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Yuji Matsuzawa
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Journal Articles

Adiponectin, Change in Adiponectin, and Progression to Diabetes in the Diabetes Prevention Program

Kieren J. Mather, Tohru Funahashi, Yuji Matsuzawa, Sharon Edelstein, George A. Bray, Steven E. Kahn, Jill Crandall, Santica Marcovina, Barry Goldstein, Ronald Goldberg, for the Diabetes Prevention Program
Journal: Diabetes
Diabetes 2008;57(4):980–986
https://doi.org/10.2337/db07-1419
Published: 01 April 2008
View article titled, Adiponectin, Change in Adiponectin, and Progression to Diabetes in the Diabetes Prevention Program
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Includes: Supplementary data
Journal Articles

Common Polymorphisms in the Adiponectin Gene ACDC Are Not Associated With Diabetes in Pima Indians

Barbora Vozarova de Courten, Robert L. Hanson, Tohru Funahashi, Robert S. Lindsay, Yuji Matsuzawa, Sachiyo Tanaka, Farook Thameem, Jonathan D. Gruber, Philippe Froguel, Johanna K. Wolford
Journal: Diabetes
Diabetes 2005;54(1):284–289
https://doi.org/10.2337/diabetes.54.1.284
Published: 01 January 2005
View article titled, Common Polymorphisms in the Adiponectin Gene <em>ACDC</em> Are Not Associated With Diabetes in Pima Indians
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Journal Articles

Peripheral, But Not Central, Administration of Adiponectin Reduces Visceral Adiposity and Upregulates the Expression of Uncoupling Protein in Agouti Yellow (Ay/a) Obese Mice

Takayuki Masaki, Seiichi Chiba, Tohru Yasuda, Tetsuo Tsubone, Tetsuya Kakuma, Iichiro Shimomura, Tohru Funahashi, Yuji Matsuzawa, Hironobu Yoshimatsu
Journal: Diabetes
Diabetes 2003;52(9):2266–2273
https://doi.org/10.2337/diabetes.52.9.2266
Published: 01 September 2003
View article titled, Peripheral, But Not Central, Administration of Adiponectin Reduces Visceral Adiposity and Upregulates the Expression of Uncoupling Protein in Agouti Yellow (<em>A<sup>y</sup>/a</em>) Obese Mice
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Journal Articles

Genome-Wide Linkage Analysis of Serum Adiponectin in the Pima Indian Population

Robert S. Lindsay, Tohru Funahashi, Jonathan Krakoff, Yuji Matsuzawa, Sachiyo Tanaka, Sayuko Kobes, Peter H. Bennett, P. Antonio Tataranni, William C. Knowler, Robert L. Hanson
Journal: Diabetes
Diabetes 2003;52(9):2419–2425
https://doi.org/10.2337/diabetes.52.9.2419
Published: 01 September 2003
View article titled, Genome-Wide Linkage Analysis of Serum Adiponectin in the Pima Indian Population
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Journal Articles

Induction of Adiponectin, a Fat-Derived Antidiabetic and Antiatherogenic Factor, by Nuclear Receptors

Masanori Iwaki, Morihiro Matsuda, Norikazu Maeda, Tohru Funahashi, Yuji Matsuzawa, Makoto Makishima, Iichiro Shimomura
Journal: Diabetes
Diabetes 2003;52(7):1655–1663
https://doi.org/10.2337/diabetes.52.7.1655
Published: 01 July 2003
View article titled, Induction of Adiponectin, a Fat-Derived Antidiabetic and Antiatherogenic Factor, by Nuclear Receptors
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Journal Articles

Overexpression of PACAP in Transgenic Mouse Pancreatic β-Cells Enhances Insulin Secretion and Ameliorates Streptozotocin-induced Diabetes

Kyohei Yamamoto, Hitoshi Hashimoto, Shuhei Tomimoto, Norihito Shintani, Jun-ichi Miyazaki, Fumi Tashiro, Hiroyuki Aihara, Takao Nammo, Ming Li, Kazuya Yamagata, Jun-ichiro Miyagawa, Yuji Matsuzawa, Yuki Kawabata, Yuji Fukuyama, Kazumi Koga, Wakaba Mori, Kazuhiro Tanaka, Toshio Matsuda, Akemichi Baba
Journal: Diabetes
Diabetes 2003;52(5):1155–1162
https://doi.org/10.2337/diabetes.52.5.1155
Published: 01 May 2003
View article titled, Overexpression of PACAP in Transgenic Mouse Pancreatic β-Cells Enhances Insulin Secretion and Ameliorates Streptozotocin-induced Diabetes
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Journal Articles

Low Plasma Adiponectin Concentrations Do Not Predict Weight Gain in Humans

Barbora Vozarova, Norbert Stefan, Robert S. Lindsay, Jonathan Krakoff, William C. Knowler, Tohru Funahashi, Yuji Matsuzawa, Michael Stumvoll, Christian Weyer, P. Antonio Tataranni
Journal: Diabetes
Diabetes 2002;51(10):2964–2967
https://doi.org/10.2337/diabetes.51.10.2964
Published: 01 October 2002
View article titled, Low Plasma Adiponectin Concentrations Do Not Predict Weight Gain in Humans
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Journal Articles

Coordinated Regulation of Fat-Specific and Liver-Specific Glycerol Channels, Aquaporin Adipose and Aquaporin 9

Hiroshi Kuriyama, Iichiro Shimomura, Ken Kishida, Hidehiko Kondo, Naoki Furuyama, Hitoshi Nishizawa, Norikazu Maeda, Morihiro Matsuda, Hiroyuki Nagaretani, Shinji Kihara, Tadashi Nakamura, Yoshihiro Tochino, Tohru Funahashi, Yuji Matsuzawa
Journal: Diabetes
Diabetes 2002;51(10):2915–2921
https://doi.org/10.2337/diabetes.51.10.2915
Published: 01 October 2002
View article titled, Coordinated Regulation of Fat-Specific and Liver-Specific Glycerol Channels, Aquaporin Adipose and Aquaporin 9
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Journal Articles

Androgens Decrease Plasma Adiponectin, an Insulin-Sensitizing Adipocyte-Derived Protein

Hitoshi Nishizawa, Iichiro Shimomura, Ken Kishida, Norikazu Maeda, Hiroshi Kuriyama, Hiroyuki Nagaretani, Morihiro Matsuda, Hidehiko Kondo, Naoki Furuyama, Shinji Kihara, Tadashi Nakamura, Yoshihiro Tochino, Tohru Funahashi, Yuji Matsuzawa
Journal: Diabetes
Diabetes 2002;51(9):2734–2741
https://doi.org/10.2337/diabetes.51.9.2734
Published: 01 September 2002
View article titled, Androgens Decrease Plasma Adiponectin, an Insulin-Sensitizing Adipocyte-Derived Protein
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Journal Articles

Association of Adiponectin Mutation With Type 2 Diabetes : A Candidate Gene for the Insulin Resistance Syndrome

Hidehiko Kondo, Iichiro Shimomura, Yuko Matsukawa, Masahiro Kumada, Masahiko Takahashi, Morihiro Matsuda, Noriyuki Ouchi, Shinji Kihara, Toshiharu Kawamoto, Satoru Sumitsuji, Tohru Funahashi, Yuji Matsuzawa
Journal: Diabetes
Diabetes 2002;51(7):2325–2328
https://doi.org/10.2337/diabetes.51.7.2325
Published: 01 July 2002
View article titled, Association of Adiponectin Mutation With Type 2 Diabetes : <subtitle>A Candidate Gene for the Insulin Resistance Syndrome </subtitle>
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Journal Articles

Hepatocyte Nuclear Factor-1α Modulates Pancreatic β-Cell Growth by Regulating the Expression of Insulin-Like Growth Factor-1 in INS-1 Cells

Qin Yang, Kazuya Yamagata, Kenji Fukui, Yang Cao, Takao Nammo, Hiromi Iwahashi, Haiyan Wang, Itaru Matsumura, Toshiaki Hanafusa, Richard Bucala, Claes B. Wollheim, Jun-ichiro Miyagawa, Yuji Matsuzawa
Journal: Diabetes
Diabetes 2002;51(6):1785–1792
https://doi.org/10.2337/diabetes.51.6.1785
Published: 01 June 2002
View article titled, Hepatocyte Nuclear Factor-1α Modulates Pancreatic β-Cell Growth by Regulating the Expression of Insulin-Like Growth Factor-1 in INS-1 Cells
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Journal Articles

Plasma Adiponectin Concentration Is Associated With Skeletal Muscle Insulin Receptor Tyrosine Phosphorylation, and Low Plasma Concentration Precedes a Decrease in Whole-Body Insulin Sensitivity in Humans

Norbert Stefan, Barbora Vozarova, Tohru Funahashi, Yuji Matsuzawa, Christian Weyer, Robert S. Lindsay, Jack F. Youngren, Peter J. Havel, Richard E. Pratley, Clifton Bogardus, P. Antonio Tataranni
Journal: Diabetes
Diabetes 2002;51(6):1884–1888
https://doi.org/10.2337/diabetes.51.6.1884
Published: 01 June 2002
View article titled, Plasma Adiponectin Concentration Is Associated With Skeletal Muscle Insulin Receptor Tyrosine Phosphorylation, and Low Plasma Concentration Precedes a Decrease in Whole-Body Insulin Sensitivity in Humans
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Journal Articles

Thyroid Hormone Receptor Interacting Protein 3 (Trip3) Is a Novel Coactivator of Hepatocyte Nuclear Factor-4α

Hiromi Iwahashi, Kazuya Yamagata, Issei Yoshiuchi, Jungo Terasaki, Qin Yang, Kenji Fukui, Arisa Ihara, Qian Zhu, Takeshi Asakura, Yang Cao, Akihisa Imagawa, Mitsuyoshi Namba, Toshiaki Hanafusa, Jun-ichiro Miyagawa, Yuji Matsuzawa
Journal: Diabetes
Diabetes 2002;51(4):910–914
https://doi.org/10.2337/diabetes.51.4.910
Published: 01 April 2002
View article titled, Thyroid Hormone Receptor Interacting Protein 3 (Trip3) Is a Novel Coactivator of Hepatocyte Nuclear Factor-4α
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Journal Articles

Overexpression of Dominant-Negative Mutant Hepatocyte Nuclear Factor-1α in Pancreatic β-Cells Causes Abnormal Islet Architecture With Decreased Expression of E-Cadherin, Reduced β-cell Proliferation, and Diabetes

Kazuya Yamagata, Takao Nammo, Makoto Moriwaki, Arisa Ihara, Katsumi Iizuka, Qin Yang, Tomomi Satoh, Ming Li, Rikako Uenaka, Kohei Okita, Hiromi Iwahashi, Qian Zhu, Yang Cao, Akihisa Imagawa, Yoshihiro Tochino, Toshiaki Hanafusa, Jun-ichiro Miyagawa, Yuji Matsuzawa
Journal: Diabetes
Diabetes 2002;51(1):114–123
https://doi.org/10.2337/diabetes.51.1.114
Published: 01 January 2002
View article titled, Overexpression of Dominant-Negative Mutant Hepatocyte Nuclear Factor-1α in Pancreatic β-Cells Causes Abnormal Islet Architecture With Decreased Expression of E-Cadherin, Reduced β-cell Proliferation, and Diabetes
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Journal Articles

PPARγ Ligands Increase Expression and Plasma Concentrations of Adiponectin, an Adipose-Derived Protein

Norikazu Maeda, Masahiko Takahashi, Tohru Funahashi, Shinji Kihara, Hitoshi Nishizawa, Ken Kishida, Hiroyuki Nagaretani, Morihiro Matsuda, Ryutaro Komuro, Noriyuki Ouchi, Hiroshi Kuriyama, Kikuko Hotta, Tadashi Nakamura, Iichiro Shimomura, Yuji Matsuzawa
Journal: Diabetes
Diabetes 2001;50(9):2094–2099
https://doi.org/10.2337/diabetes.50.9.2094
Published: 01 September 2001
View article titled, PPARγ Ligands Increase Expression and Plasma Concentrations of Adiponectin, an Adipose-Derived Protein
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Journal Articles

Pancreatic Biopsy as a Procedure for Detecting In Situ Autoimmune Phenomena in Type 1 Diabetes: Close Correlation Between Serological Markers and Histological Evidence of Cellular Autoimmunity

Akihisa Imagawa, Toshiaki Hanafusa, Shinji Tamura, Makoto Moriwaki, Naoto Itoh, Koji Yamamoto, Hiromi Iwahashi, Kazuya Yamagata, Masako Waguri, Takao Nanmo, Sae Uno, Hiromu Nakajima, Mitsuyoshi Namba, Sumio Kawata, Jun-ichiro Miyagawa, Yuji Matsuzawa
Journal: Diabetes
Diabetes 2001;50(6):1269–1273
https://doi.org/10.2337/diabetes.50.6.1269
Published: 01 June 2001
View article titled, Pancreatic Biopsy as a Procedure for Detecting In Situ Autoimmune Phenomena in Type 1 Diabetes: <subtitle>Close Correlation Between Serological Markers and Histological Evidence of Cellular Autoimmunity</subtitle>
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Journal Articles

Circulating Concentrations of the Adipocyte Protein Adiponectin Are Decreased in Parallel With Reduced Insulin Sensitivity During the Progression to Type 2 Diabetes in Rhesus Monkeys

Kikuko Hotta, Tohru Funahashi, Noni L. Bodkin, Heidi K. Ortmeyer, Yukio Arita, Barbara C. Hansen, Yuji Matsuzawa
Journal: Diabetes
Diabetes 2001;50(5):1126–1133
https://doi.org/10.2337/diabetes.50.5.1126
Published: 01 May 2001
View article titled, Circulating Concentrations of the Adipocyte Protein Adiponectin Are Decreased in Parallel With Reduced Insulin Sensitivity During the Progression to Type 2 Diabetes in Rhesus Monkeys
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Journal Articles

Mutation P291fsinsC in the Transcription Factor Hepatocyte Nuclear Factor-1α is Dominant Negative

Kazuya Yamagata, Qin Yang, Koji Yamamoto, Hiromi Iwahashi, Jun-ichiro Miyagawa, Kohei Okita, Issei Yoshiuchi, Jun-ichi Miyazaki, Tamio Noguchi, Hiromu Nakajima, Mitsuyoshi Namba, Toshiaki Hanafusa, Yuji Matsuzawa
Journal: Diabetes
Diabetes 1998;47(8):1231–1235
https://doi.org/10.2337/diab.47.8.1231
Published: 01 August 1998
View article titled, Mutation P291fsinsC in the Transcription Factor Hepatocyte Nuclear Factor-1α is Dominant Negative
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Journal Articles

Demonstration of Two Different Processes of β-Cell Regeneration in a New Diabetic Mouse Model Induced by Selective Perfusion of Alloxan

Masako Waguri, Koji Yamamoto, Jun-ichiro Miyagawa, Yoshihiro Tochino, Katsumi Yamamori, Yoshitaka Kajimoto, Hiromu Nakajima, Hirotaka Watada, Issei Yoshiuchi, Naoto Itoh, Akihisa Imagawa, Mitsuyoshi Namba, Masamichi Kuwajima, Yoshimitsu Yamasaki, Toshiaki Hanafusa, Yuji Matsuzawa
Journal: Diabetes
Diabetes 1997;46(8):1281–1290
https://doi.org/10.2337/diab.46.8.1281
Published: 01 August 1997
View article titled, Demonstration of Two Different Processes of β-Cell Regeneration in a New Diabetic Mouse Model Induced by Selective Perfusion of Alloxan
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Journal Articles

PDX-1 Induces Insulin and Glucokinase Gene Expressions in αTC1 Clone 6 Cells in the Presence of Betacellulin

Hirotaka Watada, Yoshitaka Kajimoto, Jun-ichiro Miyagawa, Toshiaki Hanafusa, Kazuyuki Hamaguchi, Taka-aki Matsuoka, Koji Yamamoto, Yuji Matsuzawa, Ryuzo Kawamori, Yoshimitsu Yamasaki
Journal: Diabetes
Diabetes 1996;45(12):1826–1831
https://doi.org/10.2337/diab.45.12.1826
Published: 01 December 1996
View article titled, PDX-1 Induces Insulin and Glucokinase Gene Expressions in αTC1 Clone 6 Cells in the Presence of Betacellulin
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