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Meeting Abstracts

1607-P: FGF1 Induces Glucokinase Upregulation and Increased Lactate Export in Mouse Hepatocytes

MORVARID KABIR, MARILYN ADER, NAREG THOMAS, EKIHIRO SEKI, RICHARD N. BERGMAN

Diabetes 2023;72(Supplement_1):1607-P

https://doi.org/10.2337/db23-1607-P

Published: 20 June 2023

View article titled, 1607-P: FGF1 Induces Glucokinase Upregulation and Increased Lactate Export in Mouse Hepatocytes

Meeting Abstracts

1527-P: Anorexia Induced by the Central Action of Fibroblast Growth Factor 1 (FGF1) Is Dependent on Reduced GABA Receptor Activation

JARRAD M. SCARLETT, KIMBERLY M. ALONGE, BAO ANH N. PHAN, GREGORY J. MORTON, MICHAEL W. SCHWARTZ

Diabetes 2023;72(Supplement_1):1527-P

https://doi.org/10.2337/db23-1527-P

Published: 20 June 2023

View article titled, 1527-P: Anorexia Induced by the Central Action of Fibroblast Growth Factor 1 (FGF1) Is Dependent on Reduced GABA Receptor Activation

Meeting Abstracts

1529-P: Hypothalamic FGF1 Regulates Systemic Glucose and Energy Homeostasis

HY EMI SHIN, JAE MYOUNG SUH

Diabetes 2023;72(Supplement_1):1529-P

https://doi.org/10.2337/db23-1529-P

Published: 20 June 2023

View article titled, 1529-P: Hypothalamic FGF1 Regulates Systemic Glucose and Energy Homeostasis

Meeting Abstracts

1384-P: Serum Fibroblast Growth Factor 1 Levels and Its Association with ß-Cell Function and Insulin Sensitivity in Adults with Glucose Intolerance

JI YOON KIM, JIMI CHOI, SIN GON KIM, NAM HOON KIM

Diabetes 2022;71(Supplement_1):1384-P

https://doi.org/10.2337/db22-1384-P

Published: 01 June 2022

View article titled, 1384-P: Serum Fibroblast Growth Factor 1 Levels and Its Association with ß-Cell Function and Insulin Sensitivity in Adults with Glucose Intolerance

Journal Articles

Erratum. The Hypothalamic Arcuate Nucleus–Median Eminence Is a Target for Sustained Diabetes Remission Induced by Fibroblast Growth Factor 1. Diabetes 2019;68: 1054–1061

Jenny M. Brown, Jarrad M. Scarlett, Miles E. Matsen, Hong T. Nguyen, Anna Secher, Rasmus Jorgensen, Gregory J. Morton, Michael W. Schwartz

Diabetes 2021;70(3):817

https://doi.org/10.2337/db21-er03a

Published: 18 December 2020

View article titled, Erratum. The Hypothalamic Arcuate Nucleus–Median Eminence Is a Target for Sustained Diabetes Remission Induced by Fibroblast Growth Factor 1. Diabetes 2019;68: 1054–1061

Meeting Abstracts

1771-P: Hypothalamic Perineuronal Net Assembly Is Required for Sustained Diabetes Remission Induced by FGF1

KIMBERLY M. ALONGE, ZAMAN MIRZADEH, JARRAD SCARLETT, ARIC LOGSDON, JENNY M. BROWN, ELAINE CABRALES, CHRISTINA K. CHAN, KARL KAIYALA, MARIE A. BENTSEN, WILLIAM A. BANKS, MIKLOS GUTTMAN, THOMAS N. WIGHT, GREGORY J. MORTON, MICHAEL W. SCHWARTZ

Diabetes 2020;69(Supplement_1):1771-P

https://doi.org/10.2337/db20-1771-P

Published: 01 June 2020

View article titled, 1771-P: Hypothalamic Perineuronal Net Assembly Is Required for Sustained Diabetes Remission Induced by FGF1

Meeting Abstracts

1831-P: Activating AMPK Mediates FGF1 Protection from NAFLD in Diabetic Mice

QIAN LIN, GENXIANG CAI, ZHENGSHUAI LIU, JINGYA LI, JIA LI, KUPPER A. WINTERGERST, PAUL N. EPSTEIN, LU CAI, YU LI, YI TAN

Diabetes 2020;69(Supplement_1):1831-P

https://doi.org/10.2337/db20-1831-P

Published: 01 June 2020

View article titled, 1831-P: Activating AMPK Mediates FGF1 Protection from NAFLD in Diabetic Mice

Meeting Abstracts

214-OR: Role of Hypothalamic MAPK/ERK Signaling in Diabetes Remission Induced by the Central Action of Fibroblast Growth Factor 1 (FGF1)

JENNY M. BROWN, BAO ANH N. PHAN, HUZAIFA WASANWALA, MILES E. MATSEN, ANNA SECHER, GREGORY J. MORTON, MICHAEL W. SCHWARTZ, JARRAD SCARLETT

Diabetes 2020;69(Supplement_1):214-OR

https://doi.org/10.2337/db20-214-OR

Published: 01 June 2020

View article titled, 214-OR: Role of Hypothalamic MAPK/ERK Signaling in Diabetes Remission Induced by the Central Action of Fibroblast Growth Factor 1 (FGF1)

Meeting Abstracts

1800-P: Transcriptomic Evidence of a Role for Neuron-Glia Interactions in Diabetes Remission Induced by the Central Action of Fibroblast Growth Factor 1 (FGF-1)

MARIE A. BENTSEN, DYLAN RAUSCH, ZAMAN MIRZADEH, JARRAD SCARLETT, JENNY M. BROWN, KIMBERLY M. ALONGE, THOMAS H. MEEK, ANNA SECHER, RASMUS JORGENSEN, TUNE PERS, MICHAEL W. SCHWARTZ

Diabetes 2019;68(Supplement_1):1800-P

https://doi.org/10.2337/db19-1800-P

Published: 01 June 2019

View article titled, 1800-P: Transcriptomic Evidence of a Role for Neuron-Glia Interactions in Diabetes Remission Induced by the Central Action of Fibroblast Growth Factor 1 (FGF-1)

Journal Articles

Central and Peripheral Administration of Fibroblast Growth Factor 1 Improves Pancreatic Islet Insulin Secretion in Diabetic Mouse Models

Katherine G. Tennant, Sarah R. Lindsley, Melissa A. Kirigiti, Cadence True, Paul Kievit

Diabetes 2019;68(7):1462–1472

https://doi.org/10.2337/db18-1175

Published: 02 May 2019

View article titled, Central and Peripheral Administration of Fibroblast Growth Factor 1 Improves Pancreatic Islet Insulin Secretion in Diabetic Mouse Models

Includes: Supplementary data

Journal Articles

The Hypothalamic Arcuate Nucleus–Median Eminence Is a Target for Sustained Diabetes Remission Induced by Fibroblast Growth Factor 1

Jenny M. Brown, Jarrad M. Scarlett, Miles E. Matsen, Hong T. Nguyen, Anna Secher, Rasmus Jorgensen, Gregory J. Morton, Michael W. Schwartz

Diabetes 2019;68(5):1054–1061

https://doi.org/10.2337/db19-0025

Published: 22 February 2019

View article titled, The Hypothalamic Arcuate Nucleus–Median Eminence Is a Target for Sustained Diabetes Remission Induced by Fibroblast Growth Factor 1

Journal Articles

Targeting the Brain to Cure Type 2 Diabetes

Bernard Thorens

Diabetes 2019;68(3):476–478

https://doi.org/10.2337/dbi18-0051

Published: 13 February 2019

View article titled, Targeting the Brain to Cure Type 2 Diabetes

Journal Articles

Peripheral Mechanisms Mediating the Sustained Antidiabetic Action of FGF1 in the Brain

Jarrad M. Scarlett, Kenjiro Muta, Jenny M. Brown, Jennifer M. Rojas, Miles E. Matsen, Nikhil K. Acharya, Anna Secher, Camilla Ingvorsen, Rasmus Jorgensen, Thomas Høeg-Jensen, Darko Stefanovski, Richard N. Bergman, Francesca Piccinini, Karl J. Kaiyala, Masakazu Shiota, Gregory J. Morton, Michael W. Schwartz

Diabetes 2019;68(3):654–664

https://doi.org/10.2337/db18-0498

Published: 06 December 2018

View article titled, Peripheral Mechanisms Mediating the Sustained Antidiabetic Action of FGF1 in the Brain

Includes: Supplementary data

Meeting Abstracts

An Action in the Hypothalamic Arcuate Nucleus Is Sufficient to Explain the Sustained Remission of Diabetes Induced by Central Administration of Fibroblast Growth Factor-1 (FGF-1)

JENNY M. BROWN, JARRAD SCARLETT, MILES E. MATSEN, ANNA SECHER, RASMUS JORGENSEN, GREGORY J. MORTON, MICHAEL W. SCHWARTZ

Diabetes 2018;67(Supplement_1):372-OR

https://doi.org/10.2337/db18-372-OR

Published: 01 July 2018

View article titled, An Action in the Hypothalamic Arcuate Nucleus Is Sufficient to Explain the Sustained Remission of Diabetes Induced by Central Administration of Fibroblast Growth Factor-1 (FGF-1)

Meeting Abstracts

Sustained Diabetes Remission Induced by the Central Action of Fibroblast Growth Factor-1 (FGF-1) Requires Activation of Integrin Receptor aνß3

JARRAD SCARLETT, JENNY M. BROWN, BAO ANH N. PHAN, EDDIE L. KHAV, MILES E. MATSEN, NIKHIL K. ACHARYA, HONG T. NGUYEN, ANNA SECHER, RASMUS JORGENSEN, GREGORY J. MORTON, MICHAEL W. SCHWARTZ

Diabetes 2018;67(Supplement_1):373-OR

https://doi.org/10.2337/db18-373-OR

Published: 01 July 2018

View article titled, Sustained Diabetes Remission Induced by the Central Action of Fibroblast Growth Factor-1 (FGF-1) Requires Activation of Integrin Receptor aνß3

Meeting Abstracts

A Single-Cell Transcriptomics Roadmap to Investigate Diabetes Remission Induced by the Central Action of Fibroblast Growth Factor-1 (FGF-1)

MARIE A. BENTSEN, DYLAN RAUSCH, JARRAD SCARLETT, KIMBERLY M. ALONGE, PASCAL N. TIMSHEL, ZAMAN MIRZADEH, ANNA SECHER, RASMUS JORGENSEN, TUNE PERS, MICHAEL W. SCHWARTZ

Diabetes 2018;67(Supplement_1):375-OR

https://doi.org/10.2337/db18-375-OR

Published: 01 July 2018

View article titled, A Single-Cell Transcriptomics Roadmap to Investigate Diabetes Remission Induced by the Central Action of Fibroblast Growth Factor-1 (FGF-1)

Journal Articles

FGF1 Mediates Overnutrition-Induced Compensatory β-Cell Differentiation

Mingyu Li, Patrick Page-McCaw, Wenbiao Chen

Diabetes 2016;65(1):96–109

https://doi.org/10.2337/db15-0085

Published: 29 September 2015

View article titled, FGF1 Mediates Overnutrition-Induced Compensatory β-Cell Differentiation

Includes: Supplementary data

Journal Articles

Identification of BMP and Activin Membrane-Bound Inhibitor (BAMBI) as a Potent Negative Regulator of Adipogenesis and Modulator of Autocrine/Paracrine Adipogenic Factors

Xiao Luo, Louise J. Hutley, Julie A. Webster, Yu-Hee Kim, Dong-Fang Liu, Felicity S. Newell, Charlotte H. Widberg, Anthony Bachmann, Nigel Turner, Carsten Schmitz-Peiffer, Johannes B. Prins, Gong-She Yang, Jonathan P. Whitehead

Diabetes 2012;61(1):124–136

https://doi.org/10.2337/db11-0998

Published: 12 December 2011

View article titled, Identification of BMP and Activin Membrane-Bound Inhibitor (BAMBI) as a Potent Negative Regulator of Adipogenesis and Modulator of Autocrine/Paracrine Adipogenic Factors

Includes: Supplementary data

Journal Articles

Fibroblast Growth Factor 1: A Key Regulator of Human Adipogenesis

Louise Hutley, Wenda Shurety, Felicity Newell, Ross McGeary, Nicole Pelton, Jennifer Grant, Adrian Herington, Donald Cameron, Jon Whitehead, Johannes Prins

Diabetes 2004;53(12):3097–3106

https://doi.org/10.2337/diabetes.53.12.3097

Published: 01 December 2004

View article titled, Fibroblast Growth Factor 1: <subtitle>A Key Regulator of Human Adipogenesis</subtitle>

NARROW

1607-P: FGF1 Induces Glucokinase Upregulation and Increased Lactate Export in Mouse Hepatocytes

1527-P: Anorexia Induced by the Central Action of Fibroblast Growth Factor 1 (FGF1) Is Dependent on Reduced GABA Receptor Activation

1529-P: Hypothalamic FGF1 Regulates Systemic Glucose and Energy Homeostasis

1384-P: Serum Fibroblast Growth Factor 1 Levels and Its Association with ß-Cell Function and Insulin Sensitivity in Adults with Glucose Intolerance

Erratum. The Hypothalamic Arcuate Nucleus–Median Eminence Is a Target for Sustained Diabetes Remission Induced by Fibroblast Growth Factor 1. Diabetes 2019;68: 1054–1061

1771-P: Hypothalamic Perineuronal Net Assembly Is Required for Sustained Diabetes Remission Induced by FGF1

1831-P: Activating AMPK Mediates FGF1 Protection from NAFLD in Diabetic Mice

214-OR: Role of Hypothalamic MAPK/ERK Signaling in Diabetes Remission Induced by the Central Action of Fibroblast Growth Factor 1 (FGF1)

1800-P: Transcriptomic Evidence of a Role for Neuron-Glia Interactions in Diabetes Remission Induced by the Central Action of Fibroblast Growth Factor 1 (FGF-1)

Central and Peripheral Administration of Fibroblast Growth Factor 1 Improves Pancreatic Islet Insulin Secretion in Diabetic Mouse Models

The Hypothalamic Arcuate Nucleus–Median Eminence Is a Target for Sustained Diabetes Remission Induced by Fibroblast Growth Factor 1

Targeting the Brain to Cure Type 2 Diabetes

Peripheral Mechanisms Mediating the Sustained Antidiabetic Action of FGF1 in the Brain

An Action in the Hypothalamic Arcuate Nucleus Is Sufficient to Explain the Sustained Remission of Diabetes Induced by Central Administration of Fibroblast Growth Factor-1 (FGF-1)

Sustained Diabetes Remission Induced by the Central Action of Fibroblast Growth Factor-1 (FGF-1) Requires Activation of Integrin Receptor aνß3

A Single-Cell Transcriptomics Roadmap to Investigate Diabetes Remission Induced by the Central Action of Fibroblast Growth Factor-1 (FGF-1)

FGF1 Mediates Overnutrition-Induced Compensatory β-Cell Differentiation

Identification of BMP and Activin Membrane-Bound Inhibitor (BAMBI) as a Potent Negative Regulator of Adipogenesis and Modulator of Autocrine/Paracrine Adipogenic Factors

Fibroblast Growth Factor 1: A Key Regulator of Human Adipogenesis

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