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Journal Articles

Acceptance of Murine Islet Allografts Without Immunosuppression in Inguinal Subcutaneous White Adipose Tissue Pretreated With bFGF

Yuki Nakafusa, Naoyoshi Nitta, Kazunari Ishii, Naoto Shirasu, Takahiro Iwamoto, Takayuki Nemoto, Masafumi Nakamura, Masafumi Goto, Hiroo Iwata, Masaru Taniguchi, Yohichi Yasunami
Journal: Diabetes
Diabetes 2022;71(8):1721–1734
https://doi.org/10.2337/db21-0684
Published: 21 August 2022
View article titled, Acceptance of Murine Islet Allografts Without Immunosuppression in Inguinal Subcutaneous White Adipose Tissue Pretreated With bFGF
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Journal Articles

Localized Immunosuppression With Tannic Acid Encapsulation Delays Islet Allograft and Autoimmune-Mediated Rejection

Jessie M. Barra, Veronika Kozlovskaya, Eugenia Kharlampieva, Hubert M. Tse
Journal: Diabetes
Diabetes 2020;69(9):1948–1960
https://doi.org/10.2337/db20-0248
Published: 25 June 2020
View article titled, Localized Immunosuppression With Tannic Acid Encapsulation Delays Islet Allograft and Autoimmune-Mediated Rejection
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Journal Articles

Low-Dose Interleukin-2 Combined With Rapamycin Led to an Expansion of CD4+CD25+FOXP3+ Regulatory T Cells and Prolonged Human Islet Allograft Survival in Humanized Mice

Min Hu, Wayne J. Hawthorne, Leigh Nicholson, Heather Burns, Yi Wen Qian, David Liuwantara, Elvira Jimenez Vera, Yi Vee Chew, Lindy Williams, Shounan Yi, Karen Keung, Debbie Watson, Natasha Rogers, Stephen I. Alexander, Philip J. O’Connell
Journal: Diabetes
Diabetes 2020;69(8):1735–1748
https://doi.org/10.2337/db19-0525
Published: 07 May 2020
View article titled, Low-Dose Interleukin-2 Combined With Rapamycin Led to an Expansion of CD4<sup>+</sup>CD25<sup>+</sup>FOXP3<sup>+</sup> Regulatory T Cells and Prolonged Human Islet Allograft Survival in Humanized Mice
Open the PDF for Low-Dose Interleukin-2 Combined With Rapamycin Led to an Expansion of CD4<sup>+</sup>CD25<sup>+</sup>FOXP3<sup>+</sup> Regulatory T Cells and Prolonged Human Islet Allograft Survival in Humanized Mice in another window
Meeting Abstracts

218-OR: Does the Reparixin (CXCR1/2 Inhibitor) Improve Islet Cell Engraftment and Clinical Outcomes after Pancreatic Islet Allotransplantation in Patients with Type 1 Diabetes Mellitus? A Randomized, Double-Blind, Prospective Study

PIOTR J. BACHUL, JUSTYNA E. GOLEBIEWSKA, MONICA PARA, FILIP ANTIC, LINDSAY BASTO, LAURENCIA PEREA, KAROLINA GOLAB, LING-JIA WANG, MARTIN L. TIBUDAN, CELESTE C. THOMAS, PIOTR WITKOWSK
Journal: Diabetes
Diabetes 2019;68(Supplement_1):218-OR
https://doi.org/10.2337/db19-218-OR
Published: 01 June 2019
View article titled, 218-OR: Does the Reparixin (CXCR1/2 Inhibitor) Improve Islet Cell Engraftment and Clinical Outcomes after Pancreatic Islet Allotransplantation in Patients with Type 1 Diabetes Mellitus? A Randomized, Double-Blind, Prospective Study
Meeting Abstracts

222-OR: BETA-2 Calculated Based on Single Fasting Blood Sample Allows to Define and Discriminate between Optimal and Suboptimal Islet Allograft Function Prior to the Clinical Need for Insulin Support

PIOTR J. BACHUL, JUSTYNA E. GOLEBIEWSKA, FILIP ANTIC, MONICA PARA, LINDSAY BASTO, KAROLINA GOLAB, LAURENCIA PEREA, LING-JIA WANG, MARTIN L. TIBUDAN, CELESTE C. THOMAS, PIOTR WITKOWSKI
Journal: Diabetes
Diabetes 2019;68(Supplement_1):222-OR
https://doi.org/10.2337/db19-222-OR
Published: 01 June 2019
View article titled, 222-OR: BETA-2 Calculated Based on Single Fasting Blood Sample Allows to Define and Discriminate between Optimal and Suboptimal Islet Allograft Function Prior to the Clinical Need for Insulin Support
Meeting Abstracts

Acceptance of Murine Islet Allografts without Immunosuppression in the Inguinal Subcutaneous White Adipose Tissue Pretreated with bFGF

YUKI NAKAFUSA, NAOYOSHI NITTA, MASAFUNI NAKAMURA, YOHICHI YASUNAMI
Journal: Diabetes
Diabetes 2018;67(Supplement_1):32-OR
https://doi.org/10.2337/db18-32-OR
Published: 01 July 2018
View article titled, Acceptance of Murine Islet Allografts without Immunosuppression in the Inguinal Subcutaneous White Adipose Tissue Pretreated with bFGF
Meeting Abstracts

Prolongation of Allograft Survival by Intrathymic Introduction of Allogeneic Thymic Epithelial Cells

ISHA PRADHAN, STEPHANIE WONG-NOONAN, SUZANNE BERTERA, ROBERT J. LAKOMY, HENRY COHEN, DERRICK WELLS, MASSIMO TRUCCO, YONG FAN
Journal: Diabetes
Diabetes 2018;67(Supplement_1):30-OR
https://doi.org/10.2337/db18-30-OR
Published: 01 July 2018
View article titled, Prolongation of Allograft Survival by Intrathymic Introduction of Allogeneic Thymic Epithelial Cells
Meeting Abstracts

Persistence of Allosensitization after Islet Allograft Failure

PAOLA RIOS, DAVID BAIDAL, NATHALIA PADILLA, ANA M. ALVAREZ GIL, SRIGITA MADIRAJU, JONATHAN AMBUT, ALEJANDRO M. MANTERO, CAMILLO RICORDI, RODOLFO ALEJANDRO
Journal: Diabetes
Diabetes 2018;67(Supplement_1):142-OR
https://doi.org/10.2337/db18-142-OR
Published: 01 July 2018
View article titled, Persistence of Allosensitization after Islet Allograft Failure
Meeting Abstracts

Long-Term Function of Islet Allografts Transplanted on the Omentum Using a Biological Scaffold

DAVID BAIDAL, CAMILLO RICORDI, DORA M. BERMAN, ANTONELLO PILEGGI, ANA M. ALVAREZ GIL, NATHALIA PADILLA, GAETANO CIANCIO, ELINA LINETSKY, RODOLFO ALEJANDRO
Journal: Diabetes
Diabetes 2018;67(Supplement_1):140-OR
https://doi.org/10.2337/db18-140-OR
Published: 01 July 2018
View article titled, Long-Term Function of Islet Allografts Transplanted on the Omentum Using a Biological Scaffold
Journal Articles

Differential Impact of Chronic Hyperglycemia on Humoral Versus Cellular Primary Alloimmunity

Nicholas H. Bishop, Michelle K. Nelsen, K. Scott Beard, Marilyne Coulombe, Ronald G. Gill
Journal: Diabetes
Diabetes 2017;66(4):981–986
https://doi.org/10.2337/db16-0218
Published: 09 January 2017
View article titled, Differential Impact of Chronic Hyperglycemia on Humoral Versus Cellular Primary Alloimmunity
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Includes: Supplementary data
Journal Articles

Hematopoietic Stem Cell Mobilization Is Necessary but Not Sufficient for Tolerance in Islet Transplantation

Blair T. Stocks, Analise B. Thomas, Sydney K. Elizer, Yuantee Zhu, Andrew F. Marshall, Christopher S. Wilson, Daniel J. Moore
Journal: Diabetes
Diabetes 2017;66(1):127–133
https://doi.org/10.2337/db16-0444
Published: 26 October 2016
View article titled, Hematopoietic Stem Cell Mobilization Is Necessary but Not Sufficient for Tolerance in Islet Transplantation
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Includes: Supplementary data
Journal Articles

Biopatterned CTLA4/Fc Matrices Facilitate Local Immunomodulation, Engraftment, and Glucose Homeostasis After Pancreatic Islet Transplantation

Wensheng Zhang, Vijay S. Gorantla, Phil G. Campbell, Yang Li, Yang Yang, Chiaki Komatsu, Lee E. Weiss, Xin Xiao Zheng, Mario G. Solari
Journal: Diabetes
Diabetes 2016;65(12):3660–3666
https://doi.org/10.2337/db16-0320
Published: 20 September 2016
View article titled, Biopatterned CTLA4/Fc Matrices Facilitate Local Immunomodulation, Engraftment, and Glucose Homeostasis After Pancreatic Islet Transplantation
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Journal Articles

Effect of the Purinergic Inhibitor Oxidized ATP in a Model of Islet Allograft Rejection

Andrea Vergani, Carmen Fotino, Francesca D’Addio, Sara Tezza, Michele Podetta, Francesca Gatti, Melissa Chin, Roberto Bassi, Ruth D. Molano, Domenico Corradi, Rita Gatti, Maria E. Ferrero, Antonio Secchi, Fabio Grassi, Camillo Ricordi, Mohamed H. Sayegh, Paola Maffi, Antonello Pileggi, Paolo Fiorina
Journal: Diabetes
Diabetes 2013;62(5):1665–1675
https://doi.org/10.2337/db12-0242
Published: 16 April 2013
View article titled, Effect of the Purinergic Inhibitor Oxidized ATP in a Model of Islet Allograft Rejection
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Journal Articles

Human Immune System Development and Rejection of Human Islet Allografts in Spontaneously Diabetic NOD-Rag1null IL2rγnull Ins2Akita Mice

Michael A. Brehm, Rita Bortell, Philip diIorio, Jean Leif, Joseph Laning, Amy Cuthbert, Chaoxing Yang, Mary Herlihy, Lisa Burzenski, Bruce Gott, Oded Foreman, Alvin C. Powers, Dale L. Greiner, Leonard D. Shultz
Journal: Diabetes
Diabetes 2010;59(9):2265–2270
https://doi.org/10.2337/db10-0323
Published: 22 June 2010
View article titled, Human Immune System Development and Rejection of Human Islet Allografts in Spontaneously Diabetic NOD-<em>Rag1<sup>null</sup> IL2r</em>γ<sup><em>null</em></sup> <em>Ins2<sup>Akita</sup></em> Mice
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Includes: Supplementary data
Journal Articles

Local Expression of Indoleamine 2,3 Dioxygenase in Syngeneic Fibroblasts Significantly Prolongs Survival of an Engineered Three-Dimensional Islet Allograft

Reza B. Jalili, Farshad Forouzandeh, Alireza Moeen Rezakhanlou, Ryan Hartwell, Abelardo Medina, Garth L. Warnock, Bagher Larijani, Aziz Ghahary
Journal: Diabetes
Diabetes 2010;59(9):2219–2227
https://doi.org/10.2337/db09-1560
Published: 03 June 2010
View article titled, Local Expression of Indoleamine 2,3 Dioxygenase in Syngeneic Fibroblasts Significantly Prolongs Survival of an Engineered Three-Dimensional Islet Allograft
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Includes: Supplementary data
Journal Articles

Caspase Inhibitor Therapy Synergizes With Costimulation Blockade to Promote Indefinite Islet Allograft Survival

Juliet A. Emamaullee, Joy Davis, Rena Pawlick, Christian Toso, Shaheed Merani, Sui-Xiong Cai, Ben Tseng, A.M. James Shapiro
Journal: Diabetes
Diabetes 2010;59(6):1469–1477
https://doi.org/10.2337/db09-0502
Published: 23 March 2010
View article titled, Caspase Inhibitor Therapy Synergizes With Costimulation Blockade to Promote Indefinite Islet Allograft Survival
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Journal Articles

Current Advances and Travails in Islet Transplantation

David M. Harlan, Norma Sue Kenyon, Olle Korsgren, Bart O. Roep, for the Immunology of Diabetes Society
Journal: Diabetes
Diabetes 2009;58(10):2175–2184
https://doi.org/10.2337/db09-0476
Published: 01 October 2009
View article titled, Current Advances and Travails in Islet Transplantation
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Journal Articles

Pretransplant Immune Parameters Associate With Islet Allograft Outcome: Implications for Transplant Strategy?

Norma S. Kenyon, Camillo Ricordi
Journal: Diabetes
Diabetes 2009;58(10):2187–2188
https://doi.org/10.2337/db09-1147
Published: 01 October 2009
View article titled, Pretransplant Immune Parameters Associate With Islet Allograft Outcome: <subtitle>Implications for Transplant Strategy?</subtitle>
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Journal Articles

Idd Loci Synergize to Prolong Islet Allograft Survival Induced by Costimulation Blockade in NOD Mice

Julie Mangada, Todd Pearson, Michael A. Brehm, Linda S. Wicker, Laurence B. Peterson, Leonard D. Shultz, David V. Serreze, Aldo A. Rossini, Dale L. Greiner
Journal: Diabetes
Diabetes 2009;58(1):165–173
https://doi.org/10.2337/db08-0275
Published: 01 January 2009
View article titled, <em>Idd</em> Loci Synergize to Prolong Islet Allograft Survival Induced by Costimulation Blockade in NOD Mice
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Journal Articles

A Polymorphism in the Zinc Transporter Gene SLC30A8 Confers Resistance Against Posttransplantation Diabetes Mellitus in Renal Allograft Recipients

Eun Seok Kang, Myoung Soo Kim, Yu Seun Kim, Chul Hoon Kim, Seung Jin Han, Sung Wan Chun, Kyu Yeon Hur, Chung Mo Nam, Chul Woo Ahn, Bong Soo Cha, Soon Il Kim, Hyun Chul Lee
Journal: Diabetes
Diabetes 2008;57(4):1043–1047
https://doi.org/10.2337/db07-0761
Published: 01 April 2008
View article titled, A Polymorphism in the Zinc Transporter Gene <em>SLC30A8</em> Confers Resistance Against Posttransplantation Diabetes Mellitus in Renal Allograft Recipients
Open the PDF for A Polymorphism in the Zinc Transporter Gene <em>SLC30A8</em> Confers Resistance Against Posttransplantation Diabetes Mellitus in Renal Allograft Recipients in another window
Includes: Supplementary data