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Journal Articles

Long-term Nerve Regeneration in Diabetic Keratopathy Mediated by a Novel NGF Delivery System

Lin Cong, Benxiang Qi, Shijiu Chen, Ruiling Liu, Suxia Li, Qingjun Zhou, Yihai Cao, Bi Ning Zhang, Lixin Xie
Journal: Diabetes
Diabetes 2024;74(1):22–35
https://doi.org/10.2337/db24-0393
Published: 24 October 2024
View article titled, Long-term Nerve Regeneration in Diabetic Keratopathy Mediated by a Novel NGF Delivery System
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Meeting Abstracts

491-P: Corneal Nerve Sensitivity—Early Detection of Diabetic Peripheral Neuropathy (DPN)

MARK A. YOREK, MARCELO CORREIA, RANDY KARDON, PIETER POOLMAN
Journal: Diabetes
Diabetes 2023;72(Supplement_1):491-P
https://doi.org/10.2337/db23-491-P
Published: 20 June 2023
View article titled, 491-P: Corneal Nerve Sensitivity—Early Detection of Diabetic Peripheral Neuropathy (DPN)
Meeting Abstracts

486-P: Reduced Serum Netrin-1 Levels Correlate with Corneal Nerve Fiber Loss in Diabetic Neuropathy

ASIF MONDAL, CHIRANJIT BOSE, SUBHASISH PRAMANIK, AYAN MUKHERJEE, BIDISHA MUKHERJEE, SATINATH MUKHOPADHYAY
Journal: Diabetes
Diabetes 2023;72(Supplement_1):486-P
https://doi.org/10.2337/db23-486-P
Published: 20 June 2023
View article titled, 486-P: Reduced Serum Netrin-1 Levels Correlate with Corneal Nerve Fiber Loss in Diabetic Neuropathy
Journal Articles

Fenofibrate for Treating Diabetic Eye Disease

Rafael Simó, Cristina Hernández
Journal: Diabetes
Diabetes 2023;72(7):838–840
https://doi.org/10.2337/dbi22-0037
Published: 20 June 2023
View article titled, Fenofibrate for Treating Diabetic Eye Disease
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Journal Articles

In This Issue of Diabetes

Max Bingham, PhD
Journal: Diabetes
Diabetes 2023;72(7):823–824
https://doi.org/10.2337/db23-ti07
Published: 20 June 2023
View article titled, In This Issue of <em>Diabetes</em>
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Journal Articles

Comparison of Novel Wide-Field In Vivo Corneal Confocal Microscopy With Skin Biopsy for Assessing Peripheral Neuropathy in Type 2 Diabetes

Reza A. Badian, Linnéa Ekman, Are Hugo Pripp, Tor Paaske Utheim, Elisabet Englund, Lars B. Dahlin, Olov Rolandsson, Neil Lagali
Journal: Diabetes
Diabetes 2023;72(7):908–917
https://doi.org/10.2337/db22-0863
Published: 14 April 2023
View article titled, Comparison of Novel Wide-Field In Vivo Corneal Confocal Microscopy With Skin Biopsy for Assessing Peripheral Neuropathy in Type 2 Diabetes
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Journal Articles

Oral Peroxisome Proliferator–Activated Receptor-α Agonist Enhances Corneal Nerve Regeneration in Patients With Type 2 Diabetes

Calesta Hui Yi Teo, Molly Tzu-Yu Lin, Isabelle Xin Yu Lee, Siew-Kwan Koh, Lei Zhou, Dylan Shaoying Goh, Hyungwon Choi, Hiromi Wai Ling Koh, Amanda Yun Rui Lam, Paik Shia Lim, Jodhbir S. Mehta, Jean-Paul Kovalik, Thomas M. Coffman, Hong Chang Tan, Yu-Chi Liu
Journal: Diabetes
Diabetes 2023;72(7):932–946
https://doi.org/10.2337/db22-0611
Published: 29 November 2022
View article titled, Oral Peroxisome Proliferator–Activated Receptor-α Agonist Enhances Corneal Nerve Regeneration in Patients With Type 2 Diabetes
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Journal Articles

Pathogenic Role of Diabetes-Induced Overexpression of Kallistatin in Corneal Wound Healing Deficiency Through Inhibition of Canonical Wnt Signaling

Wentao Liang, Li Huang, Xiang Ma, Lijie Dong, Rui Cheng, Marcus Dehdarani, Dimitrios Karamichos, Jian-xing Ma
Journal: Diabetes
Diabetes 2022;71(4):747–761
https://doi.org/10.2337/db21-0740
Published: 19 January 2022
View article titled, Pathogenic Role of Diabetes-Induced Overexpression of Kallistatin in Corneal Wound Healing Deficiency Through Inhibition of Canonical Wnt Signaling
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Journal Articles

Investigating the Neuroprotective Effect of Oral Omega-3 Fatty Acid Supplementation in Type 1 Diabetes (nPROOFS1): A Randomized Placebo-Controlled Trial

Alexis Ceecee Britten-Jones, Jordan T. Kamel, Leslie J. Roberts, Sabine Braat, Jennifer P. Craig, Richard J. MacIsaac, Laura E. Downie
Journal: Diabetes
Diabetes 2021;70(8):1794–1806
https://doi.org/10.2337/db21-0136
Published: 05 May 2021
View article titled, Investigating the Neuroprotective Effect of Oral Omega-3 Fatty Acid Supplementation in Type 1 Diabetes (nPROOFS1): A Randomized Placebo-Controlled Trial
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Meeting Abstracts

571-P: A Cross-Sectional Observational Study on Correlation between the Central Corneal Thickness and Diabetic Retinopathy

ARJUN BAIDYA, QUAZI SHEHNAZ WAHEED, AJOY DEY SARKAR
Journal: Diabetes
Diabetes 2020;69(Supplement_1):571-P
https://doi.org/10.2337/db20-571-P
Published: 01 June 2020
View article titled, 571-P: A Cross-Sectional Observational Study on Correlation between the Central Corneal Thickness and Diabetic Retinopathy
Meeting Abstracts

124-OR: Progressive Loss of Corneal Nerve Fibers and Sensitivity with Duration of Obesity Type 2 Diabetes in Sprague-Dawley Rats: Valid Marker for Peripheral Neuropathy and Treatment

MARK A. YOREK
Journal: Diabetes
Diabetes 2020;69(Supplement_1):124-OR
https://doi.org/10.2337/db20-124-OR
Published: 01 June 2020
View article titled, 124-OR: Progressive Loss of Corneal Nerve Fibers and Sensitivity with Duration of Obesity Type 2 Diabetes in Sprague-Dawley Rats: Valid Marker for Peripheral Neuropathy and Treatment
Journal Articles

Role of VIP and Sonic Hedgehog Signaling Pathways in Mediating Epithelial Wound Healing, Sensory Nerve Regeneration, and Their Defects in Diabetic Corneas

Yangyang Zhang, Nan Gao, Lin Wu, Patrick S.Y. Lee, Rao Me, Chenyang Dai, Lixin Xie, Fu-shin X. Yu
Journal: Diabetes
Diabetes 2020;69(7):1549–1561
https://doi.org/10.2337/db19-0870
Published: 28 April 2020
View article titled, Role of VIP and Sonic Hedgehog Signaling Pathways in Mediating Epithelial Wound Healing, Sensory Nerve Regeneration, and Their Defects in Diabetic Corneas
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Journal Articles

MANF Promotes Diabetic Corneal Epithelial Wound Healing and Nerve Regeneration by Attenuating Hyperglycemia-Induced Endoplasmic Reticulum Stress

Xiaochuan Wang, Weina Li, Qingjun Zhou, Jing Li, Xiaolei Wang, Jing Zhang, Dewei Li, Xia Qi, Ting Liu, Xiaowen Zhao, Suxia Li, Lingling Yang, Lixin Xie
Journal: Diabetes
Diabetes 2020;69(6):1264–1278
https://doi.org/10.2337/db19-0835
Published: 20 April 2020
View article titled, MANF Promotes Diabetic Corneal Epithelial Wound Healing and Nerve Regeneration by Attenuating Hyperglycemia-Induced Endoplasmic Reticulum Stress
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Journal Articles

Pathogenic Role of PPARα Downregulation in Corneal Nerve Degeneration and Impaired Corneal Sensitivity in Diabetes

H. Greg Matlock, Fangfang Qiu, Volha Malechka, Kelu Zhou, Rui Cheng, Siribhinya Benyajati, Amy Whelchel, Dimitrios Karamichos, Jian-xing Ma
Journal: Diabetes
Diabetes 2020;69(6):1279–1291
https://doi.org/10.2337/db19-0898
Published: 25 March 2020
View article titled, Pathogenic Role of PPARα Downregulation in Corneal Nerve Degeneration and Impaired Corneal Sensitivity in Diabetes
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Journal Articles

Effects of Vitamin D Receptor Knockout and Vitamin D Deficiency on Corneal Epithelial Wound Healing and Nerve Density in Diabetic Mice

Xiaowen Lu, Sarah Vick, Zhong Chen, Jie Chen, Mitchell A. Watsky
Journal: Diabetes
Diabetes 2020;69(5):1042–1051
https://doi.org/10.2337/db19-1051
Published: 05 March 2020
View article titled, Effects of Vitamin D Receptor Knockout and Vitamin D Deficiency on Corneal Epithelial Wound Healing and Nerve Density in Diabetic Mice
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Journal Articles

Amelioration of Both Central and Peripheral Neuropathy in Mouse Models of Type 1 and Type 2 Diabetes by the Neurogenic Molecule NSI-189

Corinne G. Jolivalt, Alexandra Marquez, David Quach, Michelle C. Navarro Diaz, Carlos Anaya, Betelhem Kifle, Nabeel Muttalib, Gabriela Sanchez, Lucy Guernsey, Mike Hefferan, Darrel R. Smith, Paul Fernyhough, Karl Johe, Nigel A. Calcutt
Journal: Diabetes
Diabetes 2019;68(11):2143–2154
https://doi.org/10.2337/db19-0271
Published: 06 September 2019
View article titled, Amelioration of Both Central and Peripheral Neuropathy in Mouse Models of Type 1 and Type 2 Diabetes by the Neurogenic Molecule NSI-189
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Includes: Supplementary data
Meeting Abstracts

324-OR: Rapid Corneal Nerve Fibre Loss Predicts Neuropathy Progression in Diabetes: A Longitudinal Multinational Consortium Study

EVAN J.H. LEWIS, LEIF ERIK LOVBLOM, MARYAM FERDOUSI, MARIA JEZIORSKA, DANIÈLE PACAUD, NICOLA PRITCHARD, RONI M. SHTEIN, NATHAN EFRON, MITRA TAVAKOLI, VERA BRIL, RAYAZ A. MALIK, BRUCE A. PERKINS
Journal: Diabetes
Diabetes 2019;68(Supplement_1):324-OR
https://doi.org/10.2337/db19-324-OR
Published: 01 June 2019
View article titled, 324-OR: Rapid Corneal Nerve Fibre Loss Predicts Neuropathy Progression in Diabetes: A Longitudinal Multinational Consortium Study
Meeting Abstracts

323-OR: Prediction of Future Neuropathy Onset Using Corneal Confocal Microscopy: A Longitudinal Multinational Consortium Study

BRUCE A. PERKINS, LEIF ERIK LOVBLOM, VERA BRIL, MARYAM FERDOUSI, ANDREJ ORSZAG, KATIE EDWARDS, NICOLA PRITCHARD, ANTHONY W. RUSSELL, CIROUS DEHGHANI, DANIÈLE PACAUD, KENNETH ROMANCHUK, JEAN MAH, MARIA JEZIORSKA, ANDREW MARSHALL, RONI M. SHTEIN, RODICA POP-BUSUI, STEPHEN I. LENTZ, ANDREW J. BOULTON, MITRA TAVAKOLI, NATHAN EFRON, RAYAZ A. MALIK
Journal: Diabetes
Diabetes 2019;68(Supplement_1):323-OR
https://doi.org/10.2337/db19-323-OR
Published: 01 June 2019
View article titled, 323-OR: Prediction of Future Neuropathy Onset Using Corneal Confocal Microscopy: A Longitudinal Multinational Consortium Study
Journal Articles

Opposing Effects of Neuropilin-1 and -2 on Sensory Nerve Regeneration in Wounded Corneas: Role of Sema3C in Ameliorating Diabetic Neurotrophic Keratopathy

Patrick Shean-Young Lee, Nan Gao, Mamata Dike, Olga Shkilnyy, Rao Me, Yangyang Zhang, Fu-Shin X. Yu
Journal: Diabetes
Diabetes 2019;68(4):807–818
https://doi.org/10.2337/db18-1172
Published: 24 January 2019
View article titled, Opposing Effects of Neuropilin-1 and -2 on Sensory Nerve Regeneration in Wounded Corneas: Role of Sema3C in Ameliorating Diabetic Neurotrophic Keratopathy
Open the PDF for Opposing Effects of Neuropilin-1 and -2 on Sensory Nerve Regeneration in Wounded Corneas: Role of Sema3C in Ameliorating Diabetic Neurotrophic Keratopathy in another window
Includes: Supplementary data
Meeting Abstracts

The Reference Distribution of Annual Change in Corneal Nerve Fibre Length in Diabetes Mellitus

EVAN J.H. LEWIS, MITRA TAVAKOLI, LEIF ERIK LOVBLOM, ELISE M. HALPERN, MARIA JEZIORSKA, DANIÈLE PACAUD, NICOLA PRITCHARD, RONI M. SHTEIN, NATHAN EFRON, VERA BRIL, RAYAZ A. MALIK, BRUCE A. PERKINS
Journal: Diabetes
Diabetes 2018;67(Supplement_1):580-P
https://doi.org/10.2337/db18-580-P
Published: 01 July 2018
View article titled, The Reference Distribution of Annual Change in Corneal Nerve Fibre Length in Diabetes Mellitus