Add-On to Insulin Therapy in Patients with Type 2 Diabetes: ELLENA-IT, a Randomized Controlled Study

1060-P: Effect of Dulaglutide and Long-Acting Insulin Combination Therapy in Patients with Type 2 Diabetes

994-P: Effects of Dulaglutide and Trelagliptin on ß-Cell Function after One Year in Patients with Type 2 Diabetes: DUET-Beta Extension Study

1619-P: Risk Factors for Sleep Apnea Syndrome in Nonobese Type 2 Diabetics

1903-P: Protective Effects of Linagliptin on Hepatic Steatosis in Mice Treated with Dual Inhibitor for Insulin Receptor and IGF-1 Receptor

1855-P: Effects of Dapagliflozin and/or Insulin Glargine on Hepatic Steatosis in db/db Mice

2088-P: Soluble EGFR and Adipsin Are Independent Serum Biomarkers for Insulin Resistance in Mouse and Human

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