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Journal Articles

Tracking Insulin- and Glucagon-Expressing Cells In Vitro and In Vivo Using a Double-Reporter Human Embryonic Stem Cell Line

Samantha Mar, Ekaterina Filatov, Shugo Sasaki, Majid Mojibian, Dahai Zhang, Angela Yang, Cuilan Nian, Francis C. Lynn
Journal: Diabetes
Diabetes 2025;74(2):188–198
https://doi.org/10.2337/db24-0756
Published: 19 November 2024
View articletitled, Tracking Insulin- and Glucagon-Expressing Cells In Vitro and In Vivo Using a Double-Reporter Human Embryonic Stem Cell Line
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Journal Articles

Establishment of Pancreatic β-Cell–Specific Gene Knockout System Based on CRISPR-Cas9 Technology With AAV8-Mediated gRNA Delivery

Kyosei Ueki, Yuya Nishida, Shuhei Aoyama, Hirotsugu Uzawa, Akiko Kanai, Minami Ito, Koki Ikeda, Hitoshi Iida, Takeshi Miyatsuka, Hirotaka Watada
Journal: Diabetes
Diabetes 2023;72(11):1609–1620
https://doi.org/10.2337/db23-0445
Published: 25 August 2023
View articletitled, Establishment of Pancreatic β-Cell–Specific Gene Knockout System Based on CRISPR-Cas9 Technology With AAV8-Mediated gRNA Delivery
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Meeting Abstracts

201-OR: Characterization of Type 1 Diabetes (T1D) Endotypes

AMINA BEDRAT, TARUN PANT, SHUANG JIA, MARK ROETHLE, NATHAN A. TRUCHAN, SUSANNE M. CABRERA, YI-GUANG CHEN, CHIEN-WEI LIN, MARTIN HESSNER
Journal: Diabetes
Diabetes 2023;72(Supplement_1):201-OR
https://doi.org/10.2337/db23-201-OR
Published: 20 June 2023
View articletitled, 201-OR: Characterization of Type 1 Diabetes (T1D) Endotypes
Journal Articles

Protective Renalase Deficiency in β-Cells Shapes Immune Metabolism and Function in Autoimmune Diabetes

Kevin Bode, Tara MacDonald, Taylor Stewart, Bryhan Mendez, Erica P. Cai, Noelle Morrow, Yu-Chi Lee, Peng Yi, Stephan Kissler
Journal: Diabetes
Diabetes 2023;72(8):1127–1143
https://doi.org/10.2337/db23-0030
Published: 22 May 2023
View articletitled, Protective Renalase Deficiency in β-Cells Shapes Immune Metabolism and Function in Autoimmune Diabetes
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Journal Articles

Mitochondrial Genome–Encoded Long Noncoding RNA and Mitochondrial Stability in Diabetic Retinopathy

Jay Kumar, Ghulam Mohammad, Kumari Alka, Renu A. Kowluru
Journal: Diabetes
Diabetes 2023;72(4):520–531
https://doi.org/10.2337/db22-0744
Published: 23 December 2022
View articletitled, Mitochondrial Genome–Encoded Long Noncoding RNA and Mitochondrial Stability in Diabetic Retinopathy
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Journal Articles

Single-Cell RNA Sequencing Reveals a Role for Reactive Oxygen Species and Peroxiredoxins in Fatty Acid–Induced Rat β-Cell Proliferation

Alexis Vivoli, Julien Ghislain, Ali Filali-Mouhim, Zuraya Elisa Angeles, Anne-Laure Castell, Robert Sladek, Vincent Poitout
Journal: Diabetes
Diabetes 2023;72(1):45–58
https://doi.org/10.2337/db22-0121
Published: 03 October 2022
View articletitled, Single-Cell RNA Sequencing Reveals a Role for Reactive Oxygen Species and Peroxiredoxins in Fatty Acid–Induced Rat β-Cell Proliferation
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Journal Articles

Critical Role for Macrophages in the Developmental Programming of Pancreatic β-Cell Area in Offspring of Hypertensive Pregnancies

Kate M. Root, Brian Akhaphong, Melissa A. Cedars, Alexa M. Molin, Margaretta E. Huchthausen, Connor F. Laule, Ronald R. Regal, Emilyn U. Alejandro, Jean F. Regal
Journal: Diabetes
Diabetes 2022;71(12):2597–2611
https://doi.org/10.2337/db22-0404
Published: 20 September 2022
View articletitled, Critical Role for Macrophages in the Developmental Programming of Pancreatic β-Cell Area in Offspring of Hypertensive Pregnancies
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Meeting Abstracts

1450-P: Identifying Hidden Sources of Tissue Plasticity in Pancreatic Islets with a Novel Multicolor Flow Cytometry Approach

YURY KRYVALAP, SHAWN Z. MENG, JAN CZYZYK
Journal: Diabetes
Diabetes 2022;71(Supplement_1):1450-P
https://doi.org/10.2337/db22-1450-P
Published: 01 June 2022
View articletitled, 1450-P: Identifying Hidden Sources of Tissue Plasticity in Pancreatic Islets with a Novel Multicolor Flow Cytometry Approach
Journal Articles

Cytotoxicity-Related Gene Expression and Chromatin Accessibility Define a Subset of CD4+ T Cells That Mark Progression to Type 1 Diabetes

Naiara G. Bediaga, Alexandra L. Garnham, Gaetano Naselli, Esther Bandala-Sanchez, Natalie L. Stone, Joanna Cobb, Jessica E. Harbison, John M. Wentworth, Annette-G. Ziegler, Jennifer J. Couper, Gordon K. Smyth, Leonard C. Harrison
Journal: Diabetes
Diabetes 2022;71(3):566–577
https://doi.org/10.2337/db21-0612
Published: 18 January 2022
View articletitled, Cytotoxicity-Related Gene Expression and Chromatin Accessibility Define a Subset of CD4+ T Cells That Mark Progression to Type 1 Diabetes
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Meeting Abstracts

1257-P: LncRNA Kcnq1ot1 Affects Islet ß-Cell Proliferation and Insulin Secretion

YALAN CHEN, YANLI LI, ZIYU LIU, WEN XU, BEISI LIN, YANNA SU, JINHUA YAN, WANGEN LI
Journal: Diabetes
Diabetes 2021;70(Supplement_1):1257-P
https://doi.org/10.2337/db21-1257-P
Published: 01 June 2021
View articletitled, 1257-P: LncRNA Kcnq1ot1 Affects Islet ß-Cell Proliferation and Insulin Secretion
Meeting Abstracts

229-LB: Quantification of GLP-1R Internalization and Recycling in Live ß Cells

SARAH M. GRAY, KYLE SLOOP, PETER RAVN, JONATHAN CAMPBELL, DAVID A. D’ALESSIO
Journal: Diabetes
Diabetes 2021;70(Supplement_1):229-LB
https://doi.org/10.2337/db21-229-LB
Published: 01 June 2021
View articletitled, 229-LB: Quantification of GLP-1R Internalization and Recycling in Live ß Cells
Journal Articles

Virgin β-Cells at the Neogenic Niche Proliferate Normally and Mature Slowly

Sharon Lee, Jing Zhang, Supraja Saravanakumar, Marcus F. Flisher, David R. Grimm, Talitha van der Meulen, Mark O. Huising
Journal: Diabetes
Diabetes 2021;70(5):1070–1083
https://doi.org/10.2337/db20-0679
Published: 09 February 2021
View articletitled, Virgin β-Cells at the Neogenic Niche Proliferate Normally and Mature Slowly
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Journal Articles

Multinucleated Giant Cells in Adipose Tissue Are Specialized in Adipocyte Degradation

Julia Braune, Andreas Lindhorst, Janine Fröba, Constance Hobusch, Peter Kovacs, Matthias Blüher, Jens Eilers, Ingo Bechmann, Martin Gericke
Journal: Diabetes
Diabetes 2021;70(2):538–548
https://doi.org/10.2337/db20-0293
Published: 06 November 2020
View articletitled, Multinucleated Giant Cells in Adipose Tissue Are Specialized in Adipocyte Degradation
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Journal Articles

Patrolling Monocytes Are Recruited and Activated by Diabetes to Protect Retinal Microvessels

Francesco Tecilazich, Toan A. Phan, Fabio Simeoni, Giulia Maria Scotti, Zeina Dagher, Mara Lorenzi
Journal: Diabetes
Diabetes 2020;69(12):2709–2719
https://doi.org/10.2337/db19-1043
Published: 09 September 2020
View articletitled, Patrolling Monocytes Are Recruited and Activated by Diabetes to Protect Retinal Microvessels
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Journal Articles

A Multifunctional Role of Leucine-Rich α-2-Glycoprotein 1 in Cutaneous Wound Healing Under Normal and Diabetic Conditions

Chenghao Liu, Melissa Hui Yen Teo, Sharon Li Ting Pek, Xiaoting Wu, Mei Ling Leong, Hui Min Tay, Han Wei Hou, Christiane Ruedl, Stephen E. Moss, John Greenwood, Subramaniam Tavintharan, Wanjin Hong, Xiaomeng Wang
Journal: Diabetes
Diabetes 2020;69(11):2467–2480
https://doi.org/10.2337/db20-0585
Published: 04 September 2020
View articletitled, A Multifunctional Role of Leucine-Rich α-2-Glycoprotein 1 in Cutaneous Wound Healing Under Normal and Diabetic Conditions
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Journal Articles

Localized Immunosuppression With Tannic Acid Encapsulation Delays Islet Allograft and Autoimmune-Mediated Rejection

Jessie M. Barra, Veronika Kozlovskaya, Eugenia Kharlampieva, Hubert M. Tse
Journal: Diabetes
Diabetes 2020;69(9):1948–1960
https://doi.org/10.2337/db20-0248
Published: 25 June 2020
View articletitled, Localized Immunosuppression With Tannic Acid Encapsulation Delays Islet Allograft and Autoimmune-Mediated Rejection
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Meeting Abstracts

1769-P: Microglial Activation and Inactivation via Designer Receptors Exclusively Activated by Designer Drugs (DREADDs) Alters Peripheral Glucose Homeostasis

KELLY M. NESS, JOHN DOUGLASS, MARTIN VALDEARCOS-CONTRERAS, SR., MAURICIO D. DORFMAN, ANZELA NIRAULA, SUNEIL K. KOLIWAD, JOSHUA THALER
Journal: Diabetes
Diabetes 2020;69(Supplement_1):1769-P
https://doi.org/10.2337/db20-1769-P
Published: 01 June 2020
View articletitled, 1769-P: Microglial Activation and Inactivation via Designer Receptors Exclusively Activated by Designer Drugs (DREADDs) Alters Peripheral Glucose Homeostasis
Meeting Abstracts

262-OR: The Transcription Factor Yin Yang 1 (YY1) Is Critical to Beta-Cell Maintenance and Glucose Homeostasis

FLAVIA LETÍCIA M. PEÇANHA, ERNESTO BERNAL-MIZRACHI
Journal: Diabetes
Diabetes 2020;69(Supplement_1):262-OR
https://doi.org/10.2337/db20-262-OR
Published: 01 June 2020
View articletitled, 262-OR: The Transcription Factor Yin Yang 1 (YY1) Is Critical to Beta-Cell Maintenance and Glucose Homeostasis
Meeting Abstracts

2098-P: Transcriptomic Changes Associated with Oleate-Induced ß-Cell Proliferation in Rat Islets

ALEXIS VIVOLI, ANNE-LAURE CASTELL, ALAIN PACIS, ROBERT M. SLADEK, JULIEN GHISLAIN, VINCENT POITOUT
Journal: Diabetes
Diabetes 2020;69(Supplement_1):2098-P
https://doi.org/10.2337/db20-2098-P
Published: 01 June 2020
View articletitled, 2098-P: Transcriptomic Changes Associated with Oleate-Induced ß-Cell Proliferation in Rat Islets
Meeting Abstracts

92-OR: Using Bispecific Monoclonal Antibody to Reprogram the Development of Type 1 Diabetes

JOSEPH RAY CEPEDA, NITIN SESHADRI SEKHAR, JUNYING HAN, NINGYAN ZHANG, MASSIMO PIETROPAOLO, LI ZHANG
Journal: Diabetes
Diabetes 2019;68(Supplement_1):92-OR
https://doi.org/10.2337/db19-92-OR
Published: 01 June 2019
View articletitled, 92-OR: Using Bispecific Monoclonal Antibody to Reprogram the Development of Type 1 Diabetes