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Journal Articles

Metrnl Alleviates Lipid Accumulation by Modulating Mitochondrial Homeostasis in Diabetic Nephropathy

Yuxia Zhou, Lu Liu, Bangming Jin, Yixuan Wu, Lifen Xu, Xuebing Chang, Laying Hu, Guifang Wang, Yali Huang, Lingyu Song, Tian Zhang, Yuanyuan Wang, Ying Xiao, Fan Zhang, Mingjun Shi, Lingling Liu, Tuanlao Wang, Rui Yan, Bing Guo
Journal: Diabetes
Diabetes 2023;72(5):611–626
DOI: https://doi.org/10.2337/db22-0680
Published: 22 February 2023
View article titled, Metrnl Alleviates Lipid Accumulation by Modulating Mitochondrial Homeostasis in Diabetic Nephropathy
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Journal Articles

Plasma Proteomic Risk Markers of Incident Type 2 Diabetes Reflect Physiologically Distinct Components of Glucose-Insulin Homeostasis

Héléne T. Cronjé, Michael Y. Mi, Thomas R. Austin, Mary L. Biggs, David S. Siscovick, Rozenn N. Lemaitre, Bruce M. Psaty, Russell P. Tracy, Luc Djoussé, Jorge R. Kizer, Joachim H. Ix, Prashant Rao, Jeremy M. Robbins, Jacob L. Barber, Mark A. Sarzynski, Clary B. Clish, Claude Bouchard, Kenneth J. Mukamal, Robert E. Gerszten, Majken K. Jensen
Journal: Diabetes
Diabetes 2023;72(5):666–673
DOI: https://doi.org/10.2337/db22-0628
Published: 07 February 2023
View article titled, Plasma Proteomic Risk Markers of Incident Type 2 Diabetes Reflect Physiologically Distinct Components of Glucose-Insulin Homeostasis
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Journal Articles

Adipocyte Thyroid Hormone β Receptor–Mediated Hormone Action Fine-tunes Intracellular Glucose and Lipid Metabolism and Systemic Homeostasis

Yiruo Ma, Siyi Shen, Ying Yan, Shengjie Zhang, Shengnan Liu, Zhili Tang, Jing Yu, Mei Ma, Zhoumin Niu, Zhuoyang Li, Yuting Wu, Lin Zhao, Zhiqiang Lu, Chunchun Wei, Weiping J. Zhang, Ying Xue, Qiwei Zhai, Yu Li, Cheng Hu, Jingjing Jiang, Yuying Li, Hao Ying
Journal: Diabetes
Diabetes 2023;72(5):562–574
DOI: https://doi.org/10.2337/db22-0656
Published: 01 February 2023
View article titled, Adipocyte Thyroid Hormone β Receptor–Mediated Hormone Action Fine-tunes Intracellular Glucose and Lipid Metabolism and Systemic Homeostasis
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Journal Articles

NRF2 and Diabetes: The Good, the Bad, and the Complex

Matthew Dodson, Aryatara Shakya, Annadurai Anandhan, Jinjing Chen, Joe G.N. Garcia, Donna D. Zhang
Journal: Diabetes
Diabetes 2022;71(12):2463–2476
DOI: https://doi.org/10.2337/db22-0623
Published: 21 November 2022
View article titled, NRF2 and Diabetes: The Good, the Bad, and the Complex
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Journal Articles

FGF13-Sensitive Alteration of Parkin Safeguards Mitochondrial Homeostasis in Endothelium of Diabetic Nephropathy

Jia Sun, Xueqiang Guan, Chao Niu, Peng Chen, Yuankuan Li, Xuejiao Wang, Lan Luo, Mengxue Liu, Yanni Shou, Xiaozhong Huang, Yan Cai, Junjie Zhu, Junfu Fan, Xiaokun Li, Litai Jin, Weitao Cong
Journal: Diabetes
Diabetes 2023;72(1):97–111
DOI: https://doi.org/10.2337/db22-0231
Published: 18 October 2022
View article titled, FGF13-Sensitive Alteration of Parkin Safeguards Mitochondrial Homeostasis in Endothelium of Diabetic Nephropathy
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Journal Articles

In This Issue of Diabetes

Max Bingham, PhD
Journal: Diabetes
Diabetes 2022;71(11):2235–2236
DOI: https://doi.org/10.2337/db22-ti11
Published: 13 October 2022
View article titled, In This Issue of Diabetes
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Journal Articles

Butyrate-Producing Bacteria and Insulin Homeostasis: The Microbiome and Insulin Longitudinal Evaluation Study (MILES)

Jinrui Cui, Gautam Ramesh, Martin Wu, Elizabeth T. Jensen, Osa Crago, Alain G. Bertoni, Chunxu Gao, Kristi L. Hoffman, Patricia A. Sheridan, Kari E. Wong, Alexis C. Wood, Yii-Der I. Chen, Jerome I. Rotter, Joseph F. Petrosino, Stephen S. Rich, Mark O. Goodarzi
Journal: Diabetes
Diabetes 2022;71(11):2438–2446
DOI: https://doi.org/10.2337/db22-0168
Published: 12 August 2022
View article titled, Butyrate-Producing Bacteria and Insulin Homeostasis: The Microbiome and Insulin Longitudinal Evaluation Study (MILES)
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Meeting Abstracts

1316-P: Brainstem Neurons Regulating Energy Homeostasis

ALEXANDER R. NECTOW
Journal: Diabetes
Diabetes 2022;71(Supplement_1):1316-P
DOI: https://doi.org/10.2337/db22-1316-P
Published: 01 June 2022
View article titled, 1316-P: Brainstem Neurons Regulating Energy Homeostasis
Meeting Abstracts

313-OR: A Cytoskeleton-Based Mechanism Regulates Lipid Metabolism and Energy Homeostasis in Brown Adipose Tissue

ASHLEY AGUILLARD, JUNE ARRICASTRES, JOYCE TZENG, DAMARIS LORENZO
Journal: Diabetes
Diabetes 2022;71(Supplement_1):313-OR
DOI: https://doi.org/10.2337/db22-313-OR
Published: 01 June 2022
View article titled, 313-OR: A Cytoskeleton-Based Mechanism Regulates Lipid Metabolism and Energy Homeostasis in Brown Adipose Tissue
Meeting Abstracts

146-OR: Loss of Hydroxycarboxylic Acid Receptor 2 (HCA2) Affects Adipose Tissue Homeostasis in a Sex-Specific Manner during Prolonged Fasting

KAYLEEN J. MCCAFFERTY, EMILY BRINKER, EMILY GRAFF, TODD D. STEURY, MICHAEL W. GREENE, ROBERT L. JUDD
Journal: Diabetes
Diabetes 2022;71(Supplement_1):146-OR
DOI: https://doi.org/10.2337/db22-146-OR
Published: 01 June 2022
View article titled, 146-OR: Loss of Hydroxycarboxylic Acid Receptor 2 (HCA2) Affects Adipose Tissue Homeostasis in a Sex-Specific Manner during Prolonged Fasting
Meeting Abstracts

1367-P: A Submembrane Cytoskeleton-Dependent Mechanism Modulates Mitochondrial Homeostasis and Skeletal Muscle Bioenergetics

KAYLEIGH VOOS, JOYCE TZENG, HA EUN CHOI, TREVOR PHARR, DAMARIS LORENZO
Journal: Diabetes
Diabetes 2022;71(Supplement_1):1367-P
DOI: https://doi.org/10.2337/db22-1367-P
Published: 01 June 2022
View article titled, 1367-P: A Submembrane Cytoskeleton-Dependent Mechanism Modulates Mitochondrial Homeostasis and Skeletal Muscle Bioenergetics
Journal Articles

Endogenous Lipid-GPR120 Signaling Modulates Pancreatic Islet Homeostasis to Different Extents

Ya-Qin Du, Xue-Ying Sha, Jie Cheng, Jin Wang, Jing-Yu Lin, Wen-Tao An, Wei Pan, Li-Jun Zhang, Xiao-Na Tao, Yun-Fei Xu, Ying-Li Jia, Zhao Yang, Peng Xiao, Ming Liu, Jin-Peng Sun, Xiao Yu
Journal: Diabetes
Diabetes 2022;71(7):1454–1471
DOI: https://doi.org/10.2337/db21-0794
Published: 26 April 2022
View article titled, Endogenous Lipid-GPR120 Signaling Modulates Pancreatic Islet Homeostasis to Different Extents
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Journal Articles

Imeglimin Ameliorates β-Cell Apoptosis by Modulating the Endoplasmic Reticulum Homeostasis Pathway

Jinghe Li, Ryota Inoue, Yu Togashi, Tomoko Okuyama, Aoi Satoh, Mayu Kyohara, Kuniyuki Nishiyama, Takahiro Tsuno, Daisuke Miyashita, Tatsuya Kin, A.M. James Shapiro, Resilind Su Ern Chew, Adrian Kee Keong Teo, Seiichi Oyadomari, Yasuo Terauchi, Jun Shirakawa
Journal: Diabetes
Diabetes 2022;71(3):424–439
DOI: https://doi.org/10.2337/db21-0123
Published: 29 September 2021
View article titled, Imeglimin Ameliorates β-Cell Apoptosis by Modulating the Endoplasmic Reticulum Homeostasis Pathway
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Journal Articles

Probing β-Cell Biology in Space and Time

Rafael Arrojo e Drigo
Journal: Diabetes
Diabetes 2021;70(10):2163–2173
DOI: https://doi.org/10.2337/dbi21-0008
Published: 27 September 2021
View article titled, Probing β-Cell Biology in Space and Time
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Meeting Abstracts

32-OR: Receptor-Mediated Gq Signaling in Adipocytes as a Critical Modulator of Systemic Glucose and Lipid Homeostasis

TAKEFUMI KIMURA, SAI PRASAD PYDI, LEI WANG, YINGHONG CUI, OKSANA GAVRILOVA, JÜRGEN WESS
Journal: Diabetes
Diabetes 2021;70(Supplement_1):32-OR
DOI: https://doi.org/10.2337/db21-32-OR
Published: 01 June 2021
View article titled, 32-OR: Receptor-Mediated Gq Signaling in Adipocytes as a Critical Modulator of Systemic Glucose and Lipid Homeostasis
Meeting Abstracts

1157-P: Brainstem Neurons Regulating Energy Homeostasis

VARUN M. BHAVE, MICHAEL J. HILL-OLIVA, NACHIKET KAMATKAR, SRIKANTA CHOWDHURY, ALEXANDER R. NECTOW
Journal: Diabetes
Diabetes 2021;70(Supplement_1):1157-P
DOI: https://doi.org/10.2337/db21-1157-P
Published: 01 June 2021
View article titled, 1157-P: Brainstem Neurons Regulating Energy Homeostasis
Meeting Abstracts

205-LB: HGFAC Is a ChREBP-Regulated Hepatokine That Enhances Glucose and Lipid Homeostasis

ASHOT SARGSYAN, LUDIVINE DORIDOT, SARAH A. HANNOU, WENXIN TONG, HARINI SRINIVASAN, RACHAEL IVISON, RUBY MONN, HENRY H. KOU, JONATHAN HALDEMAN, INNA ASTAPOVA, LINUS T. TSAI, MARK A. HERMAN
Journal: Diabetes
Diabetes 2021;70(Supplement_1):205-LB
DOI: https://doi.org/10.2337/db21-205-LB
Published: 01 June 2021
View article titled, 205-LB: HGFAC Is a ChREBP-Regulated Hepatokine That Enhances Glucose and Lipid Homeostasis
Meeting Abstracts

225-LB: Targeting ß-Cell Endoplasmic Reticulum (ER) TALK-1 Channels to Restore Ca2+ Homeostasis and Reduce ER Stress in Diabetes

ARYA Y. NAKHE, PRASANNA DADI, DAVID WESTOVER, EMILY DAYS, JEROD DENTON, DAVID JACOBSON
Journal: Diabetes
Diabetes 2021;70(Supplement_1):225-LB
DOI: https://doi.org/10.2337/db21-225-LB
Published: 01 June 2021
View article titled, 225-LB: Targeting ß-Cell Endoplasmic Reticulum (ER) TALK-1 Channels to Restore Ca2+ Homeostasis and Reduce ER Stress in Diabetes
Meeting Abstracts

260-OR: The L-Cell Clock Is Required for Circadian GLP-1 Secretion and Maintenance of Intestinal Homeostasis

SARAH E. MARTCHENKO, ALEXANDRE MARTCHENKO, ANDREW BIANCOLIN, PATRICIA L. BRUBAKER
Journal: Diabetes
Diabetes 2021;70(Supplement_1):260-OR
DOI: https://doi.org/10.2337/db21-260-OR
Published: 01 June 2021
View article titled, 260-OR: The L-Cell Clock Is Required for Circadian GLP-1 Secretion and Maintenance of Intestinal Homeostasis
Meeting Abstracts

230-LB: Differential Roles of Beta-Cell IP3R and RyR ER Ca2+ Channels in Tunicamycin-Induced Disruption of Beta-Cell Ca2+ Homeostasis

IRINA ZHANG, VISHAL S. PAREKH, JUAN J. LEON, LESLIE S. SATIN
Journal: Diabetes
Diabetes 2021;70(Supplement_1):230-LB
DOI: https://doi.org/10.2337/db21-230-LB
Published: 01 June 2021
View article titled, 230-LB: Differential Roles of Beta-Cell IP3R and RyR ER Ca2+ Channels in Tunicamycin-Induced Disruption of Beta-Cell Ca2+ Homeostasis