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Journal Articles

Association of serum very long-chain saturated fatty acids with changes in insulin sensitivity and beta-cell function: the PROspective Metabolism and Islet cell Evaluation (PROMISE) cohort

Kira Zhi Hua Lai, Zhila Semnani-Azad, Beatrice A Boucher, Ravi Retnakaran, Stewart B. Harris, Vasanti Malik, Richard P. Bazinet, Anthony J. Hanley

Diabetes db221050

https://doi.org/10.2337/db22-1050

Published: 16 August 2023

View article titled, Association of serum very long-chain saturated fatty acids with changes in insulin sensitivity and beta-cell function: the PROspective Metabolism and Islet cell Evaluation (PROMISE) cohort

Journal Articles

An integrated map of cell type-specific gene expression in pancreatic islets

Ruth M Elgamal, Parul Kudtarkar, Rebecca L Melton, Hannah M Mummey, Paola Benaglio, Mei-Lin Okino, Kyle J Gaulton

Diabetes db230130

https://doi.org/10.2337/db23-0130

Published: 15 August 2023

View article titled, An integrated map of cell type-specific gene expression in pancreatic islets

Journal Articles

An Enhancer Within Abcb11 Regulates G6pc2 in C57BL/6 Mouse Pancreatic Islets

Mark P. Keller, Emily M. Hawes, Kathryn L. Schueler, Donnie S. Stapleton, Kelly A. Mitok, Shane P. Simonett, James K. Oeser, Leesa L. Sampson, Alan D. Attie, Mark A. Magnuson, Richard M. O’Brien

Diabetes db230215

https://doi.org/10.2337/db23-0215

Published: 08 August 2023

View article titled, An Enhancer Within Abcb11 Regulates G6pc2 in C57BL/6 Mouse Pancreatic Islets

Journal Articles

Optimization of a Glucagon-Like Peptide 1 Receptor Antagonist Antibody for Treatment of Hyperinsulinism

Sean M. Peterson, Christine A. Juliana, Cameron F. Hu, Jinghua Chai, Carson Holliday, Kara Y. Chan, Ana G. Lujan Hernandez, Zoe Challocombe, Linya Wang, Zhen Han, Nikhil Haas, Ryan Stafford, Fumiko Axelrod, Tom Z. Yuan, Diva D. De León, Aaron K. Sato

Diabetes 2023;72(9):1320–1329

https://doi.org/10.2337/db22-1039

Published: 26 June 2023

View article titled, Optimization of a Glucagon-Like Peptide 1 Receptor Antagonist Antibody for Treatment of Hyperinsulinism

Meeting Abstracts

1808-PUB: Effective and Durable Stem-Cell-Enabled Therapy of Autoimmune T1DM in Rodents and Dogs Provides the Scientific Basis for the First-in-Human Trial Using I.P. Administered “Neo-Islets,” 3-D Organoids of Allogeneic Islet, and Mesenchymal Stromal Cells—The Omentum Becomes the New Endocrine Pancreas without the Need for Antirejection Drugs

ANNA GOOCH, CHRISTOF WESTENFELDER

Diabetes 2023;72(Supplement_1):1808-PUB

https://doi.org/10.2337/db23-1808-PUB

Published: 23 June 2023

View article titled, 1808-PUB: Effective and Durable Stem-Cell-Enabled Therapy of Autoimmune T1DM in Rodents and Dogs Provides the Scientific Basis for the First-in-Human Trial Using I.P. Administered “Neo-Islets,” 3-D Organoids of Allogeneic Islet, and Mesenchymal Stromal Cells—The Omentum Becomes the New Endocrine Pancreas without the Need for Antirejection Drugs

Meeting Abstracts

836-P: Glucose-Dependent Insulin Production and Insulin-Independence in Type 1 Diabetes from Stem Cell–Derived, Fully Differentiated Islet Cells—Updated Data from the VX-880 Clinical Trial

TREVOR W. REICHMAN, CAMILLO RICORDI, ALI NAJI, JAMES F. MARKMANN, BRUCE A. PERKINS, MARTIN WIJKSTROM, STEVEN PARASKEVAS, BOTE BRUINSMA, GAUTHAM MARIGOWDA, JUDY L. SHIH, CHENKUN WANG, DOUGLAS MELTON, FELICIA PAGLIUCA, BASTIANO SANNA, LESLIE S. KEAN, ANNE L. PETERS, PIOTR WITKOWSKI, MICHAEL R. RICKELS

Diabetes 2023;72(Supplement_1):836-P

https://doi.org/10.2337/db23-836-P

Published: 23 June 2023

View article titled, 836-P: Glucose-Dependent Insulin Production and Insulin-Independence in Type 1 Diabetes from Stem Cell–Derived, Fully Differentiated Islet Cells—Updated Data from the VX-880 Clinical Trial

Meeting Abstracts

1777-P: Three-Dimensional Imaging Reveals Pancreatic Islet Fast Calcium Wave Origin Formation

YI YU

Diabetes 2023;72(Supplement_1):1777-P

https://doi.org/10.2337/db23-1777-P

Published: 20 June 2023

View article titled, 1777-P: Three-Dimensional Imaging Reveals Pancreatic Islet Fast Calcium Wave Origin Formation

Meeting Abstracts

229-LB: Generation of Human CAR-Treg Cells for Inducing Immunological Tolerance against Diabetogenic T Cells in Human Pancreatic Islets

SHAHNAWAZ IMAM, SHAFIYA IMTIAZ RAFIQI, JUAN C. JAUME

Diabetes 2023;72(Supplement_1):229-LB

https://doi.org/10.2337/db23-229-LB

Published: 20 June 2023

View article titled, 229-LB: Generation of Human CAR-Treg Cells for Inducing Immunological Tolerance against Diabetogenic T Cells in Human Pancreatic Islets

Meeting Abstracts

199-OR: Optogenetic Control of Pancreatic Delta Cells Reveals Their Central Role in Hormone Release from Pancreatic Islets

HAIQIANG DOU, CAROLINE A. MIRANDA, JOHAN TOLÖ, QUAN ZHANG, PATRIK RORSMAN

Diabetes 2023;72(Supplement_1):199-OR

https://doi.org/10.2337/db23-199-OR

Published: 20 June 2023

View article titled, 199-OR: Optogenetic Control of Pancreatic Delta Cells Reveals Their Central Role in Hormone Release from Pancreatic Islets

Meeting Abstracts

1513-P: IAPP25 in Beta Cells and DNSP11 in Alpha Cells Inhibit IAPP37 Fibrillation

QING-RONG LIU, MIN ZHU, JOSEPHINE M. EGAN

Diabetes 2023;72(Supplement_1):1513-P

https://doi.org/10.2337/db23-1513-P

Published: 20 June 2023

View article titled, 1513-P: IAPP25 in Beta Cells and DNSP11 in Alpha Cells Inhibit IAPP37 Fibrillation

Meeting Abstracts

1757-P: δ-α Cell-to-Cell Interaction Modulates Pancreatic Islet Ca2+ Oscillation Modes

HUIXIA REN

Diabetes 2023;72(Supplement_1):1757-P

https://doi.org/10.2337/db23-1757-P

Published: 20 June 2023

View article titled, 1757-P: δ-α Cell-to-Cell Interaction Modulates Pancreatic Islet Ca2+ Oscillation Modes

Meeting Abstracts

1756-P: Extracellular Matrix Stiffness Mediates Insulin Secretion in Pancreatic Islets via Phosphofructokinase Activity

CHELSEA GARCIA, KEIFER HOLCOMB, NIKKI L. FARNSWORTH

Diabetes 2023;72(Supplement_1):1756-P

https://doi.org/10.2337/db23-1756-P

Published: 20 June 2023

View article titled, 1756-P: Extracellular Matrix Stiffness Mediates Insulin Secretion in Pancreatic Islets via Phosphofructokinase Activity

Meeting Abstracts

1746-P: The Role of Cell–Cell Junction Associated Mediator in Glucose-Stimulated Insulin Secretion of Pancreatic Islets

HAO WANG

Diabetes 2023;72(Supplement_1):1746-P

https://doi.org/10.2337/db23-1746-P

Published: 20 June 2023

View article titled, 1746-P: The Role of Cell–Cell Junction Associated Mediator in Glucose-Stimulated Insulin Secretion of Pancreatic Islets

Meeting Abstracts

135-OR: Mapping Cis-Regulatory Programs Affecting Diabetes Risk in Pancreatic Islet Cell Types Using Single-Cell Multimodal Profiling

HANNAH MUMMEY, WESTON ELISON, KATHA KORGAONKAR, YUN S. LEE, JACKLYN M. NEWSOME ASHMUS, PAOLA BENAGLIO, MICHAEL T. MILLER, JOCELYN E. MANNING FOX, ANNA L. GLOYN, PATRICK MACDONALD, SEBASTIAN PREISSL, KYLE J. GAULTON

Diabetes 2023;72(Supplement_1):135-OR

https://doi.org/10.2337/db23-135-OR

Published: 20 June 2023

View article titled, 135-OR: Mapping Cis-Regulatory Programs Affecting Diabetes Risk in Pancreatic Islet Cell Types Using Single-Cell Multimodal Profiling

Meeting Abstracts

1739-P: Ontogeny of Bihormonal Islet Cells within the Human Pancreas

JIWON HAHM, JUAN A. FERNANDEZ ANDRADE, EDITH ARANY, DAVID J. HILL

Diabetes 2023;72(Supplement_1):1739-P

https://doi.org/10.2337/db23-1739-P

Published: 20 June 2023

View article titled, 1739-P: Ontogeny of Bihormonal Islet Cells within the Human Pancreas

Meeting Abstracts

1738-P: Instrument-Free Single-Cell Resolution of Transcriptome in Mouse Pancreatic Islet Cells

DILYANA G. DIMITROVA, ALEXANDRINE LIBOZ, STANISLAV LIPIN, CARINE BEAUPERE, NATACHA ROBLOT, JUN KOMATSU, GHISLAINE GUILLEMAIN, BERTRAND BLONDEAU

Diabetes 2023;72(Supplement_1):1738-P

https://doi.org/10.2337/db23-1738-P

Published: 20 June 2023

View article titled, 1738-P: Instrument-Free Single-Cell Resolution of Transcriptome in Mouse Pancreatic Islet Cells

Meeting Abstracts

1735-P: The Dichotomic and Timely Regulation of SerpinB13 Plays a Role in Beta-Cell Neogenesis and Pancreatic Islet Expansion

YURY KRYVALAP, SHAWN Z. MENG, RIM HABTE, JAN CZYZYK

Diabetes 2023;72(Supplement_1):1735-P

https://doi.org/10.2337/db23-1735-P

Published: 20 June 2023

View article titled, 1735-P: The Dichotomic and Timely Regulation of SerpinB13 Plays a Role in Beta-Cell Neogenesis and Pancreatic Islet Expansion

Meeting Abstracts

1734-P: Polyhormonal Cells of the Pancreatic Islets in Congenital Hyperinsulinism

YULIYA KRIVOVA, ALEXANDRA E. PROSHCHINA, DILIARA GUBAEVA, MARIA MELIKYAN, DMITRY OTLYGA

Diabetes 2023;72(Supplement_1):1734-P

https://doi.org/10.2337/db23-1734-P

Published: 20 June 2023

View article titled, 1734-P: Polyhormonal Cells of the Pancreatic Islets in Congenital Hyperinsulinism

Journal Articles

In This Issue of Diabetes

Max Bingham, PhD

Diabetes 2023;72(7):823–824

https://doi.org/10.2337/db23-ti07

Published: 20 June 2023

View article titled, In This Issue of Diabetes

Meeting Abstracts

230-LB: A Composite Capsule Strategy Support Longevity of Microencapsulated Pancreatic ß Cells

TIAN QIN, ALEXANDRA M. SMINK, PAUL DE VOS

Diabetes 2023;72(Supplement_1):230-LB

https://doi.org/10.2337/db23-230-LB

Published: 20 June 2023

View article titled, 230-LB: A Composite Capsule Strategy Support Longevity of Microencapsulated Pancreatic ß Cells

NARROW

Association of serum very long-chain saturated fatty acids with changes in insulin sensitivity and beta-cell function: the PROspective Metabolism and Islet cell Evaluation (PROMISE) cohort

An integrated map of cell type-specific gene expression in pancreatic islets

An Enhancer Within Abcb11 Regulates G6pc2 in C57BL/6 Mouse Pancreatic Islets

Optimization of a Glucagon-Like Peptide 1 Receptor Antagonist Antibody for Treatment of Hyperinsulinism

836-P: Glucose-Dependent Insulin Production and Insulin-Independence in Type 1 Diabetes from Stem Cell–Derived, Fully Differentiated Islet Cells—Updated Data from the VX-880 Clinical Trial

1777-P: Three-Dimensional Imaging Reveals Pancreatic Islet Fast Calcium Wave Origin Formation

229-LB: Generation of Human CAR-Treg Cells for Inducing Immunological Tolerance against Diabetogenic T Cells in Human Pancreatic Islets

199-OR: Optogenetic Control of Pancreatic Delta Cells Reveals Their Central Role in Hormone Release from Pancreatic Islets

1513-P: IAPP25 in Beta Cells and DNSP11 in Alpha Cells Inhibit IAPP37 Fibrillation

1757-P: δ-α Cell-to-Cell Interaction Modulates Pancreatic Islet Ca2+ Oscillation Modes

1756-P: Extracellular Matrix Stiffness Mediates Insulin Secretion in Pancreatic Islets via Phosphofructokinase Activity

1746-P: The Role of Cell–Cell Junction Associated Mediator in Glucose-Stimulated Insulin Secretion of Pancreatic Islets

135-OR: Mapping Cis-Regulatory Programs Affecting Diabetes Risk in Pancreatic Islet Cell Types Using Single-Cell Multimodal Profiling

1739-P: Ontogeny of Bihormonal Islet Cells within the Human Pancreas

1738-P: Instrument-Free Single-Cell Resolution of Transcriptome in Mouse Pancreatic Islet Cells

1735-P: The Dichotomic and Timely Regulation of SerpinB13 Plays a Role in Beta-Cell Neogenesis and Pancreatic Islet Expansion

1734-P: Polyhormonal Cells of the Pancreatic Islets in Congenital Hyperinsulinism

In This Issue of Diabetes

230-LB: A Composite Capsule Strategy Support Longevity of Microencapsulated Pancreatic ß Cells

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