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Journal Articles

Cystic Fibrosis–Related Diabetes Workshop: Research Priorities Spanning Disease Pathophysiology, Diagnosis, and Outcomes

Melissa S. Putman, Andrew W. Norris, Rebecca L. Hull, Michael R. Rickels, Lori Sussel, Scott M. Blackman, Christine L. Chan, Katie Larson Ode, Tanicia Daley, Arlene A. Stecenko, Antoinette Moran, Meagan J. Helmick, Sharon Cray, Jessica A. Alvarez, Virginia A. Stallings, Katherine L. Tuggle, John P. Clancy, Thomas L. Eggerman, John F. Engelhardt, Andrea Kelly
Journal: Diabetes
Diabetes 2023;72(6):677–689
DOI: https://doi.org/10.2337/db22-0949
Published: 01 May 2023
View article titled, Cystic Fibrosis–Related Diabetes Workshop: Research Priorities Spanning Disease Pathophysiology, Diagnosis, and Outcomes
Click here to open pdf in another window PDF for Cystic Fibrosis–Related Diabetes Workshop: Research Priorities Spanning Disease Pathophysiology, Diagnosis, and Outcomes
Journal Articles

Integrated Physiology of the Exocrine and Endocrine Compartments in Pancreatic Diseases: Workshop Proceedings

Teresa L. Mastracci, Minoti Apte, Laufey T. Amundadottir, Alexandra Alvarsson, Steven Artandi, Melena D. Bellin, Ernesto Bernal-Mizrachi, Alejandro Caicedo, Martha Campbell-Thompson, Zobeida Cruz-Monserrate, Abdelfattah El Ouaamari, Kyle J. Gaulton, Andrea Geisz, Mark O. Goodarzi, Manami Hara, Rebecca L. Hull-Meichle, Alexander Kleger, Alison P. Klein, Janel L. Kopp, Rohit N. Kulkarni, Mandar D. Muzumdar, Anjaparavanda P. Naren, Scott A. Oakes, Søren S. Olesen, Edward A. Phelps, Alvin C. Powers, Cherie L. Stabler, Temel Tirkes, David C. Whitcomb, Dhiraj Yadav, Jing Yong, Norann A. Zaghloul, Stephen J. Pandol, Maike Sander
Journal: Diabetes
Diabetes 2023;72(4):433–448
DOI: https://doi.org/10.2337/db22-0942
Published: 20 March 2023
View article titled, Integrated Physiology of the Exocrine and Endocrine Compartments in Pancreatic Diseases: Workshop Proceedings
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Journal Articles

Effects of GLP-1 and GIP on Islet Function in Glucose-Intolerant, Pancreatic-Insufficient Cystic Fibrosis

Sarah C. Nyirjesy, Amy J. Peleckis, Jack N. Eiel, Kathryn Gallagher, Andriana Doliba, Abigail Tami, Anneliese J. Flatt, Diva D. De Leon, Denis Hadjiliadis, Saba Sheikh, Darko Stefanovski, Robert Gallop, David A. D’Alessio, Ronald C. Rubenstein, Andrea Kelly, Michael R. Rickels
Journal: Diabetes
Diabetes 2022;71(10):2153–2165
DOI: https://doi.org/10.2337/db22-0399
Published: 07 July 2022
View article titled, Effects of GLP-1 and GIP on Islet Function in Glucose-Intolerant, Pancreatic-Insufficient Cystic Fibrosis
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Meeting Abstracts

1451-P: Peri-Islet Fibrosis in Cystic Fibrosis Is Associated with Altered Alpha-Cell Phenotype

NICOLE KATTNER, YARA AL-SELWI, DINA TINIAKOS, GÜNTER KLÖPPEL, JAMES A. SHAW
Journal: Diabetes
Diabetes 2022;71(Supplement_1):1451-P
DOI: https://doi.org/10.2337/db22-1451-P
Published: 01 June 2022
View article titled, 1451-P: Peri-Islet Fibrosis in Cystic Fibrosis Is Associated with Altered Alpha-Cell Phenotype
Meeting Abstracts

13-OR: Cystic Fibrosis Donors Exhibit Striking Decrease in Pancreatic Islet and Exocrine Capillaries

JOSEPH J. CASTILLO, ALFRED APLIN, REHANA AKTER, REBECCA L. HULL-MEICHLE
Journal: Diabetes
Diabetes 2022;71(Supplement_1):13-OR
DOI: https://doi.org/10.2337/db22-13-OR
Published: 01 June 2022
View article titled, 13-OR: Cystic Fibrosis Donors Exhibit Striking Decrease in Pancreatic Islet and Exocrine Capillaries
Meeting Abstracts

828-P: Preservation of ß-Cell Function in Pancreatic Insufficient Cystic Fibrosis (CF) with Highly Effective CFTR Modulator Therapy

ANNELIESE FLATT, SABA SHEIKH, AMY J. PELECKIS, KATHRYN GALLAGHER, PAOLA ALVARADO, DENIS HADJILIADIS, DARKO STEFANOVSKI, ROBERT J. GALLOP, RONALD C. RUBENSTEIN, MICHAEL R. RICKELS, ANDREA KELLY
Journal: Diabetes
Diabetes 2022;71(Supplement_1):828-P
DOI: https://doi.org/10.2337/db22-828-P
Published: 01 June 2022
View article titled, 828-P: Preservation of ß-Cell Function in Pancreatic Insufficient Cystic Fibrosis (CF) with Highly Effective CFTR Modulator Therapy
Meeting Abstracts

769-P: Effect on Insulin Secretion Six Months after the Use of CFTR Modulators in Cystic Fibrosis Patients with or without Glucose Metabolism Abnormalities

EDURNE LECUMBERRI, SAIOA VICENTE, MARIA MARTIN-FRIAS, LÍA NATTERO-CHÁVEZ, VICTORIA MARTÍNEZ-VAELLO, LUIS MAIZ, CRISTINA SÁNCHEZ RODRÍGUEZ, MAR LORENZO, BEATRIZ DORADO AVENDAÑO, ROSA Y. YELMO, MARÍA GARRIGA, ADELAIDA F. LAMAS
Journal: Diabetes
Diabetes 2021;70(Supplement_1):769-P
DOI: https://doi.org/10.2337/db21-769-P
Published: 01 June 2021
View article titled, 769-P: Effect on Insulin Secretion Six Months after the Use of CFTR Modulators in Cystic Fibrosis Patients with or without Glucose Metabolism Abnormalities
Meeting Abstracts

1783-P: Effects of DPP-4 Inhibition on the Enteroinsular Axis in Pancreatic Insufficient Cystic Fibrosis

SABA SHEIKH, ANDREA KELLY, DARKO STEFANOVSKI, AMY J. PELECKIS, SARAH NYIRJESY, JACK N. EIEL, ANIKET SIDHAYE, DIVA D. DE LEON, DENIS HADJILIADIS, RONALD C. RUBENSTEIN, MICHAEL R. RICKELS
Journal: Diabetes
Diabetes 2020;69(Supplement_1):1783-P
DOI: https://doi.org/10.2337/db20-1783-P
Published: 01 June 2020
View article titled, 1783-P: Effects of DPP-4 Inhibition on the Enteroinsular Axis in Pancreatic Insufficient Cystic Fibrosis
Meeting Abstracts

1788-P: Islet Function in Youth with Cystic Fibrosis with and without Liver Disease

MARIA S. RAYAS, KARA S. HUGHAN, RIDA JAVAID, DANIEL LEUNG, DARKO STEFANOVSKI, ANDREA KELLY, MARZIEH SALEHI
Journal: Diabetes
Diabetes 2020;69(Supplement_1):1788-P
DOI: https://doi.org/10.2337/db20-1788-P
Published: 01 June 2020
View article titled, 1788-P: Islet Function in Youth with Cystic Fibrosis with and without Liver Disease
Meeting Abstracts

1842-P: Enhanced TGF-ß1 Signaling in the Ducts of Cystic Fibrosis Pancreas Increases Basal Insulin Secretion by Islets

PAVANA GURURAJ ROTTI, IDIL APAK-EVANS, YUNXIA OMALLEY, ANDREW NORRIS, ALIYE UC, JOHN ENGELHARDT
Journal: Diabetes
Diabetes 2019;68(Supplement_1):1842-P
DOI: https://doi.org/10.2337/db19-1842-P
Published: 01 June 2019
View article titled, 1842-P: Enhanced TGF-ß1 Signaling in the Ducts of Cystic Fibrosis Pancreas Increases Basal Insulin Secretion by Islets
Meeting Abstracts

2326-PUB: The Correction Factor (CF) and Carbohydrate-to-Insulin Ratio (CIR) Are More Correlated to Each Other than to the Total Daily Dose (TDD)

JILLAINE SOCHA, ALLEN B. KING
Journal: Diabetes
Diabetes 2019;68(Supplement_1):2326-PUB
DOI: https://doi.org/10.2337/db19-2326-PUB
Published: 01 June 2019
View article titled, 2326-PUB: The Correction Factor (CF) and Carbohydrate-to-Insulin Ratio (CIR) Are More Correlated to Each Other than to the Total Daily Dose (TDD)
Meeting Abstracts

1500-P: Continuous Glucose Monitoring and Beta-Cell Function in Youth with Cystic Fibrosis

CHRISTINE L. CHAN, TIM B. VIGERS, LAURA PYLE, PHILIP ZEITLER, KRISTEN J. NADEAU
Journal: Diabetes
Diabetes 2019;68(Supplement_1):1500-P
DOI: https://doi.org/10.2337/db19-1500-P
Published: 01 June 2019
View article titled, 1500-P: Continuous Glucose Monitoring and Beta-Cell Function in Youth with Cystic Fibrosis
Meeting Abstracts

223-LB: Beta-Cell Function but Not Insulin Sensitivity Is Impaired in Nondiabetic Cystic Fibrosis Adults Assessed with the Oral Minimal Model Method

MICHELE SCHIAVON, GIANNA MARIA TOFFOLO, CLAUDIO COBELLI, K. SREEKUMARAN NAIR, ANTOINETTE MORAN
Journal: Diabetes
Diabetes 2019;68(Supplement_1):223-LB
DOI: https://doi.org/10.2337/db19-223-LB
Published: 01 June 2019
View article titled, 223-LB: Beta-Cell Function but Not Insulin Sensitivity Is Impaired in Nondiabetic Cystic Fibrosis Adults Assessed with the Oral Minimal Model Method
Meeting Abstracts

Effects of GLP-1 and GIP on Insulin Secretion in Glucose Intolerant, Pancreatic Insufficient Cystic Fibrosis

JACK N. EIEL, SARAH NYIRJESY, AMY J. PELECKIS, DIVA DE LEON, DENIS HADJILIADIS, CHRISTINA KUBRAK, ABIGAIL TAMI, SABA SHEIKH, RONALD C. RUBENSTEIN, ANDREA KELLY, MICHAEL R. RICKELS
Journal: Diabetes
Diabetes 2018;67(Supplement_1):1820-P
DOI: https://doi.org/10.2337/db18-1820-P
Published: 01 July 2018
View article titled, Effects of GLP-1 and GIP on Insulin Secretion in Glucose Intolerant, Pancreatic Insufficient Cystic Fibrosis
Meeting Abstracts

Hemochromatosis and Cystic Fibrosis Carriers Identify Risk for GLP-1 Agonist Associated Pancreatitis

WILLIAM A. WEST, GABRIEL I. UWAIFO
Journal: Diabetes
Diabetes 2018;67(Supplement_1):2296-PUB
DOI: https://doi.org/10.2337/db18-2296-PUB
Published: 01 July 2018
View article titled, Hemochromatosis and Cystic Fibrosis Carriers Identify Risk for GLP-1 Agonist Associated Pancreatitis
Meeting Abstracts

Pediatric Case Series of Cystic Fibrosis and Type 1 Diabetes Autoimmunity

GRACE KIM, LINA MERJANEH
Journal: Diabetes
Diabetes 2018;67(Supplement_1):2341-PUB
DOI: https://doi.org/10.2337/db18-2341-PUB
Published: 01 July 2018
View article titled, Pediatric Case Series of Cystic Fibrosis and Type 1 Diabetes Autoimmunity
Journal Articles

Exocrine and Endocrine Interactions in Cystic Fibrosis: A Potential Key to Understanding Insulin Secretion in Health and Disease?

Claudio Cobelli, Adrian Vella
Journal: Diabetes
Diabetes 2017;66(1):20–22
DOI: https://doi.org/10.2337/dbi16-0049
Published: 10 December 2016
View article titled, Exocrine and Endocrine Interactions in Cystic Fibrosis: A Potential Key to Understanding Insulin Secretion in Health and Disease?
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Journal Articles

Reduced β-Cell Secretory Capacity in Pancreatic-Insufficient, but Not Pancreatic-Sufficient, Cystic Fibrosis Despite Normal Glucose Tolerance

Saba Sheikh, Lalitha Gudipaty, Diva D. De Leon, Denis Hadjiliadis, Christina Kubrak, Nora K. Rosenfeld, Sarah C. Nyirjesy, Amy J. Peleckis, Saloni Malik, Darko Stefanovski, Marina Cuchel, Ronald C. Rubenstein, Andrea Kelly, Michael R. Rickels
Journal: Diabetes
Diabetes 2017;66(1):134–144
DOI: https://doi.org/10.2337/db16-0394
Published: 05 August 2016
View article titled, Reduced β-Cell Secretory Capacity in Pancreatic-Insufficient, but Not Pancreatic-Sufficient, Cystic Fibrosis Despite Normal Glucose Tolerance
Click here to open pdf in another window PDF for Reduced β-Cell Secretory Capacity in Pancreatic-Insufficient, but Not Pancreatic-Sufficient, Cystic Fibrosis Despite Normal Glucose Tolerance
Includes: Supplementary data
Journal Articles

Evidence for a Causal Relationship Between Early Exocrine Pancreatic Disease and Cystic Fibrosis–Related Diabetes: A Mendelian Randomization Study

David Soave, Melissa R. Miller, Katherine Keenan, Weili Li, Jiafen Gong, Wan Ip, Frank Accurso, Lei Sun, Johanna M. Rommens, Marci Sontag, Peter R. Durie, Lisa J. Strug
Journal: Diabetes
Diabetes 2014;63(6):2114–2119
DOI: https://doi.org/10.2337/db13-1464
Published: 15 May 2014
View article titled, Evidence for a Causal Relationship Between Early Exocrine Pancreatic Disease and Cystic Fibrosis–Related Diabetes: A Mendelian Randomization Study
Click here to open pdf in another window PDF for Evidence for a Causal Relationship Between Early Exocrine Pancreatic Disease and Cystic Fibrosis–Related Diabetes: A Mendelian Randomization Study
Journal Articles

Genetic Modifiers of Cystic Fibrosis–Related Diabetes

Scott M. Blackman, Clayton W. Commander, Christopher Watson, Kristin M. Arcara, Lisa J. Strug, Jaclyn R. Stonebraker, Fred A. Wright, Johanna M. Rommens, Lei Sun, Rhonda G. Pace, Sarah A. Norris, Peter R. Durie, Mitchell L. Drumm, Michael R. Knowles, Garry R. Cutting
Journal: Diabetes
Diabetes 2013;62(10):3627–3635
DOI: https://doi.org/10.2337/db13-0510
Published: 17 September 2013
View article titled, Genetic Modifiers of Cystic Fibrosis–Related Diabetes
Click here to open pdf in another window PDF for Genetic Modifiers of Cystic Fibrosis–Related Diabetes
Includes: Supplementary data