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Journal Articles

Development of Novel Tools for Dissection of Central Versus Peripheral Dopamine D2-Like Receptor Signaling in Dysglycemia

Alessandro Bonifazi, Michael Ellenberger, Zachary J. Farino, Despoina Aslanoglou, Rana Rais, Sandra Pereira, José O. Mantilla-Rivas, Comfort A. Boateng, Amy J. Eshleman, Aaron Janowsky, Margaret K. Hahn, Gary J. Schwartz, Barbara S. Slusher, Amy Hauck Newman, Zachary Freyberg
Journal: Diabetes
Diabetes 2024;73(9):1411–1425
https://doi.org/10.2337/db24-0175
Published: 13 June 2024
View article titled, Development of Novel Tools for Dissection of Central Versus Peripheral Dopamine D<sub>2</sub>-Like Receptor Signaling in Dysglycemia
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Journal Articles

Comment on Tabatabaei Dakhili et al. The Antipsychotic Dopamine 2 Receptor Antagonist Diphenylbutylpiperidines Improve Glycemia in Experimental Obesity by Inhibiting Succinyl-CoA:3-Ketoacid CoA Transferase. Diabetes 2023;72:126–134

Gavin P. Reynolds
Journal: Diabetes
Diabetes 2023;72(5):e5
https://doi.org/10.2337/db23-0088
Published: 20 April 2023
View article titled, Comment on Tabatabaei Dakhili et al. The Antipsychotic Dopamine 2 Receptor Antagonist Diphenylbutylpiperidines Improve Glycemia in Experimental Obesity by Inhibiting Succinyl-CoA:3-Ketoacid CoA Transferase. Diabetes 2023;72:126–134
Open the PDF for Comment on Tabatabaei Dakhili et al. The Antipsychotic Dopamine 2 Receptor Antagonist Diphenylbutylpiperidines Improve Glycemia in Experimental Obesity by Inhibiting Succinyl-CoA:3-Ketoacid CoA Transferase. Diabetes 2023;72:126–134 in another window
Journal Articles

Roles of Pancreatic Islet Catecholamine Neurotransmitters in Glycemic Control and in Antipsychotic Drug–Induced Dysglycemia

Zachary Freyberg, George K. Gittes
Journal: Diabetes
Diabetes 2023;72(1):3–15
https://doi.org/10.2337/db22-0522
Published: 14 December 2022
View article titled, Roles of Pancreatic Islet Catecholamine Neurotransmitters in Glycemic Control and in Antipsychotic Drug–Induced Dysglycemia
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Journal Articles

The Antipsychotic Dopamine 2 Receptor Antagonist Diphenylbutylpiperidines Improve Glycemia in Experimental Obesity by Inhibiting Succinyl-CoA:3-Ketoacid CoA Transferase

Seyed Amirhossein Tabatabaei Dakhili, Amanda A. Greenwell, Kunyan Yang, Rabih Abou Farraj, Christina T. Saed, Keshav Gopal, Jordan S.F. Chan, Jadin J. Chahade, Farah Eaton, Crystal Lee, Carlos A. Velázquez-Martínez, Peter A. Crawford, J.N. Mark Glover, Rami Al Batran, John R. Ussher
Journal: Diabetes
Diabetes 2023;72(1):126–134
https://doi.org/10.2337/db22-0221
Published: 18 October 2022
View article titled, The Antipsychotic Dopamine 2 Receptor Antagonist Diphenylbutylpiperidines Improve Glycemia in Experimental Obesity by Inhibiting Succinyl-CoA:3-Ketoacid CoA Transferase
Open the PDF for The Antipsychotic Dopamine 2 Receptor Antagonist Diphenylbutylpiperidines Improve Glycemia in Experimental Obesity by Inhibiting Succinyl-CoA:3-Ketoacid CoA Transferase in another window
Journal Articles

Sorting Out the Receptor Isoforms Underlying Dopamine Inhibition of Insulin Secretion

Melkam A. Kebede, David W. Piston
Journal: Diabetes
Diabetes 2022;71(9):1831–1833
https://doi.org/10.2337/dbi22-0018
Published: 11 August 2022
View article titled, Sorting Out the Receptor Isoforms Underlying Dopamine Inhibition of Insulin Secretion
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Journal Articles

Dopamine Negatively Regulates Insulin Secretion Through Activation of D1-D2 Receptor Heteromer

Fumiya Uefune, Toru Aonishi, Tetsuya Kitaguchi, Harumi Takahashi, Susumu Seino, Daisuke Sakano, Shoen Kume
Journal: Diabetes
Diabetes 2022;71(9):1946–1961
https://doi.org/10.2337/db21-0644
Published: 22 June 2022
View article titled, Dopamine Negatively Regulates Insulin Secretion Through Activation of D1-D2 Receptor Heteromer
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Meeting Abstracts

1299-P: Novel Tools to Dissect the Metabolic Roles of Central and Peripheral Dopamine D2-Like Receptors

ALESSANDRO BONIFAZI, MICHAEL P. ELLENBERGER, ZACHARY FARINO, RANA RAIS, JOSÉ MANTILLA-RIVAS, DESPOINA ASLANOGLOU, AARON JANOWSKY, BARBARA SLUSHER, GARY J. SCHWARTZ, AMY H. NEWMAN, ZACHARY FREYBERG
Journal: Diabetes
Diabetes 2022;71(Supplement_1):1299-P
https://doi.org/10.2337/db22-1299-P
Published: 01 June 2022
View article titled, 1299-P: Novel Tools to Dissect the Metabolic Roles of Central and Peripheral Dopamine D2-Like Receptors
Meeting Abstracts

1472-P: Dual Pancreatic Adrenergic and Dopaminergic Signaling as a Therapeutic Mechanism for Treatment of Dysglycemia by Bromocriptine

DESPOINA ASLANOGLOU, SUZANNE BERTERA, LAURA FRIGGERI, MARTA SANCHEZ SOTO, JEONGKYUNG LEE, XIANGNING XUE, RYAN LOGAN, ROB LANE, VIJAY YECHOOR, R BENJAMIN FREE, DAVID R. SIBLEY, RITA BOTTINO, ZACHARY FREYBERG
Journal: Diabetes
Diabetes 2022;71(Supplement_1):1472-P
https://doi.org/10.2337/db22-1472-P
Published: 01 June 2022
View article titled, 1472-P: Dual Pancreatic Adrenergic and Dopaminergic Signaling as a Therapeutic Mechanism for Treatment of Dysglycemia by Bromocriptine
Meeting Abstracts

171-OR: Dopaminergic Signaling in the Ventral Tegmental Area of the Brain Mediates the Impaired Sympathoadrenal Response to Hypoglycemia

RAHUL AGRAWAL, SUNNY SHARMA, SIMON FISHER
Journal: Diabetes
Diabetes 2021;70(Supplement_1):171-OR
https://doi.org/10.2337/db21-171-OR
Published: 01 June 2021
View article titled, 171-OR: Dopaminergic Signaling in the Ventral Tegmental Area of the Brain Mediates the Impaired Sympathoadrenal Response to Hypoglycemia
Journal Articles

VMAT2 Safeguards β-Cells Against Dopamine Cytotoxicity Under High-Fat Diet–Induced Stress

Daisuke Sakano, Fumiya Uefune, Hiraku Tokuma, Yuki Sonoda, Kumi Matsuura, Naoki Takeda, Naomi Nakagata, Kazuhiko Kume, Nobuaki Shiraki, Shoen Kume
Journal: Diabetes
Diabetes 2020;69(11):2377–2391
https://doi.org/10.2337/db20-0207
Published: 21 August 2020
View article titled, VMAT2 Safeguards β-Cells Against Dopamine Cytotoxicity Under High-Fat Diet–Induced Stress
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Journal Articles

Dopamine and Early Retinal Dysfunction in Diabetes: Insights From a Phase 1 Study

Thomas J. Wubben
Journal: Diabetes
Diabetes 2020;69(7):1339–1340
https://doi.org/10.2337/dbi20-0009
Published: 20 April 2020
View article titled, Dopamine and Early Retinal Dysfunction in Diabetes: Insights From a Phase 1 Study
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Meeting Abstracts

118-OR: Activation of Dopamine Signaling in the Brain Causes HAAF

ADRIANA VIEIRA DE ABREU, RAHUL AGRAWAL, ETHAN R. MEIER, OWEN CHAN, SIMON FISHER
Journal: Diabetes
Diabetes 2019;68(Supplement_1):118-OR
https://doi.org/10.2337/db19-118-OR
Published: 01 June 2019
View article titled, 118-OR: Activation of Dopamine Signaling in the Brain Causes HAAF
Meeting Abstracts

1798-P: Insulin Modulates Dopaminergic Tone in the Human Brain—A Combined PET/MRI Study

STEPHANIE KULLMANN, DOMINIK BLUM, BENJAMIN JAGHUTRIZ, BENJAMIN BENDER, HANS-ULRICH HAERING, CHRISTIAN LA FOUGÈRE, HUBERT PREISSL, ANDREAS FRITSCHE, MATTHIAS REIMOLD, MARTIN HENI
Journal: Diabetes
Diabetes 2019;68(Supplement_1):1798-P
https://doi.org/10.2337/db19-1798-P
Published: 01 June 2019
View article titled, 1798-P: Insulin Modulates Dopaminergic Tone in the Human Brain—A Combined PET/MRI Study
Meeting Abstracts

1811-P: Short Term Dopamine D1D2 Receptor Agonist Therapy Induces Long-Term Amelioration of Hyperglycemia in ob/ob Mice

SHUQIN LUO, MICHAEL EZROKHI, NICHOLAS COMINOS, BENJAMIN RAICHE, ANTHONY H. CINCOTTA
Journal: Diabetes
Diabetes 2019;68(Supplement_1):1811-P
https://doi.org/10.2337/db19-1811-P
Published: 01 June 2019
View article titled, 1811-P: Short Term Dopamine D1D2 Receptor Agonist Therapy Induces Long-Term Amelioration of Hyperglycemia in ob/ob Mice
Meeting Abstracts

1793-P: Dopamine D1 plus D2 Receptor Coactivation Ameliorates Metabolic Syndrome (MS) and Nonalcoholic Fatty Liver Disease (NAFLD) in Mice

MICHAEL EZROKHI, SHUQIN LUO, NICHOLAS COMINOS, BENJAMIN RAICHE, MELANIE GUSTAFSON, ANTHONY H. CINCOTTA
Journal: Diabetes
Diabetes 2019;68(Supplement_1):1793-P
https://doi.org/10.2337/db19-1793-P
Published: 01 June 2019
View article titled, 1793-P: Dopamine D1 plus D2 Receptor Coactivation Ameliorates Metabolic Syndrome (MS) and Nonalcoholic Fatty Liver Disease (NAFLD) in Mice
Meeting Abstracts

Silencing of Supramammillary Nucleus (SuMN) Dopaminergic Neuronal Activity Induces the Obese Glucose Intolerant State

YAHONG ZHANG, TSUNG-HUANG TSAI, MICHAEL EZROKHI, CARL STOELZEL, ANTHONY CINCOTTA
Journal: Diabetes
Diabetes 2018;67(Supplement_1):2036-P
https://doi.org/10.2337/db18-2036-P
Published: 01 July 2018
View article titled, Silencing of Supramammillary Nucleus (SuMN) Dopaminergic Neuronal Activity Induces the Obese Glucose Intolerant State
Journal Articles

Sweet Dopamine: Sucrose Preferences Relate Differentially to Striatal D2 Receptor Binding and Age in Obesity

Marta Y. Pepino, Sarah A. Eisenstein, Allison N. Bischoff, Samuel Klein, Stephen M. Moerlein, Joel S. Perlmutter, Kevin J. Black, Tamara Hershey
Journal: Diabetes
Diabetes 2016;65(9):2618–2623
https://doi.org/10.2337/db16-0407
Published: 15 June 2016
View article titled, Sweet Dopamine: Sucrose Preferences Relate Differentially to Striatal D<sub>2</sub> Receptor Binding and Age in Obesity
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Journal Articles

Intrarenal Dopamine Inhibits Progression of Diabetic Nephropathy

Ming-Zhi Zhang, Bing Yao, Shilin Yang, Haichun Yang, Suwan Wang, Xiaofeng Fan, Huiyong Yin, Agnes B. Fogo, Gilbert W. Moeckel, Raymond C. Harris
Journal: Diabetes
Diabetes 2012;61(10):2575–2584
https://doi.org/10.2337/db12-0046
Published: 13 September 2012
View article titled, Intrarenal Dopamine Inhibits Progression of Diabetic Nephropathy
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Journal Articles

Tempol Reduces Oxidative Stress, Improves Insulin Sensitivity, Decreases Renal Dopamine D1 Receptor Hyperphosphorylation, and Restores D1 Receptor–G-Protein Coupling and Function in Obese Zucker Rats

Anees Ahmad Banday, Aditi Marwaha, Lakshmi S. Tallam, Mustafa F. Lokhandwala
Journal: Diabetes
Diabetes 2005;54(7):2219–2226
https://doi.org/10.2337/diabetes.54.7.2219
Published: 01 July 2005
View article titled, Tempol Reduces Oxidative Stress, Improves Insulin Sensitivity, Decreases Renal Dopamine D1 Receptor Hyperphosphorylation, and Restores D1 Receptor–G-Protein Coupling and Function in Obese Zucker Rats
Open the PDF for Tempol Reduces Oxidative Stress, Improves Insulin Sensitivity, Decreases Renal Dopamine D1 Receptor Hyperphosphorylation, and Restores D1 Receptor–G-Protein Coupling and Function in Obese Zucker Rats in another window
Journal Articles

Involvement of Brain-Derived Neurotrophic Factor in Early Retinal Neuropathy of Streptozotocin-Induced Diabetes in Rats: Therapeutic Potential of Brain-Derived Neurotrophic Factor for Dopaminergic Amacrine Cells

Masaaki Seki, Takayuki Tanaka, Hiroyuki Nawa, Tomoaki Usui, Takeo Fukuchi, Kazuhito Ikeda, Haruki Abe, Nobuyuki Takei
Journal: Diabetes
Diabetes 2004;53(9):2412–2419
https://doi.org/10.2337/diabetes.53.9.2412
Published: 01 September 2004
View article titled, Involvement of Brain-Derived Neurotrophic Factor in Early Retinal Neuropathy of Streptozotocin-Induced Diabetes in Rats: <subtitle>Therapeutic Potential of Brain-Derived Neurotrophic Factor for Dopaminergic Amacrine Cells</subtitle>
Open the PDF for Involvement of Brain-Derived Neurotrophic Factor in Early Retinal Neuropathy of Streptozotocin-Induced Diabetes in Rats: <subtitle>Therapeutic Potential of Brain-Derived Neurotrophic Factor for Dopaminergic Amacrine Cells</subtitle> in another window