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Meeting Abstracts

1748-P: Brucine Topical Administration Promotes Wound Healing through Downregulation of Proinflammatory Markers and Chemokine Expressions in Alloxan-Induced Diabetic Mice

HASSAN MADKHALI, MAJID GANAIE, MOHD N. ANSARI

Diabetes 2019;68(Supplement_1):1748-P

https://doi.org/10.2337/db19-1748-P

Published: 01 June 2019

View article titled, 1748-P: Brucine Topical Administration Promotes Wound Healing through Downregulation of Proinflammatory Markers and Chemokine Expressions in Alloxan-Induced Diabetic Mice

Journal Articles

Interleukin-6 Reduces β-Cell Oxidative Stress by Linking Autophagy With the Antioxidant Response

Michelle R. Marasco, Abass M. Conteh, Christopher A. Reissaus, John E. Cupit, V, Evan M. Appleman, Raghavendra G. Mirmira, Amelia K. Linnemann

Diabetes 2018;67(8):1576–1588

https://doi.org/10.2337/db17-1280

Published: 21 May 2018

View article titled, Interleukin-6 Reduces β-Cell Oxidative Stress by Linking Autophagy With the Antioxidant Response

Includes: Supplementary data

Journal Articles

Long-term Hyperglycemia Naturally Induces Dental Caries but Not Periodontal Disease in Type 1 and Type 2 Diabetic Rodents

Yutaka Nakahara, Kiyokazu Ozaki, Tetsuro Matsuura

Diabetes 2017;66(11):2868–2874

https://doi.org/10.2337/db17-0291

Published: 09 August 2017

View article titled, Long-term Hyperglycemia Naturally Induces Dental Caries but Not Periodontal Disease in Type 1 and Type 2 Diabetic Rodents

Includes: Supplementary data

Journal Articles

¹¹¹In-exendin Uptake in the Pancreas Correlates With the β-Cell Mass and Not With the α-Cell Mass

Maarten Brom, Lieke Joosten, Cathelijne Frielink, Otto Boerman, Martin Gotthardt

Diabetes 2015;64(4):1324–1328

https://doi.org/10.2337/db14-1212

Published: 19 November 2014

View article titled, 111In-exendin Uptake in the Pancreas Correlates With the β-Cell Mass and Not With the α-Cell Mass

Journal Articles

Ventromedial Hypothalamic Glucokinase Is an Important Mediator of the Counterregulatory Response to Insulin-Induced Hypoglycemia

Barry E. Levin, Thomas C. Becker, Jun-ichi Eiki, Bei B. Zhang, Ambrose A. Dunn-Meynell

Diabetes 2008;57(5):1371–1379

https://doi.org/10.2337/db07-1755

Published: 01 May 2008

View article titled, Ventromedial Hypothalamic Glucokinase Is an Important Mediator of the Counterregulatory Response to Insulin-Induced Hypoglycemia

Journal Articles

Deletion of STAT-1 Pancreatic Islets Protects Against Streptozotocin-Induced Diabetes and Early Graft Failure but Not Against Late Rejection

Hanne I. Callewaert, Conny A. Gysemans, Laurence Ladrière, Wannes D'Hertog, Julianna Hagenbrock, Lutgart Overbergh, Decio L. Eizirik, Chantal Mathieu

Diabetes 2007;56(8):2169–2173

https://doi.org/10.2337/db07-0052

Published: 01 August 2007

View article titled, Deletion of STAT-1 Pancreatic Islets Protects Against Streptozotocin-Induced Diabetes and Early Graft Failure but Not Against Late Rejection

Includes: Supplementary data

Journal Articles

Vascular Reactivity in Arterioles From Normal and Alloxan-Diabetic Mice: Studies on Single Perfused Islets

En Yin Lai, Leif Jansson, Andreas Patzak, A. Erik G. Persson

Diabetes 2007;56(1):107–112

https://doi.org/10.2337/db06-0623

Published: 01 January 2007

View article titled, Vascular Reactivity in Arterioles From Normal and Alloxan-Diabetic Mice: <subtitle>Studies on Single Perfused Islets</subtitle>

Journal Articles

Postprandial Suppression of Glucagon Secretion Depends on Intact Pulsatile Insulin Secretion: Further Evidence for the Intraislet Insulin Hypothesis

Juris J. Meier, Lise L. Kjems, Johannes D. Veldhuis, Pierre Lefèbvre, Peter C. Butler

Diabetes 2006;55(4):1051–1056

https://doi.org/10.2337/diabetes.55.04.06.db05-1449

Published: 01 April 2006

View article titled, Postprandial Suppression of Glucagon Secretion Depends on Intact Pulsatile Insulin Secretion: <subtitle>Further Evidence for the Intraislet Insulin Hypothesis </subtitle>

Journal Articles

Failure of Transplanted Bone Marrow Cells to Adopt a Pancreatic β-Cell Fate

Jalal Taneera, Anders Rosengren, Erik Renstrom, Jens M. Nygren, Palle Serup, Patrik Rorsman, Sten Eirik W. Jacobsen

Diabetes 2006;55(2):290–296

https://doi.org/10.2337/diabetes.55.02.06.db05-1212

Published: 01 February 2006

View article titled, Failure of Transplanted Bone Marrow Cells to Adopt a Pancreatic β-Cell Fate

Journal Articles

Major Histocompatibility Complex–Linked Diabetes Susceptibility in NOD/Lt Mice : Subcongenic Analysis Localizes a Component of Idd16 at the H2-D End of the Diabetogenic H2^g7 Complex

Darcy P. Pomerleau, Rebecca J. Bagley, David V. Serreze, Clayton E. Mathews, Edward H. Leiter

Diabetes 2005;54(5):1603–1606

https://doi.org/10.2337/diabetes.54.5.1603

Published: 01 May 2005

View article titled, Major Histocompatibility Complex–Linked Diabetes Susceptibility in NOD/Lt Mice : <subtitle>Subcongenic Analysis Localizes a Component of Idd16 at the H2-D End of the Diabetogenic H2g7 Complex</subtitle>

Journal Articles

Third Ventricular Alloxan Reversibly Impairs Glucose Counterregulatory Responses

Nicole M. Sanders, Ambrose A. Dunn-Meynell, Barry E. Levin

Diabetes 2004;53(5):1230–1236

https://doi.org/10.2337/diabetes.53.5.1230

Published: 01 May 2004

View article titled, Third Ventricular Alloxan Reversibly Impairs Glucose Counterregulatory Responses

Journal Articles

ATP-Dependent K⁺ Channels Contribute to Local Metabolic Coronary Vasodilation in Experimental Diabetes

Johnathan D. Tune, Clement Yeh, Srinath Setty, H. Fred Downey

Diabetes 2002;51(4):1201–1207

https://doi.org/10.2337/diabetes.51.4.1201

Published: 01 April 2002

View article titled, ATP-Dependent K+ Channels Contribute to Local Metabolic Coronary Vasodilation in Experimental Diabetes

Journal Articles

Decrease in β-Cell Mass Leads to Impaired Pulsatile Insulin Secretion, Reduced Postprandial Hepatic Insulin Clearance, and Relative Hyperglucagonemia in the Minipig

Lise L. Kjems, Barbara M. Kirby, Elizabeth M. Welsh, Johannes D. Veldhuis, Marty Straume, Susan S. McIntyre, Dongchang Yang, Pierre Lefèbvre, Peter C. Butler

Diabetes 2001;50(9):2001–2012

https://doi.org/10.2337/diabetes.50.9.2001

Published: 01 September 2001

View article titled, Decrease in β-Cell Mass Leads to Impaired Pulsatile Insulin Secretion, Reduced Postprandial Hepatic Insulin Clearance, and Relative Hyperglucagonemia in the Minipig

Meeting Abstracts

Recombinant human betacellulin promotes the neogenesis of beta-cells and ameliorates glucose intolerance in mice with diabetes induced by selective alloxan perfusion.

K Yamamoto, J Miyagawa, M Waguri, R Sasada, K Igarashi, M Li, T Nammo, M Moriwaki, A Imagawa, K Yamagata, H Nakajima, M Namba, Y Tochino, T Hanafusa, Y Matsuzawa

Diabetes 2000;49(12):2021–2027

https://doi.org/10.2337/diabetes.49.12.2021

Published: 01 December 2000

View article titled, Recombinant human betacellulin promotes the neogenesis of beta-cells and ameliorates glucose intolerance in mice with diabetes induced by selective alloxan perfusion.

Journal Articles

Demonstration of Two Different Processes of β-Cell Regeneration in a New Diabetic Mouse Model Induced by Selective Perfusion of Alloxan

Masako Waguri, Koji Yamamoto, Jun-ichiro Miyagawa, Yoshihiro Tochino, Katsumi Yamamori, Yoshitaka Kajimoto, Hiromu Nakajima, Hirotaka Watada, Issei Yoshiuchi, Naoto Itoh, Akihisa Imagawa, Mitsuyoshi Namba, Masamichi Kuwajima, Yoshimitsu Yamasaki, Toshiaki Hanafusa, Yuji Matsuzawa

Diabetes 1997;46(8):1281–1290

https://doi.org/10.2337/diab.46.8.1281

Published: 01 August 1997

View article titled, Demonstration of Two Different Processes of β-Cell Regeneration in a New Diabetic Mouse Model Induced by Selective Perfusion of Alloxan

Journal Articles

The Effect of Pioglitazone on Hepatic Glucose Uptake Measured With Indirect and Direct Methods in Alloxan-Induced Diabetic Dogs

Munehide Matsuhisa, Z Qing Shi, Calvin Wan, Michael Lekas, Carol D Rodgers, Adria Giacca, Ryuzo Kawamori, Mladen Vranic

Diabetes 1997;46(2):224–231

https://doi.org/10.2337/diab.46.2.224

Published: 01 February 1997

View article titled, The Effect of Pioglitazone on Hepatic Glucose Uptake Measured With Indirect and Direct Methods in Alloxan-Induced Diabetic Dogs

Journal Articles

Evidence for a Major Role for Glucagon in Regulation of Plasma Glucose in Conscious, Nondiabetic, and Alloxan-Induced Diabetic Rabbits

Christian L Brand, Peer N Jørgensen, Ivan Svendsen, Jens J Hoist

Diabetes 1996;45(8):1076–1083

https://doi.org/10.2337/diab.45.8.1076

Published: 01 August 1996

View article titled, Evidence for a Major Role for Glucagon in Regulation of Plasma Glucose in Conscious, Nondiabetic, and Alloxan-Induced Diabetic Rabbits

Journal Articles

Brain D1 Dopamine Receptor in Alloxan-Induced Diabetes

Melita Šalković, Zdravko Lacković

Diabetes 1992;41(9):1119–1121

https://doi.org/10.2337/diab.41.9.1119

Published: 01 September 1992

View article titled, Brain D1 Dopamine Receptor in Alloxan-Induced Diabetes

Journal Articles

Streptozocin- and Alloxan-Induced H₂O₂ Generation and DNA Fragmentation in Pancreatic Islets: H₂O₂ as Mediator for DNA Fragmentation

Nobuyuki Takasu, Ichiro Komiya, Takayuki Asawa, Yoshitaka Nagasawa, Takashi Yamada

Diabetes 1991;40(9):1141–1145

https://doi.org/10.2337/diab.40.9.1141

Published: 01 September 1991

View article titled, Streptozocin- and Alloxan-Induced H2O2 Generation and DNA Fragmentation in Pancreatic Islets: H2O2 as Mediator for DNA Fragmentation

Journal Articles

Inhibition of Diabetes-Associated Complications by Nucleophilic Compounds

Kshama Kumari, Shahid Umar, Veena Bansal, Maharaj K Sahib

Diabetes 1991;40(8):1079–1084

https://doi.org/10.2337/diab.40.8.1079

Published: 01 August 1991

View article titled, Inhibition of Diabetes-Associated Complications by Nucleophilic Compounds

NARROW

1748-P: Brucine Topical Administration Promotes Wound Healing through Downregulation of Proinflammatory Markers and Chemokine Expressions in Alloxan-Induced Diabetic Mice

Interleukin-6 Reduces β-Cell Oxidative Stress by Linking Autophagy With the Antioxidant Response

Long-term Hyperglycemia Naturally Induces Dental Caries but Not Periodontal Disease in Type 1 and Type 2 Diabetic Rodents

¹¹¹In-exendin Uptake in the Pancreas Correlates With the β-Cell Mass and Not With the α-Cell Mass

Ventromedial Hypothalamic Glucokinase Is an Important Mediator of the Counterregulatory Response to Insulin-Induced Hypoglycemia

Deletion of STAT-1 Pancreatic Islets Protects Against Streptozotocin-Induced Diabetes and Early Graft Failure but Not Against Late Rejection

Vascular Reactivity in Arterioles From Normal and Alloxan-Diabetic Mice: Studies on Single Perfused Islets

Postprandial Suppression of Glucagon Secretion Depends on Intact Pulsatile Insulin Secretion: Further Evidence for the Intraislet Insulin Hypothesis

Failure of Transplanted Bone Marrow Cells to Adopt a Pancreatic β-Cell Fate

Major Histocompatibility Complex–Linked Diabetes Susceptibility in NOD/Lt Mice : Subcongenic Analysis Localizes a Component of Idd16 at the H2-D End of the Diabetogenic H2^g7 Complex

Third Ventricular Alloxan Reversibly Impairs Glucose Counterregulatory Responses

ATP-Dependent K⁺ Channels Contribute to Local Metabolic Coronary Vasodilation in Experimental Diabetes

Decrease in β-Cell Mass Leads to Impaired Pulsatile Insulin Secretion, Reduced Postprandial Hepatic Insulin Clearance, and Relative Hyperglucagonemia in the Minipig

Recombinant human betacellulin promotes the neogenesis of beta-cells and ameliorates glucose intolerance in mice with diabetes induced by selective alloxan perfusion.

Demonstration of Two Different Processes of β-Cell Regeneration in a New Diabetic Mouse Model Induced by Selective Perfusion of Alloxan

The Effect of Pioglitazone on Hepatic Glucose Uptake Measured With Indirect and Direct Methods in Alloxan-Induced Diabetic Dogs

Evidence for a Major Role for Glucagon in Regulation of Plasma Glucose in Conscious, Nondiabetic, and Alloxan-Induced Diabetic Rabbits

Brain D1 Dopamine Receptor in Alloxan-Induced Diabetes

Streptozocin- and Alloxan-Induced H₂O₂ Generation and DNA Fragmentation in Pancreatic Islets: H₂O₂ as Mediator for DNA Fragmentation

Inhibition of Diabetes-Associated Complications by Nucleophilic Compounds

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