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Meeting Abstracts

1627-P: Enhancer Regulator MLL4 Programs Skeletal Muscle Metabolic Efficiency by Limiting AMPK-Mediated Fuel Catabolism

LIKUN YANG, LIN LIU, CHENYUN DING, TINGTING FU, ZHENG ZHOU, ZHENJI GAN

Diabetes 2023;72(Supplement_1):1627-P

https://doi.org/10.2337/db23-1627-P

Published: 20 June 2023

View article titled, 1627-P: Enhancer Regulator MLL4 Programs Skeletal Muscle Metabolic Efficiency by Limiting AMPK-Mediated Fuel Catabolism

Meeting Abstracts

228-LB: Metformin Alleviates Aging-Associated Metabolic Disorders through Intestinal AMPK-Mediated Gut Microbiome Alteration

ERYUN ZHANG, WENDONG HUANG

Diabetes 2023;72(Supplement_1):228-LB

https://doi.org/10.2337/db23-228-LB

Published: 20 June 2023

View article titled, 228-LB: Metformin Alleviates Aging-Associated Metabolic Disorders through Intestinal AMPK-Mediated Gut Microbiome Alteration

Meeting Abstracts

588-P: Probing the Role of Muscle Glycogen Resynthesis on Postexercise AMPK Activation and Metabolic Protein Abundance Using a Novel Genetic Model

SEONGEUN KWAK, AMY ZHENG, EDWARD B. ARIAS, HAIYAN WANG, XIUFANG PAN, DONGSHENG DUAN, YONGPING YUE, GREGORY D. CARTEE

Diabetes 2023;72(Supplement_1):588-P

https://doi.org/10.2337/db23-588-P

Published: 20 June 2023

View article titled, 588-P: Probing the Role of Muscle Glycogen Resynthesis on Postexercise AMPK Activation and Metabolic Protein Abundance Using a Novel Genetic Model

Meeting Abstracts

1507-P: Carnosic Acid–Induced Browning in 3T3-L1 Adipocytes Is Dependent on AMPK Activation

FILIP VLAVCHESKI, NICOLE TSAKIRIDIS, ADRIA GIACCA, EVANGELIA TSIANI

Diabetes 2023;72(Supplement_1):1507-P

https://doi.org/10.2337/db23-1507-P

Published: 20 June 2023

View article titled, 1507-P: Carnosic Acid–Induced Browning in 3T3-L1 Adipocytes Is Dependent on AMPK Activation

Meeting Abstracts

266-LB: SGLT2 Inhibition Improved Endurance Performance of db/db Mice Accompanied by an Increased Endogenous AMPK Activator in Skeletal Muscles

SHINTARO NAKAMURA, YASUTAKA MIYACHI, HISASHI YOKOMIZO, HIROKO OTSUKA, RYUICHI SAKAMOTO, MASATOMO TAKAHASHI, YOSHIHIRO IZUMI, TAKASHI MIYAZAWA, TAKESHI BAMBA, YOSHIHIRO OGAWA

Diabetes 2023;72(Supplement_1):266-LB

https://doi.org/10.2337/db23-266-LB

Published: 20 June 2023

View article titled, 266-LB: SGLT2 Inhibition Improved Endurance Performance of db/db Mice Accompanied by an Increased Endogenous AMPK Activator in Skeletal Muscles

Meeting Abstracts

1631-P: scEMC10 Suppresses Glucose Uptake in Skeletal Muscle via the Inhibition of AMPK Signaling

SHUOSHUO JIN, YAHAO WANG, KUANGYANG CHEN, JIARONG DAI, LIJIAO CHEN, SHAN LIU, XUANCHUN WANG

Diabetes 2023;72(Supplement_1):1631-P

https://doi.org/10.2337/db23-1631-P

Published: 20 June 2023

View article titled, 1631-P: scEMC10 Suppresses Glucose Uptake in Skeletal Muscle via the Inhibition of AMPK Signaling

Meeting Abstracts

259-LB: Loss of AMPK Induces Elongation of Preexisting Hepatic Fatty Acids, without Affecting DNL, during Fasting–Refeeding

JUSTIN A. FLETCHER, STANISLAW DEJA, SHAWN C. BURGESS, XIAORONG FU, MELISSA MAE R. INIGO, JEFFREY BROWNING, BLANKA KUCEJOVA

Diabetes 2023;72(Supplement_1):259-LB

https://doi.org/10.2337/db23-259-LB

Published: 20 June 2023

View article titled, 259-LB: Loss of AMPK Induces Elongation of Preexisting Hepatic Fatty Acids, without Affecting DNL, during Fasting–Refeeding

Meeting Abstracts

1605-P: Hepatic Glycogen Directly Regulates Gluconeogenesis in Energy Shortage through AMPK

BICHEN ZHANG, MORGAN M. JOHNSON, TIMOTHY YUAN, TAMMY-NHU NGUYEN, ALAN SALTIEL

Diabetes 2023;72(Supplement_1):1605-P

https://doi.org/10.2337/db23-1605-P

Published: 20 June 2023

View article titled, 1605-P: Hepatic Glycogen Directly Regulates Gluconeogenesis in Energy Shortage through AMPK

Journal Articles

Erratum. A High-Fat Diet AMPK α1 in Adipocytes to Induce Exosome Shedding and Nonalcoholic Fatty Liver Development In Vivo. Diabetes 2021;70:577–588

Chenghui Yan, Xiaoxiang Tian, Jiayin Li, Dan Liu, Ding Ye, Zhonglin Xie, Yaling Han, Ming-Hui Zou

Diabetes 2023;72(7):1035

https://doi.org/10.2337/db23-er07

Published: 15 May 2023

View article titled, Erratum. A High-Fat Diet AMPK α1 in Adipocytes to Induce Exosome Shedding and Nonalcoholic Fatty Liver Development In Vivo. Diabetes 2021;70:577–588

Journal Articles

Expression of Concern. Chaoyong He, Hongliang Li, Benoit Viollet, Ming-Hui Zou, and Zhonglin Xie. AMPK Suppresses Vascular Inflammation In Vivo by Inhibiting Signal Transducer and Activator of Transcription-1. Diabetes 2015;64:4285–4297. DOI: 10.2337/db15-0107 . PMID: 25858560. PMCID: PMC4657575

American Diabetes Association

Diabetes 2023;72(7):1038

https://doi.org/10.2337/db23-ec07c

Published: 15 May 2023

View article titled, Expression of Concern. Chaoyong He, Hongliang Li, Benoit Viollet, Ming-Hui Zou, and Zhonglin Xie. AMPK Suppresses Vascular Inflammation In Vivo by Inhibiting Signal Transducer and Activator of Transcription-1. Diabetes 2015;64:4285–4297. DOI: 10.2337/db15-0107 . PMID: 25858560. PMCID: PMC4657575

Journal Articles

Reduced Expression Level of Protein Phosphatase PPM1E Serves to Maintain Insulin Secretion in Type 2 Diabetes

Sevda Gheibi, Luis Rodrigo Cataldo, Alexander Hamilton, Mi Huang, Sebastian Kalamajski, Malin Fex, Hindrik Mulder

Diabetes 2023;72(4):455–466

https://doi.org/10.2337/db22-0472

Published: 20 January 2023

View article titled, Reduced Expression Level of Protein Phosphatase <em>PPM1E</em> Serves to Maintain Insulin Secretion in Type 2 Diabetes

Meeting Abstracts

1345-P: Low-Dose Colchicine/Metformin Combination Ameliorates NASH via Regulating AMPK/NRF2/GDF15 Axis in Mice

SUN AH HAM, HEE-YEON CHO, CHOLONG JEONG, JU HO YOUN

Diabetes 2022;71(Supplement_1):1345-P

https://doi.org/10.2337/db22-1345-P

Published: 01 June 2022

View article titled, 1345-P: Low-Dose Colchicine/Metformin Combination Ameliorates NASH via Regulating AMPK/NRF2/GDF15 Axis in Mice

Meeting Abstracts

199-OR: Exercise Decreases Mouse and Human Islet Senescence through Glucagon-Mediated AMPK Activation

PRISCILA CARAPETO, JIHO KAHNG, ANA BARBARA T. ALVES WAGNER, ROELAND MIDDELBEEK, MICHAEL F. HIRSHMAN, LAURIE J. GOODYEAR, CRISTINA AGUAYO-MAZZUCATO

Diabetes 2022;71(Supplement_1):199-OR

https://doi.org/10.2337/db22-199-OR

Published: 01 June 2022

View article titled, 199-OR: Exercise Decreases Mouse and Human Islet Senescence through Glucagon-Mediated AMPK Activation

Meeting Abstracts

386-P: ROCK1 Regulation of AMPK in the Development of Diabetic Nephropathy

YOSUKE NAGAI, KEIICHIRO MATOBA, KENSUKE SEKIGUCHI, YUSUKE TAKEDA, YASUSHI KANAZAWA, DAIJI KAWANAMI, KAZUNORI UTSUNOMIYA, RIMEI NISHIMURA

Diabetes 2022;71(Supplement_1):386-P

https://doi.org/10.2337/db22-386-P

Published: 01 June 2022

View article titled, 386-P: ROCK1 Regulation of AMPK in the Development of Diabetic Nephropathy

Meeting Abstracts

839-P: Pharmacological Inhibition of Mammalian INDY Ameliorates Western Diet–Induced NASH in Mice: Possible Implication of Fgf21-AMPK Signaling

NERMEEN EL-AGROUDY, GRIT ZAHN, CHRISTINE HERRMANN, GELTRUDE MINGRONE, TIAGO C. ALVES, ANDREAS L. BIRKENFELD

Diabetes 2022;71(Supplement_1):839-P

https://doi.org/10.2337/db22-839-P

Published: 01 June 2022

View article titled, 839-P: Pharmacological Inhibition of Mammalian INDY Ameliorates Western Diet–Induced NASH in Mice: Possible Implication of Fgf21-AMPK Signaling

Meeting Abstracts

1297-P: Berberine Derivatives as Novel Antidiabetes Agents Targeting Intestinal AMPK and Antimicrobial Peptide-Controlled Gut Microbiome

ERYUN ZHANG

Diabetes 2022;71(Supplement_1):1297-P

https://doi.org/10.2337/db22-1297-P

Published: 01 June 2022

View article titled, 1297-P: Berberine Derivatives as Novel Antidiabetes Agents Targeting Intestinal AMPK and Antimicrobial Peptide-Controlled Gut Microbiome

Journal Articles

Response to Comment on Wendt et al. Contraction-Mediated Glucose Transport in Skeletal Muscle Is Regulated by a Framework of AMPK, TBC1D1/4, and Rac1. Diabetes 2021;70:2796–2809

Alexandra Chadt, Hadi Al-Hasani

Diabetes 2022;71(3):e5

https://doi.org/10.2337/dbi21-0038

Published: 23 February 2022

View article titled, Response to Comment on Wendt et al. Contraction-Mediated Glucose Transport in Skeletal Muscle Is Regulated by a Framework of AMPK, TBC1D1/4, and Rac1. Diabetes 2021;70:2796–2809

Journal Articles

Comment on De Wendt et al. Contraction-Mediated Glucose Transport in Skeletal Muscle Is Regulated by a Framework of AMPK, TBC1D1/4, and Rac1. Diabetes 2021;70:2796–2809

Rasmus Kjøbsted, Jørgen F.P. Wojtaszewski

Diabetes 2022;71(3):e3–e4

https://doi.org/10.2337/db21-1036

Published: 23 February 2022

View article titled, Comment on De Wendt et al. Contraction-Mediated Glucose Transport in Skeletal Muscle Is Regulated by a Framework of AMPK, TBC1D1/4, and Rac1. Diabetes 2021;70:2796–2809

Journal Articles

Contraction-Mediated Glucose Transport in Skeletal Muscle Is Regulated by a Framework of AMPK, TBC1D1/4, and Rac1

Christian de Wendt, Lena Espelage, Samaneh Eickelschulte, Christian Springer, Laura Toska, Anna Scheel, Awovi Didi Bedou, Tim Benninghoff, Sandra Cames, Torben Stermann, Alexandra Chadt, Hadi Al-Hasani

Diabetes 2021;70(12):2796–2809

https://doi.org/10.2337/db21-0587

Published: 24 September 2021

View article titled, Contraction-Mediated Glucose Transport in Skeletal Muscle Is Regulated by a Framework of AMPK, TBC1D1/4, and Rac1

Journal Articles

Erratum. A High-Fat Diet Attenuates AMPK α1 in Adipocytes to Induce Exosome Shedding and Nonalcoholic Fatty Liver Development In Vivo. Diabetes 2021;70: 577–588

Chenghui Yan, Xiaoxiang Tian, Jiayin Li, Dan Liu, Ding Ye, Zhonglin Xie, Yaling Han, Ming-Hui Zou

Diabetes 2021;70(9):2160

https://doi.org/10.2337/db21-er09b

Published: 22 July 2021

View article titled, Erratum. A High-Fat Diet Attenuates AMPK α1 in Adipocytes to Induce Exosome Shedding and Nonalcoholic Fatty Liver Development In Vivo. Diabetes 2021;70: 577–588

NARROW

1627-P: Enhancer Regulator MLL4 Programs Skeletal Muscle Metabolic Efficiency by Limiting AMPK-Mediated Fuel Catabolism

228-LB: Metformin Alleviates Aging-Associated Metabolic Disorders through Intestinal AMPK-Mediated Gut Microbiome Alteration

588-P: Probing the Role of Muscle Glycogen Resynthesis on Postexercise AMPK Activation and Metabolic Protein Abundance Using a Novel Genetic Model

1507-P: Carnosic Acid–Induced Browning in 3T3-L1 Adipocytes Is Dependent on AMPK Activation

266-LB: SGLT2 Inhibition Improved Endurance Performance of db/db Mice Accompanied by an Increased Endogenous AMPK Activator in Skeletal Muscles

1631-P: scEMC10 Suppresses Glucose Uptake in Skeletal Muscle via the Inhibition of AMPK Signaling

259-LB: Loss of AMPK Induces Elongation of Preexisting Hepatic Fatty Acids, without Affecting DNL, during Fasting–Refeeding

1605-P: Hepatic Glycogen Directly Regulates Gluconeogenesis in Energy Shortage through AMPK

Erratum. A High-Fat Diet AMPK α1 in Adipocytes to Induce Exosome Shedding and Nonalcoholic Fatty Liver Development In Vivo. Diabetes 2021;70:577–588

Expression of Concern. Chaoyong He, Hongliang Li, Benoit Viollet, Ming-Hui Zou, and Zhonglin Xie. AMPK Suppresses Vascular Inflammation In Vivo by Inhibiting Signal Transducer and Activator of Transcription-1. Diabetes 2015;64:4285–4297. DOI: 10.2337/db15-0107 . PMID: 25858560. PMCID: PMC4657575

Reduced Expression Level of Protein Phosphatase PPM1E Serves to Maintain Insulin Secretion in Type 2 Diabetes

1345-P: Low-Dose Colchicine/Metformin Combination Ameliorates NASH via Regulating AMPK/NRF2/GDF15 Axis in Mice

199-OR: Exercise Decreases Mouse and Human Islet Senescence through Glucagon-Mediated AMPK Activation

386-P: ROCK1 Regulation of AMPK in the Development of Diabetic Nephropathy

839-P: Pharmacological Inhibition of Mammalian INDY Ameliorates Western Diet–Induced NASH in Mice: Possible Implication of Fgf21-AMPK Signaling

1297-P: Berberine Derivatives as Novel Antidiabetes Agents Targeting Intestinal AMPK and Antimicrobial Peptide-Controlled Gut Microbiome

Response to Comment on Wendt et al. Contraction-Mediated Glucose Transport in Skeletal Muscle Is Regulated by a Framework of AMPK, TBC1D1/4, and Rac1. Diabetes 2021;70:2796–2809

Comment on De Wendt et al. Contraction-Mediated Glucose Transport in Skeletal Muscle Is Regulated by a Framework of AMPK, TBC1D1/4, and Rac1. Diabetes 2021;70:2796–2809

Contraction-Mediated Glucose Transport in Skeletal Muscle Is Regulated by a Framework of AMPK, TBC1D1/4, and Rac1

Erratum. A High-Fat Diet Attenuates AMPK α1 in Adipocytes to Induce Exosome Shedding and Nonalcoholic Fatty Liver Development In Vivo. Diabetes 2021;70: 577–588

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