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Meeting Abstracts

275-LB: Mitochondrial Fission Factor Can Be a Key Factor in the Regulation of Hepatic Lipid Metabolism

YUKINA TAKEICHI, TAKASHI MIYAZAWA, YOSHIHIRO OGAWA

Diabetes 2023;72(Supplement_1):275-LB

https://doi.org/10.2337/db23-275-LB

Published: 20 June 2023

View article titled, 275-LB: Mitochondrial Fission Factor Can Be a Key Factor in the Regulation of Hepatic Lipid Metabolism

Meeting Abstracts

257-LB: Defining the Stage-Dependent Transcriptome and Methylome in the Mouse Liver during Perinatal Metabolic Maturation

SEIICHI YANO, NAOICHI SATO, HIROMITSU ARAKI, FUMIHITO MIURA, TAKASHI ITO, YOSHIHIRO OGAWA

Diabetes 2023;72(Supplement_1):257-LB

https://doi.org/10.2337/db23-257-LB

Published: 20 June 2023

View article titled, 257-LB: Defining the Stage-Dependent Transcriptome and Methylome in the Mouse Liver during Perinatal Metabolic Maturation

Meeting Abstracts

252-LB: Dectin-2 Deficiency Promotes Proinflammatory Cytokine Release from Macrophages and Impairs Glucose-Stimulated Insulin Secretion

MASAMICHI FUJITA, TAKASHI MIYAZAWA, KEIICHIRO UCHIDA, NAOHIRO UCHIDA, TOMOMI HATAYAMA, SHINTARO NAKAMURA, YUKINA TAKEICHI, YASUTAKA MIYACHI, YOSHIHIRO OGAWA

Diabetes 2023;72(Supplement_1):252-LB

https://doi.org/10.2337/db23-252-LB

Published: 20 June 2023

View article titled, 252-LB: Dectin-2 Deficiency Promotes Proinflammatory Cytokine Release from Macrophages and Impairs Glucose-Stimulated Insulin Secretion

Meeting Abstracts

266-LB: SGLT2 Inhibition Improved Endurance Performance of db/db Mice Accompanied by an Increased Endogenous AMPK Activator in Skeletal Muscles

SHINTARO NAKAMURA, YASUTAKA MIYACHI, HISASHI YOKOMIZO, HIROKO OTSUKA, RYUICHI SAKAMOTO, MASATOMO TAKAHASHI, YOSHIHIRO IZUMI, TAKASHI MIYAZAWA, TAKESHI BAMBA, YOSHIHIRO OGAWA

Diabetes 2023;72(Supplement_1):266-LB

https://doi.org/10.2337/db23-266-LB

Published: 20 June 2023

View article titled, 266-LB: SGLT2 Inhibition Improved Endurance Performance of db/db Mice Accompanied by an Increased Endogenous AMPK Activator in Skeletal Muscles

Meeting Abstracts

2037-P: Islet ß-Cell Dedifferentiation Is Involved in Progression of Type 2 Diabetes

KIKUKO AMO-SHIINOKI, KATSUYA TANABE, RYOTARO BOUCHI, WATARU NISHIMURA, YOSHIHIRO OGAWA, YUKIO TANIZAWA

Diabetes 2020;69(Supplement_1):2037-P

https://doi.org/10.2337/db20-2037-P

Published: 01 June 2020

View article titled, 2037-P: Islet ß-Cell Dedifferentiation Is Involved in Progression of Type 2 Diabetes

Meeting Abstracts

1921-P: Nonalcoholic Steatohepatitis in Mice with Hepatocyte-Specific Deletion of Mitochondrial Fission Factor

YUKINA TAKEICHI, TAKASHI MIYAZAWA, SHOHEI SAKAMOTO, RYUICHI SAKAMOTO, MASATOSHI NOMURA, YOSHIHIRO OGAWA

Diabetes 2020;69(Supplement_1):1921-P

https://doi.org/10.2337/db20-1921-P

Published: 01 June 2020

View article titled, 1921-P: Nonalcoholic Steatohepatitis in Mice with Hepatocyte-Specific Deletion of Mitochondrial Fission Factor

Meeting Abstracts

231-LB: Importance of Intestinal Environment and Cellular Plasticity of Beta Cells in the Development of Post-Pancreatectomy Diabetes

RYOTARO BOUCHI, TATSUYA FUKUDA, TAKATO TAKEUCHI, KIKUKO AMO-SHIINOKI, KATSUYA TANABE, YUKIO TANIZAWA, TETSUYA YAMADA, YOSHIHIRO OGAWA

Diabetes 2020;69(Supplement_1):231-LB

https://doi.org/10.2337/db20-231-LB

Published: 01 June 2020

View article titled, 231-LB: Importance of Intestinal Environment and Cellular Plasticity of Beta Cells in the Development of Post-Pancreatectomy Diabetes

Meeting Abstracts

2009-P: Molecular Mechanisms of Obesity-Associated Vascular Vulnerability via Signals of Appetite Regulation

KENTARO MORI, KYOICHIRO TSUCHIYA, SUGURU NAKAMURA, KUMIKO SHIBA, YASUTAKA MIYACHI, YOSHIHIRO OGAWA, KENICHIRO KITAMURA

Diabetes 2019;68(Supplement_1):2009-P

https://doi.org/10.2337/db19-2009-P

Published: 01 June 2019

View article titled, 2009-P: Molecular Mechanisms of Obesity-Associated Vascular Vulnerability via Signals of Appetite Regulation

Meeting Abstracts

Poldip2 Affects Collagen I Accumulation by Regulating the Expression of Zyxin in Vascular Smooth Muscle Cells

MASAKAZU FUJII, NORIYUKI SONODA, MISATO OKAMOTO, HIDETAKA MORINAGA, YOSHIHIRO OGAWA, KATHY GRIENDLING

Diabetes 2018;67(Supplement_1):478-P

https://doi.org/10.2337/db18-478-P

Published: 01 July 2018

View article titled, Poldip2 Affects Collagen I Accumulation by Regulating the Expression of Zyxin in Vascular Smooth Muscle Cells

Meeting Abstracts

The Establishment of a Registry of Elderly Patients with Diabetes and an Investigation of the Inhibitory Factor of Cognitive Dysfunction

MISATO OKAMOTO, JUN ITOH, NORIYUKI SONODA, YASUTAKA MAEDA, MASAKAZU FUJII, YOSHIHIRO OGAWA

Diabetes 2018;67(Supplement_1):2372-PUB

https://doi.org/10.2337/db18-2372-PUB

Published: 01 July 2018

View article titled, The Establishment of a Registry of Elderly Patients with Diabetes and an Investigation of the Inhibitory Factor of Cognitive Dysfunction

Meeting Abstracts

Deficiency of Melanocortin 4 Receptor Promotes Vascular Vulnerability in Mice

KENTARO MORI, KYOICHIRO TSUCHIYA, SUGURU NAKAMURA, YASUTAKA MIYACHI, KUMIKO SHIBA, YOSHIHIRO OGAWA, KENICHIRO KITAMURA

Diabetes 2018;67(Supplement_1):1993-P

https://doi.org/10.2337/db18-1993-P

Published: 01 July 2018

View article titled, Deficiency of Melanocortin 4 Receptor Promotes Vascular Vulnerability in Mice

Journal Articles

Activation of SF1 Neurons in the Ventromedial Hypothalamus by DREADD Technology Increases Insulin Sensitivity in Peripheral Tissues

Eulalia A. Coutinho, Shiki Okamoto, Ayako Wendy Ishikawa, Shigefumi Yokota, Nobuhiro Wada, Takahiro Hirabayashi, Kumiko Saito, Tatsuya Sato, Kazuyo Takagi, Chen-Chi Wang, Kenta Kobayashi, Yoshihiro Ogawa, Seiji Shioda, Yumiko Yoshimura, Yasuhiko Minokoshi

Diabetes 2017;66(9):2372–2386

https://doi.org/10.2337/db16-1344

Published: 03 July 2017

View article titled, Activation of SF1 Neurons in the Ventromedial Hypothalamus by DREADD Technology Increases Insulin Sensitivity in Peripheral Tissues

Includes: Supplementary data

Journal Articles

SIK2 Is Critical in the Regulation of Lipid Homeostasis and Adipogenesis In Vivo

Jinyoung Park, Young-Sil Yoon, Hye-Sook Han, Yong-Hoon Kim, Yoshihiro Ogawa, Keun-Gyu Park, Chul-Ho Lee, Seong-Tae Kim, Seung-Hoi Koo

Diabetes 2014;63(11):3659–3673

https://doi.org/10.2337/db13-1423

Published: 13 October 2014

View article titled, SIK2 Is Critical in the Regulation of Lipid Homeostasis and Adipogenesis In Vivo

Includes: Supplementary data

Journal Articles

Ligand-Activated PPARα-Dependent DNA Demethylation Regulates the Fatty Acid β-Oxidation Genes in the Postnatal Liver

Tatsuya Ehara, Yasutomi Kamei, Xunmei Yuan, Mayumi Takahashi, Sayaka Kanai, Erina Tamura, Kazutaka Tsujimoto, Takashi Tamiya, Yoshimi Nakagawa, Hitoshi Shimano, Takako Takai-Igarashi, Izuho Hatada, Takayoshi Suganami, Koshi Hashimoto, Yoshihiro Ogawa

Diabetes 2015;64(3):775–784

https://doi.org/10.2337/db14-0158

Published: 13 October 2014

View article titled, Ligand-Activated PPARα-Dependent DNA Demethylation Regulates the Fatty Acid β-Oxidation Genes in the Postnatal Liver

Includes: Supplementary data

Journal Articles

Activating Transcription Factor 4 Links Metabolic Stress to Interleukin-6 Expression in Macrophages

Yorihiro Iwasaki, Takayoshi Suganami, Rumi Hachiya, Ibuki Shirakawa, Misa Kim-Saijo, Miyako Tanaka, Miho Hamaguchi, Takako Takai-Igarashi, Michikazu Nakai, Yoshihiro Miyamoto, Yoshihiro Ogawa

Diabetes 2014;63(1):152–161

https://doi.org/10.2337/db13-0757

Published: 13 December 2013

View article titled, Activating Transcription Factor 4 Links Metabolic Stress to Interleukin-6 Expression in Macrophages

Includes: Supplementary data

Journal Articles

Activin Receptor-Like Kinase 7 Suppresses Lipolysis to Accumulate Fat in Obesity Through Downregulation of Peroxisome Proliferator–Activated Receptor γ and C/EBPα

Satomi Yogosawa, Shin Mizutani, Yoshihiro Ogawa, Tetsuro Izumi

Diabetes 2013;62(1):115–123

https://doi.org/10.2337/db12-0295

Published: 13 December 2012

View article titled, Activin Receptor-Like Kinase 7 Suppresses Lipolysis to Accumulate Fat in Obesity Through Downregulation of Peroxisome Proliferator–Activated Receptor γ and C/EBPα

Includes: Supplementary data

Journal Articles

Role of DNA Methylation in the Regulation of Lipogenic Glycerol-3-Phosphate Acyltransferase 1 Gene Expression in the Mouse Neonatal Liver

Tatsuya Ehara, Yasutomi Kamei, Mayumi Takahashi, Xunmei Yuan, Sayaka Kanai, Erina Tamura, Miyako Tanaka, Tomomi Yamazaki, Shinji Miura, Osamu Ezaki, Takayoshi Suganami, Masaki Okano, Yoshihiro Ogawa

Diabetes 2012;61(10):2442–2450

https://doi.org/10.2337/db11-1834

Published: 13 September 2012

View article titled, Role of DNA Methylation in the Regulation of Lipogenic Glycerol-3-Phosphate Acyltransferase 1 Gene Expression in the Mouse Neonatal Liver

Includes: Supplementary data

Journal Articles

The Radioprotective 105/MD-1 Complex Contributes to Diet-Induced Obesity and Adipose Tissue Inflammation

Diabetes 2012;61(5):1199–1209

https://doi.org/10.2337/db11-1182

Published: 13 April 2012

View article titled, The Radioprotective 105/MD-1 Complex Contributes to Diet-Induced Obesity and Adipose Tissue Inflammation

Includes: Supplementary data

Journal Articles

Increased Expression of Macrophage-Inducible C-type Lectin in Adipose Tissue of Obese Mice and Humans

Masayuki Ichioka, Takayoshi Suganami, Naoto Tsuda, Ibuki Shirakawa, Yoichiro Hirata, Noriko Satoh-Asahara, Yuri Shimoda, Miyako Tanaka, Misa Kim-Saijo, Yoshihiro Miyamoto, Yasutomi Kamei, Masataka Sata, Yoshihiro Ogawa

Diabetes 2011;60(3):819–826

https://doi.org/10.2337/db10-0864

Published: 21 February 2011

View article titled, Increased Expression of Macrophage-Inducible C-type Lectin in Adipose Tissue of Obese Mice and Humans

Includes: Supplementary data

Journal Articles

Antiobesity Effect of Eicosapentaenoic Acid in High-Fat/High-Sucrose Diet–Induced Obesity: Importance of Hepatic Lipogenesis

Ayumi Sato, Hiroyuki Kawano, Tatsuto Notsu, Masahiko Ohta, Masanori Nakakuki, Kiyoshi Mizuguchi, Michiko Itoh, Takayoshi Suganami, Yoshihiro Ogawa

Diabetes 2010;59(10):2495–2504

https://doi.org/10.2337/db09-1554

Published: 03 August 2010

View article titled, Antiobesity Effect of Eicosapentaenoic Acid in High-Fat/High-Sucrose Diet–Induced Obesity: <subtitle>Importance of Hepatic Lipogenesis</subtitle>

Includes: Supplementary data

NARROW

275-LB: Mitochondrial Fission Factor Can Be a Key Factor in the Regulation of Hepatic Lipid Metabolism

257-LB: Defining the Stage-Dependent Transcriptome and Methylome in the Mouse Liver during Perinatal Metabolic Maturation

252-LB: Dectin-2 Deficiency Promotes Proinflammatory Cytokine Release from Macrophages and Impairs Glucose-Stimulated Insulin Secretion

266-LB: SGLT2 Inhibition Improved Endurance Performance of db/db Mice Accompanied by an Increased Endogenous AMPK Activator in Skeletal Muscles

2037-P: Islet ß-Cell Dedifferentiation Is Involved in Progression of Type 2 Diabetes

1921-P: Nonalcoholic Steatohepatitis in Mice with Hepatocyte-Specific Deletion of Mitochondrial Fission Factor

231-LB: Importance of Intestinal Environment and Cellular Plasticity of Beta Cells in the Development of Post-Pancreatectomy Diabetes

2009-P: Molecular Mechanisms of Obesity-Associated Vascular Vulnerability via Signals of Appetite Regulation

Poldip2 Affects Collagen I Accumulation by Regulating the Expression of Zyxin in Vascular Smooth Muscle Cells

The Establishment of a Registry of Elderly Patients with Diabetes and an Investigation of the Inhibitory Factor of Cognitive Dysfunction

Deficiency of Melanocortin 4 Receptor Promotes Vascular Vulnerability in Mice

Activation of SF1 Neurons in the Ventromedial Hypothalamus by DREADD Technology Increases Insulin Sensitivity in Peripheral Tissues

SIK2 Is Critical in the Regulation of Lipid Homeostasis and Adipogenesis In Vivo

Ligand-Activated PPARα-Dependent DNA Demethylation Regulates the Fatty Acid β-Oxidation Genes in the Postnatal Liver

Activating Transcription Factor 4 Links Metabolic Stress to Interleukin-6 Expression in Macrophages

Activin Receptor-Like Kinase 7 Suppresses Lipolysis to Accumulate Fat in Obesity Through Downregulation of Peroxisome Proliferator–Activated Receptor γ and C/EBPα

Role of DNA Methylation in the Regulation of Lipogenic Glycerol-3-Phosphate Acyltransferase 1 Gene Expression in the Mouse Neonatal Liver

The Radioprotective 105/MD-1 Complex Contributes to Diet-Induced Obesity and Adipose Tissue Inflammation

Increased Expression of Macrophage-Inducible C-type Lectin in Adipose Tissue of Obese Mice and Humans

Antiobesity Effect of Eicosapentaenoic Acid in High-Fat/High-Sucrose Diet–Induced Obesity: Importance of Hepatic Lipogenesis

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