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Journal Articles

The Impact of Different Implantation Sites and Sex on the Differentiation of Human Pancreatic Endoderm Cells Into Insulin-Secreting Cells In Vivo

Nelly Saber, Cara E. Ellis, Diepiriye G. Iworima, Robert K. Baker, Alireza Rezania, Timothy J. Kieffer

Diabetes 2023;72(5):590–598

DOI: https://doi.org/10.2337/db22-0692

Published: 06 February 2023

View article titled, The Impact of Different Implantation Sites and Sex on the Differentiation of Human Pancreatic Endoderm Cells Into Insulin-Secreting Cells In Vivo

Journal Articles

Lower Hepatic Fat Is Associated With Improved Insulin Secretion in a High-Risk Prediabetes Subphenotype During Lifestyle Intervention

Diabetes 2023;72(3):362–366

DOI: https://doi.org/10.2337/db22-0441

Published: 16 December 2022

View article titled, Lower Hepatic Fat Is Associated With Improved Insulin Secretion in a High-Risk Prediabetes Subphenotype During Lifestyle Intervention

Journal Articles

Impaired Diurnal Pattern of Meal Tolerance and Insulin Sensitivity in Type 2 Diabetes: Implications for Therapy

Yogesh Yadav, Davide Romeres, Claudio Cobelli, Chiara Dalla Man, Rickey Carter, Ananda Basu, Rita Basu

Diabetes 2023;72(2):223–232

DOI: https://doi.org/10.2337/db22-0238

Published: 08 November 2022

View article titled, Impaired Diurnal Pattern of Meal Tolerance and Insulin Sensitivity in Type 2 Diabetes: Implications for Therapy

Journal Articles

Cathepsin D Drives the Formation of Hybrid Insulin Peptides Relevant to the Pathogenesis of Type 1 Diabetes

Samantha A. Crawford, Timothy A. Wiles, Janet M. Wenzlau, Roger L. Powell, Gene Barbour, Mylinh Dang, Jason Groegler, Jessie M. Barra, KaLia S. Burnette, Anita C. Hohenstein, Rocky L. Baker, Hubert M. Tse, Kathryn Haskins, Thomas Delong

Diabetes 2022;71(12):2793–2803

DOI: https://doi.org/10.2337/db22-0303

Published: 30 August 2022

View article titled, Cathepsin D Drives the Formation of Hybrid Insulin Peptides Relevant to the Pathogenesis of Type 1 Diabetes

Journal Articles

The p66^Shc Protein Mediates Insulin Resistance and Secretory Dysfunction in Pancreatic β-Cells Under Lipotoxic Conditions

Giuseppina Biondi, Nicola Marrano, Lucia Dipaola, Anna Borrelli, Martina Rella, Rossella D’Oria, Valentina A. Genchi, Cristina Caccioppoli, Immacolata Porreca, Angelo Cignarelli, Sebastio Perrini, Piero Marchetti, Leonardo Vincenti, Luigi Laviola, Francesco Giorgino, Annalisa Natalicchio

Diabetes 2022;71(8):1763–1771

DOI: https://doi.org/10.2337/db21-1066

Published: 21 August 2022

View article titled, The p66<sup>Shc</sup> Protein Mediates Insulin Resistance and Secretory Dysfunction in Pancreatic β-Cells Under Lipotoxic Conditions

Journal Articles

Endogenous Glucose-Dependent Insulinotropic Polypeptide Contributes to Sitagliptin-Mediated Improvement in β-Cell Function in Patients With Type 2 Diabetes

Signe Stensen, Lærke S. Gasbjerg, Mette M. Rosenkilde, Tina Vilsbøll, Jens J. Holst, Bolette Hartmann, Mikkel B. Christensen, Filip K. Knop

Diabetes 2022;71(10):2209–2221

DOI: https://doi.org/10.2337/db22-0059

Published: 07 July 2022

View article titled, Endogenous Glucose-Dependent Insulinotropic Polypeptide Contributes to Sitagliptin-Mediated Improvement in β-Cell Function in Patients With Type 2 Diabetes

Meeting Abstracts

259-OR: Stem Cell–Derived, Fully Differentiated Islet Cells for Type 1 Diabetes

JAMES F. MARKMANN, ALI NAJI, MICHAEL R. RICKELS, MARIA ALBA, GAUTHAM MARIGOWDA, LEORAH ROSS, CHENKUN WANG, FELICIA PAGLIUCA, BASTIANO SANNA, LESLIE S. KEAN, ANNE L. PETERS, PIOTR WITKOWSKI, CAMILLO RICORDI

Diabetes 2022;71(Supplement_1):259-OR

DOI: https://doi.org/10.2337/db22-259-OR

Published: 01 June 2022

View article titled, 259-OR: Stem Cell–Derived, Fully Differentiated Islet Cells for Type 1 Diabetes

Meeting Abstracts

1266-P: Random C-Peptide Testing Identified One-Tenth of Thai Adult Patients Misdiagnosed with Type 1 Diabetes Mellitus

YOTSAPON THEWJITCHAROEN, SOONTAREE NAKASATIEN, SIRIWAN BUTADEJ, EKGALUCK WANOTHAYAROJ, SIRINATE KRITTIYAWONG, THEP HIMATHONGKAM

Diabetes 2022;71(Supplement_1):1266-P

DOI: https://doi.org/10.2337/db22-1266-P

Published: 01 June 2022

View article titled, 1266-P: Random C-Peptide Testing Identified One-Tenth of Thai Adult Patients Misdiagnosed with Type 1 Diabetes Mellitus

Meeting Abstracts

1386-P: Confirmation of the Criteria for Insulin Administration at the Start of Steroid Therapy

SHIZUKA KANEKO, KAZUYA MOTOHASHI, TOMOKO MINAMI, YOKO UEBA, TOMOAKI OSUGI, SHINSUKE TOKUMOTO

Diabetes 2022;71(Supplement_1):1386-P

DOI: https://doi.org/10.2337/db22-1386-P

Published: 01 June 2022

View article titled, 1386-P: Confirmation of the Criteria for Insulin Administration at the Start of Steroid Therapy

Meeting Abstracts

1134-P: Interlaboratory Standardization of C-Peptide Assays Using Certified Reference Material Corrected for Peptide Modifications

ZENGRU WU, KUANYSH KABYTAEV, JIANYING MU, SHAWN CONNOLLY, MICHAEL J. MCPHAUL, RANDIE R. LITTLE

Diabetes 2022;71(Supplement_1):1134-P

DOI: https://doi.org/10.2337/db22-1134-P

Published: 01 June 2022

View article titled, 1134-P: Interlaboratory Standardization of C-Peptide Assays Using Certified Reference Material Corrected for Peptide Modifications

Meeting Abstracts

1254-P: Genetic Prediction of C-Peptide Trajectory before Type 1 Diabetes Diagnosis in TrialNet

TAYLOR M. TRIOLO, HEMANG M. PARIKH, MUSTAFA TOSUR, PETER GOTTLIEB, RICHARD A. ORAM, SUNA ONENGUT-GUMUSCU, JEFFREY KRISCHER, STEPHEN S. RICH, ANDREA STECK, MARIA J. REDONDO

Diabetes 2022;71(Supplement_1):1254-P

DOI: https://doi.org/10.2337/db22-1254-P

Published: 01 June 2022

View article titled, 1254-P: Genetic Prediction of C-Peptide Trajectory before Type 1 Diabetes Diagnosis in TrialNet

Meeting Abstracts

1250-P: Identifying Pediatric A-ß+ Ketosis-Prone Diabetes (KPD)

ELIZABETH A. KUBOTA-MISHRA, XIAOFAN C. HUANG, CHARLES G. MINARD, MARCELA ASTUDILLO, AHMAD K. REFAEY, GRACIELA MONTES, STEPHANIE SISLEY, ASHOK BALASUBRAMANYAM, MARIA J. REDONDO, MUSTAFA TOSUR, RADIANT STUDY GROUP

Diabetes 2022;71(Supplement_1):1250-P

DOI: https://doi.org/10.2337/db22-1250-P

Published: 01 June 2022

View article titled, 1250-P: Identifying Pediatric A-ß+ Ketosis-Prone Diabetes (KPD)

Meeting Abstracts

1118-P: Prediction of Clamp-Derived Insulin Sensitivity in African Americans from Clinical Risk Factors

LAUREN A. FOWLER, VIBHU PARCHA, CATHARINE COUCH, W. TIMOTHY GARVEY, BARBARA GOWER

Diabetes 2022;71(Supplement_1):1118-P

DOI: https://doi.org/10.2337/db22-1118-P

Published: 01 June 2022

View article titled, 1118-P: Prediction of Clamp-Derived Insulin Sensitivity in African Americans from Clinical Risk Factors

Meeting Abstracts

1045-P: Relative Cord Hyperleptinaemia Is Associated with Higher Cord C Peptide and Lower Birthweight in Male but Not Female Neonates Born to Overweight/Obese Women

JINCY IMMANUEL, GERNOT DESOYE, MIREILLE VANPOPPEL, ALEXANDRA KAUTZKY-WILLER, ROSA CORCOY, ALESSANDRA BERTOLOTTO, FIDELMA P. DUNNE, JÜRGEN HARREITER, LISE LOTTE TORVIN ANDERSEN, DORTE M. JENSEN, ELISABETH R. MATHIESEN, DAVID J. HILL, PETER DAMM, FRANK J. SNOEK, JUAN M. ADELANTADO, EWA WENDER-OZEGOWSKA, DAVID SIMMONS

Diabetes 2022;71(Supplement_1):1045-P

DOI: https://doi.org/10.2337/db22-1045-P

Published: 01 June 2022

View article titled, 1045-P: Relative Cord Hyperleptinaemia Is Associated with Higher Cord C Peptide and Lower Birthweight in Male but Not Female Neonates Born to Overweight/Obese Women

Meeting Abstracts

1211-P: Associations of C-peptide, HOMA2, and GADA with Insulin Initiation and Risk of Hypoglycemia in Type 2 Diabetes

BAOQI FAN, ERIC S.H. LAU, HONGJIANG WU, MAI SHI, AIMIN YANG, CADMON K.P. LIM, ALICE P. KONG, ELAINE CHOW, RONALD C. MA, ANDREA LUK, JULIANA C. CHAN

Diabetes 2022;71(Supplement_1):1211-P

DOI: https://doi.org/10.2337/db22-1211-P

Published: 01 June 2022

View article titled, 1211-P: Associations of C-peptide, HOMA2, and GADA with Insulin Initiation and Risk of Hypoglycemia in Type 2 Diabetes

Meeting Abstracts

825-P: Composite Glucose and C-Peptide Endpoints Show Early Efficacy in Recent-Onset Type 1 Diabetes (T1D) Clinical Trials

LAURA M. JACOBSEN, DAVID D. CUTHBERTSON, MICHAEL J. HALLER, HEBA M. ISMAIL, EMILY K. SIMS, STEPHEN E. GITELMAN, DIANE K. WHERRETT, ANTOINETTE MORAN, MARK A. ATKINSON, ALBERTO PUGLIESE, PETER GOTTLIEB, JAY SOSENKO

Diabetes 2022;71(Supplement_1):825-P

DOI: https://doi.org/10.2337/db22-825-P

Published: 01 June 2022

View article titled, 825-P: Composite Glucose and C-Peptide Endpoints Show Early Efficacy in Recent-Onset Type 1 Diabetes (T1D) Clinical Trials

Meeting Abstracts

1286-P: Plasma-Induced Signatures Measured at Type 1 Diabetes (T1D) Onset Correlate with Post-onset Beta-Cell Function

AMINA BEDRAT, SHUANG JIA, MARK ROETHLE, KRISTEN DEW, SUSANNE M. CABRERA, CHIEN-WEI LIN, MARTIN HESSNER

Diabetes 2022;71(Supplement_1):1286-P

DOI: https://doi.org/10.2337/db22-1286-P

Published: 01 June 2022

View article titled, 1286-P: Plasma-Induced Signatures Measured at Type 1 Diabetes (T1D) Onset Correlate with Post-onset Beta-Cell Function

Meeting Abstracts

1324-P: Short-Term Effects of Glycemia-Lowering Medications on ß-Cell Function in the GRADE Study

NEDA RASOULI, JEANINE ALBU, ROBERT M. COHEN, RALPH A. DEFRONZO, ELSA DIAZ, ALOKANANDA GHOSH, JOSE A. LUCHSINGER, JANET B. MCGILL, LAURE SAYYED KASSEM, WILLIAM SIVITZ, WILLIAM V. TAMBORLANE, KRISTINA UTZSCHNEIDER, NAJI YOUNES, STEVEN E. KAHN, GRADE RESEARCH GROUP

Diabetes 2022;71(Supplement_1):1324-P

DOI: https://doi.org/10.2337/db22-1324-P

Published: 01 June 2022

View article titled, 1324-P: Short-Term Effects of Glycemia-Lowering Medications on ß-Cell Function in the GRADE Study

Meeting Abstracts

288-OR: Effect of 24 Months of Optimised Glucose Control on Residual C-Peptide Secretion in Youth with New Onset Type 1 Diabetes (T1D)

CHARLOTTE K. BOUGHTON, JULIA WARE, JANET M. ALLEN, MALGORZATA E. WILINSKA, SARA HARTNELL, AJAY THANKAMONY, TABITHA RANDELL, ATRAYEE GHATAK, RACHEL BESSER, DANIELA ELLERI, NICOLA TREVELYAN, FIONA CAMPBELL, JUDY SIBAYAN, RYAN BAILEY, PETER CALHOUN, GARETH J. DUNSEATH, ROMAN HOVORKA, CLOUD CONSORTIUM

Diabetes 2022;71(Supplement_1):288-OR

DOI: https://doi.org/10.2337/db22-288-OR

Published: 01 June 2022

View article titled, 288-OR: Effect of 24 Months of Optimised Glucose Control on Residual C-Peptide Secretion in Youth with New Onset Type 1 Diabetes (T1D)

Journal Articles

Circulating C-Peptide Levels in Living Children and Young People and Pancreatic β-Cell Loss in Pancreas Donors Across Type 1 Diabetes Disease Duration

Alice L.J. Carr, Jamie R.J. Inshaw, Christine S. Flaxman, Pia Leete, Rebecca C. Wyatt, Lydia A. Russell, Matthew Palmer, Dmytro Prasolov, Thomas Worthington, Bethany Hull, Linda S. Wicker, David B. Dunger, Richard A. Oram, Noel G. Morgan, John A. Todd, Sarah J. Richardson, Rachel E.J. Besser

Diabetes 2022;71(7):1591–1596

DOI: https://doi.org/10.2337/db22-0097

Published: 02 May 2022

View article titled, Circulating C-Peptide Levels in Living Children and Young People and Pancreatic β-Cell Loss in Pancreas Donors Across Type 1 Diabetes Disease Duration

NARROW

The Impact of Different Implantation Sites and Sex on the Differentiation of Human Pancreatic Endoderm Cells Into Insulin-Secreting Cells In Vivo

Lower Hepatic Fat Is Associated With Improved Insulin Secretion in a High-Risk Prediabetes Subphenotype During Lifestyle Intervention

Impaired Diurnal Pattern of Meal Tolerance and Insulin Sensitivity in Type 2 Diabetes: Implications for Therapy

Cathepsin D Drives the Formation of Hybrid Insulin Peptides Relevant to the Pathogenesis of Type 1 Diabetes

The p66^Shc Protein Mediates Insulin Resistance and Secretory Dysfunction in Pancreatic β-Cells Under Lipotoxic Conditions

Endogenous Glucose-Dependent Insulinotropic Polypeptide Contributes to Sitagliptin-Mediated Improvement in β-Cell Function in Patients With Type 2 Diabetes

259-OR: Stem Cell–Derived, Fully Differentiated Islet Cells for Type 1 Diabetes

1266-P: Random C-Peptide Testing Identified One-Tenth of Thai Adult Patients Misdiagnosed with Type 1 Diabetes Mellitus

1386-P: Confirmation of the Criteria for Insulin Administration at the Start of Steroid Therapy

1134-P: Interlaboratory Standardization of C-Peptide Assays Using Certified Reference Material Corrected for Peptide Modifications

1254-P: Genetic Prediction of C-Peptide Trajectory before Type 1 Diabetes Diagnosis in TrialNet

1250-P: Identifying Pediatric A-ß+ Ketosis-Prone Diabetes (KPD)

1118-P: Prediction of Clamp-Derived Insulin Sensitivity in African Americans from Clinical Risk Factors

1045-P: Relative Cord Hyperleptinaemia Is Associated with Higher Cord C Peptide and Lower Birthweight in Male but Not Female Neonates Born to Overweight/Obese Women

1211-P: Associations of C-peptide, HOMA2, and GADA with Insulin Initiation and Risk of Hypoglycemia in Type 2 Diabetes

825-P: Composite Glucose and C-Peptide Endpoints Show Early Efficacy in Recent-Onset Type 1 Diabetes (T1D) Clinical Trials

1286-P: Plasma-Induced Signatures Measured at Type 1 Diabetes (T1D) Onset Correlate with Post-onset Beta-Cell Function

1324-P: Short-Term Effects of Glycemia-Lowering Medications on ß-Cell Function in the GRADE Study

288-OR: Effect of 24 Months of Optimised Glucose Control on Residual C-Peptide Secretion in Youth with New Onset Type 1 Diabetes (T1D)

Circulating C-Peptide Levels in Living Children and Young People and Pancreatic β-Cell Loss in Pancreas Donors Across Type 1 Diabetes Disease Duration

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