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Meeting Abstracts

461-P: Treatment with Mild Electrical Stimulation + Heat Shock (MET) Suppresses the Progression of Atherosclerosis in ApoE-Deficient Mice

RINTARO YOSHIZUMI, TATSUYA KONDO, TAKURO WATANABE, NOBUKAZU MIYAKAWA
Journal: Diabetes
Diabetes 2023;72(Supplement_1):461-P
https://doi.org/10.2337/db23-461-P
Published: 20 June 2023
View article titled, 461-P: Treatment with Mild Electrical Stimulation + Heat Shock (MET) Suppresses the Progression of Atherosclerosis in ApoE-Deficient Mice
Journal Articles

Genetically Predicted Glucose-Dependent Insulinotropic Polypeptide (GIP) Levels and Cardiovascular Disease Risk Are Driven by Distinct Causal Variants in the GIPR Region

Nicholas Bowker, Robert Hansford, Stephen Burgess, Christopher N. Foley, Victoria P.W. Auyeung, A. Mesut Erzurumluoglu, Isobel D. Stewart, Eleanor Wheeler, Maik Pietzner, Fiona Gribble, Frank Reimann, Pallav Bhatnagar, Matthew P. Coghlan, Nicholas J. Wareham, Claudia Langenberg
Journal: Diabetes
Diabetes 2021;70(11):2706–2719
https://doi.org/10.2337/db21-0103
Published: 23 August 2021
View article titled, Genetically Predicted Glucose-Dependent Insulinotropic Polypeptide (GIP) Levels and Cardiovascular Disease Risk Are Driven by Distinct Causal Variants in the <em>GIPR</em> Region
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Journal Articles

Specific NLRP3 Inhibition Protects Against Diabetes-Associated Atherosclerosis

Arpeeta Sharma, Judy S.Y. Choi, Nada Stefanovic, Annas Al-Sharea, Daniel S. Simpson, Nigora Mukhamedova, Karin Jandeleit-Dahm, Andrew J. Murphy, Dmitri Sviridov, James E. Vince, Rebecca H. Ritchie, Judy B. de Haan
Journal: Diabetes
Diabetes 2021;70(3):772–787
https://doi.org/10.2337/db20-0357
Published: 15 December 2020
View article titled, Specific NLRP3 Inhibition Protects Against Diabetes-Associated Atherosclerosis
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Meeting Abstracts

463-P: Deterioration of Atherosclerosis via Dysbiosis in ApoE Null Mice Fed with High-Salt Diet

TOMONORI KIMURA, YOSHITAKA HASHIMOTO, TAKAFUMI SENMARU, EMI USHIGOME, MASAHIDE HAMAGUCHI, MASAHIRO YAMAZAKI, MICHIAKI FUKUI
Journal: Diabetes
Diabetes 2020;69(Supplement_1):463-P
https://doi.org/10.2337/db20-463-P
Published: 01 June 2020
View article titled, 463-P: Deterioration of Atherosclerosis via Dysbiosis in ApoE Null Mice Fed with High-Salt Diet
Meeting Abstracts

2298-PUB: Estradiol Protects Female ApoE KO Mice against Nonalcoholic Steatohepatitis

GABRIELA V. MOREIRA, SANDRO L. MATOS, FELIPE N. CAMARGO, LAYANNE ARAUJO, GILSON M. MURATA, CARLA R.O. CARVALHO, JOAO PAULO CAMPOREZ
Journal: Diabetes
Diabetes 2020;69(Supplement_1):2298-PUB
https://doi.org/10.2337/db20-2298-PUB
Published: 01 June 2020
View article titled, 2298-PUB: Estradiol Protects Female ApoE KO Mice against Nonalcoholic Steatohepatitis
Journal Articles

Remnants of the Triglyceride-Rich Lipoproteins, Diabetes, and Cardiovascular Disease

Alan Chait, Henry N. Ginsberg, Tomas Vaisar, Jay W. Heinecke, Ira J. Goldberg, Karin E. Bornfeldt
Journal: Diabetes
Diabetes 2020;69(4):508–516
https://doi.org/10.2337/dbi19-0007
Published: 16 March 2020
View article titled, Remnants of the Triglyceride-Rich Lipoproteins, Diabetes, and Cardiovascular Disease
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Meeting Abstracts

478-P: Accelerating Atherosclerosis by Autoimmune Process in Nonobese Diabetic Mice Made ApoE Deficient by CRISPR/Cas9 Gene Editing

KYOUNGMIN PARK, QIAN LI, HAIYAN WANG, RONALD ST-LOUIS, HISASHI YOKOMIZO, ERNESTO MADDALONI, TAKANORI SHINJO, JIALIN FU, I-HSIEN WU, STEPHAN KISSLER, GEORGE L. KING
Journal: Diabetes
Diabetes 2019;68(Supplement_1):478-P
https://doi.org/10.2337/db19-478-P
Published: 01 June 2019
View article titled, 478-P: Accelerating Atherosclerosis by Autoimmune Process in Nonobese Diabetic Mice Made ApoE Deficient by CRISPR/Cas9 Gene Editing
Meeting Abstracts

482-P: Linagliptin Induces M2 Macrophage Polarization and Suppresses Progression of Atherosclerosis in High-Fat-Fed ApoE-Deficient Mice

SHUHEI NISHIDA, TAKESHI MATSUMURA, TAKAFUMI SENOKUCHI, NORIO ISHII, SAIKO MURAKAMI-NISHIDA, SARIE YAMADA, YUTARO MORITA, TOSHIAKI WADA, HIROYUKI MOTOSHIMA, TATSUYA KONDO, EIICHI ARAKI
Journal: Diabetes
Diabetes 2019;68(Supplement_1):482-P
https://doi.org/10.2337/db19-482-P
Published: 01 June 2019
View article titled, 482-P: Linagliptin Induces M2 Macrophage Polarization and Suppresses Progression of Atherosclerosis in High-Fat-Fed ApoE-Deficient Mice
Meeting Abstracts

483-P: Pioglitazone Suppresses Macrophage Proliferation in Apolipoprotein-e Deficient Mice by Activating PPARγ

SAIKO MURAKAMI-NISHIDA, TAKESHI MATSUMURA, SHUHEI NISHIDA, TAKAFUMI SENOKUCHI, NORIO ISHII, SARIE YAMADA, YUTARO MORITA, TOSHIAKI WADA, HIROYUKI MOTOSHIMA, TATSUYA KONDO, EIICHI ARAKI
Journal: Diabetes
Diabetes 2019;68(Supplement_1):483-P
https://doi.org/10.2337/db19-483-P
Published: 01 June 2019
View article titled, 483-P: Pioglitazone Suppresses Macrophage Proliferation in Apolipoprotein-e Deficient Mice by Activating PPARγ
Meeting Abstracts

2102-P: Upregulation of Adipose Tissue APOE Expression by ω3PUFA Supplementation Associates with Decreased Plasma FFA Levels and Improves Insulin Sensitivity in Obese Subjects

CASSANDRA RAU, TING LI, JAMES D. HERNANDEZ, MIA Y. MASUDA, XIAODONG ZHANG, PANWEN WANG, DAWN K. COLETTA, ELEANNA DEFILIPPIS
Journal: Diabetes
Diabetes 2019;68(Supplement_1):2102-P
https://doi.org/10.2337/db19-2102-P
Published: 01 June 2019
View article titled, 2102-P: Upregulation of Adipose Tissue APOE Expression by ω3PUFA Supplementation Associates with Decreased Plasma FFA Levels and Improves Insulin Sensitivity in Obese Subjects
Journal Articles

Lipoxins Protect Against Inflammation in Diabetes-Associated Atherosclerosis

Eoin P. Brennan, Muthukumar Mohan, Aaron McClelland, Monica de Gaetano, Christos Tikellis, Mariam Marai, Daniel Crean, Aozhi Dai, Ophelie Beuscart, Sinda Derouiche, Stephen P. Gray, Raelene Pickering, Sih Min Tan, Molly Godson-Treacy, Stephen Sheehan, Joseph F. Dowdall, Mary Barry, Orina Belton, Syed Tasadaque Ali-Shah, Patrick J. Guiry, Karin Jandeleit-Dahm, Mark E. Cooper, Catherine Godson, Phillip Kantharidis
Journal: Diabetes
Diabetes 2018;67(12):2657–2667
https://doi.org/10.2337/db17-1317
Published: 13 September 2018
View article titled, Lipoxins Protect Against Inflammation in Diabetes-Associated Atherosclerosis
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Includes: Supplementary data
Meeting Abstracts

Expression of ApoE Attenuates Differentiation of the White Adipose Tissue from ApoE-Knockout Diabetic Mice

JIANMIN RAN, XIAMING PAN, RUYI ZHANG, PING ZHU, RONGSHAO TAN, YAN LIU
Journal: Diabetes
Diabetes 2018;67(Supplement_1):613-P
https://doi.org/10.2337/db18-613-P
Published: 01 July 2018
View article titled, Expression of ApoE Attenuates Differentiation of the White Adipose Tissue from ApoE-Knockout Diabetic Mice
Meeting Abstracts

Tofogliflozin Suppresses the Progression of Atherosclerosis and Reduces Inflammation in Macrophages of STZ-Diabetic ApoE KO Mice due to Improvement of Glucose Tolerance

MASAHIKO IWAMOTO, NAOTO KUBOTA, TETSUYA KUBOTA, YOSHITAKA SAKURAI, NOBUHIRO WADA, ISEKI TAKAMOTO, SEIJI SHIODA, TAKASHI KADOWAKI
Journal: Diabetes
Diabetes 2018;67(Supplement_1):486-P
https://doi.org/10.2337/db18-486-P
Published: 01 July 2018
View article titled, Tofogliflozin Suppresses the Progression of Atherosclerosis and Reduces Inflammation in Macrophages of STZ-Diabetic ApoE KO Mice due to Improvement of Glucose Tolerance
Journal Articles

Metabolic Karma—The Atherogenic Legacy of Diabetes: The 2017 Edwin Bierman Award Lecture

Mark Emmanuel Cooper, Assam El-Osta, Terri Jean Allen, Anna Margareta Dorothea Watson, Merlin Christopher Thomas, Karin Agnes Maria Jandeleit-Dahm
Journal: Diabetes
Diabetes 2018;67(5):785–790
https://doi.org/10.2337/dbi18-0010
Published: 13 April 2018
View article titled, Metabolic Karma—The Atherogenic Legacy of Diabetes: The 2017 Edwin Bierman Award Lecture
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Journal Articles

Diabetes Reduces Severity of Aortic Aneurysms Depending on the Presence of Cell Division Autoantigen 1 (CDA1)

Jiaze Li, Pacific Huynh, Aozhi Dai, Tieqiao Wu, Yugang Tu, Bryna Chow, Helen Kiriazis, Xiao-Jun Du, Leon A. Bach, Jennifer L. Wilkinson-Berka, Erik Biros, Philip Walker, Maria Nataatmadja, Malcolm West, Jonathan Golledge, Terri J. Allen, Mark E. Cooper, Zhonglin Chai
Journal: Diabetes
Diabetes 2018;67(4):755–768
https://doi.org/10.2337/db17-0134
Published: 08 January 2018
View article titled, Diabetes Reduces Severity of Aortic Aneurysms Depending on the Presence of Cell Division Autoantigen 1 (CDA1)
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Includes: Supplementary data
Journal Articles

Metformin Suppresses Diabetes-Accelerated Atherosclerosis via the Inhibition of Drp1-Mediated Mitochondrial Fission

Qilong Wang, Miao Zhang, Gloria Torres, Shengnan Wu, Changhan Ouyang, Zhonglin Xie, Ming-Hui Zou
Journal: Diabetes
Diabetes 2017;66(1):193–205
https://doi.org/10.2337/db16-0915
Published: 13 October 2016
View article titled, Metformin Suppresses Diabetes-Accelerated Atherosclerosis via the Inhibition of Drp1-Mediated Mitochondrial Fission
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Includes: Supplementary data
Journal Articles

Atrasentan Reduces Albuminuria by Restoring the Glomerular Endothelial Glycocalyx Barrier in Diabetic Nephropathy

Margien G.S. Boels, M. Cristina Avramut, Angela Koudijs, Martijn J.C. Dane, Dae Hyun Lee, Johan van der Vlag, Abraham J. Koster, Anton Jan van Zonneveld, Ernst van Faassen, Hermann-Josef Gröne, Bernard M. van den Berg, Ton J. Rabelink
Journal: Diabetes
Diabetes 2016;65(8):2429–2439
https://doi.org/10.2337/db15-1413
Published: 25 March 2016
View article titled, Atrasentan Reduces Albuminuria by Restoring the Glomerular Endothelial Glycocalyx Barrier in Diabetic Nephropathy
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Includes: Supplementary data
Journal Articles

Targeting HSP90 Ameliorates Nephropathy and Atherosclerosis Through Suppression of NF-κB and STAT Signaling Pathways in Diabetic Mice

Iolanda Lazaro, Ainhoa Oguiza, Carlota Recio, Beñat Mallavia, Julio Madrigal-Matute, Julia Blanco, Jesus Egido, Jose-Luis Martin-Ventura, Carmen Gomez-Guerrero
Journal: Diabetes
Diabetes 2015;64(10):3600–3613
https://doi.org/10.2337/db14-1926
Published: 26 June 2015
View article titled, Targeting HSP90 Ameliorates Nephropathy and Atherosclerosis Through Suppression of NF-κB and STAT Signaling Pathways in Diabetic Mice
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Includes: Supplementary data
Journal Articles

Direct Endothelial Nitric Oxide Synthase Activation Provides Atheroprotection in Diabetes-Accelerated Atherosclerosis

Arpeeta Sharma, Stephanie Sellers, Nada Stefanovic, Cleo Leung, Sih Min Tan, Olivier Huet, David J. Granville, Mark E. Cooper, Judy B. de Haan, Pascal Bernatchez
Journal: Diabetes
Diabetes 2015;64(11):3937–3950
https://doi.org/10.2337/db15-0472
Published: 26 June 2015
View article titled, Direct Endothelial Nitric Oxide Synthase Activation Provides Atheroprotection in Diabetes-Accelerated Atherosclerosis
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Includes: Supplementary data
Journal Articles

Insulin Resistance Predicts Medial Temporal Hypermetabolism in Mild Cognitive Impairment Conversion to Alzheimer Disease

Auriel A. Willette, Nina Modanlo, Dimitrios Kapogiannis, for the Alzheimer’s Disease Neuroimaging Initiative
Journal: Diabetes
Diabetes 2015;64(6):1933–1940
https://doi.org/10.2337/db14-1507
Published: 09 January 2015
View article titled, Insulin Resistance Predicts Medial Temporal Hypermetabolism in Mild Cognitive Impairment Conversion to Alzheimer Disease
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Includes: Supplementary data