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Journal Articles

Placing a Hex on Glucose Uptake

Faith M. Bowman, Scott A. Summers, William L. Holland

Diabetes 2023;72(6):690–692

DOI: https://doi.org/10.2337/dbi22-0040

Published: 19 May 2023

View article titled, Placing a Hex on Glucose Uptake

Meeting Abstracts

370-OR: Proinflammatory Stress Activates Neutral Sphingomyelinase 2 Based Generation of Ceramide-Enriched ß-Cell Exosomes

JERRY XU, EMILY K. SIMS

Diabetes 2022;71(Supplement_1):370-OR

DOI: https://doi.org/10.2337/db22-370-OR

Published: 01 June 2022

View article titled, 370-OR: Proinflammatory Stress Activates Neutral Sphingomyelinase 2 Based Generation of Ceramide-Enriched ß-Cell Exosomes

Meeting Abstracts

164-LB: Association of Ceramide and Sphingolipid Species with Incident Prediabetes among Offspring of Parents with Type 2 Diabetes

NAWAJES MANDAL, JIM Y. WAN, FRANKIE B. STENTZ, SAMUEL DAGOGO-JACK

Diabetes 2022;71(Supplement_1):164-LB

DOI: https://doi.org/10.2337/db22-164-LB

Published: 01 June 2022

View article titled, 164-LB: Association of Ceramide and Sphingolipid Species with Incident Prediabetes among Offspring of Parents with Type 2 Diabetes

Meeting Abstracts

209-OR: Ceramide-Based Lipid Profiles and the Prevalence of Type 2 Diabetes Differ between Patients with Coronary Artery Disease and Those with Peripheral Artery Disease

ANDREAS LEIHERER, AXEL MUENDLEIN, EVA MARIA BRANDTNER, CHRISTOPH H. SAELY, ALEXANDER VONBANK, ARTHUR MADER, LUKAS SPRENGER, MAXIMILIAN MAECHLER, BARBARA LARCHER, ANTTI JYLHA, MITJA LAAPERI, REIJO LAAKSONEN, WINFRIED MAERZ, PETER FRAUNBERGER, MARCUS KLEBER, HEINZ DREXEL

Diabetes 2022;71(Supplement_1):209-OR

DOI: https://doi.org/10.2337/db22-209-OR

Published: 01 June 2022

View article titled, 209-OR: Ceramide-Based Lipid Profiles and the Prevalence of Type 2 Diabetes Differ between Patients with Coronary Artery Disease and Those with Peripheral Artery Disease

Meeting Abstracts

12-OR: Preventing ß-Cell Death under Glucotoxic Conditions: The Role of ChREBPb

LIORA S. KATZ, GABRIEL BRILL, MARK A. HERMAN, ADOLFO GARCIA-OCANA, DONALD SCOTT

Diabetes 2022;71(Supplement_1):12-OR

DOI: https://doi.org/10.2337/db22-12-OR

Published: 01 June 2022

View article titled, 12-OR: Preventing ß-Cell Death under Glucotoxic Conditions: The Role of ChREBPb

Meeting Abstracts

1349-P: Bariatric Surgery Causes an Early Improvement in the Lipidomic Profile and a Decrease in Plasma Ceramides and Diacylglycerols in Patients with Type 2 Diabetes and NAFLD

SRILAXMI KALAVALAPALLI, DIANA BARB, RACHEL E. DILLARD, EDDISON GODINEZ, JEFFREY FRIEDMAN, NADA FANOUS, CURTIS O. WARREN, FERNANDO BRIL, ROMINA LOMONACO, ALI ZARRINPAR, KENNETH CUSI

Diabetes 2022;71(Supplement_1):1349-P

DOI: https://doi.org/10.2337/db22-1349-P

Published: 01 June 2022

View article titled, 1349-P: Bariatric Surgery Causes an Early Improvement in the Lipidomic Profile and a Decrease in Plasma Ceramides and Diacylglycerols in Patients with Type 2 Diabetes and NAFLD

Journal Articles

Surplus Ceramides: An Added Twist in the Tale of TREM2 and Insulin Resistance

Kierstin L. Webster, Lev Becker

Diabetes 2021;70(9):1926–1928

DOI: https://doi.org/10.2337/dbi21-0017

Published: 07 September 2021

View article titled, Surplus Ceramides: An Added Twist in the Tale of TREM2 and Insulin Resistance

Meeting Abstracts

363-P: The Ceramide- and Phosphatidylcholine-Based Coronary Event Risk Test 2 (CERT2) and Cardiovascular Mortality in Men and Women with Type 2 Diabetes

ANDREAS LEIHERER, AXEL MUENDLEIN, CHRISTOPH H. SAELY, BARBARA LARCHER, ARTHUR MADER, MAXIMILIAN MAECHLER, LUKAS SPRENGER, BEATRIX MUTSCHLECHNER, REIJO LAAKSONEN, MITJA LAAPERI, ANTTI JYLHA, PETER FRAUNBERGER, HEINZ DREXEL

Diabetes 2021;70(Supplement_1):363-P

DOI: https://doi.org/10.2337/db21-363-P

Published: 01 June 2021

View article titled, 363-P: The Ceramide- and Phosphatidylcholine-Based Coronary Event Risk Test 2 (CERT2) and Cardiovascular Mortality in Men and Women with Type 2 Diabetes

Meeting Abstracts

39-OR: Pancreatic Beta Cell SERCA2 Deficiency Impacts ER-Golgi Vesicle Trafficking and Ceramide Metabolism

TATSUYOSHI KONO, HITOSHI IIDA, CHIH-CHUN LEE, PREETHI KRISHNAN, PETER ARVAN, IRIS LINDBERG, CARMELLA EVANS-MOLINA

Diabetes 2021;70(Supplement_1):39-OR

DOI: https://doi.org/10.2337/db21-39-OR

Published: 01 June 2021

View article titled, 39-OR: Pancreatic Beta Cell SERCA2 Deficiency Impacts ER-Golgi Vesicle Trafficking and Ceramide Metabolism

Meeting Abstracts

120-OR: Dapagliflozin Increases Adiponectin and Its Receptors, and Reduces Inflammation and Ceramide Synthesis Enzymes in the Obese Prediabetic Dog

MORVARID KABIR, RICHARD N. BERGMAN, V. SASHI GOPAUL, HSIUCHIUNG YANG, CATHRYN M. KOLKA

Diabetes 2021;70(Supplement_1):120-OR

DOI: https://doi.org/10.2337/db21-120-OR

Published: 01 June 2021

View article titled, 120-OR: Dapagliflozin Increases Adiponectin and Its Receptors, and Reduces Inflammation and Ceramide Synthesis Enzymes in the Obese Prediabetic Dog

Journal Articles

Beneficial Metabolic Effects of TREM2 in Obesity Are Uncoupled From Its Expression on Macrophages

Diabetes 2021;70(9):2042–2057

DOI: https://doi.org/10.2337/db20-0572

Published: 24 February 2021

View article titled, Beneficial Metabolic Effects of TREM2 in Obesity Are Uncoupled From Its Expression on Macrophages

Journal Articles

A Novel Model of Diabetic Complications: Adipocyte Mitochondrial Dysfunction Triggers Massive β-Cell Hyperplasia

Christine M. Kusminski, Alexandra L. Ghaben, Thomas S. Morley, Ricardo J. Samms, Andrew C. Adams, Yu An, Joshua A. Johnson, Nolwenn Joffin, Toshiharu Onodera, Clair Crewe, William L. Holland, Ruth Gordillo, Philipp E. Scherer

Diabetes 2020;69(3):313–330

DOI: https://doi.org/10.2337/db19-0327

Published: 27 December 2020

View article titled, A Novel Model of Diabetic Complications: Adipocyte Mitochondrial Dysfunction Triggers Massive β-Cell Hyperplasia

Includes: Supplementary data

Meeting Abstracts

7-OR: Comparison of Two Recent Ceramide-Based Coronary Risk Prediction Scores: CERT and CERT-2

ANDREAS LEIHERER, AXEL MUENDLEIN, CHRISTOPH H. SAELY, REIJO LAAKSONEN, MITJA LAAPERI, ALEXANDER VONBANK, PETER FRAUNBERGER, HEINZ DREXEL

Diabetes 2020;69(Supplement_1):7-OR

DOI: https://doi.org/10.2337/db20-7-OR

Published: 01 June 2020

View article titled, 7-OR: Comparison of Two Recent Ceramide-Based Coronary Risk Prediction Scores: CERT and CERT-2

Meeting Abstracts

200-LB: Ceramide Kinase CERK Regulates Inflammatory Responses in Monocytes/Macrophages Induced by TNF-a

FATEMA ALRASHED, RASHEED AHMAD

Diabetes 2020;69(Supplement_1):200-LB

DOI: https://doi.org/10.2337/db20-200-LB

Published: 01 June 2020

View article titled, 200-LB: Ceramide Kinase CERK Regulates Inflammatory Responses in Monocytes/Macrophages Induced by TNF-a

Journal Articles

Disturbed Fatty Acid Oxidation, Endoplasmic Reticulum Stress, and Apoptosis in Left Ventricle of Patients With Type 2 Diabetes

Marko Ljubkovic, Melanie Gressette, Cristijan Bulat, Marija Cavar, Darija Bakovic, Damir Fabijanic, Ivica Grkovic, Christophe Lemaire, Jasna Marinovic

Diabetes 2019;68(10):1924–1933

DOI: https://doi.org/10.2337/db19-0423

Published: 07 August 2019

View article titled, Disturbed Fatty Acid Oxidation, Endoplasmic Reticulum Stress, and Apoptosis in Left Ventricle of Patients With Type 2 Diabetes

Includes: Supplementary data

Meeting Abstracts

583-P: Increase in Mitochondrial Ceramide Contributes to Diabetes-Induced Retinal Endothelial Cell Damage

DAVID PEGOUSKE, YAN LEVITSKY, SANDRA HAMMER, TODD A. LYDIC, ARTEM MUCHNIK, DENIS A. PROSHLYAKOV, JULIA V. BUSIK

Diabetes 2019;68(Supplement_1):583-P

DOI: https://doi.org/10.2337/db19-583-P

Published: 01 June 2019

View article titled, 583-P: Increase in Mitochondrial Ceramide Contributes to Diabetes-Induced Retinal Endothelial Cell Damage

Meeting Abstracts

1775-P: Impact of Acetyl-CoA Carboxylase 2 Inhibition on Skeletal Muscle Diacylglycerol and Ceramide Levels and Its Potential Contribution to Improved Glucose Metabolism

HIROYUKI TAKAGI, TATSUYA IKEHARA, KUMI HASHIMOTO, ATSUYUKI SHIMAZAKI, YUTO KASHIWAGI, YUJI NISHIURA, MITSURU NOTOYA, HIDEO YUKIOKA

Diabetes 2019;68(Supplement_1):1775-P

DOI: https://doi.org/10.2337/db19-1775-P

Published: 01 June 2019

View article titled, 1775-P: Impact of Acetyl-CoA Carboxylase 2 Inhibition on Skeletal Muscle Diacylglycerol and Ceramide Levels and Its Potential Contribution to Improved Glucose Metabolism

Meeting Abstracts

433-P: Serum Ceramides and Type 2 Diabetes Are Mutually Independent Predictors of Cardiovascular Events in Patients with Peripheral Artery Disease

ANDREAS LEIHERER, AXEL MUENDLEIN, CHRISTOPH H. SAELY, REJO LAAKSONEN, MITJA LAAPERI, ALEXANDER VONBANK, BARBARA LARCHER, ARTHUR MADER, PETER FRAUNBERGER, IRIS BAUMGARTNER, HEINZ DREXEL, JÖRN F. DOPHEIDE

Diabetes 2019;68(Supplement_1):433-P

DOI: https://doi.org/10.2337/db19-433-P

Published: 01 June 2019

View article titled, 433-P: Serum Ceramides and Type 2 Diabetes Are Mutually Independent Predictors of Cardiovascular Events in Patients with Peripheral Artery Disease

Meeting Abstracts

1900-P: Very Low-Density Lipoprotein Ceramides and Hepatic Lipid Accumulation

JUSTINE M. MUCINSKI

Diabetes 2019;68(Supplement_1):1900-P

DOI: https://doi.org/10.2337/db19-1900-P

Published: 01 June 2019

View article titled, 1900-P: Very Low-Density Lipoprotein Ceramides and Hepatic Lipid Accumulation

Meeting Abstracts

417-P: Serum Ceramide Ratios Predict Cardiovascular Events in Patients with Type 2 Diabetes Independently from the Presence of Coronary Artery Disease

ANDREAS LEIHERER, AXEL MUENDLEIN, CHRISTOPH H. SAELY, REJO LAAKSONEN, MITJA LAAPERI, ALEXANDER VONBANK, BARBARA LARCHER, ARTHUR MADER, PETER FRAUNBERGER, HEINZ DREXEL

Diabetes 2019;68(Supplement_1):417-P

DOI: https://doi.org/10.2337/db19-417-P

Published: 01 June 2019

View article titled, 417-P: Serum Ceramide Ratios Predict Cardiovascular Events in Patients with Type 2 Diabetes Independently from the Presence of Coronary Artery Disease

NARROW

Placing a Hex on Glucose Uptake

370-OR: Proinflammatory Stress Activates Neutral Sphingomyelinase 2 Based Generation of Ceramide-Enriched ß-Cell Exosomes

164-LB: Association of Ceramide and Sphingolipid Species with Incident Prediabetes among Offspring of Parents with Type 2 Diabetes

209-OR: Ceramide-Based Lipid Profiles and the Prevalence of Type 2 Diabetes Differ between Patients with Coronary Artery Disease and Those with Peripheral Artery Disease

12-OR: Preventing ß-Cell Death under Glucotoxic Conditions: The Role of ChREBPb

1349-P: Bariatric Surgery Causes an Early Improvement in the Lipidomic Profile and a Decrease in Plasma Ceramides and Diacylglycerols in Patients with Type 2 Diabetes and NAFLD

Surplus Ceramides: An Added Twist in the Tale of TREM2 and Insulin Resistance

363-P: The Ceramide- and Phosphatidylcholine-Based Coronary Event Risk Test 2 (CERT2) and Cardiovascular Mortality in Men and Women with Type 2 Diabetes

39-OR: Pancreatic Beta Cell SERCA2 Deficiency Impacts ER-Golgi Vesicle Trafficking and Ceramide Metabolism

120-OR: Dapagliflozin Increases Adiponectin and Its Receptors, and Reduces Inflammation and Ceramide Synthesis Enzymes in the Obese Prediabetic Dog

Beneficial Metabolic Effects of TREM2 in Obesity Are Uncoupled From Its Expression on Macrophages

A Novel Model of Diabetic Complications: Adipocyte Mitochondrial Dysfunction Triggers Massive β-Cell Hyperplasia

7-OR: Comparison of Two Recent Ceramide-Based Coronary Risk Prediction Scores: CERT and CERT-2

200-LB: Ceramide Kinase CERK Regulates Inflammatory Responses in Monocytes/Macrophages Induced by TNF-a

Disturbed Fatty Acid Oxidation, Endoplasmic Reticulum Stress, and Apoptosis in Left Ventricle of Patients With Type 2 Diabetes

583-P: Increase in Mitochondrial Ceramide Contributes to Diabetes-Induced Retinal Endothelial Cell Damage

1775-P: Impact of Acetyl-CoA Carboxylase 2 Inhibition on Skeletal Muscle Diacylglycerol and Ceramide Levels and Its Potential Contribution to Improved Glucose Metabolism

433-P: Serum Ceramides and Type 2 Diabetes Are Mutually Independent Predictors of Cardiovascular Events in Patients with Peripheral Artery Disease

1900-P: Very Low-Density Lipoprotein Ceramides and Hepatic Lipid Accumulation

417-P: Serum Ceramide Ratios Predict Cardiovascular Events in Patients with Type 2 Diabetes Independently from the Presence of Coronary Artery Disease

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