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Journal Articles

Restoration of Autophagic Flux Improves Endothelial Function in Diabetes Through Lowering Mitochondrial ROS-Mediated eNOS Monomerization

Lei Zhao, Cheng-Lin Zhang, Lei He, Qinghua Chen, Limei Liu, Lijing Kang, Jian Liu, Jiang-Yun Luo, Lingshan Gou, Dan Qu, Wencong Song, Chi Wai Lau, Ho Ko, Vincent C.T. Mok, Xiao Yu Tian, Li Wang, Yu Huang

Diabetes 2022;71(5):1099–1114

DOI: https://doi.org/10.2337/db21-0660

Published: 18 February 2022

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Journal Articles

CEPT1-Mediated Phospholipogenesis Regulates Endothelial Cell Function and Ischemia-Induced Angiogenesis Through PPARα

Mohamed A. Zayed, Xiaohua Jin, Chao Yang, Larisa Belaygorod, Connor Engel, Kshitij Desai, Nikolai Harroun, Omar Saffaf, Bruce W. Patterson, Fong-Fu Hsu, Clay F. Semenkovich

Diabetes 2021;70(2):549–561

DOI: https://doi.org/10.2337/db20-0635

Published: 19 December 2020

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Journal Articles

Endothelial Cells Derived From Patients With Diabetic Macular Edema Recapitulate Clinical Evaluations of Anti-VEGF Responsiveness Through the Neuronal Pentraxin 2 Pathway

Marta Vilà González, Magdalini Eleftheriadou, Sophia Kelaini, Hojjat Naderi-Meshkin, Shonagh Flanagan, Stephen Stewart, Gianni Virgili, David J. Grieve, Alan W. Stitt, Noemi Lois, Andriana Margariti

Diabetes 2020;69(10):2170–2185

DOI: https://doi.org/10.2337/db19-1068

Published: 13 August 2020

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Journal Articles

PI3Kδ as a Novel Therapeutic Target in Pathological Angiogenesis

Wenyi Wu, Guohong Zhou, Haote Han, Xionggao Huang, Heng Jiang, Shizuo Mukai, Andrius Kazlauskas, Jing Cui, Joanne Aiko Matsubara, Bart Vanhaesebroeck, Xiaobo Xia, Jiantao Wang, Hetian Lei

Diabetes 2020;69(4):736–748

DOI: https://doi.org/10.2337/db19-0713

Published: 08 January 2020

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Includes: Supplementary data

Journal Articles

Endothelial SHIP2 Suppresses Nox2 NADPH Oxidase–Dependent Vascular Oxidative Stress, Endothelial Dysfunction, and Systemic Insulin Resistance

Nicole T. Watt, Matthew C. Gage, Peysh A. Patel, Hema Viswambharan, Piruthivi Sukumar, Stacey Galloway, Nadira Y. Yuldasheva, Helen Imrie, Andrew M.N. Walker, Kathryn J. Griffin, Natalia Makava, Anna Skromna, Katherine Bridge, David J. Beech, Stéphane Schurmans, Stephen B. Wheatcroft, Mark T. Kearney, Richard M. Cubbon

Diabetes 2017;66(11):2808–2821

DOI: https://doi.org/10.2337/db17-0062

Published: 22 August 2017

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Includes: Supplementary data

Journal Articles

Identification of RUNX1 as a Mediator of Aberrant Retinal Angiogenesis

Jonathan D. Lam, Daniel J. Oh, Lindsay L. Wong, Dhanesh Amarnani, Cindy Park-Windhol, Angie V. Sanchez, Jonathan Cardona-Velez, Declan McGuone, Anat O. Stemmer-Rachamimov, Dean Eliott, Diane R. Bielenberg, Tave van Zyl, Lishuang Shen, Xiaowu Gai, Patricia A. D’Amore, Leo A. Kim, Joseph F. Arboleda-Velasquez

Diabetes 2017;66(7):1950–1956

DOI: https://doi.org/10.2337/db16-1035

Published: 11 April 2017

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Includes: Supplementary data

Journal Articles

Local Sphingosine Kinase 1 Activity Improves Islet Transplantation

Darling Rojas-Canales, Daniella Penko, Kay K. Myo Min, Kate A. Parham, Heshan Peiris, Rainer V. Haberberger, Stuart M. Pitson, Chris Drogemuller, Damien J. Keating, Shane T. Grey, Patrick T. Coates, Claudine S. Bonder, Claire F. Jessup

Diabetes 2017;66(5):1301–1311

DOI: https://doi.org/10.2337/db16-0837

Published: 07 February 2017

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Journal Articles

Overexpressing IRS1 in Endothelial Cells Enhances Angioblast Differentiation and Wound Healing in Diabetes and Insulin Resistance

Sayaka Katagiri, Kyoungmin Park, Yasutaka Maeda, Tata Nageswara Rao, Mogher Khamaisi, Qian Li, Hisashi Yokomizo, Akira Mima, Luca Lancerotto, Amy Wagers, Dennis P. Orgill, George L. King

Diabetes 2016;65(9):2760–2771

DOI: https://doi.org/10.2337/db15-1721

Published: 23 May 2016

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Includes: Supplementary data

Journal Articles

Methylglyoxal-Induced Endothelial Cell Loss and Inflammation Contribute to the Development of Diabetic Cardiomyopathy

Branka Vulesevic, Brian McNeill, Ferdinando Giacco, Kay Maeda, Nick J.R. Blackburn, Michael Brownlee, Ross W. Milne, Erik J. Suuronen

Diabetes 2016;65(6):1699–1713

DOI: https://doi.org/10.2337/db15-0568

Published: 08 March 2016

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Journal Articles

miR-200b Mediates Endothelial-to-Mesenchymal Transition in Diabetic Cardiomyopathy

Biao Feng, Yanan Cao, Shali Chen, Xuran Chu, Yanhui Chu, Subrata Chakrabarti

Diabetes 2016;65(3):768–779

DOI: https://doi.org/10.2337/db15-1033

Published: 30 December 2015

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Includes: Supplementary data

Journal Articles

Glucose-Dependent Insulinotropic Polypeptide Stimulates Osteopontin Expression in the Vasculature via Endothelin-1 and CREB

Diabetes 2016;65(1):239–254

DOI: https://doi.org/10.2337/db15-0122

Published: 22 September 2015

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Includes: Supplementary data

Journal Articles

Unacylated Ghrelin Induces Oxidative Stress Resistance in a Glucose Intolerance and Peripheral Artery Disease Mouse Model by Restoring Endothelial Cell miR-126 Expression

Gabriele Togliatto, Antonella Trombetta, Patrizia Dentelli, Sara Gallo, Arturo Rosso, Paolo Cotogni, Riccarda Granata, Rita Falcioni, Thomas Delale, Ezio Ghigo, Maria Felice Brizzi

Diabetes 2015;64(4):1370–1382

DOI: https://doi.org/10.2337/db14-0991

Published: 25 October 2014

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Includes: Supplementary data

Journal Articles

Sirtuin 6 Expression and Inflammatory Activity in Diabetic Atherosclerotic Plaques: Effects of Incretin Treatment

Maria Luisa Balestrieri, Maria Rosaria Rizzo, Michelangela Barbieri, Pasquale Paolisso, Nunzia D’Onofrio, Alfonso Giovane, Mario Siniscalchi, Fabio Minicucci, Celestino Sardu, Davide D’Andrea, Ciro Mauro, Franca Ferraraccio, Luigi Servillo, Fabio Chirico, Pasquale Caiazzo, Giuseppe Paolisso, Raffaele Marfella

Diabetes 2015;64(4):1395–1406

DOI: https://doi.org/10.2337/db14-1149

Published: 16 October 2014

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Includes: Supplementary data

Journal Articles

Placental Insufficiency Decreases Pancreatic Vascularity and Disrupts Hepatocyte Growth Factor Signaling in the Pancreatic Islet Endothelial Cell in Fetal Sheep

Paul J. Rozance, Miranda Anderson, Marina Martinez, Anna Fahy, Antoni R. Macko, Jenai Kailey, Gregory J. Seedorf, Steven H. Abman, William W. Hay, Jr., Sean W. Limesand

Diabetes 2015;64(2):555–564

DOI: https://doi.org/10.2337/db14-0462

Published: 22 September 2014

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Journal Articles

Endothelial Cells From Visceral Adipose Tissue Disrupt Adipocyte Functions in a Three-Dimensional Setting: Partial Rescue by Angiopoietin-1

Vanessa Pellegrinelli, Christine Rouault, Nicolas Veyrie, Karine Clément, Danièle Lacasa

Diabetes 2014;63(2):535–549

DOI: https://doi.org/10.2337/db13-0537

Published: 16 January 2014

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Includes: Supplementary data

Journal Articles

A Critical Role for Thioredoxin-Interacting Protein in Diabetes-Related Impairment of Angiogenesis

Diabetes 2014;63(2):675–687

DOI: https://doi.org/10.2337/db13-0417

Published: 16 January 2014

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Includes: Supplementary data

Journal Articles

The β-Cell/EC Axis: How Do Islet Cells Talk to Each Other?

Heshan Peiris, Claudine S. Bonder, P. Toby H. Coates, Damien J. Keating, Claire F. Jessup

Diabetes 2014;63(1):3–11

DOI: https://doi.org/10.2337/db13-0617

Published: 13 December 2013

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Journal Articles

VEGF Secreted by Hypoxic Müller Cells Induces MMP-2 Expression and Activity in Endothelial Cells to Promote Retinal Neovascularization in Proliferative Diabetic Retinopathy

Murilo Rodrigues, Xiaoban Xin, Kathleen Jee, Savalan Babapoor-Farrokhran, Fabiana Kashiwabuchi, Tao Ma, Imran Bhutto, Syed Junaid Hassan, Yassine Daoud, David Baranano, Sharon Solomon, Gerard Lutty, Gregg L. Semenza, Silvia Montaner, Akrit Sodhi

Diabetes 2013;62(11):3863–3873

DOI: https://doi.org/10.2337/db13-0014

Published: 18 October 2013

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Includes: Supplementary data

Journal Articles

Liver Sinusoidal Endothelial Cells Link Hyperinsulinemia to Hepatic Insulin Resistance

Kyoichiro Tsuchiya, Domenico Accili

Diabetes 2013;62(5):1478–1489

DOI: https://doi.org/10.2337/db12-1296

Published: 16 April 2013

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Includes: Supplementary data

Journal Articles

Increase of Palmitic Acid Concentration Impairs Endothelial Progenitor Cell and Bone Marrow–Derived Progenitor Cell Bioavailability: Role of the STAT5/PPARγ Transcriptional Complex

Antonella Trombetta, Gabriele Togliatto, Arturo Rosso, Patrizia Dentelli, Cristina Olgasi, Paolo Cotogni, Maria Felice Brizzi

Diabetes 2013;62(4):1245–1257

DOI: https://doi.org/10.2337/db12-0646

Published: 14 March 2013

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Includes: Supplementary data

NARROW

Restoration of Autophagic Flux Improves Endothelial Function in Diabetes Through Lowering Mitochondrial ROS-Mediated eNOS Monomerization

CEPT1-Mediated Phospholipogenesis Regulates Endothelial Cell Function and Ischemia-Induced Angiogenesis Through PPARα

Endothelial Cells Derived From Patients With Diabetic Macular Edema Recapitulate Clinical Evaluations of Anti-VEGF Responsiveness Through the Neuronal Pentraxin 2 Pathway

PI3Kδ as a Novel Therapeutic Target in Pathological Angiogenesis

Endothelial SHIP2 Suppresses Nox2 NADPH Oxidase–Dependent Vascular Oxidative Stress, Endothelial Dysfunction, and Systemic Insulin Resistance

Identification of RUNX1 as a Mediator of Aberrant Retinal Angiogenesis

Local Sphingosine Kinase 1 Activity Improves Islet Transplantation

Overexpressing IRS1 in Endothelial Cells Enhances Angioblast Differentiation and Wound Healing in Diabetes and Insulin Resistance

Methylglyoxal-Induced Endothelial Cell Loss and Inflammation Contribute to the Development of Diabetic Cardiomyopathy

miR-200b Mediates Endothelial-to-Mesenchymal Transition in Diabetic Cardiomyopathy

Glucose-Dependent Insulinotropic Polypeptide Stimulates Osteopontin Expression in the Vasculature via Endothelin-1 and CREB

Unacylated Ghrelin Induces Oxidative Stress Resistance in a Glucose Intolerance and Peripheral Artery Disease Mouse Model by Restoring Endothelial Cell miR-126 Expression

Sirtuin 6 Expression and Inflammatory Activity in Diabetic Atherosclerotic Plaques: Effects of Incretin Treatment

Placental Insufficiency Decreases Pancreatic Vascularity and Disrupts Hepatocyte Growth Factor Signaling in the Pancreatic Islet Endothelial Cell in Fetal Sheep

Endothelial Cells From Visceral Adipose Tissue Disrupt Adipocyte Functions in a Three-Dimensional Setting: Partial Rescue by Angiopoietin-1

A Critical Role for Thioredoxin-Interacting Protein in Diabetes-Related Impairment of Angiogenesis

The β-Cell/EC Axis: How Do Islet Cells Talk to Each Other?

VEGF Secreted by Hypoxic Müller Cells Induces MMP-2 Expression and Activity in Endothelial Cells to Promote Retinal Neovascularization in Proliferative Diabetic Retinopathy

Liver Sinusoidal Endothelial Cells Link Hyperinsulinemia to Hepatic Insulin Resistance

Increase of Palmitic Acid Concentration Impairs Endothelial Progenitor Cell and Bone Marrow–Derived Progenitor Cell Bioavailability: Role of the STAT5/PPARγ Transcriptional Complex

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