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Meeting Abstracts

1855-PUB: Generation and Identification of Pik3r3 Gene Pancreatic Beta-Cell Knockout Mice Model

XIAO-RONG ZHU
Journal: Diabetes
Diabetes 2023;72(Supplement_1):1855-PUB
https://doi.org/10.2337/db23-1855-PUB
Published: 23 June 2023
View article titled, 1855-PUB: Generation and Identification of Pik3r3 Gene Pancreatic Beta-Cell Knockout Mice Model
Meeting Abstracts

247-LB: Link between Hyperglycemia and Cognitive Deficits in T2DM Animal Model

LI CHEN, JIANGXIA NI, LINGGE FENG, XUEXIN ZHANG, QIUYAN WANG, YELIN CHEN
Journal: Diabetes
Diabetes 2023;72(Supplement_1):247-LB
https://doi.org/10.2337/db23-247-LB
Published: 20 June 2023
View article titled, 247-LB: Link between Hyperglycemia and Cognitive Deficits in T2DM Animal Model
Meeting Abstracts

367-OR: E-cigarette Vaping Exposure Increases Adipose 11ß-HSD1 Expression and Disturbs Glucose Homeostasis in Mice

JIAN WANG, JENNY LIU, YING WANG, SAMUEL C.J. KIM, ELIZABETH ESPINAL, RONG YANG, HUI ZHONG, XUESI M. SHAO, KABIRULLAH LUTFY, THEODORE FRIEDMAN, MEISHENG JIANG, YANJUN LIU
Journal: Diabetes
Diabetes 2023;72(Supplement_1):367-OR
https://doi.org/10.2337/db23-367-OR
Published: 20 June 2023
View article titled, 367-OR: E-cigarette Vaping Exposure Increases Adipose 11ß-HSD1 Expression and Disturbs Glucose Homeostasis in Mice
Meeting Abstracts

9-OR: Insulin Resistance (IR) and Kidney Oxidative Metabolism in People with Type 1 Diabetes (T1D)

GABRIEL RICHARD, CARISSA BIRZNIEKS, GUANSHI ZHANG, LYNETTE DRISCOLL, KALIE L. TOMMERDAHL, JENNIFER A. SCHAUB, ABHIJIT NAIK, VIJI NAIR, ALEXIS A. MACDONALD, SUSAN GROSS, VIRAL N. SHAH, LAURA PYLE, TIMOTHY B. VIGERS, JANET K. SNELL-BERGEON, IAN DE BOER, DANIËL VAN RAALTE, LU-PING LI, POTTUMARTHI V. PRASAD, PATRICIA E. LADD, BENNETT B. CHIN, DAVID CHERNEY, PHILLIP J. MCCOWN, FADHL ALAKWAA, MATTHIAS KRETZLER, KUMAR SHARMA, FRANK C. BROSIUS, III, ROBERT G. NELSON, KRISTEN J. NADEAU, PETTER BJORNSTAD
Journal: Diabetes
Diabetes 2023;72(Supplement_1):9-OR
https://doi.org/10.2337/db23-9-OR
Published: 20 June 2023
View article titled, 9-OR: Insulin Resistance (IR) and Kidney Oxidative Metabolism in People with Type 1 Diabetes (T1D)
Meeting Abstracts

1678-P: B6-Alms1-del Mice, a Metabolic Syndrome Animal Model, Shows Semaglutide Benefits on Obesity, Hyperglycemia, and NAFL

ZHONG CHEN, MAOMAO GAO, XINYUE ZHAO, ZHIYING LI, JING ZHAO, CUNXIANG JU, XIANG GAO
Journal: Diabetes
Diabetes 2023;72(Supplement_1):1678-P
https://doi.org/10.2337/db23-1678-P
Published: 20 June 2023
View article titled, 1678-P: B6-Alms1-del Mice, a Metabolic Syndrome Animal Model, Shows Semaglutide Benefits on Obesity, Hyperglycemia, and NAFL
Meeting Abstracts

1175-P: The Alteration of Serum Level and Expression of c-MET in Gestational Diabetes Mellitus (GDM)

HYUN JIN KIM, JUHEE LEE, YE WON JUNG, MINA LEE, JIMIN KIM, KYONG HYE JOUNG, BON JEONG KU
Journal: Diabetes
Diabetes 2023;72(Supplement_1):1175-P
https://doi.org/10.2337/db23-1175-P
Published: 20 June 2023
View article titled, 1175-P: The Alteration of Serum Level and Expression of c-MET in Gestational Diabetes Mellitus (GDM)
Meeting Abstracts

6-OR: Vascular Endothelial ROCK2 Deficiency Promotes Browning and Burning of White Adipose Tissue

YUSUKE TAKEDA, KEIICHIRO MATOBA, RIKAKO UKICHI, KENSUKE SEKIGUCHI, YOSUKE NAGAI, YASUSHI KANAZAWA, KAZUNORI UTSUNOMIYA, RIMEI NISHIMURA
Journal: Diabetes
Diabetes 2022;71(Supplement_1):6-OR
https://doi.org/10.2337/db22-6-OR
Published: 01 June 2022
View article titled, 6-OR: Vascular Endothelial ROCK2 Deficiency Promotes Browning and Burning of White Adipose Tissue
Meeting Abstracts

108-OR: The Effect of Human Pregnancy on Morphology of the Endocrine Pancreas

AOIFE M. EGAN, TRACY K. HER, ADRIAN VELLA, ALEKSEY MATVEYENKO
Journal: Diabetes
Diabetes 2022;71(Supplement_1):108-OR
https://doi.org/10.2337/db22-108-OR
Published: 01 June 2022
View article titled, 108-OR: The Effect of Human Pregnancy on Morphology of the Endocrine Pancreas
Meeting Abstracts

246-LB: Neonatal Microbes Stimulate Beta-Cell Development

JENNIFER H. HILL, KAREN GUILLEMIN, CHARLES L. MURTAUGH, JUNE ROUND
Journal: Diabetes
Diabetes 2022;71(Supplement_1):246-LB
https://doi.org/10.2337/db22-246-LB
Published: 01 June 2022
View article titled, 246-LB: Neonatal Microbes Stimulate Beta-Cell Development
Meeting Abstracts

1460-P: Tauroursodeoxycholic Acid (tudca) Improves the Morphofunction of Pancreatic Beta Cells in Postweaning Protein-Restricted Mice

LOHANNA M. BARRETO DOS SANTOS, THIAGO ARAUJO, BRUNA L. ALVES, SANDRA MARA FERREIRA, PRISCILA L. ZIMATH, JEAN F. VETTORAZZI, EVERARDO M. CARNEIRO
Journal: Diabetes
Diabetes 2022;71(Supplement_1):1460-P
https://doi.org/10.2337/db22-1460-P
Published: 01 June 2022
View article titled, 1460-P: Tauroursodeoxycholic Acid (tudca) Improves the Morphofunction of Pancreatic Beta Cells in Postweaning Protein-Restricted Mice
Meeting Abstracts

254-LB: EndoC-ßH5 Human Beta Cells—A Unique “Thaw and Go” Model for Accelerating Diabetes Research with Highly Functional and Ready-to-Use Human Beta Cells

HAMZA OLLEIK, BRUNO BLANCHI
Journal: Diabetes
Diabetes 2022;71(Supplement_1):254-LB
https://doi.org/10.2337/db22-254-LB
Published: 01 June 2022
View article titled, 254-LB: EndoC-ßH5 Human Beta Cells—A Unique “Thaw and Go” Model for Accelerating Diabetes Research with Highly Functional and Ready-to-Use Human Beta Cells
Meeting Abstracts

655-P: Multitarget Engagement Effect of a Novel Long-Acting Glucagon/GIP/GLP-1 Triple Agonist (HM15211) in Animal Model of NASH

JUNG KUK KIM, JONG SUK LEE, HYUNJOO KWON, EUNJIN PARK, JONGSOO LEE, SUNGMIN BAE, SANG HYUN LEE, IN YOUNG CHOI
Journal: Diabetes
Diabetes 2021;70(Supplement_1):655-P
https://doi.org/10.2337/db21-655-P
Published: 01 June 2021
View article titled, 655-P: Multitarget Engagement Effect of a Novel Long-Acting Glucagon/GIP/GLP-1 Triple Agonist (HM15211) in Animal Model of NASH
Meeting Abstracts

657-P: Potential Effect of a Novel Combination of GLP-1RA (efpeglenatide) and Long-Acting Glucagon Analog (HM15136) in Animal Models of Metabolic Disorders

JONG SUK LEE, JUNG KUK KIM, SEON MYEONG LEE, JAEHYUK CHOI, EUNJIN PARK, DAEJIN KIM, SUNGMIN BAE, SANG HYUN LEE, IN YOUNG CHOI
Journal: Diabetes
Diabetes 2021;70(Supplement_1):657-P
https://doi.org/10.2337/db21-657-P
Published: 01 June 2021
View article titled, 657-P: Potential Effect of a Novel Combination of GLP-1RA (efpeglenatide) and Long-Acting Glucagon Analog (HM15136) in Animal Models of Metabolic Disorders
Meeting Abstracts

217-LB: YH34160, a Novel Long-Acting GDF15 Fusion Protein, Elicits Potent and Sustained Body Weight Loss in Obese Animal Models

SEYOUNG LIM, JIEUN YANG, DO-HOON KIM, MI KYEONG JU, SUKYUNG KIM, YOUNG BONG PARK, BO RA SIM, JUNHWAN KIM, JONG GYUN KIM, SE-WOONG OH
Journal: Diabetes
Diabetes 2021;70(Supplement_1):217-LB
https://doi.org/10.2337/db21-217-LB
Published: 01 June 2021
View article titled, 217-LB: YH34160, a Novel Long-Acting GDF15 Fusion Protein, Elicits Potent and Sustained Body Weight Loss in Obese Animal Models
Meeting Abstracts

222-LB: Canonical Wnt Signaling Regulates Beta-Cell Neogenesis from Pancreatic Duct Cells

SOLOMON AFELIK, ZHAN YU
Journal: Diabetes
Diabetes 2021;70(Supplement_1):222-LB
https://doi.org/10.2337/db21-222-LB
Published: 01 June 2021
View article titled, 222-LB: Canonical Wnt Signaling Regulates Beta-Cell Neogenesis from Pancreatic Duct Cells
Meeting Abstracts

1606-P: Effect of Changes in Dark/Light Cycle on Physiological Homeostasis as a Confounding Prelude to Diabetes in Fischer 334 Animal Model

BALANEHRU SUBRAMANIAN, GANAPATHY RAMAKRISHNAN, PANNERSELVAM TAMILMARAN, BALAKRISHNAN SUNDARAKRISHNAN, KRISHNA SESHADRI
Journal: Diabetes
Diabetes 2020;69(Supplement_1):1606-P
https://doi.org/10.2337/db20-1606-P
Published: 01 June 2020
View article titled, 1606-P: Effect of Changes in Dark/Light Cycle on Physiological Homeostasis as a Confounding Prelude to Diabetes in Fischer 334 Animal Model
Meeting Abstracts

370-OR: Hepatic FGF21 Expression Is Under the Regulation of the Canonical Wnt Signaling Pathway

YASAMAN BADAKHSHI, WEIJUAN SHAO, LILI TIAN, TIANRU JIN
Journal: Diabetes
Diabetes 2020;69(Supplement_1):370-OR
https://doi.org/10.2337/db20-370-OR
Published: 01 June 2020
View article titled, 370-OR: Hepatic FGF21 Expression Is Under the Regulation of the Canonical Wnt Signaling Pathway
Meeting Abstracts

366-OR: Characterization of Gene Expression Networks That Are Oppositely Regulated by Human and Mouse Metabolic Disease Using a Humanized Mouse Model

HAIMING CAO
Journal: Diabetes
Diabetes 2020;69(Supplement_1):366-OR
https://doi.org/10.2337/db20-366-OR
Published: 01 June 2020
View article titled, 366-OR: Characterization of Gene Expression Networks That Are Oppositely Regulated by Human and Mouse Metabolic Disease Using a Humanized Mouse Model
Meeting Abstracts

604-P: Deficiency of Dedicator of Cytokinesis 5 Impairs Epidermal Wound Healing

YI ZHENG, HUA QU
Journal: Diabetes
Diabetes 2020;69(Supplement_1):604-P
https://doi.org/10.2337/db20-604-P
Published: 01 June 2020
View article titled, 604-P: Deficiency of Dedicator of Cytokinesis 5 Impairs Epidermal Wound Healing
Meeting Abstracts

225-LB: A High-Throughput CRISPR-Activation Screen Defines Human LncRNA Metabolic Regulators

YONGHE MA, HAIMING CAO
Journal: Diabetes
Diabetes 2020;69(Supplement_1):225-LB
https://doi.org/10.2337/db20-225-LB
Published: 01 June 2020
View article titled, 225-LB: A High-Throughput CRISPR-Activation Screen Defines Human LncRNA Metabolic Regulators