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Journal Articles

Next-Generation HLA Sequence Analysis Uncovers Seven HLA-DQ Amino Acid Residues and Six Motifs Resistant to Childhood Type 1 Diabetes

Lue Ping Zhao, George K. Papadopoulos, William W. Kwok, Antonis K. Moustakas, George P. Bondinas, Annelie Carlsson, Helena Elding Larsson, Johnny Ludvigsson, Claude Marcus, Ulf Samuelsson, Ruihan Wang, Chul-Woo Pyo, Wyatt C. Nelson, Daniel E. Geraghty, Åke Lernmark

Diabetes 2020;69(11):2523–2535

DOI: https://doi.org/10.2337/db20-0374

Published: 31 August 2020

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Meeting Abstracts

1617-P: Association of High-Affinity Autoantibodies with High-Risk HLA Haplotypes

TAYLOR M. TRIOLO, LAURA PYLE, LIPING YU, PETER GOTTLIEB, ANDREA STECK

Diabetes 2020;69(Supplement_1):1617-P

DOI: https://doi.org/10.2337/db20-1617-P

Published: 01 June 2020

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Journal Articles

Motifs of Three HLA-DQ Amino Acid Residues (α44, β57, β135) Capture Full Association With the Risk of Type 1 Diabetes in DQ2 and DQ8 Children

Lue Ping Zhao, George K. Papadopoulos, William W. Kwok, Antonis K. Moustakas, George P. Bondinas, Helena Elding Larsson, Johnny Ludvigsson, Claude Marcus, Ulf Samuelsson, Ruihan Wang, Chul-Woo Pyo, Wyatt C. Nelson, Daniel E. Geraghty, Åke Lernmark

Diabetes 2020;69(7):1573–1587

DOI: https://doi.org/10.2337/db20-0075

Published: 03 April 2020

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Meeting Abstracts

1702-P: Fine-Scale Haplotype Mapping of PPM1K Gene Reveals New Genetic Markers for the Study of Insulin Resistance at Clinical Scale

SARA HAYDAR, CORINNE LAUTIER, FLORIN GRIGORESCU

Diabetes 2019;68(Supplement_1):1702-P

DOI: https://doi.org/10.2337/db19-1702-P

Published: 01 June 2019

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Journal Articles

Genetic Variation Within the HLA-DRA1 Gene Modulates Susceptibility to Type 1 Diabetes in HLA-DR3 Homozygotes

Özkan Aydemir, Janelle A. Noble, Jeffrey A. Bailey, Åke Lernmark, Patrick Marsh, Agnes Andersson Svärd, Frank Bearoff, Elizabeth P. Blankenhorn, John P. Mordes, Better Diabetes Diagnosis (BDD) Study Group, Martina Persson, Helena Elding Larsson, Gun Forsander, Sten-Anders Ivarsson, Johnny Ludvigsson, Claude Marcus, Annelie Carlsson

Diabetes 2019;68(7):1523–1527

DOI: https://doi.org/10.2337/db18-1128

Published: 08 April 2019

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Includes: Supplementary data

Meeting Abstracts

Conserved Haplotype in SGLT1 and Risk for Dietary Hyperglycemia

SARA B. SEIDELMANN, ELENA FEOFANOVA, BING YU, NORA FRANCESCHINI, BRIAN CLAGGETT, MIKKO KUOKKANEN, TAPANI M. EBELING, SR., MARKUS PEROLA, VEIKKO SALOMAA, AMIL SHAH, JOSEF CORESH, ELIZABETH SELVIN, CALUM A. MACRAE, SUSAN CHENG, ERIC BOERWINKLE, SCOTT SOLOMON

Diabetes 2018;67(Supplement_1):214-LB

DOI: https://doi.org/10.2337/db18-214-LB

Published: 01 July 2018

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Journal Articles

HLA-DRB115:01-DQA101:02-DQB1*06:02 Haplotype Protects Autoantibody-Positive Relatives From Type 1 Diabetes Throughout the Stages of Disease Progression

Alberto Pugliese, David Boulware, Liping Yu, Sunanda Babu, Andrea K. Steck, Dorothy Becker, Henry Rodriguez, Linda DiMeglio, Carmella Evans-Molina, Leonard C. Harrison, Desmond Schatz, Jerry P. Palmer, Carla Greenbaum, George S. Eisenbarth, Jay M. Sosenko, the Type 1 Diabetes TrialNet Study Group

Diabetes 2016;65(4):1109–1119

DOI: https://doi.org/10.2337/db15-1105

Published: 28 January 2016

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Includes: Supplementary data

Journal Articles

Next-Generation Sequencing Reveals That HLA-DRB3, -DRB4, and -DRB5 May Be Associated With Islet Autoantibodies and Risk for Childhood Type 1 Diabetes

Lue Ping Zhao, Shehab Alshiekh, Michael Zhao, Annelie Carlsson, Helena Elding Larsson, Gun Forsander, Sten A. Ivarsson, Johnny Ludvigsson, Ingrid Kockum, Claude Marcus, Martina Persson, Ulf Samuelsson, Eva Örtqvist, Chul-Woo Pyo, Wyatt C. Nelson, Daniel E. Geraghty, Åke Lernmark, for the Better Diabetes Diagnosis (BDD) Study Group

Diabetes 2016;65(3):710–718

DOI: https://doi.org/10.2337/db15-1115

Published: 06 January 2016

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Journal Articles

Early Onset of Diabetes in the Proband Is the Major Determinant of Risk in HLA DR3-DQ2/DR4-DQ8 Siblings

Kathleen M. Gillespie, Rachel J. Aitken, Isabel Wilson, Alistair J.K. Williams, Polly J. Bingley

Diabetes 2014;63(3):1041–1047

DOI: https://doi.org/10.2337/db13-0994

Published: 13 February 2014

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Journal Articles

HLA Class II Genotyping of African American Type 1 Diabetic Patients Reveals Associations Unique to African Haplotypes

Janelle A. Noble, Jameel Johnson, Julie A. Lane, Ana M. Valdes

Diabetes 2013;62(9):3292–3299

DOI: https://doi.org/10.2337/db13-0094

Published: 15 August 2013

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Includes: Supplementary data

Journal Articles

Next Generation Sequencing Reveals the Association of DRB3*02:02 With Type 1 Diabetes

Henry A. Erlich, Ana Maria Valdes, Shana L. McDevitt, Birgitte B. Simen, Lisbeth A. Blake, Kim R. McGowan, John A. Todd, Stephen S. Rich, Janelle A. Noble, for the Type 1 Diabetes Genetics Consortium (T1DGC)

Diabetes 2013;62(7):2618–2622

DOI: https://doi.org/10.2337/db12-1387

Published: 14 June 2013

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Includes: Supplementary data

Journal Articles

Transferability and Fine Mapping of Type 2 Diabetes Loci in African Americans: The Candidate Gene Association Resource Plus Study

Diabetes 2013;62(3):965–976

DOI: https://doi.org/10.2337/db12-0266

Published: 14 February 2013

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Includes: Supplementary data

Journal Articles

The ATP-Sensitive K⁺ Channel ABCC8 S1369A Type 2 Diabetes Risk Variant Increases MgATPase Activity

Mohammad Fatehi, Mobeen Raja, Christian Carter, Daniel Soliman, Andrew Holt, Peter E. Light

Diabetes 2012;61(1):241–249

DOI: https://doi.org/10.2337/db11-0371

Published: 12 December 2011

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Journal Articles

Erratum

Diabetes 2011;60(12):3308–3310

DOI: https://doi.org/10.2337/db11-er12

Published: 13 November 2011

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Journal Articles

Associations Between Paternally Transmitted Fetal IGF2 Variants and Maternal Circulating Glucose Concentrations in Pregnancy

Clive J. Petry, Rachel V. Seear, Dianne L. Wingate, Lucy Manico, Carlo L. Acerini, Ken K. Ong, Ieuan A. Hughes, David B. Dunger

Diabetes 2011;60(11):3090–3096

DOI: https://doi.org/10.2337/db11-0689

Published: 17 October 2011

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Includes: Supplementary data

Journal Articles

Identification of Metabolic Modifiers That Underlie Phenotypic Variations in Energy-Balance Regulation

Chia Lin Chang, James J. Cai, Po Jen Cheng, Ho Yen Chueh, Sheau Yu Teddy Hsu

Diabetes 2011;60(3):726–734

DOI: https://doi.org/10.2337/db10-1331

Published: 21 February 2011

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Includes: Supplementary data

Journal Articles

Resequencing and Analysis of Variation in the TCF7L2 Gene in African Americans Suggests That SNP rs7903146 Is the Causal Diabetes Susceptibility Variant

Nicholette D. Palmer, Jessica M. Hester, S. Sandy An, Adebowale Adeyemo, Charles Rotimi, Carl D. Langefeld, Barry I. Freedman, Maggie C.Y. Ng, Donald W. Bowden

Diabetes 2011;60(2):662–668

DOI: https://doi.org/10.2337/db10-0134

Published: 21 January 2011

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Includes: Supplementary data

Journal Articles

HLA Class I and Genetic Susceptibility to Type 1 Diabetes: Results From the Type 1 Diabetes Genetics Consortium

Janelle A. Noble, Ana Maria Valdes, Michael D. Varney, Joyce A. Carlson, Priscilla Moonsamy, Anna Lisa Fear, Julie A. Lane, Eva Lavant, Rebecca Rappner, Anthony Louey, Patrick Concannon, Josyf C. Mychaleckyj, Henry A. Erlich, for the Type 1 Diabetes Genetics Consortium

Diabetes 2010;59(11):2972–2979

DOI: https://doi.org/10.2337/db10-0699

Published: 26 August 2010

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Includes: Supplementary data

Journal Articles

HLA DPA1, DPB1 Alleles and Haplotypes Contribute to the Risk Associated With Type 1 Diabetes: Analysis of the Type 1 Diabetes Genetics Consortium Families

Michael D. Varney, Ana Maria Valdes, Joyce A. Carlson, Janelle A. Noble, Brian D. Tait, Persia Bonella, Eva Lavant, Anna Lisa Fear, Anthony Louey, Priscilla Moonsamy, Josyf C. Mychaleckyj, Henry Erlich, for the Type 1 Diabetes Genetics Consortium

Diabetes 2010;59(8):2055–2062

DOI: https://doi.org/10.2337/db09-0680

Published: 27 April 2010

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Journal Articles

Elevated MBL Concentrations Are Not an Indication of Association Between the MBL2 Gene and Type 1 Diabetes or Diabetic Nephropathy

Mari A. Kaunisto, Lisa Sjölind, Riitta Sallinen, Kim Pettersson-Fernholm, Markku Saraheimo, Sara Fröjdö, Carol Forsblom, Johan Fagerudd, Troels K. Hansen, Allan Flyvbjerg, Maija Wessman, Per-Henrik Groop, for the FinnDiane Study Group

Diabetes 2009;58(7):1710–1714

DOI: https://doi.org/10.2337/db08-1495

Published: 14 April 2009

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Includes: Supplementary data

2 3 4 5

NARROW

Next-Generation HLA Sequence Analysis Uncovers Seven HLA-DQ Amino Acid Residues and Six Motifs Resistant to Childhood Type 1 Diabetes

1617-P: Association of High-Affinity Autoantibodies with High-Risk HLA Haplotypes

Motifs of Three HLA-DQ Amino Acid Residues (α44, β57, β135) Capture Full Association With the Risk of Type 1 Diabetes in DQ2 and DQ8 Children

1702-P: Fine-Scale Haplotype Mapping of PPM1K Gene Reveals New Genetic Markers for the Study of Insulin Resistance at Clinical Scale

Genetic Variation Within the HLA-DRA1 Gene Modulates Susceptibility to Type 1 Diabetes in HLA-DR3 Homozygotes

Conserved Haplotype in SGLT1 and Risk for Dietary Hyperglycemia

HLA-DRB115:01-DQA101:02-DQB1*06:02 Haplotype Protects Autoantibody-Positive Relatives From Type 1 Diabetes Throughout the Stages of Disease Progression

Next-Generation Sequencing Reveals That HLA-DRB3, -DRB4, and -DRB5 May Be Associated With Islet Autoantibodies and Risk for Childhood Type 1 Diabetes

Early Onset of Diabetes in the Proband Is the Major Determinant of Risk in HLA DR3-DQ2/DR4-DQ8 Siblings

HLA Class II Genotyping of African American Type 1 Diabetic Patients Reveals Associations Unique to African Haplotypes

Next Generation Sequencing Reveals the Association of DRB3*02:02 With Type 1 Diabetes

Transferability and Fine Mapping of Type 2 Diabetes Loci in African Americans: The Candidate Gene Association Resource Plus Study

The ATP-Sensitive K⁺ Channel ABCC8 S1369A Type 2 Diabetes Risk Variant Increases MgATPase Activity

Erratum

Associations Between Paternally Transmitted Fetal IGF2 Variants and Maternal Circulating Glucose Concentrations in Pregnancy

Identification of Metabolic Modifiers That Underlie Phenotypic Variations in Energy-Balance Regulation

Resequencing and Analysis of Variation in the TCF7L2 Gene in African Americans Suggests That SNP rs7903146 Is the Causal Diabetes Susceptibility Variant

HLA Class I and Genetic Susceptibility to Type 1 Diabetes: Results From the Type 1 Diabetes Genetics Consortium

HLA DPA1, DPB1 Alleles and Haplotypes Contribute to the Risk Associated With Type 1 Diabetes: Analysis of the Type 1 Diabetes Genetics Consortium Families

Elevated MBL Concentrations Are Not an Indication of Association Between the MBL2 Gene and Type 1 Diabetes or Diabetic Nephropathy

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