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Journal Articles

Nicotinic Signaling Stimulates Glucagon Secretion in Mouse and Human Pancreatic α-Cells

Alexander Hamilton, Quan Zhang, Rui Gao, Thomas G. Hill, Albert Salehi, Jakob G. Knudsen, Matthew B. Draper, Paul R.V. Johnson, Patrik Rorsman, Andrei I. Tarasov
Journal: Diabetes
Diabetes 2024;74(1):53–64
https://doi.org/10.2337/db23-0809
Published: 30 October 2024
View article titled, Nicotinic Signaling Stimulates Glucagon Secretion in Mouse and Human Pancreatic α-Cells
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Journal Articles

Leucine Suppresses α-Cell cAMP and Glucagon Secretion via a Combination of Cell-Intrinsic and Islet Paracrine Signaling

Emily R. Knuth, Hannah R. Foster, Erli Jin, Maia H. Ekstrand, Jakob G. Knudsen, Matthew J. Merrins
Journal: Diabetes
Diabetes 2024;73(9):1426–1439
https://doi.org/10.2337/db23-1013
Published: 13 June 2024
View article titled, Leucine Suppresses α-Cell cAMP and Glucagon Secretion via a Combination of Cell-Intrinsic and Islet Paracrine Signaling
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Journal Articles

Paper of the Month 2023 Winners

Journal: Diabetes
Diabetes 2024;73(1):3–4
https://doi.org/10.2337/db24-en01
Published: 20 December 2023
View article titled, Paper of the Month 2023 Winners
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Journal Articles

Daniel Porte Jr., 13 August 1931–13 May 2023

Steven E. Kahn, Stephen C. Woods, Jeffrey B. Halter, Gerald J. Taborsky, Michael W. Schwartz
Journal: Diabetes
Diabetes 2024;73(1):5–10
https://doi.org/10.2337/db23-0787
Published: 20 December 2023
View article titled, Daniel Porte Jr., 13 August 1931–13 May 2023
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Journal Articles

In This Issue of Diabetes

Max Bingham, PhD
Journal: Diabetes
Diabetes 2023;72(10):1345–1346
https://doi.org/10.2337/db23-ti10
Published: 20 September 2023
View article titled, In This Issue of <em>Diabetes</em>
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Journal Articles

Glucose Controls Glucagon Secretion by Regulating Fatty Acid Oxidation in Pancreatic α-Cells

Sarah L. Armour, Alexander Frueh, Margarita V. Chibalina, Haiqiang Dou, Lidia Argemi-Muntadas, Alexander Hamilton, Georgios Katzilieris-Petras, Peter Carmeliet, Benjamin Davies, Thomas Moritz, Lena Eliasson, Patrik Rorsman, Jakob G. Knudsen
Journal: Diabetes
Diabetes 2023;72(10):1446–1459
https://doi.org/10.2337/db23-0056
Published: 26 July 2023
View article titled, Glucose Controls Glucagon Secretion by Regulating Fatty Acid Oxidation in Pancreatic α-Cells
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Meeting Abstracts

1742-P: Loss of MAFB Compromises a-Cell Identity and Glucagon Secretion in Adult Human Islets

KATIE C. COATE, XIN TONG, JIN-HUA LIU, REGINA JENKINS, RADHIKA ARAMANDLA, NANDITA DEY, SEUNG KIM, MARCELA BRISSOVA, ALVIN C. POWERS, ROLAND STEIN
Journal: Diabetes
Diabetes 2023;72(Supplement_1):1742-P
https://doi.org/10.2337/db23-1742-P
Published: 20 June 2023
View article titled, 1742-P: Loss of MAFB Compromises a-Cell Identity and Glucagon Secretion in Adult Human Islets
Meeting Abstracts

200-OR: Role of Insulin-Degrading Enzyme (IDE) in the Tubulin–Primary Cilium Axis to Regulate Glucagon Secretion

ELENA CASANUEVA-ALVAREZ, ALBA SANZ-GONZÁLEZ, BEATRIZ MERINO, GERMAN PERDOMO, IRENE COZAR-CASTELLANO
Journal: Diabetes
Diabetes 2023;72(Supplement_1):200-OR
https://doi.org/10.2337/db23-200-OR
Published: 20 June 2023
View article titled, 200-OR: Role of Insulin-Degrading Enzyme (IDE) in the Tubulin–Primary Cilium Axis to Regulate Glucagon Secretion
Meeting Abstracts

1224-P: Glucagon Secretion Increases with Age in People with Type 2 Diabetes

SHIZUKA KANEKO, KAZUYA MOTOHASHI, YOKO UEBA, SHINSUKE TOKUMOTO
Journal: Diabetes
Diabetes 2023;72(Supplement_1):1224-P
https://doi.org/10.2337/db23-1224-P
Published: 20 June 2023
View article titled, 1224-P: Glucagon Secretion Increases with Age in People with Type 2 Diabetes
Meeting Abstracts

1645-P: Diabetes-Associated Variation in TCF7L2 Is Associated with a Longitudinal Decline in Glucose Tolerance Accompanied by Impaired Suppression of Postprandial Glucagon Secretion

MAYA ZEINI, KALPANA MUTHUSAMY, AOIFE M. EGAN, MARCELLO C. LAURENTI, CLAUDIO COBELLI, CHIARA DALLA MAN, ADRIAN VELLA
Journal: Diabetes
Diabetes 2023;72(Supplement_1):1645-P
https://doi.org/10.2337/db23-1645-P
Published: 20 June 2023
View article titled, 1645-P: Diabetes-Associated Variation in TCF7L2 Is Associated with a Longitudinal Decline in Glucose Tolerance Accompanied by Impaired Suppression of Postprandial Glucagon Secretion
Meeting Abstracts

1657-P: Post–Mixed Meal Glucagon Secretion Is Not Influenced by Residual Beta-Cell Function in Type 1 Diabetes

GUY TAYLOR, KIERAN SMITH, AYAT BASHIR, TIMOTHY J. MCDONALD, EMMA J. STEVENSON, JAMES A. SHAW, DANIEL J. WEST
Journal: Diabetes
Diabetes 2023;72(Supplement_1):1657-P
https://doi.org/10.2337/db23-1657-P
Published: 20 June 2023
View article titled, 1657-P: Post–Mixed Meal Glucagon Secretion Is Not Influenced by Residual Beta-Cell Function in Type 1 Diabetes
Journal Articles

In This Issue of Diabetes

Max Bingham, PhD
Journal: Diabetes
Diabetes 2023;72(2):157–158
https://doi.org/10.2337/db23-ti02
Published: 20 January 2023
View article titled, In This Issue of <em>Diabetes</em>
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Journal Articles

GC-Globulin/Vitamin D–Binding Protein Is Required for Pancreatic α-Cell Adaptation to Metabolic Stress

Katrina Viloria, Daniela Nasteska, Julia Ast, Annie Hasib, Federica Cuozzo, Silke Heising, Linford J.B. Briant, Martin Hewison, David J. Hodson
Journal: Diabetes
Diabetes 2023;72(2):275–289
https://doi.org/10.2337/db22-0326
Published: 29 November 2022
View article titled, GC-Globulin/Vitamin D–Binding Protein Is Required for Pancreatic α-Cell Adaptation to Metabolic Stress
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Journal Articles

RhoA as a Signaling Hub Controlling Glucagon Secretion From Pancreatic α-Cells

Xue Wen Ng, Yong Hee Chung, Farzad Asadi, Chen Kong, Alessandro Ustione, David W. Piston
Journal: Diabetes
Diabetes 2022;71(11):2384–2394
https://doi.org/10.2337/db21-1010
Published: 29 July 2022
View article titled, RhoA as a Signaling Hub Controlling Glucagon Secretion From Pancreatic α-Cells
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Journal Articles

The Liver–α-Cell Axis in Health and in Disease

Michael M. Richter, Katrine D. Galsgaard, Emilie Elmelund, Filip K. Knop, Malte P. Suppli, Jens J. Holst, Marie Winther-Sørensen, Sasha A.S. Kjeldsen, Nicolai J. Wewer Albrechtsen
Journal: Diabetes
Diabetes 2022;71(9):1852–1861
https://doi.org/10.2337/dbi22-0004
Published: 03 June 2022
View article titled, The Liver–α-Cell Axis in Health and in Disease
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Meeting Abstracts

1377-P: Pramlintide Lowers Postprandial Glucagon Concentrations by Inhibiting Glucagon Secretion without Altering Clearance in Type 1 Diabetes: A [13C15N]-Glucagon Study

FNU RUCHI, DAVIDE ROMERES, MICHELE SCHIAVON, SANTOSH RENUSE, AKHILESH PANDEY, CHIARA DALLA MAN, CLAUDIO COBELLI, RITA BASU, ANANDA BASU
Journal: Diabetes
Diabetes 2022;71(Supplement_1):1377-P
https://doi.org/10.2337/db22-1377-P
Published: 01 June 2022
View article titled, 1377-P: Pramlintide Lowers Postprandial Glucagon Concentrations by Inhibiting Glucagon Secretion without Altering Clearance in Type 1 Diabetes: A [13C15N]-Glucagon Study
Meeting Abstracts

229-LB: G6PC2, a GWAS Locus for Fasting Glucose and HbA1c, Regulates Glucose-Suppression of Glucagon Secretion in a-Cells

VARUN BAHL, CATHERINE L. MAY, HUMAN PANCREAS ANALYSIS PROGRAM, KLAUS H. KAESTNER
Journal: Diabetes
Diabetes 2022;71(Supplement_1):229-LB
https://doi.org/10.2337/db22-229-LB
Published: 01 June 2022
View article titled, 229-LB: G6PC2, a GWAS Locus for Fasting Glucose and HbA1c, Regulates Glucose-Suppression of Glucagon Secretion in a-Cells
Meeting Abstracts

230-LB: Amino Acid–Induced Glucagon Secretion and Glucagon Enhancement of Amino Acid Catabolism Is Independent of Glucose

KATHARINA MARUSZCZAK, CHRISTINE RASMUSSEN, FREDERIK R. CEUTZ, ANNE ØRGAARD, EMILIE E. CHRISTENSEN, MICHAEL M. RICHTER, JENS J. HOLST, MARIE WINTHER-SOERENSEN, NICOLAI J. WEWER ALBRECHTSEN
Journal: Diabetes
Diabetes 2022;71(Supplement_1):230-LB
https://doi.org/10.2337/db22-230-LB
Published: 01 June 2022
View article titled, 230-LB: Amino Acid–Induced Glucagon Secretion and Glucagon Enhancement of Amino Acid Catabolism Is Independent of Glucose
Meeting Abstracts

150-OR: The Use of Luminescent Cell-Based Assays for Studying Insulin and Glucagon Secretion and Activity

KIM HAUPT, DONNA M. LEIPPE, JOLANTA VIDUGIRIENE
Journal: Diabetes
Diabetes 2022;71(Supplement_1):150-OR
https://doi.org/10.2337/db22-150-OR
Published: 01 June 2022
View article titled, 150-OR: The Use of Luminescent Cell-Based Assays for Studying Insulin and Glucagon Secretion and Activity
Meeting Abstracts

367-OR: Elucidating Mechanisms of α-Cell Dysfunction in T1D

YASMINYE D. PETTWAY, CHUNHUA DAI, TIFFANY M. RICHARDSON, JOHN T. WALKER, RADHIKA ARAMANDLA, GREG POFFENBERGER, AMBER BRADLEY, ALVIN C. POWERS, MARCELA BRISSOVA
Journal: Diabetes
Diabetes 2022;71(Supplement_1):367-OR
https://doi.org/10.2337/db22-367-OR
Published: 01 June 2022
View article titled, 367-OR: Elucidating Mechanisms of α-Cell Dysfunction in T1D