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Meeting Abstracts

833-P: Impact of Hypoglycemia on Insulin Titration and Fasting Plasma Glucose in Basal Insulin–Treated Type 2 Diabetes: A Subanalysis of the SoliMix Trial

FRANCESCO GIORGINO, JULIO ROSENSTOCK, ROBERT RITZEL, OGUZHAN DEYNELI, AGUSTINA ALVAREZ, ELISABETH SOUHAMI, LYDIE MELAS-MELT, RORY J. MCCRIMMON

Diabetes 2022;71(Supplement_1):833-P

DOI: https://doi.org/10.2337/db22-833-P

Published: 01 June 2022

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Meeting Abstracts

712-P: Suhoor Timing in T1DM Patients Fasting during Ramadan: A Randomized Crossover Trial

REEM ALAMOUDI, MISHARY A. ALASSIRI, ABDULRHMAN ALJAWHRJI, MAZIN M. ALMAGHRABI, DALIA S. BASULAYMAN, MAJED RAMADAN

Diabetes 2022;71(Supplement_1):712-P

DOI: https://doi.org/10.2337/db22-712-P

Published: 01 June 2022

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Meeting Abstracts

532-P: Voluntary Exercise during Food Restriction Promotes a Sustained Increase in Hepatic Oxidative Metabolism

STANISLAW DEJA, BLANKA KUCEJOVA, ADRIANNA MAURER, MONIKA N. MIZERSKA, XIAORONG FU, JOHN P. THYFAULT, SHAWN C. BURGESS

Diabetes 2022;71(Supplement_1):532-P

DOI: https://doi.org/10.2337/db22-532-P

Published: 01 June 2022

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Meeting Abstracts

389-P: A Six-Month Periodic Fasting Reduces Microalbuminuria and Improves Metabolic Control in Patients with Type 2 Diabetes and Diabetic Nephropathy: A Randomized Controlled Study

ALBA SULAJ, STEFAN KOPF, EKATERINA V. RAUCHHAUPT, ELISABETH KLIEMANK, MAIK BRUNE, ZOLTAN KENDER, HANNELORE BARTL, FABIOLA GARCIA-CORTIZO, KATARINA KLEPAC, ZHE HAN, VARUN KUMAR, VALTER LONGO, AURELIO TELEMAN, JUERGEN G. OKUN, JAKOB MORGENSTERN, THOMAS H. FLEMING, JULIA M. SZENDROEDI, STEPHAN HERZIG

Diabetes 2022;71(Supplement_1):389-P

DOI: https://doi.org/10.2337/db22-389-P

Published: 01 June 2022

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Meeting Abstracts

275-OR: Inhibition of Hepatic ACC Decreases Ketogenesis during Fasting due to Elevated Amino Acid Availability

STANISLAW DEJA, JUSTIN A. FLETCHER, BLANKA KUCEJOVA, MONIKA N. MIZERSKA, XIAORONG FU, CHAI-WAN KIM, JEFFREY BROWNING, JAMEY YOUNG, JAY D. HORTON, SHAWN C. BURGESS

Diabetes 2022;71(Supplement_1):275-OR

DOI: https://doi.org/10.2337/db22-275-OR

Published: 01 June 2022

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Meeting Abstracts

1131-P: Progression to Diabetes Despite a Baseline Fasting Plasma Glucose = 80mg/dL: A Population-Based Case-Control Study

SNEHA MOHAN, ADRIAN VELLA, AOIFE M. EGAN

Diabetes 2022;71(Supplement_1):1131-P

DOI: https://doi.org/10.2337/db22-1131-P

Published: 01 June 2022

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Meeting Abstracts

146-OR: Loss of Hydroxycarboxylic Acid Receptor 2 (HCA2) Affects Adipose Tissue Homeostasis in a Sex-Specific Manner during Prolonged Fasting

KAYLEEN J. MCCAFFERTY, EMILY BRINKER, EMILY GRAFF, TODD D. STEURY, MICHAEL W. GREENE, ROBERT L. JUDD

Diabetes 2022;71(Supplement_1):146-OR

DOI: https://doi.org/10.2337/db22-146-OR

Published: 01 June 2022

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Meeting Abstracts

1324-P: Short-Term Effects of Glycemia-Lowering Medications on ß-Cell Function in the GRADE Study

NEDA RASOULI, JEANINE ALBU, ROBERT M. COHEN, RALPH A. DEFRONZO, ELSA DIAZ, ALOKANANDA GHOSH, JOSE A. LUCHSINGER, JANET B. MCGILL, LAURE SAYYED KASSEM, WILLIAM SIVITZ, WILLIAM V. TAMBORLANE, KRISTINA UTZSCHNEIDER, NAJI YOUNES, STEVEN E. KAHN, GRADE RESEARCH GROUP

Diabetes 2022;71(Supplement_1):1324-P

DOI: https://doi.org/10.2337/db22-1324-P

Published: 01 June 2022

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Meeting Abstracts

12-OR: Preventing ß-Cell Death under Glucotoxic Conditions: The Role of ChREBPb

LIORA S. KATZ, GABRIEL BRILL, MARK A. HERMAN, ADOLFO GARCIA-OCANA, DONALD SCOTT

Diabetes 2022;71(Supplement_1):12-OR

DOI: https://doi.org/10.2337/db22-12-OR

Published: 01 June 2022

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Meeting Abstracts

225-LB: Impaired Microvascular Responses May Explain Health Disparities and Impaired Metabolic Flexibility in Hispanic Residents of the Rio Grande Valley

RYAN D. RUSSELL, YU LUN TAI, SMARAN MARUPUDI

Diabetes 2022;71(Supplement_1):225-LB

DOI: https://doi.org/10.2337/db22-225-LB

Published: 01 June 2022

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Meeting Abstracts

121-OR: Alternate-Day Fasting Combined with Endurance Exercise for the Treatment of Fatty Liver Disease

MARK EZPELETA, KELSEY GABEL, KRISTA VARADY, SHUHAO LIN, SOFIA CIENFUEGOS

Diabetes 2022;71(Supplement_1):121-OR

DOI: https://doi.org/10.2337/db22-121-OR

Published: 01 June 2022

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Meeting Abstracts

505-P: Fasting in Ramadan during the Peak of COVID-Pandemic: DAFNE Graduates Experience

MOHAMMAD IRSHAD, ABEER K. ELSAMAD, AMAL ABDULLAH, MAJDOLEEN AZIZIEH, JUMANA ALKANDARI, ANISHA VARGHESE, SAHAR MURAD, ETAB TAGHADOM, AMIRA MEGAHED, EBAA S. ALOZAIRI

Diabetes 2022;71(Supplement_1):505-P

DOI: https://doi.org/10.2337/db22-505-P

Published: 01 June 2022

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Meeting Abstracts

250-LB: Tead1—A Regulator of Adult ß-Cell Proliferation and Function

JEONGKYUNG LEE, RUYA LIU, FENG LI, VINNY NEGI, RAJAGANAPATHI JAGANNATHAN, MARK HUISING, KE MA, BEN SHIH, MOUSUMI MOULIK, VIJAY YECHOOR

Diabetes 2022;71(Supplement_1):250-LB

DOI: https://doi.org/10.2337/db22-250-LB

Published: 01 June 2022

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Meeting Abstracts

337-OR: Tirzepatide Improved Markers of Islet-Cell Function (Fasting Glucagon and HOMA2-B) and Insulin Sensitivity (Fasting Insulin and HOMA2-IR) Compared with Semaglutide in People with Type 2 Diabetes

KATELYN BROWN, LAURA FERNANDEZ LANDO, BRANDON BERGMAN, MELISSA K. THOMAS, BING LIU, CLARE LEE

Diabetes 2022;71(Supplement_1):337-OR

DOI: https://doi.org/10.2337/db22-337-OR

Published: 01 June 2022

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Meeting Abstracts

123-LB: Extended Fasting Reveals Effect of Canagliflozin to Mobilize Ketones in Canines

MARILYN ADER, RASHIN SEDIGHI, MORVARID KABIR, RICHARD N. BERGMAN

Diabetes 2022;71(Supplement_1):123-LB

DOI: https://doi.org/10.2337/db22-123-LB

Published: 01 June 2022

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Journal Articles

Fat Distribution Within the Pancreas According to Diabetes Status and Insulin Traits

Loren Skudder-Hill, Ivana R. Sequeira, Jaelim Cho, Juyeon Ko, Sally D. Poppitt, Maxim S. Petrov

Diabetes 2022;71(6):1182–1192

DOI: https://doi.org/10.2337/db21-0976

Published: 02 March 2022

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Journal Articles

Islet Autoimmunity Is Highly Prevalent and Associated With Diminished β-Cell Function in Patients With Type 2 Diabetes in the GRADE Study

Diabetes 2022;71(6):1261–1271

DOI: https://doi.org/10.2337/db21-0590

Published: 21 January 2022

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Journal Articles

Nutrient Sensor mTORC1 Regulates Insulin Secretion by Modulating β-Cell Autophagy

Tal Israeli, Yael Riahi, Perla Garzon, Ruy Andrade Louzada, Joao Pedro Werneck-de-Castro, Manuel Blandino-Rosano, Roni Yeroslaviz-Stolper, Liat Kadosh, Sharona Tornovsky-Babeay, Gilad Hacker, Nitzan Israeli, Orly Agmon, Boaz Tirosh, Erol Cerasi, Ernesto Bernal-Mizrachi, Gil Leibowitz

Diabetes 2022;71(3):453–469

DOI: https://doi.org/10.2337/db21-0281

Published: 03 December 2021

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Journal Articles

SGLT2 Inhibition Increases Fasting Glucagon but Does Not Restore the Counterregulatory Hormone Response to Hypoglycemia in Participants With Type 1 Diabetes

Schafer C. Boeder, Justin M. Gregory, Erin R. Giovannetti, Jeremy H. Pettus

Diabetes 2022;71(3):511–519

DOI: https://doi.org/10.2337/db21-0769

Published: 02 December 2021

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Journal Articles

Genetic Studies of Metabolomics Change After a Liquid Meal Illuminate Novel Pathways for Glucose and Lipid Metabolism

Ruifang Li-Gao, David A. Hughes, Jan B. van Klinken, Renée de Mutsert, Frits R. Rosendaal, Dennis O. Mook-Kanamori, Nicholas J. Timpson, Ko Willems van Dijk

Diabetes 2021;70(12):2932–2946

DOI: https://doi.org/10.2337/db21-0397

Published: 05 October 2021

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2 3 4 5

NARROW

833-P: Impact of Hypoglycemia on Insulin Titration and Fasting Plasma Glucose in Basal Insulin–Treated Type 2 Diabetes: A Subanalysis of the SoliMix Trial

712-P: Suhoor Timing in T1DM Patients Fasting during Ramadan: A Randomized Crossover Trial

532-P: Voluntary Exercise during Food Restriction Promotes a Sustained Increase in Hepatic Oxidative Metabolism

389-P: A Six-Month Periodic Fasting Reduces Microalbuminuria and Improves Metabolic Control in Patients with Type 2 Diabetes and Diabetic Nephropathy: A Randomized Controlled Study

275-OR: Inhibition of Hepatic ACC Decreases Ketogenesis during Fasting due to Elevated Amino Acid Availability

1131-P: Progression to Diabetes Despite a Baseline Fasting Plasma Glucose = 80mg/dL: A Population-Based Case-Control Study

146-OR: Loss of Hydroxycarboxylic Acid Receptor 2 (HCA2) Affects Adipose Tissue Homeostasis in a Sex-Specific Manner during Prolonged Fasting

1324-P: Short-Term Effects of Glycemia-Lowering Medications on ß-Cell Function in the GRADE Study

12-OR: Preventing ß-Cell Death under Glucotoxic Conditions: The Role of ChREBPb

225-LB: Impaired Microvascular Responses May Explain Health Disparities and Impaired Metabolic Flexibility in Hispanic Residents of the Rio Grande Valley

121-OR: Alternate-Day Fasting Combined with Endurance Exercise for the Treatment of Fatty Liver Disease

505-P: Fasting in Ramadan during the Peak of COVID-Pandemic: DAFNE Graduates Experience

250-LB: Tead1—A Regulator of Adult ß-Cell Proliferation and Function

337-OR: Tirzepatide Improved Markers of Islet-Cell Function (Fasting Glucagon and HOMA2-B) and Insulin Sensitivity (Fasting Insulin and HOMA2-IR) Compared with Semaglutide in People with Type 2 Diabetes

123-LB: Extended Fasting Reveals Effect of Canagliflozin to Mobilize Ketones in Canines

Fat Distribution Within the Pancreas According to Diabetes Status and Insulin Traits

Islet Autoimmunity Is Highly Prevalent and Associated With Diminished β-Cell Function in Patients With Type 2 Diabetes in the GRADE Study

Nutrient Sensor mTORC1 Regulates Insulin Secretion by Modulating β-Cell Autophagy

SGLT2 Inhibition Increases Fasting Glucagon but Does Not Restore the Counterregulatory Hormone Response to Hypoglycemia in Participants With Type 1 Diabetes

Genetic Studies of Metabolomics Change After a Liquid Meal Illuminate Novel Pathways for Glucose and Lipid Metabolism

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