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Meeting Abstracts

177-OR: Worsening Insulin Resistance Is Key Pathological Contributor to Dysglycemia in Lean Koreans—A Longitudinal Validation Study in the Korean Genome and Epidemiology Study (KoGES)

DOOHWA KIM, JINMI KIM, MYUNGSOO IM, SOREE RYANG, WOOK YI, MINSOO KIM, YEONG JIN KIM, IN JOO KIM, YOUNG JIN KIM, HYUK KANG, ARTHUR SHERMAN, STEPHANIE T. CHUNG, SANG SOO KIM, JOON HA
Journal: Diabetes
Diabetes 2023;72(Supplement_1):177-OR
https://doi.org/10.2337/db23-177-OR
Published: 20 June 2023
View article titled, 177-OR: Worsening Insulin Resistance Is Key Pathological Contributor to Dysglycemia in Lean Koreans—A Longitudinal Validation Study in the Korean Genome and Epidemiology Study (KoGES)
Meeting Abstracts

1268-P: One-Hour Glucose Thresholds for T2D Prediction—A Longitudinal Validation Study in the Korean Genome and Epidemiology Study (KoGES)

MYUNGSOO IM, SOREE RYANG, DOOHWA KIM, WOOK YI, JINMI KIM, HYUK KANG, YOUNG JIN KIM, YEONG JIN KIM, MINSOO KIM, IN JOO KIM, STEPHANIE T. CHUNG, ARTHUR SHERMAN, JOON HA, SANG SOO KIM
Journal: Diabetes
Diabetes 2023;72(Supplement_1):1268-P
https://doi.org/10.2337/db23-1268-P
Published: 20 June 2023
View article titled, 1268-P: One-Hour Glucose Thresholds for T2D Prediction—A Longitudinal Validation Study in the Korean Genome and Epidemiology Study (KoGES)
Meeting Abstracts

740-P: Six Subclasses with Glucose and Insulin Curves during OGTTs Capture Distinct Metabolic Characteristics and the Most Common Pathway to T2D in a Cohort of Koreans

JINMI KIM, WOOK YI, DOOHWA KIM, MYUNGSOO IM, SOREE RYANG, MINSOO KIM, YEONG JIN KIM, IN JOO KIM, YOUNG JIN KIM, HYUK KANG, STEPHANIE T. CHUNG, ARTHUR SHERMAN, SANG SOO KIM, JOON HA
Journal: Diabetes
Diabetes 2023;72(Supplement_1):740-P
https://doi.org/10.2337/db23-740-P
Published: 20 June 2023
View article titled, 740-P: Six Subclasses with Glucose and Insulin Curves during OGTTs Capture Distinct Metabolic Characteristics and the Most Common Pathway to T2D in a Cohort of Koreans
Meeting Abstracts

588-P: Model-Derived Beta-Cell Function and One-Hour Glucose Best Predict Future Diabetes in a 14-year Longitudinal Large Cohort Study in South Korea

SOREE RYANG, WOOK YI, JEONG MI KIM, SUHYEON BAE, SANGHUN JEONG, MINHEE JANG, MINSOO KIM, YEONG JIN KIM, IN JOO KIM, YOUNG JIN KIM, MINHA YOO, HARKSOO SONG, RUDA RHEE, JONG-HO KIM, HYUK KANG, ARTHUR SHERMAN, JINMI KIM, SANG SOO KIM, JOON HA
Journal: Diabetes
Diabetes 2021;70(Supplement_1):588-P
https://doi.org/10.2337/db21-588-P
Published: 01 June 2021
View article titled, 588-P: Model-Derived Beta-Cell Function and One-Hour Glucose Best Predict Future Diabetes in a 14-year Longitudinal Large Cohort Study in South Korea
Journal Articles

Depletion of Adipocyte Becn1 Leads to Lipodystrophy and Metabolic Dysregulation

Young Jin, Yul Ji, Yaechan Song, Sung Sik Choe, Yong Geun Jeon, Heeju Na, Tae Wook Nam, Hye Jeong Kim, Hahn Nahmgoong, Sung Min Kim, Jae-woo Kim, Ki Taek Nam, Je Kyung Seong, Daehee Hwang, Chan Bae Park, In Hye Lee, Jae Bum Kim, Han-Woong Lee
Journal: Diabetes
Diabetes 2021;70(1):182–195
https://doi.org/10.2337/db19-1239
Published: 12 October 2020
View article titled, Depletion of Adipocyte <em>Becn1</em> Leads to Lipodystrophy and Metabolic Dysregulation
Open the PDF for Depletion of Adipocyte <em>Becn1</em> Leads to Lipodystrophy and Metabolic Dysregulation in another window
Meeting Abstracts

1011-P: Therapeutic Potential of Novel Combination of a Long-Acting Glucagon Analog (HM15136) and Antidiabetic Drugs for the Treatment of Obesity

YOUNG JIN PARK, JONG SUK LEE, JUNG KUK KIM, DAEJIN KIM, YOUNG HOON KIM, YOUNG CHOI IN
Journal: Diabetes
Diabetes 2019;68(Supplement_1):1011-P
https://doi.org/10.2337/db19-1011-P
Published: 01 June 2019
View article titled, 1011-P: Therapeutic Potential of Novel Combination of a Long-Acting Glucagon Analog (HM15136) and Antidiabetic Drugs for the Treatment of Obesity
Meeting Abstracts

Replication of Previously Type 2 Diabetes Associated Loci in 35,000 Samples of Korean Population

YOUNG JIN KIM, MI YEONG HWANG, DONG MUN SHIN
Journal: Diabetes
Diabetes 2018;67(Supplement_1):215-LB
https://doi.org/10.2337/db18-215-LB
Published: 01 July 2018
View article titled, Replication of Previously Type 2 Diabetes Associated Loci in 35,000 Samples of Korean Population
Meeting Abstracts

Discovery and Replication of HDL-Associated Loci in the Korean Population Using 35,000 Individuals

BONG-JO KIM, YOUNG JIN KIM, MI YEONG HWANG, SANGHOON MOON
Journal: Diabetes
Diabetes 2018;67(Supplement_1):216-LB
https://doi.org/10.2337/db18-216-LB
Published: 01 July 2018
View article titled, Discovery and Replication of HDL-Associated Loci in the Korean Population Using 35,000 Individuals
Meeting Abstracts

Investigations into Tissue Distribution and Inhibition of Food Consumption with Efpeglenatide

YOUNG JIN PARK, IN YOUNG CHOI, MICHAEL E. TRAUTMANN, MARCUS HOMPESCH, CHRISTOPHER H. SORLI
Journal: Diabetes
Diabetes 2018;67(Supplement_1):1091-P
https://doi.org/10.2337/db18-1091-P
Published: 01 July 2018
View article titled, Investigations into Tissue Distribution and Inhibition of Food Consumption with Efpeglenatide
Journal Articles

Nonsynonymous Variants in PAX4 and GLP1R Are Associated With Type 2 Diabetes in an East Asian Population

Soo Heon Kwak, Jeesoo Chae, Seungbok Lee, Sungkyoung Choi, Bo Kyung Koo, Ji Won Yoon, Jin-Ho Park, Belong Cho, Min Kyong Moon, Soo Lim, Young Min Cho, Sanghoon Moon, Young Jin Kim, Sohee Han, Mi Yeong Hwang, Yoon Shin Cho, Myung-Shik Lee, Hak C. Jang, Hyun Min Kang, Taesung Park, Nam H. Cho, Kyunga Kim, Jong-Il Kim, Kyong Soo Park
Journal: Diabetes
Diabetes 2018;67(9):1892–1902
https://doi.org/10.2337/db18-0361
Published: 25 June 2018
View article titled, Nonsynonymous Variants in <em>PAX4</em> and <em>GLP1R</em> Are Associated With Type 2 Diabetes in an East Asian Population
Open the PDF for Nonsynonymous Variants in <em>PAX4</em> and <em>GLP1R</em> Are Associated With Type 2 Diabetes in an East Asian Population in another window
Includes: Supplementary data
Journal Articles

Genetically Determined Plasma Lipid Levels and Risk of Diabetic Retinopathy: A Mendelian Randomization Study

Lucia Sobrin, Yong He Chong, Qiao Fan, Alfred Gan, Lynn K. Stanwyck, Georgia Kaidonis, Jamie E. Craig, Jihye Kim, Wen-Ling Liao, Yu-Chuen Huang, Wen-Jane Lee, Yi-Jen Hung, Xiuqing Guo, Yang Hai, Eli Ipp, Samuela Pollack, Heather Hancock, Alkes Price, Alan Penman, Paul Mitchell, Gerald Liew, Albert V. Smith, Vilmundur Gudnason, Gavin Tan, Barbara E.K. Klein, Jane Kuo, Xiaohui Li, Mark W. Christiansen, Bruce M. Psaty, Kevin Sandow, Richard A. Jensen, Ronald Klein, Mary Frances Cotch, Jie Jin Wang, Yucheng Jia, Ching J. Chen, Yii-Der Ida Chen, Jerome I. Rotter, Fuu-Jen Tsai, Craig L. Hanis, Kathryn P. Burdon, Tien Yin Wong, Ching-Yu Cheng, Asian Genetic Epidemiology Network Consortium, Cassandra N. Spracklen, Peng Chen, Young Jin Kim, Xu Wang, Hui Cai, Shengxu Li, Jirong Long, Ying Wu, Ya-Xing Wang, Fumihiko Takeuchi, Jer-Yuarn Wu, Keum-Ji Jung, Cheng Hu, Koichi Akiyama, Yonghong Zhang, Sanghoon Moon, Todd A. Johnson, Huaixing Li, Rajkumar Dorajoo, Meian He, Maren E. Cannon, Tamara S. Roman, Elias Salfati, Keng-Hung Lin, Wayne H.H. Sheu, Devin Absher, Linda S. Adair, Themistocles L. Assimes, Tin Aung, Qiuyin Cai, Li-Ching Chang, Chien-Hsiun Chen, Li-Hsin Chien, Lee-Ming Chuang, Shu-Chun Chuang, Shufa Du, Cathy S.J. Fann, Alan B. Feranil, Yechiel Friedlander, Penny Gordon-Larsen, Dongfeng Gu, Lixuan Gui, Zhirong Guo, Chew-Kiat Heng, James Hixson, Xuhong Hou, Chao Agnes Hsiung, Yao Hu, Mi Yeong Hwang, Chii-Min Hwu, Masato Isono, Jyh-Ming Jimmy Juang, Chiea-Chuen Khor, Yun Kyoung Kim, Woon-Puay Koh, Michiaki Kubo, I-Te Lee, Sun-Ju Lee, Kae-Woei Liang, Blanche Lim, Sing-Hui Lim, Jianjun Liu, Toru Nabika, Wen-Harn Pan, Hao Peng, Thomas Quertermous, Charumathi Sabanayagam, Jinxiu Shi, Liang Sun, Pok Chien Tan, Shu-Pei Tan, Kent D. Taylor, Yik-Ying Teo, Sue-Anne Toh, Tatsuhiko Tsunoda, Rob M. van Dam, Aili Wang, Feijie Wang, Jie Wang, Wen Bin Wei, Yong-Bing Xiang, Jie Yao, Jian-Min Yuan, Rong Zhang, Wanting Zhao, Stephen S. Rich, Tzung-Dau Wang, Tangchun Wu, Xu Lin, Bok-Ghee Han, Toshihiro Tanaka, Yoon Shin Cho, Tomohiro Katsuya, Weiping Jia, Sun-Ha Jee, Yuan-Tsong Chen, Norihiro Kato, Jost B. Jonas, Xiao-Ou Shu, Jiang He, Wei Zheng, Wei Huang, Bong-Jo Kim, E-Shyong Tai, Karen L. Mohlke, Xueling Sim
Journal: Diabetes
Diabetes 2017;66(12):3130–3141
https://doi.org/10.2337/db17-0398
Published: 26 September 2017
View article titled, Genetically Determined Plasma Lipid Levels and Risk of Diabetic Retinopathy: A Mendelian Randomization Study
Open the PDF for Genetically Determined Plasma Lipid Levels and Risk of Diabetic Retinopathy: A Mendelian Randomization Study in another window
Includes: Supplementary data
Journal Articles

β-Lapachone Prevents Diet-Induced Obesity by Increasing Energy Expenditure and Stimulating the Browning of White Adipose Tissue via Downregulation of miR-382 Expression

Won Hee Choi, Jiyun Ahn, Chang Hwa Jung, Young Jin Jang, Tae Youl Ha
Journal: Diabetes
Diabetes 2016;65(9):2490–2501
https://doi.org/10.2337/db15-1423
Published: 31 May 2016
View article titled, β-Lapachone Prevents Diet-Induced Obesity by Increasing Energy Expenditure and Stimulating the Browning of White Adipose Tissue via Downregulation of miR-382 Expression
Open the PDF for β-Lapachone Prevents Diet-Induced Obesity by Increasing Energy Expenditure and Stimulating the Browning of White Adipose Tissue via Downregulation of miR-382 Expression in another window
Includes: Supplementary data
Journal Articles

Genome-Wide Association Meta-analysis Identifies Novel Variants Associated With Fasting Plasma Glucose in East Asians

Joo-Yeon Hwang, Xueling Sim, Ying Wu, Jun Liang, Yasuharu Tabara, Cheng Hu, Kazuo Hara, Claudia H.T. Tam, Qiuyin Cai, Qi Zhao, Sunha Jee, Fumihiko Takeuchi, Min Jin Go, Rick Twee Hee Ong, Takayoshi Ohkubo, Young Jin Kim, Rong Zhang, Toshimasa Yamauchi, Wing Yee So, Jirong Long, Dongfeng Gu, Nanette R. Lee, Soriul Kim, Tomohiro Katsuya, Ji Hee Oh, Jianjun Liu, Satoshi Umemura, Yeon-Jung Kim, Feng Jiang, Shiro Maeda, Juliana C.N. Chan, Wei Lu, James E. Hixson, Linda S. Adair, Keum Ji Jung, Toru Nabika, Jae-Bum Bae, Mi Hee Lee, Mark Seielstad, Terri L. Young, Yik Ying Teo, Yoshikuni Kita, Naoyuki Takashima, Haruhiko Osawa, So-Hyun Lee, Min-Ho Shin, Dong Hoon Shin, Bo Youl Choi, Jiajun Shi, Yu-Tang Gao, Yong-Bing Xiang, Wei Zheng, Norihiro Kato, Miwuk Yoon, Jiang He, Xiao Ou Shu, Ronald C.W. Ma, Takashi Kadowaki, Weiping Jia, Tetsuro Miki, Lu Qi, E Shyong Tai, Karen L. Mohlke, Bok-Ghee Han, Yoon Shin Cho, Bong-Jo Kim
Journal: Diabetes
Diabetes 2015;64(1):291–298
https://doi.org/10.2337/db14-0563
Published: 03 September 2014
View article titled, Genome-Wide Association Meta-analysis Identifies Novel Variants Associated With Fasting Plasma Glucose in East Asians
Open the PDF for Genome-Wide Association Meta-analysis Identifies Novel Variants Associated With Fasting Plasma Glucose in East Asians in another window
Includes: Supplementary data
Journal Articles

Multiple Nonglycemic Genomic Loci Are Newly Associated With Blood Level of Glycated Hemoglobin in East Asians

Peng Chen, Fumihiko Takeuchi, Jong-Young Lee, Huaixing Li, Jer-Yuarn Wu, Jun Liang, Jirong Long, Yasuharu Tabara, Mark O. Goodarzi, Mark A. Pereira, Young Jin Kim, Min Jin Go, Daniel O. Stram, Eranga Vithana, Chiea-Chuen Khor, Jianjun Liu, Jiemin Liao, Xingwang Ye, Yiqin Wang, Ling Lu, Terri L. Young, Jeannette Lee, Ah Chuan Thai, Ching-Yu Cheng, Rob M. van Dam, Yechiel Friedlander, Chew-Kiat Heng, Woon-Puay Koh, Chien-Hsiun Chen, Li-Ching Chang, Wen-Harn Pan, Qibin Qi, Masato Isono, Wei Zheng, Qiuyin Cai, Yutang Gao, Ken Yamamoto, Keizo Ohnaka, Ryoichi Takayanagi, Yoshikuni Kita, Hirotsugu Ueshima, Chao A. Hsiung, Jinrui Cui, Wayne H.-H. Sheu, Jerome I. Rotter, Yii-Der I. Chen, Chris Hsu, Yukinori Okada, Michiaki Kubo, Atsushi Takahashi, Toshihiro Tanaka, Frank J.A. van Rooij, Santhi K. Ganesh, Jinyan Huang, Tao Huang, Jianmin Yuan, Joo-Yeon Hwang, CHARGE Hematology Working Group, Myron D. Gross, Themistocles L. Assimes, Tetsuro Miki, Xiao-Ou Shu, Lu Qi, Yuan-Tson Chen, Xu Lin, Tin Aung, Tien-Yin Wong, Yik-Ying Teo, Bong-Jo Kim, Norihiro Kato, E-Shyong Tai
Journal: Diabetes
Diabetes 2014;63(7):2551–2562
https://doi.org/10.2337/db13-1815
Published: 14 June 2014
View article titled, Multiple Nonglycemic Genomic Loci Are Newly Associated With Blood Level of Glycated Hemoglobin in East Asians
Open the PDF for Multiple Nonglycemic Genomic Loci Are Newly Associated With Blood Level of Glycated Hemoglobin in East Asians in another window
Includes: Supplementary data