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Young-Bum Kim
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Meeting Abstracts

96-OR: Disruption of Leptin Receptor in Choroid Plexus Epithelial Cells Impairs Feeding Regulation and Weight Control

Free
KELLEN RODRIGUES, WON-MO YANG, JENNIE YOUNG, MINJIN LEE, FATIMA EZZAHA TIMZOURA, VINCENT PREVOT, YOUNG-BUM KIM
Journal: Diabetes
Diabetes 2025;74(Supplement_1):96-OR
https://doi.org/10.2337/db25-96-OR
Published: 20 June 2025
View article titled, 96-OR: Disruption of Leptin Receptor in Choroid Plexus Epithelial Cells Impairs Feeding Regulation and Weight Control
Meeting Abstracts

1603-P: ROCK1 in Hepatic Stellate Cells Regulates Insulin Sensitivity and Communicates with Muscle during Overnutrition

Free
KELLEN RODRIGUES, LIJUN ZHANG, JENNIE YOUNG, MINJIN LEE, YEJEE LIM, WON-MO YANG, PETRA HIRSOVA, YOUNG-BUM KIM
Journal: Diabetes
Diabetes 2025;74(Supplement_1):1603-P
https://doi.org/10.2337/db25-1603-P
Published: 20 June 2025
View article titled, 1603-P: ROCK1 in Hepatic Stellate Cells Regulates Insulin Sensitivity and Communicates with Muscle during Overnutrition
Meeting Abstracts

1540-P: LRP1 in GABAergic Neurons Is a Key Link between Obesity and Memory Function

Free
YOUNG-BUM KIM, KELLEN RODRIGUES, SEUNG CHAN KIM, CLARA CAMPOLIM, JENNIE YOUNG, WON-MO YANG
Journal: Diabetes
Diabetes 2024;73(Supplement_1):1540-P
https://doi.org/10.2337/db24-1540-P
Published: 14 June 2024
View article titled, 1540-P: LRP1 in GABAergic Neurons Is a Key Link between Obesity and Memory Function
Meeting Abstracts

1539-P: LRP1 Mediates Leptin Transport by Coupling with the Short-Form Leptin Receptor in the Choroid Plexus

Free
YOUNG-BUM KIM, WON-MO YANG, KELLEN RODRIGUES, SEUNG CHAN KIM, SHENGJIE FAN, JENNIE YOUNG
Journal: Diabetes
Diabetes 2024;73(Supplement_1):1539-P
https://doi.org/10.2337/db24-1539-P
Published: 14 June 2024
View article titled, 1539-P: LRP1 Mediates Leptin Transport by Coupling with the Short-Form Leptin Receptor in the Choroid Plexus
Meeting Abstracts

1761-P: MC4R-Expressing Neurons in the PVH Regulate Glycemia Independent of Insulin

Free
AYKUT G. UNER, HYON LEE, JUNG SUK HAN, RODRIGO M. PEREIRA, XIAOFANG SUN, HYUN JEONG KIM, YOUNG-BUM KIM
Journal: Diabetes
Diabetes 2020;69(Supplement_1):1761-P
https://doi.org/10.2337/db20-1761-P
Published: 01 June 2020
View article titled, 1761-P: MC4R-Expressing Neurons in the PVH Regulate Glycemia Independent of Insulin
Meeting Abstracts

1776-P: ROCK1 Deletion in Sim1-Expressing Neurons of the Hypothalamus Leads to Obesity Despite Hypophagia

Free
HYON LEE, JUNG SUK HAN, AYKUT G. UNER, SOO J. CHOI, RODRIGO M. PEREIRA, XIAOFANG SUN, HYUN JEONG KIM, YOUNG-BUM KIM
Journal: Diabetes
Diabetes 2020;69(Supplement_1):1776-P
https://doi.org/10.2337/db20-1776-P
Published: 01 June 2020
View article titled, 1776-P: ROCK1 Deletion in Sim1-Expressing Neurons of the Hypothalamus Leads to Obesity Despite Hypophagia
Meeting Abstracts

1879-P: Targeted Disruption of Muscle-Specific ROCK2 Results in Insulin Resistance In Vivo

Free
HYUN JEONG KIM, RODRIGO M. PEREIRA, AYKUT G. UNER, HYON LEE, YOUNG-BUM KIM
Journal: Diabetes
Diabetes 2020;69(Supplement_1):1879-P
https://doi.org/10.2337/db20-1879-P
Published: 01 June 2020
View article titled, 1879-P: Targeted Disruption of Muscle-Specific ROCK2 Results in Insulin Resistance In Vivo
Meeting Abstracts

277-LB: LRP1 Mediates the Transport of Leptin Across the Blood-CSF Barrier at the Choroid Plexus

Free
JI A SEO, MIN-CHEOL KANG, NATALIA FERREIRA MENDES, THIAGO ARAUJO, WON-MO YANG, YOUNG-BUM KIM
Journal: Diabetes
Diabetes 2019;68(Supplement_1):277-LB
https://doi.org/10.2337/db19-277-LB
Published: 01 June 2019
View article titled, 277-LB: LRP1 Mediates the Transport of Leptin Across the Blood-CSF Barrier at the Choroid Plexus
Meeting Abstracts

LRP1 Regulates Adiposity by Controlling Energy Balance in MC4R Neurons

Free
MIN-CHEOL KANG, JI A. SEO, HYUNSOO CHO, HYUNNA LEE, YOUNG-BUM KIM
Journal: Diabetes
Diabetes 2018;67(Supplement_1):2007-P
https://doi.org/10.2337/db18-2007-P
Published: 01 July 2018
View article titled, LRP1 Regulates Adiposity by Controlling Energy Balance in MC4R Neurons
Meeting Abstracts

Role of ROCK1 in Pancreatic ß Cells

Free
BYUNG-JUN SUNG, KYU YEON HUR, JAE HYEON KIM, YOUNG-BUM KIM, MOON-KYU LEE
Journal: Diabetes
Diabetes 2018;67(Supplement_1):196-OR
https://doi.org/10.2337/db18-196-OR
Published: 01 July 2018
View article titled, Role of ROCK1 in Pancreatic ß Cells
Journal Articles

SUMO-Specific Protease 2 (SENP2) Is an Important Regulator of Fatty Acid Metabolism in Skeletal Muscle

Free
Young Do Koo, Jin Woo Choi, Myungjin Kim, Sehyun Chae, Byung Yong Ahn, Min Kim, Byung Chul Oh, Daehee Hwang, Jae Hong Seol, Young-Bum Kim, Young Joo Park, Sung Soo Chung, Kyong Soo Park
Journal: Diabetes
Diabetes 2015;64(7):2420–2431
https://doi.org/10.2337/db15-0115
Published: 17 March 2015
View article titled, SUMO-Specific Protease 2 (SENP2) Is an Important Regulator of Fatty Acid Metabolism in Skeletal Muscle
Open the PDF for SUMO-Specific Protease 2 (SENP2) Is an Important Regulator of Fatty Acid Metabolism in Skeletal Muscle in another window
Includes: Supplementary data
Journal Articles

Hypothalamic Angptl4/Fiaf Is a Novel Regulator of Food Intake and Body Weight

Open Access
Hyun-Kyong Kim, Byung-Soo Youn, Mi-Seon Shin, Churl Namkoong, Kyeong Han Park, Ja Hyun Baik, Jae Bum Kim, Joong-Yeol Park, Ki-up Lee, Young-Bum Kim, Min-Seon Kim
Journal: Diabetes
Diabetes 2010;59(11):2772–2780
https://doi.org/10.2337/db10-0145
Published: 26 August 2010
View article titled, Hypothalamic Angptl4/Fiaf Is a Novel Regulator of Food Intake and Body Weight
Open the PDF for Hypothalamic Angptl4/Fiaf Is a Novel Regulator of Food Intake and Body Weight in another window
Journal Articles

Resistance to High-Fat Diet–Induced Obesity but Exacerbated Insulin Resistance in Mice Overexpressing Preadipocyte Factor-1 (Pref-1): A New Model of Partial Lipodystrophy

Free
Josep A. Villena, Cheol Soo Choi, Yuhui Wang, Sheene Kim, Yu-Jin Hwang, Young-Bum Kim, Gary Cline, Gerald I. Shulman, Hei Sook Sul
Journal: Diabetes
Diabetes 2008;57(12):3258–3266
https://doi.org/10.2337/db07-1739
Published: 01 December 2008
View article titled, Resistance to High-Fat Diet–Induced Obesity but Exacerbated Insulin Resistance in Mice Overexpressing Preadipocyte Factor-1 (Pref-1): A New Model of Partial Lipodystrophy
Open the PDF for Resistance to High-Fat Diet–Induced Obesity but Exacerbated Insulin Resistance in Mice Overexpressing Preadipocyte Factor-1 (Pref-1): A New Model of Partial Lipodystrophy in another window
Includes: Supplementary data
Journal Articles

Unraveling the Temporal Pattern of Diet-Induced Insulin Resistance in Individual Organs and Cardiac Dysfunction in c57bl/6 Mice

Free
So-Young Park, You-Ree Cho, Hyo-Jeong Kim, Takamasa Higashimori, Cheryl Danton, Mi-Kyung Lee, Asim Dey, Beverly Rothermel, Young-Bum Kim, April Kalinowski, Kerry S. Russell, Jason K. Kim
Journal: Diabetes
Diabetes 2005;54(12):3530–3540
https://doi.org/10.2337/diabetes.54.12.3530
Published: 01 December 2005
View article titled, Unraveling the Temporal Pattern of Diet-Induced Insulin Resistance in Individual Organs and Cardiac Dysfunction in c57bl/6 Mice
Open the PDF for Unraveling the Temporal Pattern of Diet-Induced Insulin Resistance in Individual Organs and Cardiac Dysfunction in c57bl/6 Mice in another window
Journal Articles

Cardiac-Specific Overexpression of Peroxisome Proliferator–Activated Receptor-α Causes Insulin Resistance in Heart and Liver

Free
So-Young Park, You-Ree Cho, Brian N. Finck, Hyo-Jeong Kim, Takamasa Higashimori, Eun-Gyoung Hong, Mi-Kyung Lee, Cheryl Danton, Swati Deshmukh, Gary W. Cline, Julie J. Wu, Anton M. Bennett, Beverly Rothermel, April Kalinowski, Kerry S. Russell, Young-Bum Kim, Daniel P. Kelly, Jason K. Kim
Journal: Diabetes
Diabetes 2005;54(9):2514–2524
https://doi.org/10.2337/diabetes.54.9.2514
Published: 01 September 2005
View article titled, Cardiac-Specific Overexpression of Peroxisome Proliferator–Activated Receptor-α Causes Insulin Resistance in Heart and Liver
Open the PDF for Cardiac-Specific Overexpression of Peroxisome Proliferator–Activated Receptor-α Causes Insulin Resistance in Heart and Liver in another window
Journal Articles

Differential Effects of Interleukin-6 and -10 on Skeletal Muscle and Liver Insulin Action In Vivo

Free
Hyo-Jeong Kim, Takamasa Higashimori, So-Young Park, Hyejeong Choi, Jianying Dong, Yoon-Jung Kim, Hye-Lim Noh, You-Ree Cho, Gary Cline, Young-Bum Kim, Jason K. Kim
Journal: Diabetes
Diabetes 2004;53(4):1060–1067
https://doi.org/10.2337/diabetes.53.4.1060
Published: 01 April 2004
View article titled, Differential Effects of Interleukin-6 and -10 on Skeletal Muscle and Liver Insulin Action In Vivo
Open the PDF for Differential Effects of Interleukin-6 and -10 on Skeletal Muscle and Liver Insulin Action In Vivo in another window
Journal Articles

Insulin-Stimulated Protein Kinase C λ/ζ Activity Is Reduced in Skeletal Muscle of Humans With Obesity and Type 2 Diabetes: Reversal With Weight Reduction

Free
Young-Bum Kim, Ko Kotani, Theodore P. Ciaraldi, Robert R. Henry, Barbara B. Kahn
Journal: Diabetes
Diabetes 2003;52(8):1935–1942
https://doi.org/10.2337/diabetes.52.8.1935
Published: 01 August 2003
View article titled, Insulin-Stimulated Protein Kinase C λ/ζ Activity Is Reduced in Skeletal Muscle of Humans With Obesity and Type 2 Diabetes: Reversal With Weight Reduction
Open the PDF for Insulin-Stimulated Protein Kinase C λ/ζ Activity Is Reduced in Skeletal Muscle of Humans With Obesity and Type 2 Diabetes: Reversal With Weight Reduction in another window
Journal Articles

Troglitazone but not Metformin Restores Insulin-Stimulated Phosphoinositide 3-Kinase Activity and Increases p110β Protein Levels in Skeletal Muscle of Type 2 Diabetic Subjects

Free
Young-Bum Kim, Theodore P. Ciaraldi, Alice Kong, Dennis Kim, Neelima Chu, Pharis Mohideen, Sunder Mudaliar, Robert R. Henry, Barbara B. Kahn
Journal: Diabetes
Diabetes 2002;51(2):443–448
https://doi.org/10.2337/diabetes.51.2.443
Published: 01 February 2002
View article titled, Troglitazone but not Metformin Restores Insulin-Stimulated Phosphoinositide 3-Kinase Activity and Increases p110β Protein Levels in Skeletal Muscle of Type 2 Diabetic Subjects
Open the PDF for Troglitazone but not Metformin Restores Insulin-Stimulated Phosphoinositide 3-Kinase Activity and Increases p110β Protein Levels in Skeletal Muscle of Type 2 Diabetic Subjects in another window