1-20 of 275
hepatocytes
Close
Save search
Follow your search
Access your saved searches in your account
Would you like to receive an alert when new items match your search?
Close Modal
Sort by
Journal Articles

Epoxygenase Cyp2c44 Regulates Hepatic Lipid Metabolism and Insulin Signaling by Controlling FATP2 Localization and Activation of the DAG/PKCδ Axis

Kakali Ghoshal, James M. Luther, Suman B. Pakala, Sergei Chetyrkin, John R. Falck, Roy Zent, David H. Wasserman, Ambra Pozzi
Journal: Diabetes
Diabetes 2024;73(8):1229–1243
https://doi.org/10.2337/db23-0493
Published: 14 May 2024
View article titled, Epoxygenase <em>Cyp2c44</em> Regulates Hepatic Lipid Metabolism and Insulin Signaling by Controlling FATP2 Localization and Activation of the DAG/PKCδ Axis
Open the PDF for Epoxygenase <em>Cyp2c44</em> Regulates Hepatic Lipid Metabolism and Insulin Signaling by Controlling FATP2 Localization and Activation of the DAG/PKCδ Axis in another window
Journal Articles

Inhibition of HSP20 Ameliorates Steatotic Liver Disease by Stimulating ERK2-Dependent Autophagy

Yanli Miao, Yi Zhong, Yutian Li, Haojie Qin, Ling Yang, Guojun Cao, Yong Tang, Ting Yu, Di Fan, Yang Lu, Jiangtong Peng, Kai Huang
Journal: Diabetes
Diabetes 2024;73(6):909–925
https://doi.org/10.2337/db23-0688
Published: 11 March 2024
View article titled, Inhibition of HSP20 Ameliorates Steatotic Liver Disease by Stimulating ERK2-Dependent Autophagy
Open the PDF for Inhibition of HSP20 Ameliorates Steatotic Liver Disease by Stimulating ERK2-Dependent Autophagy in another window
Journal Articles

Coagulation Factor VII Fine-tunes Hepatic Steatosis by Blocking AKT-CD36–Mediated Fatty Acid Uptake

Yao Zhang, Quanxin Jiang, Xingxing Liang, Qiqi Qian, Jie Xiong, Chuchu Liu, Junting Xu, Ning Wang, Ying Xu, Peihui Zhou, Sijia Lu, Qian Zhou, Yanmei Yuan, Xuemei Fan, Junli Liu, Suzhen Chen
Journal: Diabetes
Diabetes 2024;73(5):682–700
https://doi.org/10.2337/db23-0814
Published: 23 February 2024
View article titled, Coagulation Factor VII Fine-tunes Hepatic Steatosis by Blocking AKT-CD36–Mediated Fatty Acid Uptake
Open the PDF for Coagulation Factor VII Fine-tunes Hepatic Steatosis by Blocking AKT-CD36–Mediated Fatty Acid Uptake in another window
Journal Articles

Metformin Disrupts Signaling and Metabolism in Fetal Hepatocytes

Karli S. Swenson, Dong Wang, Amanda K. Jones, Michael J. Nash, Rebecca O’Rourke, Diana L. Takahashi, Paul Kievit, Jon D. Hennebold, Kjersti M. Aagaard, Jacob E. Friedman, Kenneth L. Jones, Paul J. Rozance, Laura D. Brown, Stephanie R. Wesolowski
Journal: Diabetes
Diabetes 2023;72(9):1214–1227
https://doi.org/10.2337/db23-0089
Published: 22 June 2023
View article titled, Metformin Disrupts Signaling and Metabolism in Fetal Hepatocytes
Open the PDF for Metformin Disrupts Signaling and Metabolism in Fetal Hepatocytes in another window
Journal Articles

Reciprocal Regulation of Hepatic TGF-β1 and Foxo1 Controls Gluconeogenesis and Energy Expenditure

Quan Pan, Weiqi Ai, Yunmei Chen, Da Mi Kim, Zheng Shen, Wanbao Yang, Wen Jiang, Yuxiang Sun, Stephen Safe, Shaodong Guo
Journal: Diabetes
Diabetes 2023;72(9):1193–1206
https://doi.org/10.2337/db23-0180
Published: 21 June 2023
View article titled, Reciprocal Regulation of Hepatic TGF-β1 and Foxo1 Controls Gluconeogenesis and Energy Expenditure
Open the PDF for Reciprocal Regulation of Hepatic TGF-β1 and Foxo1 Controls Gluconeogenesis and Energy Expenditure in another window
Meeting Abstracts

1596-P: Homozygous Mutations in MFN2 Aggravated Fat Deposition in Mouse Hepatocytes

YUE YU, YINGYING LUO, XIANGHAI ZHOU, LINONG JI
Journal: Diabetes
Diabetes 2023;72(Supplement_1):1596-P
https://doi.org/10.2337/db23-1596-P
Published: 20 June 2023
View article titled, 1596-P: Homozygous Mutations in MFN2 Aggravated Fat Deposition in Mouse Hepatocytes
Meeting Abstracts

1593-P: Insulin-Degrading Enzyme (IDE) Regulates Glucagon Signalling and Mitochondrial Respiration in Hepatocytes

CARLOS M. GONZÁLEZ-CASIMIRO, PATRICIA CÁMARA-TORRES, BEATRIZ MERINO, JAIME SANTO-DOMINGO, MIGUEL A. DE LA FUENTE, ANDRÉS ALONSO, IRENE COZAR-CASTELLANO, GERMAN PERDOMO
Journal: Diabetes
Diabetes 2023;72(Supplement_1):1593-P
https://doi.org/10.2337/db23-1593-P
Published: 20 June 2023
View article titled, 1593-P: Insulin-Degrading Enzyme (IDE) Regulates Glucagon Signalling and Mitochondrial Respiration in Hepatocytes
Meeting Abstracts

1588-P: Translatable Modeling of Glucagon Actions in Human iPSC-Derived Hepatocytes Uniquely Predicts Differential Clinical Responses to Glucagon Analog Agonist Molecules

WILLIAM ROELL, AJIT REGMI, CHARLES T. BENSON, TAMER COSKUN, JULIE S. MOYERS, JORGE ALSINA-FERNANDEZ, MELISSA K. THOMAS
Journal: Diabetes
Diabetes 2023;72(Supplement_1):1588-P
https://doi.org/10.2337/db23-1588-P
Published: 20 June 2023
View article titled, 1588-P: Translatable Modeling of Glucagon Actions in Human iPSC-Derived Hepatocytes Uniquely Predicts Differential Clinical Responses to Glucagon Analog Agonist Molecules
Meeting Abstracts

289-OR: Defining Pathway-Selective Insulin Resistance in Type 2 Diabetes Using iPS Cell-Derived Hepatocytes

ARIJEET GATTU, ANNA KROOK, JULEEN R. ZIERATH, MATTHIAS MANN, C. RONALD KAHN
Journal: Diabetes
Diabetes 2023;72(Supplement_1):289-OR
https://doi.org/10.2337/db23-289-OR
Published: 20 June 2023
View article titled, 289-OR: Defining Pathway-Selective Insulin Resistance in Type 2 Diabetes Using iPS Cell-Derived Hepatocytes
Meeting Abstracts

1607-P: FGF1 Induces Glucokinase Upregulation and Increased Lactate Export in Mouse Hepatocytes

MORVARID KABIR, MARILYN ADER, NAREG THOMAS, EKIHIRO SEKI, RICHARD N. BERGMAN
Journal: Diabetes
Diabetes 2023;72(Supplement_1):1607-P
https://doi.org/10.2337/db23-1607-P
Published: 20 June 2023
View article titled, 1607-P: FGF1 Induces Glucokinase Upregulation and Increased Lactate Export in Mouse Hepatocytes
Meeting Abstracts

1568-P: Identification of Stage-Specific Hepatocytes That Contribute to Nonalcoholic Steatohepatitis Progression

YANG XIAO, KUN ZHU, YIFAN LIU, MITCHELL A. LAZAR
Journal: Diabetes
Diabetes 2023;72(Supplement_1):1568-P
https://doi.org/10.2337/db23-1568-P
Published: 20 June 2023
View article titled, 1568-P: Identification of Stage-Specific Hepatocytes That Contribute to Nonalcoholic Steatohepatitis Progression
Meeting Abstracts

1519-P: Role of Cyr61 in Palmitic Acid-Induced Insulin Resistance and Inflammation in Hepatocyte

YUJUNG HEO, DAE JUNG KIM, HAE JIN KIM, NAMI LEE, KWANWOO LEE, SUNG E.Y. CHOI, YUP Y. KANG, SEUNG JIN HAN, JA YOUNG JEON
Journal: Diabetes
Diabetes 2023;72(Supplement_1):1519-P
https://doi.org/10.2337/db23-1519-P
Published: 20 June 2023
View article titled, 1519-P: Role of Cyr61 in Palmitic Acid-Induced Insulin Resistance and Inflammation in Hepatocyte
Meeting Abstracts

1575-P: Glycerol Metabolism and Gluconeogenesis in Mice Lacking the Mitochondrial Pyruvate Carrier in Hepatocytes

NICOLE YIEW, DANIEL FERGUSON, KEVIN CHO, STANISLAW DEJA, CHAOWAPONG JARASVARAPARN, XIAORONG FU, ANDREW J. LUTKEWITTE, SANDIP MUKHERJEE, JASON M. SINGER, GARY J. PATTI, SHAWN C. BURGESS, BRIAN N. FINCK
Journal: Diabetes
Diabetes 2023;72(Supplement_1):1575-P
https://doi.org/10.2337/db23-1575-P
Published: 20 June 2023
View article titled, 1575-P: Glycerol Metabolism and Gluconeogenesis in Mice Lacking the Mitochondrial Pyruvate Carrier in Hepatocytes
Meeting Abstracts

261-LB: Hepatocyte Gdf15 Protects against CCL4-Induced Liver Injury Independent of Changes in Feeding and Inflammation

JAKE KASTROLL, MICHAEL J. JURCZAK, FIONA BELLO, AMBER VANDEVENDER, IAN J. SIPULA, JONATHAN ALDER
Journal: Diabetes
Diabetes 2023;72(Supplement_1):261-LB
https://doi.org/10.2337/db23-261-LB
Published: 20 June 2023
View article titled, 261-LB: Hepatocyte Gdf15 Protects against CCL4-Induced Liver Injury Independent of Changes in Feeding and Inflammation
Meeting Abstracts

903-P: Correlation of Gene Expression and Cellular Pathways in Insulin-Expressing Mouse Liver Cells Transduced with an Integrating Adeno-associated Viral Vector (AAV)

SERGIO JOSHUA, NAJAH T. NASSIF, ANN M. SIMPSON
Journal: Diabetes
Diabetes 2023;72(Supplement_1):903-P
https://doi.org/10.2337/db23-903-P
Published: 20 June 2023
View article titled, 903-P: Correlation of Gene Expression and Cellular Pathways in Insulin-Expressing Mouse Liver Cells Transduced with an Integrating Adeno-associated Viral Vector (AAV)
Journal Articles

Liver-Secreted Hexosaminidase A Regulates Insulin-Like Growth Factor Signaling and Glucose Transport in Skeletal Muscle

Magdalene K. Montgomery, Jacqueline Bayliss, Shuai Nie, William de Nardo, Stacey N. Keenan, Marziyeh Anari, Amanuiel Z. Taddese, Nicholas A. Williamson, Geraldine J. Ooi, Wendy A. Brown, Paul R. Burton, Paul Gregorevic, Craig A. Goodman, Kevin I. Watt, Matthew J. Watt
Journal: Diabetes
Diabetes 2023;72(6):715–727
https://doi.org/10.2337/db22-0590
Published: 29 December 2022
View article titled, Liver-Secreted Hexosaminidase A Regulates Insulin-Like Growth Factor Signaling and Glucose Transport in Skeletal Muscle
Open the PDF for Liver-Secreted Hexosaminidase A Regulates Insulin-Like Growth Factor Signaling and Glucose Transport in Skeletal Muscle in another window
Journal Articles

High-Fat Diet–Induced DeSUMOylation of E4BP4 Promotes Lipid Droplet Biogenesis and Liver Steatosis in Mice

Sujuan Wang, Meichan Yang, Pei Li, Julian Sit, Audrey Wong, Kyle Rodrigues, Daniel Lank, Deqiang Zhang, Kezhong Zhang, Lei Yin, Xin Tong
Journal: Diabetes
Diabetes 2023;72(3):348–361
https://doi.org/10.2337/db22-0332
Published: 12 December 2022
View article titled, High-Fat Diet–Induced DeSUMOylation of E4BP4 Promotes Lipid Droplet Biogenesis and Liver Steatosis in Mice
Open the PDF for High-Fat Diet–Induced DeSUMOylation of E4BP4 Promotes Lipid Droplet Biogenesis and Liver Steatosis in Mice in another window
Journal Articles

Systemic LSD1 Inhibition Prevents Aberrant Remodeling of Metabolism in Obesity

Bastian Ramms, Dennis P. Pollow, Han Zhu, Chelsea Nora, Austin R. Harrington, Ibrahim Omar, Philip L.S.M. Gordts, Matthew Wortham, Maike Sander
Journal: Diabetes
Diabetes 2022;71(12):2513–2529
https://doi.org/10.2337/db21-1131
Published: 28 September 2022
View article titled, Systemic LSD1 Inhibition Prevents Aberrant Remodeling of Metabolism in Obesity
Open the PDF for Systemic LSD1 Inhibition Prevents Aberrant Remodeling of Metabolism in Obesity in another window
Journal Articles

Maternal Exercise and Paternal Exercise Induce Distinct Metabolite Signatures in Offspring Tissues

Diego Hernández-Saavedra, Christina Markunas, Hirokazu Takahashi, Lisa A. Baer, Johan E. Harris, Michael F. Hirshman, Olga Ilkayeva, Christopher B. Newgard, Kristin I. Stanford, Laurie J. Goodyear
Journal: Diabetes
Diabetes 2022;71(10):2094–2105
https://doi.org/10.2337/db22-0341
Published: 15 July 2022
View article titled, Maternal Exercise and Paternal Exercise Induce Distinct Metabolite Signatures in Offspring Tissues
Open the PDF for Maternal Exercise and Paternal Exercise Induce Distinct Metabolite Signatures in Offspring Tissues in another window
Journal Articles

Long Noncoding RNA lncRHPL Regulates Hepatic VLDL Secretion by Modulating hnRNPU/BMAL1/MTTP Axis

Xuan Shen, Yajun Zhang, Xuetao Ji, Bo Li, Yuzhu Wang, Yun Huang, Xu Zhang, Jingxian Yu, Ruihan Zou, Dongdong Qin, Hongwen Zhou, Qian Wang, John Zhong Li
Journal: Diabetes
Diabetes 2022;71(9):1915–1928
https://doi.org/10.2337/db21-1145
Published: 30 June 2022
View article titled, Long Noncoding RNA lncRHPL Regulates Hepatic VLDL Secretion by Modulating hnRNPU/BMAL1/MTTP Axis
Open the PDF for Long Noncoding RNA lncRHPL Regulates Hepatic VLDL Secretion by Modulating hnRNPU/BMAL1/MTTP Axis in another window