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Meeting Abstracts

1809-PUB: Painful Diabetic Neuropathy—Patients Treated with High-Frequency (10 kHz) Spinal Cord Stimulation (SCS) Experience Significant Reductions in A1C and Weight

DAVID C. KLONOFF, BRIAN L. LEVY, MICHAEL JAASMA, MANISH BHARARA, CHRISTIAN E. NASR, DAVID L. CARAWAY, ERIKA PETERSEN, DAVID G. ARMSTRONG

Diabetes 2023;72(Supplement_1):1809-PUB

https://doi.org/10.2337/db23-1809-PUB

Published: 23 June 2023

View article titled, 1809-PUB: Painful Diabetic Neuropathy—Patients Treated with High-Frequency (10 kHz) Spinal Cord Stimulation (SCS) Experience Significant Reductions in A1C and Weight

Meeting Abstracts

482-P: Behavioral Assessment of 10kHz Spinal Cord Stimulation–Mediated Pain Relief in a Rat Model of Painful Diabetic Neuropathy

DONG WANG, DONGCHUL LEE, KWAN LEE, ZACHARY B. KAGAN, KERRY BRADLEY

Diabetes 2023;72(Supplement_1):482-P

https://doi.org/10.2337/db23-482-P

Published: 20 June 2023

View article titled, 482-P: Behavioral Assessment of 10kHz Spinal Cord Stimulation–Mediated Pain Relief in a Rat Model of Painful Diabetic Neuropathy

Meeting Abstracts

481-P: 10kHz SCS Restores Mechanical and Thermal Neural Processing in a Rodent Model of Painful Diabetic Neuropathy

KWAN LEE, DONGCHUL LEE, DONG WANG, ZACHARY B. KAGAN, KERRY BRADLEY

Diabetes 2023;72(Supplement_1):481-P

https://doi.org/10.2337/db23-481-P

Published: 20 June 2023

View article titled, 481-P: 10kHz SCS Restores Mechanical and Thermal Neural Processing in a Rodent Model of Painful Diabetic Neuropathy

Meeting Abstracts

480-P: Synergistic Effects of Hyperglycemia and Dyslipidemia on Diabetic Neuropathy—High Glucose Aggravates Oxidized LDL-Induced Schwann Cell Death via Hyperactivation of TLR4

WATARU NIHEI, AYAKO KATO, TATSUHITO HIMENO, MASAKI KONDO, JIRO NAKAMURA, HIDEKI KAMIYA, KAZUNORI SANGO, KOICHI KATO

Diabetes 2023;72(Supplement_1):480-P

https://doi.org/10.2337/db23-480-P

Published: 20 June 2023

View article titled, 480-P: Synergistic Effects of Hyperglycemia and Dyslipidemia on Diabetic Neuropathy—High Glucose Aggravates Oxidized LDL-Induced Schwann Cell Death via Hyperactivation of TLR4

Meeting Abstracts

104-OR: Identifying Painful Diabetic Neuropathy Subtypes from Resting-State Functional Magnetic Resonance Brain Imaging—A Novel Unsupervised Machine Learning Approach

DINESH SELVARAJAH, KEVIN TEH, APARNA ANANDHANARAYANAN, GORDON P. SLOAN, SOLOMON TESFAYE

Diabetes 2023;72(Supplement_1):104-OR

https://doi.org/10.2337/db23-104-OR

Published: 20 June 2023

View article titled, 104-OR: Identifying Painful Diabetic Neuropathy Subtypes from Resting-State Functional Magnetic Resonance Brain Imaging—A Novel Unsupervised Machine Learning Approach

Meeting Abstracts

492-P: Utility of Measures of Nerve Fiber Function and Structure for the Diagnosis of Diabetic Peripheral Neuropathy

CAROLINA M. CASELLINI, HENRI PARSON, COURTNY CUSHMAN, AMBER M. INGRAM, JORDAN L. PETTAWAY, TANEISHA SEARS, ELIAS S. SIRAJ

Diabetes 2023;72(Supplement_1):492-P

https://doi.org/10.2337/db23-492-P

Published: 20 June 2023

View article titled, 492-P: Utility of Measures of Nerve Fiber Function and Structure for the Diagnosis of Diabetic Peripheral Neuropathy

Meeting Abstracts

491-P: Corneal Nerve Sensitivity—Early Detection of Diabetic Peripheral Neuropathy (DPN)

MARK A. YOREK, MARCELO CORREIA, RANDY KARDON, PIETER POOLMAN

Diabetes 2023;72(Supplement_1):491-P

https://doi.org/10.2337/db23-491-P

Published: 20 June 2023

View article titled, 491-P: Corneal Nerve Sensitivity—Early Detection of Diabetic Peripheral Neuropathy (DPN)

Meeting Abstracts

486-P: Reduced Serum Netrin-1 Levels Correlate with Corneal Nerve Fiber Loss in Diabetic Neuropathy

ASIF MONDAL, CHIRANJIT BOSE, SUBHASISH PRAMANIK, AYAN MUKHERJEE, BIDISHA MUKHERJEE, SATINATH MUKHOPADHYAY

Diabetes 2023;72(Supplement_1):486-P

https://doi.org/10.2337/db23-486-P

Published: 20 June 2023

View article titled, 486-P: Reduced Serum Netrin-1 Levels Correlate with Corneal Nerve Fiber Loss in Diabetic Neuropathy

Meeting Abstracts

485-P: Proteomic Analysis Reveals Different Therapeutic Mechanisms for Diabetic Neuropathy between DPP-4 Inhibitor and SGLT2 Inhibitor

YUKI TAKEUCHI, SHO OSONOI, TAKANORI SASAKI, HIROKI MIZUKAMI

Diabetes 2023;72(Supplement_1):485-P

https://doi.org/10.2337/db23-485-P

Published: 20 June 2023

View article titled, 485-P: Proteomic Analysis Reveals Different Therapeutic Mechanisms for Diabetic Neuropathy between DPP-4 Inhibitor and SGLT2 Inhibitor

Meeting Abstracts

103-OR: LX9211, an Orally-Administered, Non-opioid, AAK1 Inhibitor for Painful Diabetic Peripheral Neuropathy—Results from a Randomized, Double-Blind, Placebo-Controlled, Parallel-Group, Multicenter Study

RODICA BUSUI, ANAND PATEL, CHRISTINE N. SANG, CRAIG B. GRANOWITZ, PHILLIP L. BANKS, PHILLIP PIERCE, FRANKLIN W. SUN, SUMA GOPINATHAN

Diabetes 2023;72(Supplement_1):103-OR

https://doi.org/10.2337/db23-103-OR

Published: 20 June 2023

View article titled, 103-OR: LX9211, an Orally-Administered, Non-opioid, AAK1 Inhibitor for Painful Diabetic Peripheral Neuropathy—Results from a Randomized, Double-Blind, Placebo-Controlled, Parallel-Group, Multicenter Study

Meeting Abstracts

478-P: Brain Volume Changes after Long-Term Opioid Treatment in Painful Diabetic Peripheral Neuropathy

GORDON P. SLOAN, KEVIN TEH, PALLAI RAPPAI SHILLO, SOLOMON TESFAYE, DINESH SELVARAJAH, IAIN D. WILKINSON

Diabetes 2023;72(Supplement_1):478-P

https://doi.org/10.2337/db23-478-P

Published: 20 June 2023

View article titled, 478-P: Brain Volume Changes after Long-Term Opioid Treatment in Painful Diabetic Peripheral Neuropathy

Meeting Abstracts

477-P: Thalamic Mitochondrial and Neuronal Function Is Preserved in Painful Diabetic Peripheral Neuropathy—A Multimodal Magnetic Resonance Imaging Study

GORDON P. SLOAN, KEVIN TEH, DINESH SELVARAJAH, SOLOMON TESFAYE

Diabetes 2023;72(Supplement_1):477-P

https://doi.org/10.2337/db23-477-P

Published: 20 June 2023

View article titled, 477-P: Thalamic Mitochondrial and Neuronal Function Is Preserved in Painful Diabetic Peripheral Neuropathy—A Multimodal Magnetic Resonance Imaging Study

Meeting Abstracts

105-OR: Omega-3 Polyunsaturated Fatty Acids in the Treatment of Diabetic Peripheral Neuropathy—Is the Source Important?

MARK A. YOREK

Diabetes 2023;72(Supplement_1):105-OR

https://doi.org/10.2337/db23-105-OR

Published: 20 June 2023

View article titled, 105-OR: Omega-3 Polyunsaturated Fatty Acids in the Treatment of Diabetic Peripheral Neuropathy—Is the Source Important?

Meeting Abstracts

203-LB: Prevalence and Risk Factors of Diabetic Peripheral Neuropathy—A Population-Based Cross-Sectional Study in China

WEIMIN WANG, QIUHE JI, XINGWU RAN, CHENXI LI, YAOMING XUE, BO FENG, DALONG ZHU

Diabetes 2023;72(Supplement_1):203-LB

https://doi.org/10.2337/db23-203-LB

Published: 20 June 2023

View article titled, 203-LB: Prevalence and Risk Factors of Diabetic Peripheral Neuropathy—A Population-Based Cross-Sectional Study in China

Journal Articles

Higher Sensory Cortical Energy Metabolism in Painful Diabetic Neuropathy: Evidence From a Cerebral Magnetic Resonance Spectroscopy Study

Gordon Sloan, Adriana Anton, Sharon Caunt, Iain Wilkinson, Dinesh Selvarajah, Solomon Tesfaye

Diabetes 2023;72(7):1028–1034

https://doi.org/10.2337/db23-0051

Published: 14 April 2023

View article titled, Higher Sensory Cortical Energy Metabolism in Painful Diabetic Neuropathy: Evidence From a Cerebral Magnetic Resonance Spectroscopy Study

Journal Articles

Comparison of Novel Wide-Field In Vivo Corneal Confocal Microscopy With Skin Biopsy for Assessing Peripheral Neuropathy in Type 2 Diabetes

Reza A. Badian, Linnéa Ekman, Are Hugo Pripp, Tor Paaske Utheim, Elisabet Englund, Lars B. Dahlin, Olov Rolandsson, Neil Lagali

Diabetes 2023;72(7):908–917

https://doi.org/10.2337/db22-0863

Published: 14 April 2023

View article titled, Comparison of Novel Wide-Field In Vivo Corneal Confocal Microscopy With Skin Biopsy for Assessing Peripheral Neuropathy in Type 2 Diabetes

Journal Articles

In This Issue of Diabetes

Max Bingham, PhD

Diabetes 2023;72(2):157–158

https://doi.org/10.2337/db23-ti02

Published: 20 January 2023

View article titled, In This Issue of <em>Diabetes</em>

Journal Articles

Diametrical Effects of Glucose Levels on Microvascular Permeability of Peripheral Nerves in Patients With Type 2 Diabetes With and Without Diabetic Neuropathy

Christoph M. Mooshage, Lukas Schimpfle, Zoltan Kender, Julia Szendroedi, Sabine Heiland, Peter Nawroth, Martin Bendszus, Stefan Kopf, Felix T. Kurz, Johann M.E. Jende

Diabetes 2023;72(2):290–298

https://doi.org/10.2337/db22-0548

Published: 03 November 2022

View article titled, Diametrical Effects of Glucose Levels on Microvascular Permeability of Peripheral Nerves in Patients With Type 2 Diabetes With and Without Diabetic Neuropathy

Journal Articles

Diabetic Neuropathy in Hands: An Endemic Complication Waiting to Unfold?

Eva Sierra-Silvestre, Ricardo J. Andrade, Andrea C. Schroeter, Leanne Bisset, Michel W. Coppieters

Diabetes 2022;71(8):1785–1794

https://doi.org/10.2337/db21-1147

Published: 21 August 2022

View article titled, Diabetic Neuropathy in Hands: An Endemic Complication Waiting to Unfold?

Journal Articles

Issues and Events

Diabetes 2022;71(7):1597

https://doi.org/10.2337/db22-ie07

Published: 24 June 2022

View article titled, Issues and Events

NARROW

1809-PUB: Painful Diabetic Neuropathy—Patients Treated with High-Frequency (10 kHz) Spinal Cord Stimulation (SCS) Experience Significant Reductions in A1C and Weight

482-P: Behavioral Assessment of 10kHz Spinal Cord Stimulation–Mediated Pain Relief in a Rat Model of Painful Diabetic Neuropathy

481-P: 10kHz SCS Restores Mechanical and Thermal Neural Processing in a Rodent Model of Painful Diabetic Neuropathy

480-P: Synergistic Effects of Hyperglycemia and Dyslipidemia on Diabetic Neuropathy—High Glucose Aggravates Oxidized LDL-Induced Schwann Cell Death via Hyperactivation of TLR4

104-OR: Identifying Painful Diabetic Neuropathy Subtypes from Resting-State Functional Magnetic Resonance Brain Imaging—A Novel Unsupervised Machine Learning Approach

492-P: Utility of Measures of Nerve Fiber Function and Structure for the Diagnosis of Diabetic Peripheral Neuropathy

491-P: Corneal Nerve Sensitivity—Early Detection of Diabetic Peripheral Neuropathy (DPN)

486-P: Reduced Serum Netrin-1 Levels Correlate with Corneal Nerve Fiber Loss in Diabetic Neuropathy

485-P: Proteomic Analysis Reveals Different Therapeutic Mechanisms for Diabetic Neuropathy between DPP-4 Inhibitor and SGLT2 Inhibitor

103-OR: LX9211, an Orally-Administered, Non-opioid, AAK1 Inhibitor for Painful Diabetic Peripheral Neuropathy—Results from a Randomized, Double-Blind, Placebo-Controlled, Parallel-Group, Multicenter Study

478-P: Brain Volume Changes after Long-Term Opioid Treatment in Painful Diabetic Peripheral Neuropathy

477-P: Thalamic Mitochondrial and Neuronal Function Is Preserved in Painful Diabetic Peripheral Neuropathy—A Multimodal Magnetic Resonance Imaging Study

105-OR: Omega-3 Polyunsaturated Fatty Acids in the Treatment of Diabetic Peripheral Neuropathy—Is the Source Important?

203-LB: Prevalence and Risk Factors of Diabetic Peripheral Neuropathy—A Population-Based Cross-Sectional Study in China

Higher Sensory Cortical Energy Metabolism in Painful Diabetic Neuropathy: Evidence From a Cerebral Magnetic Resonance Spectroscopy Study

Comparison of Novel Wide-Field In Vivo Corneal Confocal Microscopy With Skin Biopsy for Assessing Peripheral Neuropathy in Type 2 Diabetes

In This Issue of Diabetes

Diametrical Effects of Glucose Levels on Microvascular Permeability of Peripheral Nerves in Patients With Type 2 Diabetes With and Without Diabetic Neuropathy

Diabetic Neuropathy in Hands: An Endemic Complication Waiting to Unfold?

Issues and Events

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