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Journal Articles

A Hybrid Insulin Epitope Maintains High 2D Affinity for Diabetogenic T Cells in the Periphery

Baoyu Liu, Jennifer D. Hood, Elizabeth M. Kolawole, Derek M. Woodruff, Dario A. Vignali, Maria Bettini, Brian D. Evavold
Journal: Diabetes
Diabetes 2020;69(3):381–391
https://doi.org/10.2337/db19-0399
Published: 05 December 2020
View article titled, A Hybrid Insulin Epitope Maintains High 2D Affinity for Diabetogenic T Cells in the Periphery
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Journal Articles

Maternal Type 1 Diabetes Reduces Autoantigen-Responsive CD4+ T Cells in Offspring

Jan Knoop, Anne Eugster, Anita Gavrisan, Ramona Lickert, Eva-Maria Sedlmeier, Sevina Dietz, Annett Lindner, Katharina Warncke, Nadine Hummel, Anette-Gabriele Ziegler, Ezio Bonifacio
Journal: Diabetes
Diabetes 2020;69(4):661–669
https://doi.org/10.2337/db19-0751
Published: 02 January 2020
View article titled, Maternal Type 1 Diabetes Reduces Autoantigen-Responsive CD4<sup>+</sup> T Cells in Offspring
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Includes: Supplementary data
Journal Articles

In This Issue of Diabetes

Journal: Diabetes
Diabetes 2019;68(9):1707–1708
https://doi.org/10.2337/db19-ti09
Published: 14 August 2019
View article titled, In This Issue of <em>Diabetes</em>
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Journal Articles

CCL21 Expression in β-Cells Induces Antigen-Expressing Stromal Cell Networks in the Pancreas and Prevents Autoimmune Diabetes in Mice

Freddy E. Gonzalez Badillo, Flavia Zisi Tegou, Maria M. Abreu, Riccardo Masina, Divya Sha, Mejdi Najjar, Shane H. Wright, Allison L. Bayer, Éva Korpos, Alberto Pugliese, R. Damaris Molano, Alice A. Tomei
Journal: Diabetes
Diabetes 2019;68(10):1990–2003
https://doi.org/10.2337/db19-0239
Published: 01 August 2019
View article titled, CCL21 Expression in β-Cells Induces Antigen-Expressing Stromal Cell Networks in the Pancreas and Prevents Autoimmune Diabetes in Mice
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Includes: Supplementary data
Journal Articles

The Evolving Landscape of Autoantigen Discovery and Characterization in Type 1 Diabetes

Anthony W. Purcell, Salvatore Sechi, Teresa P. DiLorenzo
Journal: Diabetes
Diabetes 2019;68(5):879–886
https://doi.org/10.2337/dbi18-0066
Published: 16 April 2019
View article titled, The Evolving Landscape of Autoantigen Discovery and Characterization in Type 1 Diabetes
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Journal Articles

Epitope Stealing as a Mechanism of Dominant Protection by HLA-DQ6 in Type 1 Diabetes

Menno van Lummel, David T.P. Buis, Cherish Ringeling, Arnoud H. de Ru, Jos Pool, George K. Papadopoulos, Peter A. van Veelen, Helena Reijonen, Jan W. Drijfhout, Bart O. Roep
Journal: Diabetes
Diabetes 2019;68(4):787–795
https://doi.org/10.2337/db18-0501
Published: 09 January 2019
View article titled, Epitope Stealing as a Mechanism of Dominant Protection by HLA-DQ6 in Type 1 Diabetes
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Includes: Supplementary data
Journal Articles

Immune Recognition of β-Cells: Neoepitopes as Key Players in the Loss of Tolerance

Eddie A. James, Massimo Pietropaolo, Mark J. Mamula
Journal: Diabetes
Diabetes 2018;67(6):1035–1042
https://doi.org/10.2337/dbi17-0030
Published: 15 May 2018
View article titled, Immune Recognition of β-Cells: Neoepitopes as Key Players in the Loss of Tolerance
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Journal Articles

Primary Human and Rat β-Cells Release the Intracellular Autoantigens GAD65, IA-2, and Proinsulin in Exosomes Together With Cytokine-Induced Enhancers of Immunity

Chiara Cianciaruso, Edward A. Phelps, Miriella Pasquier, Romain Hamelin, Davide Demurtas, Mohamed Alibashe Ahmed, Lorenzo Piemonti, Sachiko Hirosue, Melody A. Swartz, Michele De Palma, Jeffrey A. Hubbell, Steinunn Baekkeskov
Journal: Diabetes
Diabetes 2017;66(2):460–473
https://doi.org/10.2337/db16-0671
Published: 21 November 2016
View article titled, Primary Human and Rat β-Cells Release the Intracellular Autoantigens GAD65, IA-2, and Proinsulin in Exosomes Together With Cytokine-Induced Enhancers of Immunity
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Includes: Supplementary data
Journal Articles

New Players in the Field of T1D: Anti-Peripherin B Lymphocytes

Peggy L. Kendall
Journal: Diabetes
Diabetes 2016;65(7):1794–1796
https://doi.org/10.2337/dbi16-0017
Published: 13 June 2016
View article titled, New Players in the Field of T1D: Anti-Peripherin B Lymphocytes
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Journal Articles

Delving Into the Type 1 Diabetic Islet: Evidence That B-Cell Infiltration of Islets Is Linked to Local Hyperimmunity and Accelerated Progression to Disease

Michael R. Christie
Journal: Diabetes
Diabetes 2016;65(5):1146–1148
https://doi.org/10.2337/dbi16-0008
Published: 15 April 2016
View article titled, Delving Into the Type 1 Diabetic Islet: Evidence That B-Cell Infiltration of Islets Is Linked to Local Hyperimmunity and Accelerated Progression to Disease
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Journal Articles

Expression-Based Genome-Wide Association Study Links Vitamin D–Binding Protein With Autoantigenicity in Type 1 Diabetes

Keiichi Kodama, Zhiyuan Zhao, Kyoko Toda, Linda Yip, Rebecca Fuhlbrigge, Dongmei Miao, C. Garrison Fathman, Satoru Yamada, Atul J. Butte, Liping Yu
Journal: Diabetes
Diabetes 2016;65(5):1341–1349
https://doi.org/10.2337/db15-1308
Published: 16 March 2016
View article titled, Expression-Based Genome-Wide Association Study Links Vitamin D–Binding Protein With Autoantigenicity in Type 1 Diabetes
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Includes: Supplementary data
Journal Articles

B-Lymphocytes Expressing an Ig Specificity Recognizing the Pancreatic β-Cell Autoantigen Peripherin Are Potent Contributors to Type 1 Diabetes Development in NOD Mice

Caroline M. Leeth, Jeremy Racine, Harold D. Chapman, Berta Arpa, Jorge Carrillo, Jorge Carrascal, Qiming Wang, Jeremy Ratiu, Leire Egia-Mendikute, Estela Rosell-Mases, Thomas Stratmann, Joan Verdaguer, David V. Serreze
Journal: Diabetes
Diabetes 2016;65(7):1977–1987
https://doi.org/10.2337/db15-1606
Published: 09 March 2016
View article titled, B-Lymphocytes Expressing an Ig Specificity Recognizing the Pancreatic β-Cell Autoantigen Peripherin Are Potent Contributors to Type 1 Diabetes Development in NOD Mice
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Includes: Supplementary data
Journal Articles

Are Obesity-Related Insulin Resistance and Type 2 Diabetes Autoimmune Diseases?

Sue Tsai, Xavier Clemente-Casares, Xavier S. Revelo, Shawn Winer, Daniel A. Winer
Journal: Diabetes
Diabetes 2015;64(6):1886–1897
https://doi.org/10.2337/db14-1488
Published: 16 May 2015
View article titled, Are Obesity-Related Insulin Resistance and Type 2 Diabetes Autoimmune Diseases?
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Journal Articles

Comment on Rondas et al. Citrullinated Glucose-Regulated Protein 78 Is an Autoantigen in Type 1 Diabetes. Diabetes 2015;64:573–586

Wei-Li Yu, Yun Sun
Journal: Diabetes
Diabetes 2015;64(3):e4
https://doi.org/10.2337/db14-1463
Published: 17 February 2015
View article titled, Comment on Rondas et al. Citrullinated Glucose-Regulated Protein 78 Is an Autoantigen in Type 1 Diabetes. Diabetes 2015;64:573–586
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Journal Articles

Autoimmune Diabetes: Caught in a NET

Richard David G. Leslie, C. Bradford
Journal: Diabetes
Diabetes 2014;63(12):4018–4020
https://doi.org/10.2337/db14-1382
Published: 13 November 2014
View article titled, Autoimmune Diabetes: Caught in a NET
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Journal Articles

Citrullinated Glucose-Regulated Protein 78 Is an Autoantigen in Type 1 Diabetes

Dieter Rondas, Inne Crèvecoeur, Wannes D’Hertog, Gabriela Bomfim Ferreira, An Staes, Abhishek D. Garg, Decio L. Eizirik, Patrizia Agostinis, Kris Gevaert, Lut Overbergh, Chantal Mathieu
Journal: Diabetes
Diabetes 2015;64(2):573–586
https://doi.org/10.2337/db14-0621
Published: 09 September 2014
View article titled, Citrullinated Glucose-Regulated Protein 78 Is an Autoantigen in Type 1 Diabetes
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Includes: Supplementary data
Journal Articles

Autoantigen-Induced Focusing of Vβ13+ T Cells Precedes Onset of Autoimmune Diabetes in the LEW.1WR1 Rat

Ryan A. Eberwine, Laura Cort, Michael Habib, John P. Mordes, Elizabeth P. Blankenhorn
Journal: Diabetes
Diabetes 2014;63(2):596–604
https://doi.org/10.2337/db13-0462
Published: 16 January 2014
View article titled, Autoantigen-Induced Focusing of Vβ13<sup>+</sup> T Cells Precedes Onset of Autoimmune Diabetes in the LEW.1WR1 Rat
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Includes: Supplementary data
Journal Articles

Posttranslational Modification of HLA-DQ Binding Islet Autoantigens in Type 1 Diabetes

Menno van Lummel, Gaby Duinkerken, Peter A. van Veelen, Arnoud de Ru, Robert Cordfunke, Arnaud Zaldumbide, Iria Gomez-Touriño, Sefina Arif, Mark Peakman, Jan W. Drijfhout, Bart O. Roep
Journal: Diabetes
Diabetes 2014;63(1):237–247
https://doi.org/10.2337/db12-1214
Published: 13 December 2013
View article titled, Posttranslational Modification of HLA-DQ Binding Islet Autoantigens in Type 1 Diabetes
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Includes: Supplementary data
Journal Articles

Activation of Islet Autoreactive Naïve T Cells in Infants Is Influenced by Homeostatic Mechanisms and Antigen-Presenting Capacity

Anne-Kristin Heninger, Paolo Monti, Carmen Wilhelm, Petra Schwaiger, Denise Kuehn, Anette-G. Ziegler, Ezio Bonifacio
Journal: Diabetes
Diabetes 2013;62(6):2059–2066
https://doi.org/10.2337/db12-0942
Published: 17 May 2013
View article titled, Activation of Islet Autoreactive Naïve T Cells in Infants Is Influenced by Homeostatic Mechanisms and Antigen-Presenting Capacity
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Includes: Supplementary data
Journal Articles

Local Autoantigen Expression as Essential Gatekeeper of Memory T-Cell Recruitment to Islet Grafts in Diabetic Hosts

Gonnie M. Alkemade, Xavier Clemente-Casares, Zhenguo Yu, Bao-You Xu, Jinguo Wang, Sue Tsai, James R. Wright, Jr., Bart O. Roep, Pere Santamaria
Journal: Diabetes
Diabetes 2013;62(3):905–911
https://doi.org/10.2337/db12-0600
Published: 14 February 2013
View article titled, Local Autoantigen Expression as Essential Gatekeeper of Memory T-Cell Recruitment to Islet Grafts in Diabetic Hosts
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Includes: Supplementary data