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Journal Articles

Resolving spatiotemporal electrical signaling within the islet via CMOS microelectrode arrays

Anne Gresch, Jana Osthues, Jan D. Hüwel, Jennifer K. Briggs, Tim Berger, Ruben Koch, Thomas Deickert, Christian Beecks, Richard K.P. Benninger, Martina Düfer

Diabetes db230870

https://doi.org/10.2337/db23-0870

Published: 25 November 2024

View article titled, Resolving spatiotemporal electrical signaling within the islet via CMOS microelectrode arrays

Journal Articles

Electrophysiological Characterization of Inducible Pluripotent Stem Cell–Derived Human β-Like Cells and an SLC30A8 Disease Model

Manon Jaffredo, Nicole A.J. Krentz, Benoite Champon, Claire E. Duff, Sameena Nawaz, Nicola Beer, Christian Honore, Anne Clark, Patrik Rorsman, Jochen Lang, Anna L. Gloyn, Matthieu Raoux, Benoit Hastoy

Diabetes 2024;73(8):1255–1265

https://doi.org/10.2337/db23-0776

Published: 22 May 2024

View article titled, Electrophysiological Characterization of Inducible Pluripotent Stem Cell–Derived Human β-Like Cells and an SLC30A8 Disease Model

Journal Articles

Do We Need a New Hypothesis for K_ATP Closure in β-Cells? Distinguishing the Baby From the Bathwater

Leslie Sherwin Satin, Jeremías Corradi, Arthur Stewart Sherman

Diabetes 2024;73(6):844–848

https://doi.org/10.2337/db24-0131

Published: 19 April 2024

View article titled, Do We Need a New Hypothesis for KATP Closure in β-Cells? Distinguishing the Baby From the Bathwater

Journal Articles

The Ailing β-Cell in Diabetes: Insights From a Trip to the ER: The 2023 Outstanding Scientific Achievement Award Lecture

Carmella Evans-Molina

Diabetes 2024;73(4):545–553

https://doi.org/10.2337/dbi23-0030

Published: 20 March 2024

View article titled, The Ailing β-Cell in Diabetes: Insights From a Trip to the ER: The 2023 Outstanding Scientific Achievement Award Lecture

Journal Articles

Protease-Activated Receptor 1–Mediated Damage of Podocytes in Diabetic Nephropathy

Ruslan Bohovyk, Sherif Khedr, Vladislav Levchenko, Mariia Stefanenko, Marharyta Semenikhina, Olha Kravtsova, Elena Isaeva, Aron M. Geurts, Christine A. Klemens, Oleg Palygin, Alexander Staruschenko

Diabetes 2023;72(12):1795–1808

https://doi.org/10.2337/db23-0032

Published: 18 September 2023

View article titled, Protease-Activated Receptor 1–Mediated Damage of Podocytes in Diabetic Nephropathy

Meeting Abstracts

1512-P: The Novel Roles of Intracellular Calcium and Phosphoinositides in Insulin Signaling and Metabolic Disease

JIN-WOOK LEE, YUNJAE JUNG, SEUNG-SOON IM, DAE HO LEE, HWA-YONG LEE, IN SUN HONG, OK-HEE KIM, BYUNG-CHUL OH

Diabetes 2023;72(Supplement_1):1512-P

https://doi.org/10.2337/db23-1512-P

Published: 20 June 2023

View article titled, 1512-P: The Novel Roles of Intracellular Calcium and Phosphoinositides in Insulin Signaling and Metabolic Disease

Meeting Abstracts

1777-P: Three-Dimensional Imaging Reveals Pancreatic Islet Fast Calcium Wave Origin Formation

YI YU

Diabetes 2023;72(Supplement_1):1777-P

https://doi.org/10.2337/db23-1777-P

Published: 20 June 2023

View article titled, 1777-P: Three-Dimensional Imaging Reveals Pancreatic Islet Fast Calcium Wave Origin Formation

Meeting Abstracts

1650-P: Characterizing the Mechanism of Action of the Lipokine 12,13-diHOME

JARED I. SENFELD, MATTHEW LYNES, SEAN KODANI, KIN SING STEPHEN LEE, YU-HUA TSENG

Diabetes 2023;72(Supplement_1):1650-P

https://doi.org/10.2337/db23-1650-P

Published: 20 June 2023

View article titled, 1650-P: Characterizing the Mechanism of Action of the Lipokine 12,13-diHOME

Meeting Abstracts

1558-P: The Mitochondrial Calcium Uniporter Regulates Hepatic Mitochondrial Oxidation and Intracellular Redox In Vivo

TRACI E. LAMOIA, BRANDON T. HUBBARD, MATEUS GUERRA, RUSSELL GOODMAN, MICHAEL H. NATHANSON, GERALD I. SHULMAN

Diabetes 2023;72(Supplement_1):1558-P

https://doi.org/10.2337/db23-1558-P

Published: 20 June 2023

View article titled, 1558-P: The Mitochondrial Calcium Uniporter Regulates Hepatic Mitochondrial Oxidation and Intracellular Redox In Vivo

Meeting Abstracts

1767-P: “Leader” ß-Cells within the Pancreatic Islet Are a Functionally Stable Subpopulation In Vitro and In Vivo

LUIS F. DELGADILLO SILVA, GUY A. RUTTER, PAULINE L. CHABOSSEAU, AUDREY PROVENCHER-GIRARD, ALEXANDRE PRAT, LIVIA LOPEZ NORIEGA

Diabetes 2023;72(Supplement_1):1767-P

https://doi.org/10.2337/db23-1767-P

Published: 20 June 2023

View article titled, 1767-P: “Leader” ß-Cells within the Pancreatic Islet Are a Functionally Stable Subpopulation In Vitro and In Vivo

Meeting Abstracts

219-LB: The Mitochondrial Calcium Uniporter Regulates Hepatic Lipid Accumulation and Mitochondrial Oxidation

TRACI E. LAMOIA, BRANDON T. HUBBARD, MATEUS GUERRA, RUSSELL GOODMAN, MICHAEL H. NATHANSON, VAMSI MOOTHA, GERALD I. SHULMAN

Diabetes 2022;71(Supplement_1):219-LB

https://doi.org/10.2337/db22-219-LB

Published: 01 June 2022

View article titled, 219-LB: The Mitochondrial Calcium Uniporter Regulates Hepatic Lipid Accumulation and Mitochondrial Oxidation

Meeting Abstracts

1487-PUB: Fostering the Health Literacy of Younger Generations

SHIZUKA KANEKO, KAZUKO KAMIYA

Diabetes 2022;71(Supplement_1):1487-PUB

https://doi.org/10.2337/db22-1487-PUB

Published: 01 June 2022

View article titled, 1487-PUB: Fostering the Health Literacy of Younger Generations

Meeting Abstracts

314-OR: Synaptotagmin-9 Regulates Early Phase Insulin Secretion by Regulating Tomosyn-1

MD MOSTAFIZUR RAHMAN, HAIFA ALSHARIF, SUSHANT BHATNAGAR

Diabetes 2022;71(Supplement_1):314-OR

https://doi.org/10.2337/db22-314-OR

Published: 01 June 2022

View article titled, 314-OR: Synaptotagmin-9 Regulates Early Phase Insulin Secretion by Regulating Tomosyn-1

Meeting Abstracts

1454-P: A Transcriptomic Signature of Pancreatic Islet Leader Beta Cells

PAULINE L. CHABOSSEAU, SU WERN FIONA YONG, LIVIA LOPEZ, ISABELLE LECLERC, YUSUF ALI, AIDA MARTINEZ-SANCHEZ, GUY A. RUTTER

Diabetes 2022;71(Supplement_1):1454-P

https://doi.org/10.2337/db22-1454-P

Published: 01 June 2022

View article titled, 1454-P: A Transcriptomic Signature of Pancreatic Islet Leader Beta Cells

Journal Articles

Cavβ3 Regulates Ca²⁺ Signaling and Insulin Expression in Pancreatic β-Cells in a Cell-Autonomous Manner

Alexander Becker, Barbara Wardas, Houssein Salah, Maryam Amini, Claudia Fecher-Trost, Qiao Sen, Damian Martus, Andreas Beck, Stephan E. Philipp, Veit Flockerzi, Anouar Belkacemi

Diabetes 2021;70(11):2532–2544

https://doi.org/10.2337/db21-0078

Published: 23 August 2021

View article titled, Cavβ3 Regulates Ca2+ Signaling and Insulin Expression in Pancreatic β-Cells in a Cell-Autonomous Manner

Meeting Abstracts

1248-P: Histone Deacetylase Inhibition Improves Store-Operated Calcium Entry and Glucose-Stimulated Insulin Secretion in Cytokine-Stressed Pancreatic ß-Cells

CHIH-CHUN LEE, TATSUYOSHI KONO, STACI A. WEAVER, PAUL SOHN, CARMELLA EVANS-MOLINA

Diabetes 2021;70(Supplement_1):1248-P

https://doi.org/10.2337/db21-1248-P

Published: 01 June 2021

View article titled, 1248-P: Histone Deacetylase Inhibition Improves Store-Operated Calcium Entry and Glucose-Stimulated Insulin Secretion in Cytokine-Stressed Pancreatic ß-Cells

Meeting Abstracts

288-OR: Role of Endoplasmic Reticulum (ER) Calcium in ß-Cell Senescence and Type 1 Diabetes Pathophysiology

STACI A. WEAVER, TATSUYOSHI KONO, FAROOQ SYED, ROBERT N. BONE, CARMELLA EVANS-MOLINA

Diabetes 2021;70(Supplement_1):288-OR

https://doi.org/10.2337/db21-288-OR

Published: 01 June 2021

View article titled, 288-OR: Role of Endoplasmic Reticulum (ER) Calcium in ß-Cell Senescence and Type 1 Diabetes Pathophysiology

Meeting Abstracts

1243-P: The Chd4 Helicase Regulates Pdx1-Controlled Genes Involved in ß-Cell Function

REBECCA K. DAVIDSON, NOLAN CASEY, SUKRATI KANOJIA, JASON SPAETH

Diabetes 2021;70(Supplement_1):1243-P

https://doi.org/10.2337/db21-1243-P

Published: 01 June 2021

View article titled, 1243-P: The Chd4 Helicase Regulates Pdx1-Controlled Genes Involved in ß-Cell Function

Meeting Abstracts

1854-P: Kcnh6 Improves Glucose Metabolism by Inhibiting Oxidative Stress

JING LU, LIN ZHANG, TING-TING SHI

Diabetes 2020;69(Supplement_1):1854-P

https://doi.org/10.2337/db20-1854-P

Published: 01 June 2020

View article titled, 1854-P: Kcnh6 Improves Glucose Metabolism by Inhibiting Oxidative Stress

Meeting Abstracts

1789-P: Inactivation of Acyl-Protein Thioesterase 1, a Major Mediator of Palmitoylation Cycling, Promotes Insulin Secretion and ß-Cell Failure

GUIFANG DONG, XIAOCHAO WEI, LI YIN, CHU FENG, SANGEETA ADAK, ZEENAT A. SHYR, QIANG ZHANG, SHUNTARO MORIKAWA, RIE ASADA, FUMIHIKO URANO, MARIA S. REMEDI, CLAY F. SEMENKOVICH

Diabetes 2020;69(Supplement_1):1789-P

https://doi.org/10.2337/db20-1789-P

Published: 01 June 2020

View article titled, 1789-P: Inactivation of Acyl-Protein Thioesterase 1, a Major Mediator of Palmitoylation Cycling, Promotes Insulin Secretion and ß-Cell Failure

NARROW

Resolving spatiotemporal electrical signaling within the islet via CMOS microelectrode arrays

Electrophysiological Characterization of Inducible Pluripotent Stem Cell–Derived Human β-Like Cells and an SLC30A8 Disease Model

Do We Need a New Hypothesis for K_ATP Closure in β-Cells? Distinguishing the Baby From the Bathwater

The Ailing β-Cell in Diabetes: Insights From a Trip to the ER: The 2023 Outstanding Scientific Achievement Award Lecture

Protease-Activated Receptor 1–Mediated Damage of Podocytes in Diabetic Nephropathy

1512-P: The Novel Roles of Intracellular Calcium and Phosphoinositides in Insulin Signaling and Metabolic Disease

1777-P: Three-Dimensional Imaging Reveals Pancreatic Islet Fast Calcium Wave Origin Formation

1650-P: Characterizing the Mechanism of Action of the Lipokine 12,13-diHOME

1558-P: The Mitochondrial Calcium Uniporter Regulates Hepatic Mitochondrial Oxidation and Intracellular Redox In Vivo

1767-P: “Leader” ß-Cells within the Pancreatic Islet Are a Functionally Stable Subpopulation In Vitro and In Vivo

219-LB: The Mitochondrial Calcium Uniporter Regulates Hepatic Lipid Accumulation and Mitochondrial Oxidation

1487-PUB: Fostering the Health Literacy of Younger Generations

314-OR: Synaptotagmin-9 Regulates Early Phase Insulin Secretion by Regulating Tomosyn-1

1454-P: A Transcriptomic Signature of Pancreatic Islet Leader Beta Cells

Cavβ3 Regulates Ca²⁺ Signaling and Insulin Expression in Pancreatic β-Cells in a Cell-Autonomous Manner

1248-P: Histone Deacetylase Inhibition Improves Store-Operated Calcium Entry and Glucose-Stimulated Insulin Secretion in Cytokine-Stressed Pancreatic ß-Cells

288-OR: Role of Endoplasmic Reticulum (ER) Calcium in ß-Cell Senescence and Type 1 Diabetes Pathophysiology

1243-P: The Chd4 Helicase Regulates Pdx1-Controlled Genes Involved in ß-Cell Function

1854-P: Kcnh6 Improves Glucose Metabolism by Inhibiting Oxidative Stress

1789-P: Inactivation of Acyl-Protein Thioesterase 1, a Major Mediator of Palmitoylation Cycling, Promotes Insulin Secretion and ß-Cell Failure

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