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Journal Articles

Glucagon Stimulation Test and Insulin Secretory Capacity in the Clinical Assessment of Incretin-Based Therapy for Diabetes

Takuya Haraguchi, Yuji Yamazaki, Hitoshi Kuwata, Ryota Usui, Yoshiyuki Hamamoto, Yutaka Seino, Daisuke Yabe, Yuichiro Yamada

Diabetes 2024;73(12):2078–2083

https://doi.org/10.2337/db24-0518

Published: 28 August 2024

View article titled, Glucagon Stimulation Test and Insulin Secretory Capacity in the Clinical Assessment of Incretin-Based Therapy for Diabetes

Meeting Abstracts

1888-LB: Differential Effect of Imeglimin Compared with Metformin on Insulin and Incretin Secretion—A Randomized Controlled Trial

RYOTA USUI, YOSHIYUKI HAMAMOTO, MASAHIRO IMURA, YASUHIRO OMORI, YURI KUROTOBI, HITOSHI KUWATA, HISATO TATSUOKA, KAZUHIRO SHIMOMURA, KENTA MUROTANI, YUICHIRO YAMADA, YUTAKA SEINO

Diabetes 2024;73(Supplement_1):1888-LB

https://doi.org/10.2337/db24-1888-LB

Published: 14 June 2024

View article titled, 1888-LB: Differential Effect of Imeglimin Compared with Metformin on Insulin and Incretin Secretion—A Randomized Controlled Trial

Meeting Abstracts

878-P: Absolute Amount of Urinary Glucose Excretion, Not the Change, Is the Measure Determinant for the Effects of SGLT2 inhibitors

YOSHIYUKI HAMAMOTO, YUICHIRO YAMADA, YUTAKA SEINO

Diabetes 2023;72(Supplement_1):878-P

https://doi.org/10.2337/db23-878-P

Published: 20 June 2023

View article titled, 878-P: Absolute Amount of Urinary Glucose Excretion, Not the Change, Is the Measure Determinant for the Effects of SGLT2 inhibitors

Meeting Abstracts

1658-P: A Novel Mutation in Hepatocyte Nuclear Factor-1 Beta (HNF1B) in Maturity-Onset Diabetes of the Young 5 (MODY5)

YUKI FUJITA, TAKANORI HYO, MIHO MATSUBARA, YOSHIYUKI HAMAMOTO, DAISUKE TANAKA, YUTAKA SEINO

Diabetes 2020;69(Supplement_1):1658-P

https://doi.org/10.2337/db20-1658-P

Published: 01 June 2020

View article titled, 1658-P: A Novel Mutation in Hepatocyte Nuclear Factor-1 Beta (HNF1B) in Maturity-Onset Diabetes of the Young 5 (MODY5)

Meeting Abstracts

926-P: Cardiovascular (CV) and Hypoglycemia Outcomes across Age Groups in People with Type 2 Diabetes (T2D) in the CAROLINA Trial

MARK ESPELAND, RICHARD E. PRATLEY, JULIO ROSENSTOCK, TAKASHI KADOWAKI, YUTAKA SEINO, BERNARD ZINMAN, NIKOLAUS MARX, DARREN K. MCGUIRE, KNUT R. ANDERSEN, MICHAELA MATTHEUS, ANNETT KELLER, ODD ERIK JOHANSEN

Diabetes 2020;69(Supplement_1):926-P

https://doi.org/10.2337/db20-926-P

Published: 01 June 2020

View article titled, 926-P: Cardiovascular (CV) and Hypoglycemia Outcomes across Age Groups in People with Type 2 Diabetes (T2D) in the CAROLINA Trial

Meeting Abstracts

786-P: Serum Dehydroepiandrosterone Sulfate Concentration and Animal Protein Intakes Are Important Factors for Skeletal Muscle Mass in Japanese Patients with Type 2 Diabetes

SHOTA MOYAMA, HITOSHI KUWATA, YOSHIYUKI HAMAMOTO, DAISUKE YABE, YUTAKA SEINO

Diabetes 2019;68(Supplement_1):786-P

https://doi.org/10.2337/db19-786-P

Published: 01 June 2019

View article titled, 786-P: Serum Dehydroepiandrosterone Sulfate Concentration and Animal Protein Intakes Are Important Factors for Skeletal Muscle Mass in Japanese Patients with Type 2 Diabetes

Meeting Abstracts

771-P: Protein Intake at Breakfast Contributes to Maintenance of Skeletal Muscle Mass in Japanese Elderly Patients with Type 2 Diabetes

SODAI KUBOTA, HITOSHI KUWATA, SAKI OKAMOTO, DAISUKE YABE, KENTA MUROTANI, YOSHIYUKI HAMAMOTO, YUTAKA SEINO

Diabetes 2019;68(Supplement_1):771-P

https://doi.org/10.2337/db19-771-P

Published: 01 June 2019

View article titled, 771-P: Protein Intake at Breakfast Contributes to Maintenance of Skeletal Muscle Mass in Japanese Elderly Patients with Type 2 Diabetes

Meeting Abstracts

1018-P: Comparison of Short- and Long-Acting Glucagon-Like Peptide-1 Receptor Agonist Effects on Postprandial Glucose and Lipid Excursion via Gastric Emptying

HITOSHI KUWATA, DAISUKE YABE, YOSHIYUKI HAMAMOTO, TAKESHI KUROSE, YUTAKA SEINO

Diabetes 2019;68(Supplement_1):1018-P

https://doi.org/10.2337/db19-1018-P

Published: 01 June 2019

View article titled, 1018-P: Comparison of Short- and Long-Acting Glucagon-Like Peptide-1 Receptor Agonist Effects on Postprandial Glucose and Lipid Excursion via Gastric Emptying

Meeting Abstracts

1019-P: Glucagon-Like Peptide-1 Receptor Agonists Predominantly Reduce Body Fat Mass in Patients with Type 2 Diabetes

YUKI FUJITA, SODAI KUBOTA, HITOSHI KUWATA, DAISUKE YABE, YOSHIYUKI HAMAMOTO, YUTAKA SEINO

Diabetes 2019;68(Supplement_1):1019-P

https://doi.org/10.2337/db19-1019-P

Published: 01 June 2019

View article titled, 1019-P: Glucagon-Like Peptide-1 Receptor Agonists Predominantly Reduce Body Fat Mass in Patients with Type 2 Diabetes

Meeting Abstracts

1734-P: A Considerable Mismatch of Measurements between Radioimmunoassay and Enzyme-Linked Immunosorbent Assay Tests for Anti-Glutamic Acid Decarboxylase Antibody

YOICHI OIKAWA, TAKUMA KONDO, AKIRA SHIMADA, YUTAKA SEINO, MASAFUMI KITAOKA

Diabetes 2019;68(Supplement_1):1734-P

https://doi.org/10.2337/db19-1734-P

Published: 01 June 2019

View article titled, 1734-P: A Considerable Mismatch of Measurements between Radioimmunoassay and Enzyme-Linked Immunosorbent Assay Tests for Anti-Glutamic Acid Decarboxylase Antibody

Meeting Abstracts

Safety and Tolerability of Empagliflozin in East Asian Patients with Type 2 Diabetes—Pooled Analysis of Phase I-III Clinical Trials

ATSUTAKA YASUI, DAISUKE YABE, LINONG JI, MOON-KYU LEE, RONALD C. MA, TIEN-JYUN CHANG, TOMOO OKAMURA, CORDULA ZELLER, STEFAN KASPERS, JISOO LEE, SVEN KOHLER, YUTAKA SEINO

Diabetes 2018;67(Supplement_1):1150-P

https://doi.org/10.2337/db18-1150-P

Published: 01 July 2018

View article titled, Safety and Tolerability of Empagliflozin in East Asian Patients with Type 2 Diabetes—Pooled Analysis of Phase I-III Clinical Trials

Meeting Abstracts

Deterioration of HbA1c-Lowering Effects in Dipeptidyl-Peptidase Inhibitor and Dietary Habits in Japanese Type 2 Diabetes—Comparison with That of Metformin

SAKI OKAMOTO, HITOSHI KUWATA, DAISUKE YABE, KENTA MUROTANI, YUSUKE SEINO, RYOTA USUI, HISATO TATSUOKA, YOSHIYUKI HAMAMOTO, TAKESHI KUROSE, YUTAKA SEINO

Diabetes 2018;67(Supplement_1):2306-PUB

https://doi.org/10.2337/db18-2306-PUB

Published: 01 July 2018

View article titled, Deterioration of HbA1c-Lowering Effects in Dipeptidyl-Peptidase Inhibitor and Dietary Habits in Japanese Type 2 Diabetes—Comparison with That of Metformin

Meeting Abstracts

Factors Responsible for Progression of Microalbuminuria in Japanese Patients with Type 2 Diabetes-Retrospective Analysis

SODAI KUBOTA, HITOSHI KUWATA, DAISUKE YABE, KENTA MUROTANI, YOSHIYUKI HAMAMOTO, TAKESHI KUROSE, YUTAKA SEINO

Diabetes 2018;67(Supplement_1):540-P

https://doi.org/10.2337/db18-540-P

Published: 01 July 2018

View article titled, Factors Responsible for Progression of Microalbuminuria in Japanese Patients with Type 2 Diabetes-Retrospective Analysis

Meeting Abstracts

Effects of Dietary Instructions Including Meal-Sequence for Prediabetes Subjects—Comparison with Conventional Approach

DAISUKE YABE, HITOSHI KUWATA, YUUKA FUJIWARA, KENTA MUROTANI, SANAE ITO, HIROSHI ASANO, HIDEYUKI MISHIMA, HIDETO TAKASE, NORIYASU OOTA, YUSUKE SEINO, YOSHIYUKI HAMAMOTO, TAKESHI KUROSE, YUTAKA SEINO

Diabetes 2018;67(Supplement_1):53-LB

https://doi.org/10.2337/db18-53-LB

Published: 01 July 2018

View article titled, Effects of Dietary Instructions Including Meal-Sequence for Prediabetes Subjects—Comparison with Conventional Approach

Journal Articles

Ectopic Expression of GIP in Pancreatic β-Cells Maintains Enhanced Insulin Secretion in Mice With Complete Absence of Proglucagon-Derived Peptides

Ayako Fukami, Yusuke Seino, Nobuaki Ozaki, Michiyo Yamamoto, Chisato Sugiyama, Eriko Sakamoto-Miura, Tatsuhito Himeno, Yoshiko Takagishi, Shin Tsunekawa, Safina Ali, Daniel J. Drucker, Yoshiharu Murata, Yutaka Seino, Yutaka Oiso, Yoshitaka Hayashi

Diabetes 2013;62(2):510–518

https://doi.org/10.2337/db12-0294

Published: 17 January 2013

View article titled, Ectopic Expression of GIP in Pancreatic β-Cells Maintains Enhanced Insulin Secretion in Mice With Complete Absence of Proglucagon-Derived Peptides

Includes: Supplementary data

Journal Articles

Gipr Is Essential for Adrenocortical Steroidogenesis; However, Corticosterone Deficiency Does Not Mediate the Favorable Metabolic Phenotype of Gipr^−/− Mice

Holly E. Bates, Jonathan E. Campbell, John R. Ussher, Laurie L. Baggio, Adriano Maida, Yutaka Seino, Daniel J. Drucker

Diabetes 2012;61(1):40–48

https://doi.org/10.2337/db11-1060

Published: 12 December 2011

View article titled, Gipr Is Essential for Adrenocortical Steroidogenesis; However, Corticosterone Deficiency Does Not Mediate the Favorable Metabolic Phenotype of Gipr−/− Mice

Includes: Supplementary data

Journal Articles

Beneficial Effects of Exendin-4 on Experimental Polyneuropathy in Diabetic Mice

Tatsuhito Himeno, Hideki Kamiya, Keiko Naruse, Norio Harada, Nobuaki Ozaki, Yusuke Seino, Taiga Shibata, Masaki Kondo, Jiro Kato, Tetsuji Okawa, Ayako Fukami, Yoji Hamada, Nobuya Inagaki, Yutaka Seino, Daniel J. Drucker, Yutaka Oiso, Jiro Nakamura

Diabetes 2011;60(9):2397–2406

https://doi.org/10.2337/db10-1462

Published: 20 August 2011

View article titled, Beneficial Effects of Exendin-4 on Experimental Polyneuropathy in Diabetic Mice

Includes: Supplementary data

Journal Articles

Insulin Action in the Double Incretin Receptor Knockout Mouse

Julio E. Ayala, Deanna P. Bracy, Tanya Hansotia, Grace Flock, Yutaka Seino, David H. Wasserman, Daniel J. Drucker

Diabetes 2008;57(2):288–297

https://doi.org/10.2337/db07-0704

Published: 01 February 2008

View article titled, Insulin Action in the Double Incretin Receptor Knockout Mouse

Journal Articles

Pancreatic and Extrapancreatic Effects of Gastric Inhibitory Polypeptide

Yuichiro Yamada, Kazumasa Miyawaki, Katsushi Tsukiyama, Norio Harada, Chizumi Yamada, Yutaka Seino

Diabetes 2006;55(Supplement_2):S86–S91

https://doi.org/10.2337/db06-S011

Published: 01 December 2006

View article titled, Pancreatic and Extrapancreatic Effects of Gastric Inhibitory Polypeptide

Journal Articles

Association Studies of Variants in the Genes Involved in Pancreatic β-Cell Function in Type 2 Diabetes in Japanese Subjects

Diabetes 2006;55(8):2379–2386

https://doi.org/10.2337/db05-1203

Published: 01 August 2006

View article titled, Association Studies of Variants in the Genes Involved in Pancreatic β-Cell Function in Type 2 Diabetes in Japanese Subjects

Includes: Supplementary data

NARROW

Glucagon Stimulation Test and Insulin Secretory Capacity in the Clinical Assessment of Incretin-Based Therapy for Diabetes

1888-LB: Differential Effect of Imeglimin Compared with Metformin on Insulin and Incretin Secretion—A Randomized Controlled Trial

878-P: Absolute Amount of Urinary Glucose Excretion, Not the Change, Is the Measure Determinant for the Effects of SGLT2 inhibitors

1658-P: A Novel Mutation in Hepatocyte Nuclear Factor-1 Beta (HNF1B) in Maturity-Onset Diabetes of the Young 5 (MODY5)

926-P: Cardiovascular (CV) and Hypoglycemia Outcomes across Age Groups in People with Type 2 Diabetes (T2D) in the CAROLINA Trial

786-P: Serum Dehydroepiandrosterone Sulfate Concentration and Animal Protein Intakes Are Important Factors for Skeletal Muscle Mass in Japanese Patients with Type 2 Diabetes

771-P: Protein Intake at Breakfast Contributes to Maintenance of Skeletal Muscle Mass in Japanese Elderly Patients with Type 2 Diabetes

1018-P: Comparison of Short- and Long-Acting Glucagon-Like Peptide-1 Receptor Agonist Effects on Postprandial Glucose and Lipid Excursion via Gastric Emptying

1019-P: Glucagon-Like Peptide-1 Receptor Agonists Predominantly Reduce Body Fat Mass in Patients with Type 2 Diabetes

1734-P: A Considerable Mismatch of Measurements between Radioimmunoassay and Enzyme-Linked Immunosorbent Assay Tests for Anti-Glutamic Acid Decarboxylase Antibody

Safety and Tolerability of Empagliflozin in East Asian Patients with Type 2 Diabetes—Pooled Analysis of Phase I-III Clinical Trials

Deterioration of HbA1c-Lowering Effects in Dipeptidyl-Peptidase Inhibitor and Dietary Habits in Japanese Type 2 Diabetes—Comparison with That of Metformin

Factors Responsible for Progression of Microalbuminuria in Japanese Patients with Type 2 Diabetes-Retrospective Analysis

Effects of Dietary Instructions Including Meal-Sequence for Prediabetes Subjects—Comparison with Conventional Approach

Ectopic Expression of GIP in Pancreatic β-Cells Maintains Enhanced Insulin Secretion in Mice With Complete Absence of Proglucagon-Derived Peptides

Gipr Is Essential for Adrenocortical Steroidogenesis; However, Corticosterone Deficiency Does Not Mediate the Favorable Metabolic Phenotype of Gipr^−/− Mice

Beneficial Effects of Exendin-4 on Experimental Polyneuropathy in Diabetic Mice

Insulin Action in the Double Incretin Receptor Knockout Mouse

Pancreatic and Extrapancreatic Effects of Gastric Inhibitory Polypeptide

Association Studies of Variants in the Genes Involved in Pancreatic β-Cell Function in Type 2 Diabetes in Japanese Subjects

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